• Title/Summary/Keyword: 기준 모델

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Effectiveness of Two-dose Varicella Vaccination: Bayesian Network Meta-analysis

  • Kwan Hong;Young June Choe;Young Hwa Lee;Yoonsun Yoon;Yun-Kyung Kim
    • Pediatric Infection and Vaccine
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    • v.31 no.1
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    • pp.55-63
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    • 2024
  • Purpose: A 2-dose varicella vaccination strategy has been introduced in many countries worldwide, aiming to increase vaccine effectiveness (VE) against varicella infection. In this network meta-analysis, we aimed to provide a comprehensive evaluation and an overall estimated effect of varicella vaccination strategies, via a Bayesian model. Methods: For each eligible study, we collected trial characteristics, such as: 1-dose vs. 2-dose, demographic characteristics, and outcomes of interest. For studies involving different doses, we aggregated the data for the same number of doses delivered into one arm. The preventive effect of 1-dose vs. 2-dose of varicella vaccine were evaluated in terms of the odds ratio (OR) and corresponding equal-tailed 95% confidence interval (95% CI). Results: A total of 903 studies were retrieved during our literature search, and 25 interventional or observational studies were selected for the Bayesian network meta-analysis. A total of 49,265 observed individuals were included in this network meta-analysis. Compared to the 0-dose control group, the OR of all varicella infections were 0.087 (95% CI, 0.046-0.164) and 0.310 (95% CI, 0.198-0.484) for 2-doses and one-dose, respectively, which corresponded to VE of 69.0% (95% CI, 51.6-81.2) and VE of 91.3% (95% CI, 83.6-95.4) for 1- and 2-doses, respectively. Conclusions: A 2-dose vaccine strategy was able to significantly reduce varicella burden. The effectiveness of 2-dose vaccination on reducing the risk of infection was demonstrated by sound statistical evidence, which highlights the public health need for a 2-dose vaccine recommendation.

Estimating the Impact of DMZ Punchbowl Trail as a National Forest Trail on Local Economy using the Regional Input-Output Model (지역산업연관모델을 이용한 국가숲길의 지역경제 파급효과 분석: DMZ펀치볼둘레길을 중심으로)

  • Sugwang Lee;Jae Dong Yang;Jeonghee Lee
    • Journal of Korean Society of Forest Science
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    • v.113 no.2
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    • pp.170-186
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    • 2024
  • This study was conducted to identify the usage characteristics of the DMZ Punchbowl Trail (DPT) as a national forest trail (NFT) and to estimate its ripple effects on the local economy. The objective of this study is to provide policy implications for sustainable operational management. Out of the 500 questionnaires distributed, 215 respondents provided their complete travel itineraries and expenditures. The respondents, mainly aged 50 and above and residing in the Seoul Metropolitan Area, spend 3.5 hours of travel time to the DPT. Together with their families, the respondents typically spend approximately 4 hours for leisurely activities, primarily appreciation of scenic views and relaxation by visiting the "O-yubatgil." Furthermore, they extend their travels to other parts of Gangwon Province, where the DPT is situated. Within Gangwon Province, Yanggu County is the most visited destination. The respondents reported a notably higher average expenditure per visitor compared with the typical local walking tourists. Estimates show that the DPT generates an annual average of KRW 2.1 billion in direct expenditure (based on an average of 10,000 visitors for over five years), KRW 2.8 billion in production, and KRW 1.3 billion in added value, and it has created 40 jobs in Gangwon Province. The results of this study lies in empirically determining the specific economic scale and ripple effects of DPT as an NFT in the major sector, which occupies a significant portion of the Gangwon Province's local economy. The results will be instrumental in validating NFT policies and informing policy making for sustainable forest utilization.

A User based Collaborative Filtering Recommender System with Recommendation Quantity and Repetitive Recommendation Considerations (추천 수량과 재 추천을 고려한 사용자 기반 협업 필터링 추천 시스템)

  • Jihoi Park;Kihwan Nam
    • Information Systems Review
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    • v.19 no.2
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    • pp.71-94
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    • 2017
  • Recommender systems reduce information overload and enhance choice quality. This technology is used in many services and industry. Previous studies did not consider recommendation quantity and the repetitive recommendations of an item. This study is the first to examine recommender systems by considering recommendation quantity and repetitive recommendations. Only a limited number of items are displayed in offline stores because of their physical limitations. Determining the type and number of items that will be displayed is an important consideration. In this study, I suggest the use of a user-based recommender system that can recommend the most appropriate items for each store. This model is evaluated by MAE, Precision, Recall, and F1 measure, and shows higher performance than the baseline model. I also suggest a new performance evaluation measure that includes Quantity Precision, Quantity Recall, and Quantity F1 measure. This measure considers the penalty for short or excess recommendation quantity. Novelty is defined as the proportion of items in a recommendation list that consumers may not experience. I evaluate the new revenue creation effect of the suggested model using this novelty measure. Previous research focused on recommendations for customer online, but I expand the recommender system to cover stores offline.

