• KSBB Journal
• /
• v.18 no.4
• /
• pp.335-339
• /
• 2003

This research was concentrated to Investigate the effects of Insumon as a newly developed dietary supplement in patients with type 2 diabetes. The average glycated hemoglobin level was dropped from 7.0${\pm}$1.1％ to 6.7${\pm}$0.9％ after 8 weeks with statistic significance (p＝0.0202). For patients of HbA1c over 7％, the average HbA1c significantly decreased from 8.1${\pm}$0.8％ to 7.5${\pm}$0.8％ (p＝0.0171). The average fasting blood glucose level was decreased significantly from 9.5${\pm}$1.2 mmol/L (171.6${\pm}$22.3 mg/dL) to 8.5${\pm}$1.5 mmol/L (152.3${\pm}$26.3 mg/dL) (p=0.0262) after 4 weeks and to 8.8${\pm}$1.5 mmol/L (158.3${\pm}$24.1 mg/dL) (p=0.0445) after 8 weeks in the group of patients of FBG of over 7.8 mmol/L (140 mg/dL). The average HDL cholesterol level was increased significantly after 8 weeks from 1.2${\pm}$0.2 mmol/L (46.5${\pm}$8.6 mg/dL) to 1.3${\pm}$0.3 mmol/L (51.6${\pm}$10.9 mg/dL) (p=0.0007). Thus, these results suggested that patients with type 2 diabetes might benefit by Insumon as a herbal dietary supplement without any serious side effects.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2016.05a
• /
• pp.281-281
• /
• 2016

기후변화로 인한 기상학적 자연재해로부터 대비하고 안정적인 용수공급을 위해 유역의 다양한 수문 요소들에 대한 분석 필요성이 증가하고 있다. 계절적 강수량의 편차가 큰 우리나라는 유역 통합 물관리가 중요하며, 효율적 수자원 관리와 물안보 확보를 위해 유역내 물순환을 이해하는 것이 중요하다. 유역의 유출을 결정하는 요소들에는 강우, 증발산량, 토양 수분 및 지하수 등이 있으며, 시간적으로는 홍수와 같이 단기에 발생하는 유출과 장기적으로 발생하는 유출이 있다. 장기 유출은 단기 유출에 비해 토양내 수분량이 무시할 수 없을 정도로 영향을 미치게 되므로, 1년 이상의 장기 유출 해석을 위해서는 강우가 발생하지 않는 기간 동안의 토양 수분량 변화와 증발산 영향을 고려할 필요가 있다. K-water에서 자체 개발된 분포형 장단기유출 모델인 K-DRUM은 유역을 격자(grid)단위로 구분하고 각 셀들에 대한 매개변수는 흐름방향도, 표고분포도, 토지이용도, 토지피복도 등을 GIS처리하여 일괄 입력할 수 있도록 함으로써 매개변수 산정과정에서 문제가 되는 경험적인 요인을 제거하였다. 흐름의 구분은 얕은면 흐름, 지표하 흐름, 지하수 흐름으로 구분하여 운동파법과 선형저류법을 적용하였다. 또한 초기 토양함수 자동보정기법으로 실제의 기저유출량을 재현하여 전체적인 유출모의 정확도를 높였으며, FAO-56 Penman-Monteith법을 적용한 증발산량 산정모듈과 Sugawara et al.(1984)이 제안한 개념적 융설 및 적설모듈을 추가하였다. K-DRUM모형을 이용한 유출분석은 용담댐 시험유역을 대상으로 2013년도 1년간의 유출모의를 수행하였다. 입력자료는 용담댐 유역의 지형, 토양 및 토지특성 정보와 시단위 강우 및 기상정보(온도, 바람, 일사 등)를 활용하였다. 분석 결과, 총 관측유출량은 7,151 ㎥/s이고 총 계산유출량 $8,257m^3/s$이며, 관측유출량 대비 계산유출량은 약 115% 정도로 나타났다. 연간 총 강우량은 1303.5 mm로 유역면적 약 $930km^2$을 적용하여 유역 총 강우량을 산정하면 $14,030m^3/s$로서 관측유출량은 유역 총 강우량 대비 51%이고 계산유출량은 59% 정도로 나타났다. 즉 유역 유출율은 약 51% 수준으로 보통의 유역과 유사한 수준이다. 관측된 토양수분량과 K-DRUM 모형의 계산된 토양수분량을 비교하기 위하여 관측 토양수분량의 비율을 이용하여 비교하였다. 모의결과 토양수분은 강우에 의해 변화하며, 관측결과와 유사한 형태로 나타남을 알 수 있었다.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.2
• /
• pp.404-411
• /
• 2019

