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Nitroglycerin-Challenged Tc-99m MIBI Quantitative Gated SPECT to Predict Functional Recovery After Coronary Artery Bypass Surgery (니트로글리세린 투여 Tc-99m-MIBI 정량 게이트 심근SPECT를 이용한 관상동맥우회로술 후 심근 기능 회복 예측)

  • Lee, Dong-Soo;Kim, Yu-Kyeong;Cheon, Gi-Jeong;Paeng, Jin-Chul;Lee, Myoung-Mook;Kim, Ki-Bong;Chung, June-Key;Lee, Myung-Chul
    • The Korean Journal of Nuclear Medicine
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    • v.37 no.5
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    • pp.278-287
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    • 2003
  • Purpose: The performance of nitroglycerin-challenged Tc-99m-MIBI quantitative gated SPECT for the detection of viable myocardium was compared with rest/24-hour redistribution Tl-201 SPECT Materials and Methods: In 22 patients with coronary artery disease, rest Tl-20l/ dipyridamole stress Tc-99m-MIBI gated/24-hour redistribution Tl-201 SPECT were peformed, and gated SPECT was repeated on-site after sublingual administration of nitroglycerin (0.6 mg). Follow-up gated SPECT was done 3 months after coronary artery bypass graft surgery. For 20 segments per patient, perfusion at rest and 24-hour redistribution, and wall motion and thickening at baseline and nitroglycerin-challenged state were quantified. Quantitative viability markers were evaluated and compared;(1) rest thallium uptake, (2) thallium uptake on 24-hour redistribution SPECT, (3) systolic wall thickening at baseline, and (4) systolic wall thickening with nitroglycerin-challenge. Results: Among 100 revascularized dysfunctional segments, wall motion improved in 66 segments (66%) on follow-up gated myocardial SPECT after bypass surgery. On receiver operating characteristic (ROC) curve analysis, the sensitivity and specificity of rest and 24-hour delayed redistribution Tl-201 SPECT were 79%, 44% and 82%, 44%, respectively, at the optimal cutoff value of 50% of Tl-201 uptake. The sensitivity and specificity of systolic wall thickening at baseline and nitroglycerin-challenge were 49%, 50% and 64%, 65% at the optimal cutoff value of 15% of systolic wall thickening. Area under the ROC curve of nitroglycerin-challenged systolic wall thickening was significantly larger than that of baseline systolic wall thickening (p=0.004). Conclusion: Nitroglycerin-challenged quantitative gated Tc-99m-MIBI SPECT was a useful method for predicting functional recovery of dysfunctional myocardium.

STRESS ANALYSIS OF MAXILLARY PREMOLARS WITH COMPOSITE RESIN RESTORATION OF NOTCH-SHAPED CLASSⅤCAVITY AND ACCESS CAVITY ; THREE-DIMENSIONAL FINITE ELEMENT STUDY (쐐기형 5급 와동과 근관와동을 복합레진으로 수복한 상악 소구치에 대한 응력 분석: 3차원 유한요소법적 연구)

  • Lee, Seon-Hwa;Kim, Hyeon-Cheol;Hur, Bock;Kim, Kwang-Hoon;Son, Kwon;Park, Jeong-Kil
    • Restorative Dentistry and Endodontics
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    • v.33 no.6
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    • pp.570-579
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    • 2008
  • The purpose of this study was to investigate the distribution of tensile stress of canal obturated maxillary second premolar with access cavity and notch-shaped class V cavity restored with composite resin using a 3D finite element analysis. The tested groups were classified as 8 situations by only access cavity or access cavity with notch-shaped class V cavity (S or N), loading condition (L1 or L2), and with or without glass ionomer cement base (R1 or R2). A static load of 500 N was applied at buccal and palatal cusps. Notch-shaped cavity and access cavity were filled microhybrid composite resin (Z100) with or without GIC base (Fuji II LC). The tensile stresses presented in the buccal cervical area, palatal cervical area and occlusal surface were analyzed using ANSYS. Tensile stress distributions were similar regardless of base. When the load was applied on the buccal cusp, excessive high tensile stress was concentrated around the loading point and along the central groove of occlusal surface. The tensile stress values of the tooth with class Ⅴ cavity were slightly higher than that of the tooth without class V cavity. When the load was applied the palatal cusp, excessive high tensile stress was concentrated around the loading point and along the central groove of occlusal surface. The tensile stress values of the tooth without class V cavity were slightly higher than that of the tooth with class V cavity.