Dose Assessment of Orbital Adnexa in Electron Beam Therapy for Orbital Lymphoma (안와림프종의 전자선 치료 시 안구 부속기관에 대한 선량평가)

  • Dong Hwan Kim;Yong In Cho
    • Journal of the Korean Society of Radiology
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    • v.18 no.3
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    • pp.283-292
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    • 2024
  • Radiation side effects and complications on the ocular adnexa during electron beam therapy for orbital lymphoma can increase the incidence of posterior subcapsular cataracts. This study simulated a medical linear accelerator and a mathematical model of the eye using monte carlo simulations to evaluate the dose to the ocular adnexa and compare the shielding effectiveness on different parts of the ocular adnexa based on lens shield thickness. The dose assessment results of the ocular adnexa showed that the lens's sensitive area had the highest absorbed dose distribution when no shield was used, followed by the lens's non-sensitive area, the anterior chamber, vitreous humor, cornea, and eyelid in descending order. With the use of a shield, a 2 mm thick shield demonstrated a dose reduction effect of over 90% in the lens's sensitive area, over 83% in the non-sensitive area and anterior chamber, and a dose reduction effect of 30 to 62% in the vitreous body, cornea, and eyelid. For dose reduction in the lens's sensitive area during electron beam therapy for orbital lymphoma, it is necessary to use a shield of at least 2 mm thickness. Additionally, shielding strategies considering the thickness and area of the shield for other ocular adnexa besides the lens are required.

Microbiological Hazard Analysis for HACCP System Application to Vinegared Pickle Radishes (식초절임 무의 HACCP 시스템 적용을 위한 미생물학적 위해 분석)

  • Kwon, Sang-Chul
    • Journal of Food Hygiene and Safety
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    • v.28 no.1
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    • pp.69-74
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    • 2013
  • This study has been performed for 150 days from February 1 - June 31, 2012 aiming at analyzing biologically hazardous factors in order to develop HACCP system for the vinegared pickle radishes. A process chart was prepared as shown on Fig. 1 by referring to manufacturing process of manufacturer of general vinegared pickle radishes regarding process of raw agricultural products of vinegared pickle radishes, used water, warehousing of additives and packing material, storage, careful selection, washing, peeling off, cutting, sorting out, stuffing (filling), internal packing, metal detection, external packing, storage and consignment (delivery). As a result of measuring Coliform group, Staphylococcus aureus, Salmonella spp., Bacillus cereus, Listeria Monocytogenes, E. coli O157:H7, Clostridium perfringens, Yeast and Mold before and after washing raw radishes, Bacillus cereus was $5.00{\times}10$ CFU/g before washing but it was not detected after washing and Yeast and Mold was $3.80{\times}10^2$ CFU/g before washing but it was reduced to 10 CFU/g after washing and other pathogenic bacteria was not detected. As a result of testing microorganism variation depending on pH (2-5) of seasoning fluid (condiment), pH 3-4 was determined as pH of seasoning fluid as all the bacteria was not detected in pH3-4. As a result of testing air-borne bacteria (number of general bacteria, colon bacillus, fungus) depending on each workplace, number of microorganism of internal packing room, seasoning fluid processing room, washing room and storage room was detected to be 10 CFU/Plate, 2 CFU/Plate, 60 CFU/Plate and 20 CFU/Plate, respectively. As a result of testing palm condition of workers, as number of general bacteria and colon bacillus was represented to be high as 346 $CFU/Cm^2$ and 23 $CFU/Cm^2$, respectively, an education and training for individual sanitation control was considered to be required. As a result of inspecting surface pollution level of manufacturing facility and devices, colon bacillus was not detected in all the specimen but general bacteria was most dominantly detected in PP Packing machine and Siuping machine (PE Bulk) as $4.2{\times}10^3CFU/Cm^2$, $2.6{\times}10^3CFU/Cm^2$, respectively. As a result of analyzing above hazardous factors, processing process of seasoning fluid where pathogenic bacteria may be prevented, reduced or removed is required to be controlled by CCP-B (Biological) and threshold level (critical control point) was set at pH 3-4. Therefore, it is considered that thorough HACCP control plan including control criteria (point) of seasoning fluid processing process, countermeasures in case of its deviation, its verification method, education/training and record control would be required.

