• Title/Summary/Keyword: 기저형

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Analysis of ITS DNA Sequences of the Viola albida Complex (태백제비꽃군 ITS DNA 염기서열 분석)

  • Whang, Sung-Soo
    • Korean Journal of Plant Resources
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    • v.19 no.5
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    • pp.628-633
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    • 2006
  • ITS DNA sequences from five individuals, representative of five groups designated according to the degree of leaf teeth and lobes from simple to palmate compound leaf in the Viola albida complex, established and further analysed in order to solve the taxonomic difficulty. A total 702 bp was sequenced at the 5.8S ribosomal DNA and internal transcribed spacer 1 and 2. The 5.8S coding region is 163 bp, and has no sequence variations. The ITS1 and ITS2 noncoding regions have a little bit sequence variations, and those were further analysed by the methods of the analysis of variance (ANOVA), the analysis of sequence divergence and the phylogenetic analysis. The result of ANOVA showed no significant differences among individuals investigated. The analysis of sequence divergence with Kimura 2-parameter distance revealed that in-groups showed much less than 0.05 in absolute value among individuals, while two out groups more than 0.05, V. grypoceras and V. orientalis. This result appeared that the sequence divergence among in-groups was not yet occurred in the species level but situated at somewhere below the species level. In the phylogenetic analysis, two outgroups formed the basal clades in order. Five individuals in-groups formed a clade. The clade was, however, not very robust as around 50% in bootstrap value, suggesting that this result was not meaningful in the phylogenetic point of views.

Design of Optimized RBFNNs based on Night Vision Face Recognition Simulator Using the 2D2 PCA Algorithm ((2D)2 PCA알고리즘을 이용한 최적 RBFNNs 기반 나이트비전 얼굴인식 시뮬레이터 설계)

  • Jang, Byoung-Hee;Kim, Hyun-Ki;Oh, Sung-Kwun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.24 no.1
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    • pp.1-6
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    • 2014
  • In this study, we propose optimized RBFNNs based on night vision face recognition simulator with the aid of $(2D)^2$ PCA algorithm. It is difficult to obtain the night image for performing face recognition due to low brightness in case of image acquired through CCD camera at night. For this reason, a night vision camera is used to get images at night. Ada-Boost algorithm is also used for the detection of face images on both face and non-face image area. And the minimization of distortion phenomenon of the images is carried out by using the histogram equalization. These high-dimensional images are reduced to low-dimensional images by using $(2D)^2$ PCA algorithm. Face recognition is performed through polynomial-based RBFNNs classifier, and the essential design parameters of the classifiers are optimized by means of Differential Evolution(DE). The performance evaluation of the optimized RBFNNs based on $(2D)^2$ PCA is carried out with the aid of night vision face recognition system and IC&CI Lab data.

IMMUNOHISTOCHEMICAL STUDY ON EXPRESSION OF APOPTOSIS RELATED PROTEINS IN DENTIGEROUS CYST AND AMELOBLASTOMA (함치성 낭종 및 법랑아세포종에 있어서 Apoptosis 관련 단백 발현에 관한 면역조직화학적 연구)

  • Choi, Jin-Young
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.22 no.1
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    • pp.15-21
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    • 2000
  • Ameloblasotma is slowly growing, locally invasive neoplasm with a potentially destructive behavior. The epithelium of ameloblastoma is thought to have an intrinsic growth potential and has been shown to present a higher rate of proliferation as compared to odontogenic cysts with low local recurrence rate. The molecular mechanisms that regulate the cell growth and invasion of ameloblastoma cells are unknown. Bcl-2 protein, which prevent apoptosis, is expressed in immortalized ameloblastoma cell line(AM-1)(Harada et al 1998). Expression of bcl-2 protein occurs in tooth germs, whose epithelial component may act as the histogenic precursor of ameloblastoma. Bax is considered as a main effector of apoptosis. Bax forms homodimers and also heterodimers with bcl-2. p53 tumor supressor gene participates not only in cell proliferation control but also in induction of apoptosis. The objective of the present study was to evaluate the apoptosis related protein expression in odontogenic cyst and ameloblastoma. A total of 10 dentigerous cysts and 16 ameloblastomas were used in the present study. Dentigerous cyst showed negative or slight positive for p53 and bcl-2 but strongly positive for bax, ameloblastoma, on the other hand, strongly positive for p53 and bcl-2 but weekly positive for bax. Bcl-2 was expressed for ameloblastoma mainly in outer layer or whole layer of epithelium and for dentigerous cyst mainly in basal layer. The difference in expression of apoptosis related protein in dentigerous cyst and ameloblastoma might explain the peculiar aggressive growth pattern of ameloblastoma.

