• Title/Summary/Keyword: 기초대사

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Convergence Study on the Experience of a Community Based Participatory Research leader using the BeHaS Program for Elderly Living Alone (독거노인을 위한 베하스 프로그램을 활용한 지역사회기반 참여연구 리더 경험에 관한 융합적 연구)

  • Kim, Jong Im;Kim, Sun Ae;Kim, Jiyoung
    • Journal of the Korea Convergence Society
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    • v.12 no.1
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    • pp.293-303
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    • 2021
  • This study aimed to confirm the nature of the experiences of elderly living alone who participated in the BeHaS program using community-based participatory research. 6 elderly living alone with metabolic syndrome participated as participants, and they played a role as a leader when conducting the 12 weeks BeHaS program as a community-based participatory study. Data was collected using focus group interview. As a result, Six categories were derived; 'the burden of becoming a research participant', 'knowing a new program', 'getting into the BeHaS program', 'having a new leadership', 'knowing about metabolic syndrome health care', 'Feeling worth through a changed self'. Therefore, this study has identified the nature of the experience of participating in the BeHaS program for metabolic syndrome through a community participation-based study targeting the elderly living alone, and it will be able to provide basic data for the operation and program settlement strategies in the Community of the BeHaS program in the future.

Metabolic Correlates of Temperament Factors of Personality (기질적 성격요인과 국소 뇌포도당대사의 상관연구: 성별에 따른 차이)

  • Park, Hyun-Soo;Cho, Sang-Soo;Yoon, Eun-Jin;Bang, Seong-Ae;Kim, Yu-Kyeong;Kim, Sang-Eun
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.4
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    • pp.280-290
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    • 2007
  • Purpose: Gender differences in personality are considered to have biological bases. In an attempt to understand the gender differences of personality on neurobiological bases, we conducted correlation analyses between regional brain glucose metabolism and temperament factors of personality in males and females. Materials and Methods: Thirty-six healthy right-handed volunteers (18 males, 33.8$\pm$17.6 y; 18 females, 36.2$\pm$20.4 y) underwent FDG PET at resting state. Three temperament factors of personality (novelty seeking (NS), harm avoidance (HA), reward dependence (RD)) were assessed using Cloninger's 240-item Temperament and Character Inventory (TCD within 10 days of FOG PET scan. Correlation between regional glucose metabolism and each temperament factor was tested using SPM2. Results: In males, a significant negative correlation between NS score and glucose metabolism was observed in the bilateral superior temporal gyri, the hippocampus and the insula, while it was found in the bilateral middle frontal gyri, the right superior temporal gyrus and the left cingulate cortex and the putamen in females. A positive HA correlation was found in the right midbrain and the left cingulate gyrus in males, but in the bilateral basal ganglia in females. A negative RD correlation was observed in the right middle frontal and the left middle temporal gyri in males, while the correlation was found in the bilateral middle frontal gyri and the right basal ganglia and the superior temporal gyrus in females. Conclusion: These data demonstrate different cortical and subcortical metabolic correlates of temperament factors of personality between males and females. These results may help understand biological substrate of gender differences in personality and susceptibility to neuropsychiatric illnesses.

Change of Recommended Energy Intake for Korea (한국인의 에너지 섭취권장량 변화)

  • Na, Hyeon-Ju;Kim, Mi-Jeong;Kim, Young-Nam
    • Journal of Korean Home Economics Education Association
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    • v.23 no.3
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    • pp.121-138
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    • 2011
  • This research examined the amounts and methods change of recommended energy intake(REI) from 1962's recommended dietary intakes for Korean to 2010's dietary reference intakes for Koreans. REI is composed of 3 factors, such basal metabolic rate(or Resting Energy Expenditure, REE), activity energy, and thermogenic effect of foods. The first 1962 calculation formula of REI was weight based formula, that of 95's was the weight based REE multiplied by activity coefficient, and the recent one of 2005's(Estimated Energy Requirement: EER) was age, height. weight, and the activity level applying formula derived from the energy expenditure data by doubly labeled water technique(DLW). During the 50 years or so, REIs were reduced in all age groups, according to the activity(labor) strength and hour were reduced. The individual REI calculation method was introduced in 1995, and individual REI calculation was recommended since to prevent obesity. For the better REI estimation for Koreans, REI calculation formula derived from our peoples' DLW energy expenditure data is required.