The Effects of 8-weeks Jeol Meditation Program on Stress, Depression and Cardiovascular Risk Factors in Women (8주간의 절명상 프로그램이 여성의 스트레스, 우울 및 심혈관 위험인자에 미치는 효과)

  • Jung, HwanSug;Kang, YuneSik
    • Journal of agricultural medicine and community health
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    • v.38 no.3
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    • pp.163-173
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    • 2013
  • Objectives: There has been an increase in the use of mind-body therapies to control cardiovascular risk factors recently. This trial was designed to determine whether the 'jeol'(Korean Buddhists' prostration) meditation program, as a new mind-body intervention, was effective in managing stress, depression and controlling cardiovascular risk factors in women working at a geriatric hospital. Methods: We conducted a randomized controlled trial to determine whether the 'jeol' meditation program could improve stress, anxiety, depression, and cardiovascular risk factors in women. We randomly assigned 57 participants to the intervention(29 participants) or control(28 participants) group. The subjects in the intervention group participated in a group Jeol meditation program once weekly, and practiced at home. The following variables were assessed: stress(Psychosocial Wellbeing Index), depression(Beck's Depression Inventory), body mass index(BMI), waist circumference, hemoglobin A1c(HbA1c), homeostasis model assessment(HOMA), low-density lipoprotein(LDL) cholesterol, high-density lipoprotein(HDL) cholesterol, and triglyceride were assessed. Results: After the 8-week program, 2 participants from the intervention group and 1 from the control group dropped out. The subjects in the intervention group exhibited decreased scores for stress(t=5.102, p<0.01), depression(t=5.259, p<0.01), BMI(t=2.942, p=0.007), and waist circumference(t=2.582, p=0.016); however these scores did not demonstrate a significant decrease in participants of the control group. The other variables showed no significant difference between the groups. Conclusion: The 'jeol' meditation program evidently reduced stress, anxiety, depression, body weight, and waist circumference in women, which suggests that this program could be employed as a mind-body therapies.

Spatiotemporal Assessment of the Late Marginal Heading Date of Rice using Climate Normal Data in Korea (평년 기후자료를 활용한 국내 벼 안전출수 한계기의 시공간적 변화 평가)

  • Lee, Dongjun;Kim, Junhwan;Kim, Kwang Soo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.16 no.4
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    • pp.316-326
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    • 2014
  • Determination of the late marginal heading date (LMHD), which would allow estimation of the late marginal seeding date and the late marginal transplanting date, would help identification of potential double cropping areas and, as a result, establishment of cropping systems. The objective of this study was to determine the LMHD at 51 sites in Korea. For these sites, weather data were obtained from 1971 to 2000 and from 1981 to 2010, which represent past and current normal climate conditions, respectively. To examine crop productivity on the LMHD, climatic yield potential (CYP) was determined to represent the potential yield under a given climate condition. The LMHD was calculated using accumulated temperature for 40 days with threshold values of $760^{\circ}C$, $800^{\circ}C$, $840^{\circ}C$ and $880^{\circ}C$. The value of CYP on a given LMHD was determined using mean temperature and sunshine duration for 40 days from the LMHD. The value of CYP on the LMHD was divided by the maximum value of CYP (CYPmax) in a season to represent the relative yield on the LMHD compared with the potential yield in the season. Our results indicated that the LMHD was delayed at most sites under current normal conditions compared with past conditions. Spatial variation of the LMHD differed by the threshold temperature. Overall, the minimum value of CYP/CYPmax was 81.8% under all of given conditions. In most cases, the value of CYP/CYPmax was >90%, which suggested that yield could be comparable to the potential yield even though heading would have occurred on the LMHD. When the LMHD could be scheduled later without considerable reduction in yield, the late marginal transplanting date could also be delayed accordingly, which would facilitate doublecropping in many areas in Korea. Yield could be affected by sudden change of temperature during a grain filling period. Yet, CYP was calculated using mean temperature and sunshine duration for 40 days after heading. Thus, the value of CYP/CYPmax may not represent actual yield potential due to change of the LMHD, which suggested that further study would be merited to take into account the effect of weather events during grain filling periods on yield using crop growth model and field experiments.