In this study, the HEC-HMS was applied to determine rainfall-runoff processes for the Gokgyuchun basin. Several sub-basins have large-scale reservoirs for agricultural needs and they store large amounts of initial runoff. Three infiltration methods were implemented to reflect the effect of initial loss by reservoirs: 'SCS-CN'(Scheme I), 'SCS-CN' with simple surface method(Scheme II), and 'Initial and Constant rate'(Scheme III). Modeling processes include incorporating three different methods for loss due to infiltration, Clark's UH model for transformation, exponential recession model for baseflow, and Muskingum model for channel routing. The parameters were calibrated using an optimization technique with trial and error method. Performance measures, such as NSE, RAR, and PBIAS, were adopted to aid in the calibration processes. The model performance for those methods was evaluated at Gangcheong station, which is the outlet of study site. Good accuracy in predicting runoff volume and peak flow, and peak time was obtained using the Scheme II and III, considering the initial loss, whereas Scheme I showed low reliability for storms. Scheme III did not show good matches between observed and simulated values for storms with multi peaks. Conclusively, Scheme II provided better results for both single and multi-peak storms. The results of this study can provide a useful tool for decision makers to determine master plans for regional flood control management.

• Korean Journal of Clinical Laboratory Science
• /
• v.53 no.3
• /
• pp.208-216
• /
• 2021

Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study aimed to investigate the status of renal function in patients with COVID-19. The study surveyed a total of 649 patients hospitalized with COVID-19 at a hospital located in southern Gyeonggi Province, South Korea over a one month period in January 2021. The parameters analyzed were blood urea nitrogen (BUN), creatinine, sodium, potassium, chloride, and estimated glomerular filtration rate (eGFR). The BUN and creatinine of the COVID-19 patients were found to be higher than the normal reference range, specially in males, and in the elderly (60s and 80s or older). The serum electrolyte levels of the patients were observed to be within the reference intervals. Of the subjects, males over 80 years of age had a Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) of 60 mL/min/1.73 m² or less. Recent research suggests that some severe cases of COVID-19 are showing signs of kidney damage, even in those with no prior underlying kidney disease. Thus, assessment of kidney function using multiple indicators could help diagnose abnormal renal function in patients with COVID-19.

• Journal of the Korean Crystal Growth and Crystal Technology
• /
• v.31 no.1
• /
• pp.24-31
• /
• 2021

We report structural, mechanical, and thermal properties of diecast ADC12 aluminum alloys characterized using synchrotron X-ray diffraction (XRD), scanning electron microscopy, energy dispersive X-ray (EDX) analysis, thermal conductivity (λ), Vickers hardness (Hv), and stress-strain measurements. We also studied the effect of post-annealing performed in a vacuum atmosphere on the mechanical properties of diecast ADC12 alloys. EDX and XRD results revealed that Al2Cu and AlCu3 grains are formed, well dispersed in Al base and highly crystalline. Ultimate tensile strength (UTS) of 307.9 ± 9.1 MPa and elongation of 2.98 ± 0.62 % were estimated. λ was 129.3 ± 0.27 W/m·K and Hv was approximately 130. Both values were significantly higher than the reported values. At annealing temperatures ranging from 25 to 200℃, UTS and Hv values remained constant, while as the annealing temperature increased to 500℃, these values gradually decreased. This is because stabilization of the microstructure improves toughness and ductility.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.21 no.3
• /
• pp.62-72
• /
• 2022

In this study, a miniaturized GPS band(L₁ : 1.575 GHz) antenna that can be mounted on a small drone is proposed. The miniaturization was designed by applying the perturbation method based on the λ/4 microstrip antenna and lengthening the current path at the edge of the patch. The miniaturized antenna was fabricatred such that it could be attached to the surface of styrofoam(ε_r=1.06, t=10 mm) having a size of 10 mm × 9 mm × 10 mm (0.05 λ × 0.05 λ × 0.05 λ). The thickness and length of the feeding line and the spacing between short stubs were adjusted for impedance matching. S₁₁ was found to be -18.8 dB at the center frequency of the fabricated antenna, 1.575 GHz. The radiation pattern measurement results show that the maximum gain of E_θ is 1.87 dBi in 0 directions in the xz-plane, and that E_θ is an omnidirectional characteristic with an average gain of -1.7 dBi in the yz-plane. It was found that the antenna can be used as an ultra-small microstrip antenna, which can be mounted on a small dron for GPS, and is capable of preserving a reduction ratio of 98.8% as compared to a λ/2 microstrip patch antenna.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.31 no.2
• /
• pp.186-194
• /
• 1986