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A Study of Physiological Changes by The Types of Paralysis Model in Activity Daily of Living (마비모델 유형별 일상생활활동 수행 시 생리적 변화 연구)

  • Sim, Kyoung-Bo;Kim, Dong-Hyun;Kim, Hee-Jung;Moon, Jung-In;Kim, Hyoung-Min
    • The Journal of Korean society of community based occupational therapy
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    • v.1 no.2
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    • pp.21-30
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    • 2011
  • The previous studies were prevalent a study of treatment like a environmental modification or compensative approach and intervention which used in today to paralyzed patients. These interventions were related with occupational therapy widely. The purpose of this study is to provide a basic datum for environmental modification, compensative approach, and intervention observing physiological changes which is shown in early paralyze patients. The subjects were 40 students who were 20 female and 20 male in a college. The students were devided into hemiplegic and paraplegic model. The model was designed using a experimental cloths. A instrument to measure body composition was a precision instrument. The results of the study were as follow: First, there was no different homogeneity between activity daily of living of hemiplegic and paraplegic model. Second, there was a significant different body water and basal metabolic rate between before and after activity daily of living of hemiplegic model. Third, there was a significant different body water and basal metabolic rate between before and after activity daily of living of paraplegic model. Forth, there were no significant different physiological change between after activity daily of living of hemiplegic model and paraplegic model. We observed early changes of body composition using a hemiplegic and paraplegic model. We could know it was reduced body water rate and basal metabolic rate in regardless of type of paralysis. Therefore, it is important to know these physiological changes of paralyzed patients and improve body water and basal metabolic rate of the patients.

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A Study on Risk Factors of Metabolic Syndrome and Health Behaviors in a Region - 2014 community health survey - (일 지역 대사증후군 위험인자와 건강행태에 관한 연구 -2014 지역사회건강조사-)

  • Ahn, Ok-hee;Choi, Seong-hui;Kim, Seo-Hyeon;Ryu, Si-Ok;Choi, Young-Mi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.12
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    • pp.218-225
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    • 2016
  • Recently, Korea has undergone rapid social and economic development, and with that came various changes in living habits and disease patterns; the nation, accordingly, has been alerted to the associated risks of chronic ailments. As risk factors of metabolic syndrome commonly include causal factors of chronic diseases, prevention is important. The prevalence of metabolic syndrome in Korean adults is 22.4%, which comprises a large portion of the whole disease (Korean National Health and Nutrition Examination Survey, 2013). This study aims to examine the elements of healthy living practices by analyzing the risk factors of metabolic syndrome and health behaviors, and provide basic materials to contribute to the activation of health promotion. Among 12,481 subjects of the source data from the 2014 community health survey, which was performed on adults aged 19 and over in Jeonlabuk-do, 12,185 people were analyzed in this study using SPSS 23.0. There were significant differences with respect to sex, smoking status, age, education level, and number of days of physical activity among the results of the difference of the risk factors of the metabolic syndrome according to the characteristics of the health behavior of the subjects. Of the risk factors for metabolic syndrome, this study emphasized the necessity of strategies to promote health programs regarding the management of drinking, smoking, physical activities, depression, subjective health condition and quality of life to the group of those with dyslipidemia, hypertension, and diabetes.

Conserved Genes and Metabolic Pathways in Prokaryotes of the Same Genus (동일한 속 원핵생물들의 보존 유전자와 대사경로)

  • Lee, Dong-Geun;Lee, Sang-Hyeon
    • Journal of Life Science
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    • v.29 no.1
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    • pp.123-128
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    • 2019
  • The use of 16S rDNA is commonplace in the determination of prokaryotic species. However, it has limitations, and there are few studies at the genus level. We investigated conserved genes and metabolic pathways at the genus level in 28 strains of 13 genera of prokaryotes using the COG database (conserved genes) and MetaCyc database (metabolic pathways). Conserved genes compared to total genes (core genome) at the genus level ranged from 27.62%(Nostoc genus) to 71.76%(Spiribacter genus), with an average of 46.72%. The lower ratio of core genome meant the higher ratio of peculiar genes of a prokaryote, namely specific biological activities or the habitat may be varied. The ratio of common metabolic pathways at the genus level was higher than the ratio of core genomes, from 58.79% (Clostridium genus) to 96.31%(Mycoplasma genus), with an average of 75.86%. When compared among other genera, members of the same genus were positioned in the closest nodes to each other. Interestingly, Bacillus and Clostridium genera were positioned in closer nodes than those of the other genera. Archaebacterial genera were grouped together in the ortholog and metabolic pathway nodes in a phylogenetic tree. The genera Granulicella, Nostoc, and Bradyrhizobium of the Acidobacteria, Cyanobacteria, and Proteobacteria phyla, respectively, were grouped in an ortholog content tree. The results of this study can be used for (i) the identification of common genes and metabolic pathways at each phylogenetic level and (ii) the improvement of strains through horizontal gene transfer or site-directed mutagenesis.