An Implementation of Lighting Control System using Interpretation of Context Conflict based on Priority (우선순위 기반의 상황충돌 해석 조명제어시스템 구현)

  • Seo, Won-Il;Kwon, Sook-Youn;Lim, Jae-Hyun
    • Journal of Internet Computing and Services
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    • v.17 no.1
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    • pp.23-33
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    • 2016
  • The current smart lighting is shaped to offer the lighting environment suitable for current context, after identifying user's action and location through a sensor. The sensor-based context awareness technology just considers a single user, and the studies to interpret many users' various context occurrences and conflicts lack. In existing studies, a fuzzy theory and algorithm including ReBa have been used as the methodology to solve context conflict. The fuzzy theory and algorithm including ReBa just avoid an opportunity of context conflict that may occur by providing services by each area, after the spaces where users are located are classified into many areas. Therefore, they actually cannot be regarded as customized service type that can offer personal preference-based context conflict. This paper proposes a priority-based LED lighting control system interpreting multiple context conflicts, which decides services, based on the granted priority according to context type, when service conflict is faced with, due to simultaneous occurrence of various contexts to many users. This study classifies the residential environment into such five areas as living room, 'bed room, study room, kitchen and bath room, and the contexts that may occur within each area are defined as 20 contexts such as exercising, doing makeup, reading, dining and entering, targeting several users. The proposed system defines various contexts of users using an ontology-based model and gives service of user oriented lighting environment through rule based on standard and context reasoning engine. To solve the issue of various context conflicts among users in the same space and at the same time point, the context in which user concentration is required is set in the highest priority. Also, visual comfort is offered as the best alternative priority in the case of the same priority. In this manner, they are utilized as the criteria for service selection upon conflict occurrence.

Seismic Design of Columns in Inverted V-braced Steel Frames Considering Brace Buckling (가새좌굴을 고려한 역 V형 가새골조의 기둥부재 내진설계법)

  • Cho, Chun-Hee;Kim, Jung-Jae;Lee, Cheol-Ho
    • Journal of Korean Society of Steel Construction
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    • v.22 no.1
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    • pp.1-12
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    • 2010
  • According to the capacity design concept which forms the basis of the current steel seismic codes, the braces in concentrically braced frames (CBFs) should dissipate seismic energy through cyclic tension yielding and cyclic compression buckling while the beams and the columns should remain elastic. Brace buckling in inverted V-braced frames induces unbalanced vertical forces which, in turn, impose the additional beam moments and column axial forces. However, due to difficulty in predicting the location of buckling stories, the most conservative approach implied in the design code is to estimate the column axial forces by adding all the unbalanced vertical forces in the upper stories. One alternative approach, less conservative and recommended by the current code, is to estimate the column axial forces based on the amplified seismic load expected at the mechanism-level response. Both are either too conservative or lacking technical foundation. In this paper, three combination rules for a rational estimation of the column axial forces were proposed. The idea central to the three methods is to detect the stories of high buckling potential based on pushover analysis and dynamic behavior. The unbalanced vertical forces in the stories detected as high buckling potential are summed in a linear manner while those in other stories are combined by following the SRSS(square root of sum of squares) rule. The accuracy and design advantage of the three methods were validated by comparing extensive inelastic dynamic analysis results. The mode-shape based method(MSBM), which is both simple and accurate, is recommended as the method of choice for practicing engineers among the three.

An analytical study on the fire characteristics of the small tunnel with large smoke exhaust port (대배기구 배연방식을 적용한 소형차 전용 터널의 화재특성에 관한 해석적 연구)

  • Yoo, Ji-Oh;Kim, Jin-Su;Rhee, Kwan-Seok
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.19 no.3
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    • pp.375-388
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    • 2017
  • In order to solve the traffic congest and environmental issues, small-cross section tunnel for small car only is increasing, but there is not standard for installation of disaster prevention facility. In this study, in order to investigate the behavioral characteristics of thermal environment and smoke in a small cross section tunnels with a large port exhaust ventilation system, the A86, the U-Smartway and the Seobu moterawy tunnel, Temperature and CO concentration in case of fire according to cross sectional area, heat release rate and exhaust air flow rate were analyzed by numerical analysis and the results were as follows. As the cross-sectional area of the tunnel decreases, the temperature of the fire zone increases and the rate of temperature rise is not significantly affected by heat release rate. However, there is a difference depending on the change of the exhaust air flow rate. In the case of applying the exhaust air flow rate $Q_3+2.5Ar$ of the large port exhaust ventilation system, the temperature of the fire zone was 7.1 times for A86 ($Ar=25.3m^2$) and 5.4 time for U-smartway ($Ar=37.32m^2$) by Seobu moterway tunnel ($Ar=46.67m^2$). The CO concentration of fire zone also showed the same tendency. The A86 tunnels were 10.7 times and the U-Smartways were 9.5 times more than the Seobu moterway. Therefore, in the case of a small section tunnel, the thermal environment and noxious gas concentration due to the reduction of the cross-sectional area are expected to increase significantly more than the cross-sectional reduction rate.