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Effect and Safety of Replacement Therapy with Insumon in Type 2 Diabetes Mellitus (제2형 당뇨병 환자에 대한 대체 요법 [인슈몬]의 효과 및 안전성)

  • 홍억기;김재수;박준홍;박세정;장학철;한인권
    • KSBB Journal
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    • v.18 no.4
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    • pp.335-339
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    • 2003
  • This research was concentrated to Investigate the effects of Insumon as a newly developed dietary supplement in patients with type 2 diabetes. The average glycated hemoglobin level was dropped from 7.0${\pm}$1.1% to 6.7${\pm}$0.9% after 8 weeks with statistic significance (p=0.0202). For patients of HbA1c over 7%, the average HbA1c significantly decreased from 8.1${\pm}$0.8% to 7.5${\pm}$0.8% (p=0.0171). The average fasting blood glucose level was decreased significantly from 9.5${\pm}$1.2 mmol/L (171.6${\pm}$22.3 mg/dL) to 8.5${\pm}$1.5 mmol/L (152.3${\pm}$26.3 mg/dL) (p=0.0262) after 4 weeks and to 8.8${\pm}$1.5 mmol/L (158.3${\pm}$24.1 mg/dL) (p=0.0445) after 8 weeks in the group of patients of FBG of over 7.8 mmol/L (140 mg/dL). The average HDL cholesterol level was increased significantly after 8 weeks from 1.2${\pm}$0.2 mmol/L (46.5${\pm}$8.6 mg/dL) to 1.3${\pm}$0.3 mmol/L (51.6${\pm}$10.9 mg/dL) (p=0.0007). Thus, these results suggested that patients with type 2 diabetes might benefit by Insumon as a herbal dietary supplement without any serious side effects.

A Study on Hull-Form Design for Ships Operated at Two Speeds (두 가지 속도에서 운항하는 선박의 형상설계에 관한 연구)

  • Kim, Tae Hoon;Choi, Hee Jong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.4
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    • pp.467-474
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    • 2018
  • The purpose of this study is related to automatic hull-form design for ships operating at two speeds. Research was conducted using a series 60 ($C_B=0.6$) ship as a target, which has the most basic ship hull-form. Hull-form development was pursued from the viewpoint of improving resistance performance. In particular, automatic hull-form design for a ship was performed to improve wave resistance, which is closely related to hull-forms. For this purpose, we developed automatic hull-form design software for ships by combining an optimization technique, resistance prediction technique and hull-form modification technique, appling the software developed to a target ship. A sequential quadratic programming method was used for optimization, and a potential-based panel method was used to predict resistance performance. A Gaussian-type modification function was developed and applied to change the ship hull-form. The software developed was used to design a target ship operating at two different speeds, and the performance of the resulting optimized hull was compared with the results of the original hull. In order to verify the validity of the program developed, experimental results obtained in model tests were compared with calculated values by numerical analysis.