Pathophysiological Functions of Deubiquitinating Enzymes in Obesity and Related Metabolic Diseases (탈유비퀴틴화 효소 DUBs의 비만 및 대사 관련 질환에서 병태생리학적 기능)

  • Lee, Seul Gi;Kwon, Taeg Kyu
    • Journal of Life Science
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    • v.32 no.6
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    • pp.476-481
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    • 2022
  • Ubiquitin signaling regulates virtually all aspects of eukaryotic biology and dynamic processes in which protein substrates are modified by ubiquitin. To regulate these processes, deubiquitinating enzymes (DUBs) cleave ubiquitin or ubiquitin-like proteins from these substrates. DUBs have been implicated in the pathogenesis of cancer, leading to the development of increasing numbers of small-molecule DUB inhibitors. On the other hand, recent studies have focused on the function of DUBs in metabolic diseases such as obesity, diabetes, and fatty liver diseases. DUBs play a positive or negative role in the progression and development of metabolic diseases. Their involvement in cell pathology and regulation of major transcription factors in metabolic syndrome has been examined in vitro and in animal and human biopsies. UCH, USP7, and USP19 were linked to adipocyte differentiation, body weight gain, and insulin resistance in genetic or diet-induced obesity. CYLD, USP4, and USP18 were found to be closely associated with fatty liver diseases. In addition, these liver diseases were accompanied by body weight change in certain cases. Collectively, in this review, we discuss the current understanding of DUBs in metabolic diseases with a particular focus on obesity. We also provide basic knowledge and regulatory mechanisms of DUBs and suggest these enzymes as therapeutic targets for metabolic diseases.

소중한 당신의 체중계_호르몬을 알면 날씬해진다 - 균형잡힌 호르몬 날씬해지는 지름길

  • Park, Yun-Chan
    • 건강소식
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    • v.36 no.11
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    • pp.6-8
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    • 2012
  • 천고마비의 계절, 하늘은 높고 말은 살찐다는 가을이다. 가을이 되면 유난히 왕성해지는 식욕 때문에 다이어트에 어려움을 겪은 사림들이 많다. 이처럼 가을에 식욕이 늘어나는 이유는 기온 변화에 따른 신체의 반응 때문이다. 기온이 떨어지면 우리 몸은 체온을 유지하기 위해 기초 대사량이 5% 정도 증가하고, 활동하기 좋은 기온이라 상대적으로 활동량이 증가하면서 공복감을 빨리 느끼게 된다. 또, 추운 겨울을 대비해 우리 몸이 본능적으로 체지방을 늘리기 위해 식욕이 증가하기도 한다.

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더위에 지친 젖소의 사양관리

  • Choe, Sun-Muk
    • Feed Journal
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    • v.2 no.9
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    • pp.104-107
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    • 2004
  • 하절기 사육환경 온도가 상승함에 따라 젖소가 받는 스트레스로 인한 생산성 저하는 저능력우 보다 고능력우에서 증가하게 되는데, 이는 높은 산유량을 유지하는데 필요한 기초 에너지 소모가 증가하여 체온이 증가하기 때문이다. 또한 고능력우들은 높은 산유량을 유지하기 위하여 더 많은 에너지와 영양소를 섭취하여야만 하는데 고온스트레스로 인하여 사료 섭취량이 감소, 에너지 부족현상을 다른 젖소들보다 더 심각하게 겪으므로 대사성 질병 발생이나 번식능력의 저하가 현저히 나타나기 때문이다(외기의 적정온도 : 4~24℃). (중략)

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1969년도 가금영양학시험 하일라이트

  • P.W. 왈드로우프
    • KOREAN POULTRY JOURNAL
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    • v.3 no.5 s.19
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    • pp.103-107
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    • 1971
  • 1969년도에 가금영양학자들은 가금영양학의 기초지식과 이의 응용분야에 대해 많은 연구결과를 발표하였다. 오늘날 가금영양학에 관한 연구는 크게 두 가지 분야로 대별된다. 첫째는 주요영양소의 생물학적 효율에 대한 보다 정확한 데이터를 얻는것과 특정 영양소의 정확한 요구량을 조사하는 기술 및 시험이며, 둘째 분야는 영양소들간의 상호작용과 대사과정의 효율성에 관한 정확하고 폭넓은 지식을 얻는 것이다. 이 시험집은 1969년도에 가금학자들이 연구발표한 가금영양학에 관한 하이라이트이다. 지면 관계로 전시험결과를 모두 수록치 못하였으나 사료공장이나 농장의 실제응용에 흥미가 많을 것으로 생각된다.

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