Analysis of Infiltration Facilities Effects for the Borimcheon Catchment (도림천 유역을 위한 침투증진시설의 효과분석)

  • Lee Seung Jong;Kim Young-Oh;Lee Sang Ho;Lee Kil Seong
    • Proceedings of the Korea Water Resources Association Conference
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    • 2005.05b
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    • pp.100-104
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    • 2005
  • 본 연구에서는 도시의 급격한 발달로 인해 왜곡된 물순환을 나타내고 있는 도림천 유역에 대해서 물순환 회복을 위한 대안 중 침투증진시설의 효과에 대한 모의를 수행하였다. 물순환 모의는 도시유역의 물순환 정량화를 목적으로 개발된 WEP(Water and Energy transfer Processes) 모형을 이용하였으며, 침투증진시설로는 침투트랜치와 투수성 포장재의 설치효과를 분석하였다. 물순환 회복효과는 도시개발 이전의 유출특성과의 비교를 통해 평가하였으며, 이를 위해 1975년의 토지이용도로 도시개발 이전의 물순환 모의를 수행하였다. 모의결과 도시화에 의해 불투수율이 과거보다 $18.7\%$ 증가한 것을 알 수 있었으며, 이로 인해 첨두시간은 감소하고, 첨두 및 총유출량은 증가한 것으로 나타났으며, 침투량과 기저유출량이 감소한 것을 확인할 수 있었다. 침투증진시설의 설치효과는 침투트랜치와 투수성 포장재의 개별적인 설치보다는 두 가지를 함께 적용했을 경우에 도시개발 이전의 유출특성에 근접하는 것을 알 수 있었다.

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Design and Performance Evaluation of OBP Satellite B-ISDN Transport Network Multiple Access Method (OBP 탑재 위성 B-ISDN 중계망 다중 접속 방식 설계 및 평가)

  • Park, Seok-Cheon;Lee, Gwang-Bae
    • The KIPS Transactions:PartC
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    • v.8C no.2
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    • pp.198-206
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    • 2001
  • · 21세기 도고 정보화 사회에서의 위성통신은 현존 위성 시스템에서 주로 제공하는 국가간 장 거리 전화, 방송 중계 서비스 등을 포함한 광범위한 대용량 디지털 멀티미디어 서비스 형태 의 트래픽을 처리하여 재분배하는 고성능, 다기능 정보통신으로 발전하고 있다. 이에 따라 전세계적으로 위성 수의 증가에 따른 위성궤도 부족과 주파수 자원의 고갈 등의 문제점을 야기시키게 되었다. 이를 해결하기 위해서는 기존의 단순 중계기의 역할뿐만 아니라, 위성탑 재 IF/RF 스위칭 기술, 기저대역 신호처리 기술, 다중 빔 안테나 기술 등을 포함한 OBP 탑 재 위성 시스템이 필요하게 된다. 따라서 본 논문에서는 기본적으로 멀티미디어 서비스를 제공하고 주파수 재사용 기법을 적용한 다중 스폿 빔을 송수신하는 차세대 OBP 탑재 위성 B-ISDN 중계망 접속 방식을 설계하고, 설계된 위성 B-ISDN 중계망 다중 접속 방식의 성 능을 평가하였다.