Estimation of Exploitable Groundwater in the Jinju Region by Using a Distributed Hydrologic Model (분포형 수문모형을 이용한 진주지역의 지하수 개발가능량 추정)

  • Lee, Jeong Eun;Chung, Il-Moon;Lee, Jeongwoo;Kim, Min Gyu
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.41 no.6
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    • pp.655-662
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    • 2021
  • This study aimed to estimate exploitable groundwater for the sustainable supply of groundwater in the Jinju region of South Gyeongsang Province. As an integrated hydrologic analysis model, SWAT-MODFLOW was used to estimate the distributed groundwater recharge in consideration of land use and soil distribution. As a result of calibration of the model, the coefficient of determination between the observed flow and the simulated flow was 0.75-0.80, which was good. The simulated groundwater recharge rate showed a spatio-temporal distribution due to heterogeneous watershed characteristics. The amount of groundwater recharge shows lower values over winter and spring, but it increases according to the pattern of precipitation in summer and autumn. The calculated average annual groundwater recharge was compared with the result using the baseflow separation method of natural flow, and the deviation of both results was small, within 3 %, confirming the validity of the estimated groundwater recharge. Exploitable groundwater is defined as the amount of recharge corresponding to low flow with 10 years of return period. Therefore, in this study, 14.2 % of the annual precipitation was found to be exploitable as a result of calculating the amount of recharge at a 10-year frequency using a statistical frequency analysis technique.

Angioimmunoblastic T-Cell Lymphoma with Polyclonal Proliferation of Plasma Cells: A Cautionary Note for Flow Cytometry Interpretations (유세포 분석의 주의사항: 혈관면역모세포성 T세포 림프종에서 관찰된 다클론성 형질세포)

  • Shin, Woo Yong;Bang, Hae In;Kim, Jung-Ah;Kim, Jieun;Park, Rojin
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.1
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    • pp.68-72
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    • 2022
  • Angioimmunoblastic T-cell lymphoma (AITL) is a lymphoproliferative disorder of mature T follicular helper cells. Atypical lymphoid cells were observed in the bone marrow of an 80-year-old woman, and the flow cytometric determined immunophenotypes of B-cells were unusual, that is, CD19+, CD20-, and CD22- with lambda light chain restriction. Initially, we suspected BM involvement of B-cell lymphoma based on the presence of abnormal B-cells. However, the patient was diagnosed with AITL involving BM. A re-analysis of flow cytometric immunophenotyping revealed a minor, aberrant T-cell population, and the lambda light chain restriction observed by surface staining was considered non-specific binding. This case demonstrates B-cells in patients with EBV-positive T-cell lymphoma may exhibit immunophenotypes resembling those of plasma cells, and that proliferation of abnormal B-cells or plasma cells could also potentially mask underlying T-cell lymphoma. A more integrated approach is required for accurate diagnosis.

Detection of Respiratoiry Tract Viruses in Busan, 1997-2000 (1997-2000년 부산지역 호흡기계 바이러스의 탐색)

  • 조경순;김영희
    • Korean Journal of Microbiology
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    • v.37 no.4
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    • pp.284-288
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    • 2001
  • Respiratory viruses are one of the most infectious agent in human. Six different respiratory tract viruses were detected from Busan while working on the preventive surveillance in 1997-2000. The isolation rate from suspected specimens were 8.4%. Influenza virus A, B type, parainfluenza virus, adenovirus, mumps virus, and measles virus were examined from throat swabs, serum, and secretions of patients. Influenza A/Sydney/05/97(H3N2)-like, A/Johanesburg/33/94(H3N2)-like, A/Beijing/262/95(H1N1)-like and Influenza B/Beijing/262/95-like, B/Harbin/07/94-like, B/Guangdong/08/93-like were found. Adenovirus serotype 1, 2, 3 and 5 were detected, antibody of mumps both IgM and IgG were shown and outbreaks of measles were confirmed. Different antigenic types of influenza virus were detected every year, one outbreak of parainfluenza in 1999, mumps outbreak in 1999 and 2000, and incidence of measles in 2000 were noticeable. Monthly outbreaks were November through following March with influenza virus, January through June with adenovirus, February through May and December with mumps, April through August and November, December with measles, respectively. The size of isolated viruses were 130 nm with influenza virus B type, non-enveloped, icosahedron with 70 nm with adenovirus, 170 nm with mumps virus and 180 nm with parainfluenza virus in diameter, respectively.

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Studies on Spermatogenesis in Japanese Quail(Coturnix coturnix japonica) (메추리(Coturnix coturnix)의 정자 발생에 관한 연구)

  • 김재홍;박영석
    • Korean Journal of Poultry Science
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    • v.16 no.2
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    • pp.91-100
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    • 1989
  • This study was conducted to observe 1) the changes of cellular association in seminiferous tubles from 2 to 8 weeks of age, and 2) the cycle phenomena of seminiferous epithelia at 14 weeks of age in Japanese quail. Total 80 birds were examined at a week interval from 2 to 8 weeks, and 14 weeks of age. The results were summarized as follows: 1) The body and testis weights showed most prominent increase during 4 to 5 weeks and 6 to 8 weeks of age respectively. And also the diameters of seminiferous tubles were abruptly enlaged during 6 to 8 weeks of age. 2) Genocytes in the seminiferous tubles were still in existence at 3 weeks of age, however they did not come out after 4 weeks of age. Spermatogonia, primary spermatocytes and spermatids made their first arpearances in the seminiferous from 3, 4 and 6 weeks of age, respectively. Spermatozoa were observed for the first time at 7 weeks of age, but full spermatogenic activity was completed from 8 weeks of age. 3) At 14 weeks of age, the average weight at testis was 3.7g and its ratio to the body weight was approximately 3.0 percent. And at this age, average diameter of seminiferous tubules was 192.08 $\mu\textrm{m}$, and average numbers of spermatogonia, spermatocytes, spermatids and spermatozoa within the cross section of seminiferous tubules were 7.74, 40.81, 28.42, 104.55 and 105.98, respectively. Spermatogonia and spermatid were classfied into 2 and 3 types, respectively. 4) At 14 weeks of age, the cycle of seminiferous epithelium could be divided into S stages with following characteristics. (1) Stage I: Seminiferous tubules showing type I and II spermatids. (2) Stage II: Seminiferous tubules showing type III spermatids only. (3) Stage III: Immature spermatozoa gathered near the sertoli cytoplasm. (4) Stage IV: Forming a bundle of 15-20 spematozoa. (5) Stage V: Spermatozoa bundle leaving the sertoli cytoplasm into lumen of the seminferous tubule. 5) Usually 2-3 stages of the seminiferous epithelium cycle were concurrently appeared within a tubular cross section, and frequency of each stage from I to V within cross section of seminiferous tubules were 11.91%, 27.03%, 27.96%, 19.04% and 17.98%, respectively.

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A study on the implementation of Medical Telemetry systems using wireless public data network (무선공중망을 이용한 의료 정보 데이터 원격 모니터링 시스템에 관한 연구)

  • 이택규;김영길
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2000.10a
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    • pp.278-283
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    • 2000
  • As information communication technology developed we could check our blood pressure, pulsation electrocardiogram, SpO2 and blood test easily at home. To check our health at ordinary times is able though interlocking the house medical instrument with the wireless public data network This service will help the inconvenience to visit the hospital everytime and will save the individual's time and cost. In each house an organism data which is detected from the human body will be transmitted to the distance hospital and will be essentially applied through wireless public data network The medical information transmit system is utilized by wireless close range network It would transmit the obtained organism signal wirelessly from the personal device to the main center system in the hospital. Remote telemetry system is embodied by utilizing wireless media access protocol. The protocol is embodied by grafting CSMA/CA(Carrier Sense Multiple Access with Collision Avoidance) protocol falling mode which is standards from IEEE 802.11. Among the house care telemetry system which could measure blood pressure, pulsation, electrocardiogram, SpO2 the study embodies the ECC(electrocardiograph) measure part. It within the ECC function into the movable device and add 900㎒ band wireless public data interface. Then the aged, the patients even anyone in the house could obtain ECG and keep, record the data. It would be essential to control those who had a health-examination heart diseases or more complicated heart diseases and to observe the latent heart disease patient continuously. To embody the medical information transmit system which is based on wireless network. It would transmit the ECG data among the organism signal data which would be utilized by wireless network modem and NCL(Native Control Language) protocol to contact through wireless network Through the SCR(Standard Context Routing) protocol in the network it will be connected to the wired host computer. The computer will check the recorded individual information and the obtained ECC data then send the correspond examination to the movable device. The study suggests the medical transmit system model utilized by the wireless public data network.

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