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Construction of Multirate Multiplexing Transceiver System using Wavelet Packet - Based filter Bank (Wavelet 패킷 기저 필터 뱅크를 이용한 Multirate 다중화 송수신 시스템 구성)

  • 장문섭;이정재
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 1998.11a
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    • pp.549-552
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    • 1998
  • 본 논문에서는 wavelet 패킷의 직교성을 이용한 새로운 다중 통신 시스템을 구성하고 그 특성을 분석하였다. 유한에너지 신호공간 L$^2$(R)로부터 부분공간으로 신호를 분해할 수 있는 MRA(Multiresolution Analysis)의 기본개념과 이를 이용한 wavelet와 QMF(Quadrature Mirror Filter)와의 관계를 검토하였다. MRA의 개념을 보다 일반화한 신호의 wavelet 패킷 변환과 역변환을 실현하기 위한 알고리즘을 고찰하고 MRF(Multirate Filter Bank)를 이용하여 다중화 시스템을 설계하였다. 제안된 시스템은 구성이 간단하며 최대 이용자의 수와 정보 데이터의 전송율에 대한 유연성을 기대할 수 있음을 보였다.

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A D-H type Public Key Distribution System using a Normal Basis in GF($2^m$) (GF($2^m$/)의 정규기저를 사용한 D-H 형 공용키이분배 시스템)

  • 이창순;문상재
    • Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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    • 1991.11a
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    • pp.49-57
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    • 1991
  • Several variants of the Diffie-Hellman public key distribution are examined, and a simple and relatively secure public key distribution protocol is introduced. Using a normal basis of GF(2$^{m}$ ), this protocol is implemented, and simulated in software. A program is developed, whereby a normal basis is effectively searched for fast multiplication in GF(2$^{m}$ ).

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A Case Report : Hypersexuality and Obsessive-Compulsive Behaviors in a Stroke Patient with the Left Mesial Frontal Cortex and Both Basal Ganglia Lesion (좌측 정중 전두엽과 양측 기저절 경색 후 과잉성욕 증상과 강박 증상을 보인 환자 1례)

  • Kim, Se Joo;Kim, Young Shin;Choi, Nak Kyung;Lee, Byung-Chul;Lee, Man Hong
    • Korean Journal of Biological Psychiatry
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    • v.8 no.2
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    • pp.271-275
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    • 2001
  • Hyposexuality after stroke has been frequently observed, but hypersexuality as a sequela of stroke has not been commonly documented. We report a patient who exhibited hypersexuality and obsessive-compulsive behaviors after stroke in the region of the left mesial frontal cortex and both basal ganglia. At 2 months after stroke, he visited psychiatric unit due to these symptoms. His motor function was almost full recovered. He was treated with fluvoxamine and perphenazine. With two-month medication, his hypersexuality and obsessive-compulsive behavior disappeared. This case may indicate that basal ganglia-thalamocortical circuit plays an important role in the mediation of sexual behavior and obsessive-compulsive behavior. Since changes in sexual activity may not be spontaneously reported, a systemic inquiry into patient's sexual functioning after infarction in frontal lobe or basal ganglia is warranted.

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Estimation of Baseflow based on Master Recession Curves (MRCs) Considering Seasonality and Flow Condition (계절·유황특성을 고려한 주지하수감수곡선을 활용한 기저유출분리 평가)

  • Yang, Dongseok;Lee, Seoro;Lee, Gwanjae;Kim, Jonggun;Lim, Kyoung Jae;Kim, Ki-Sung
    • Journal of Wetlands Research
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    • v.21 no.1
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    • pp.34-42
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    • 2019
  • Baseflow which is one of the unmeasurable components of streamflow and slowly flows through underground is important for water resource management. Despite various separation methods from researches preceded, it is difficult to find a significant separation method for baseflow separation. This study applied the MRC method and developed the improved approach to separate baseflow from total streamflow hydrograph. Previous researchers utilized the whole streamflow data of study period at once to derive synthetic MRCs causing unreliable results. This study has been proceeded with total nine areas with gauging stations. Each three areas are selected from 3 domestic major watersheds. Tool for drawing MRC had been used to draw MRCs of each area. First, synthetic MRC for whole period and two other MRCs were drawn following two different criteria. Two criteria were set by different conditions, one is flow condition and the other is seasonality. The whole streamflow was classified according to seasonality and flow conditions, and MRCs had been drawn with a specialized program. The MRCs for flow conditions had low R2 and similar trend to recession segments. On the other hand, the seasonal MRCs were eligible for the baseflow separation that properly reflects the seasonal variability of baseflow. Comparing two methods of assuming MRC for baseflow separation, seasonal MRC was more effective for relieving overestimating tendency of synthetic MRC. Flow condition MRCs had a large distribution of the flow and this means accurate MRC could not be found. Baseflow separation using seasonal MRC is showing more reliability than the other one, however if certain technique added up to the flow condition MRC method to stabilize distribution of the streamflow, the flow conditions method could secure reliability as much as seasonal MRC method.

Histologic findings of three-wall intrabony defects around dental implants using different grafting materials in beagle dogs (수종의 골이식재를 이용한 성견의 임플란트 주위 3면 골내낭의 조직학적 관찰)

  • Moon, Hee-Il;Moon, Sang-Kwon;Shim, Chang-sung;Shim, Jung-Sung;Lee, Yong-Keun;Cho, Kyu-Sung
    • Journal of Periodontal and Implant Science
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    • v.33 no.3
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    • pp.439-455
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    • 2003
  • 연구목적 : SLA surface dental implant 주위의 3면 골내낭에서 xenogeneic demineralized bone matric putty, porous ${\beta}$-tri-calcium phosphate, 새로이 개발된 non-crystalline calcium phosphate glass를 사용한 치료를 조직학적으로 비교 평가하기 위한 것이다. 연구방법 : 실험동물로는 15개월에서 18개월 사이의 12kg에서 15kg 정도되는 성견을 사용하였다. 20개의 SLA surface implant가 사용되었으며, 성견 하악의 양측에 각각 2개씩 사용되었다. 임플란트 식립전에, 각각의 임플란트 근심면에 straight fissure bur를 이용하여 표준화된 3면 골내앙(근원심 5mm ${\times}$협설 3mm ${\times}$깊이 3mm)을 형성하였다. 형성된 골 결손부에는 demineralized bone matrix putty, porous ${\beta}$-tri-calcium phosphate, non-crystalline calcium phosphate glass를 넣은 것을 각각 실험군으로, 이식재를 넣지 않은 것을 대조군으로 사용하였다. 8주 후에 실험 동물을 희생시키고 조직학적 관찰을 하였다. 결과 : 조직학적 소견상 임플란트 주위에 급성 염증 소견은 보이지 않았으며, non-crystalline calcium phosphate glass은 매우 적은량의 신생골을, ${\beta}$-TCP을 이용한 골내낭에서는 약간의 기저부에서 유래된 신생골이 관찰된다. ${\beta}$-TCP granules 가운데로 상당량의 측면의 골에서 유래된 신생골 형성이 보인다. xenogeneic DBM putty에서는 많은 량의 신생골이 기저부에 형성된 것을 볼수 있으나 대조군과의 차이는 크지 않다. 이식재의 종류와 상관없이 흡수되지 않은 이식재를 임플란트 주위에서 관찰할 수 있었다. 골내낭 안의 이식재들은 모두 connective tissue로 둘러 싸여 있었다. 모든 실험군에서 이식재에서 기인한 신생골 형성과 임플란트 표면에 신생 골유착의 조직학적 증거는 발견되지 않았다.

A Study on Scattering Center Extraction Using Full Polarimetric Data (다중편파 데이터를 이용한 표적 산란점 추출에 대한 연구)

  • Jeong, Seong-Jae;Lee, Seung-Jae;Kim, Kyung-Tae
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.27 no.5
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    • pp.463-470
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    • 2016
  • In this paper, we introduce a method of scattering centers extraction using the polarimetric data. VIRAF software based on the PO (Physical Optics) and PTD(Physical Theory of Diffraction) were used to calculate the surface scattering and the edge or wedge scattering, respectively. In addition, by using the unitary transformation, 4-channel data based on the linear polarization basis were converted to 2-channel data based on the left/vertical-circular polarization basis, leading to data compression coherently. The scattering mechanism was analyzed in terms of the polarization states and different look angles by using the scattering center of a target extracted by the 2D RELAX algorithm.