In an attempt to find better ways to relate growth with temperature and to estimate maturity differences in corn (Zea mays L.), various formulas of computing Growing Degree Days (GDD) were evaluated. Utilizing data from 17 plantings of a single cross, Suweon 19, over a 3 year period, 24 different methods of computing GDD were compared for their ability to reduce variations over different plantings. The best equation was to compute GDD with a base temperature of 10$^{\circ}C$ and an optimum of 30$^{\circ}C$. The excess temperature above 30$^{\circ}C$ was subtracted to account for high temperature stress. GDDs required for emergence and silking of Suweon 19 were 64${\pm}$12$^{\circ}$ and 794${\pm}$19$^{\circ}$, respectively. Based on these GDD values, emergence and silking dates could be estimated with a variation less than 3 days. The observed and estimated number of days from planting to emergence and silking were not significantly different.

• Clinical and Experimental Reproductive Medicine
• /
• v.36 no.2
• /
• pp.111-119
• /
• 2009

Objective: The aim of this study was to compare the clinical efficacy of clomiphene citrate (CC) and letrozole combined with gonadotropins for controlled ovarian stimulation (COS) in patients with CC-induced thin endometrium Methods: Fifty-one intrauterine insemination cycles performed in patients who previously had a thin endometrium (<8 mm) to ovulation induction using CC were included in this study. A CC 100 mg/day (CC+gonadotropin group, n=26) or letrozole 2.5 or 5 mg/day (letrozole+gonadotropin group, n=25) was administered on day 3~7 of the menstrual cycle, combined with gonadotropins at dose 75~150 IU every other day starting on day 5~7. We compared total dose of gonadotropin used, endometrial thickness, endometrial pattern, number of follicles ${\geq}14\;mm$ on hCG day, pregnancy rate and multiple pregnancy rate between the two groups, which were statistically analyzed using Mann-Whitney U test or Fisher's exact test, where appropriate. Results: There were no significant differences in clinical characteristics such as age, duration of infertility, number of previous IUI cycles, basal serum hormone levels and cause of infertility between the two groups. In both groups, the endometrium was significantly thicker than that of previous ovulation induction cycles using CC. No significant differences were found in the total dose of gonadotropin used, day of hCG administration, the rate of triple endometrium and pregnancy rate. The number of follicles ${\geq}14\;mm$ was significantly lower ($3.7{\pm}1.7$ vs. $2.8{\pm}1.7$, p=0.03) and the endometrium on hCG day was significantly thicker ($7.7{\pm}1.5$ vs. $9.1{\pm}1.7$, p=0.001) in letrozole+gonadotropin group compared to CC+gonadotropin group. Conclusion: The clomiphene citrate and letrozole combined with gonadotropins appear to avoid the undesirable effects on the endometrium frequently seen with CC for ovulation induction. However, in terms of adequate endometrial development or optimal follicular growth, letrozole may be more beneficial than CC for gonadotropin-combined COS in patients with CC-induced thin endometrium. Further prospective randomized controlled studies in a larger scale will be necessary to confirm our findings.

• Clinical and Experimental Pediatrics
• /
• v.50 no.11
• /
• pp.1085-1090
• /
• 2007

Purpose : Radiofrequency catheter ablation (RFCA) has become an effective therapeutic modality for treating pediatric tachyarrhythmias. Using conventional RFCA catheters, ablation of parahisian accessory pathways may be difficult and have high risk for heart block. We reviewed the efficacy and complications of the RFCA in children and adolescent with arrhythmias including parahisian accessory pathways. Methods : We studied 48 patients (aged 2 years to 20 years) who had undergone RFCA from August 2003 to March 2007. We reviewed clinical findings, electrophysiologic studies, RFCA data, complications, and follow-up results of the patients. Results : Mean age of the patients was 13.1 years. Numbers and types of arrhythmias (age, acute success rate) were as follows: 19 WPW syndrome including 5 parahisian accessory pathways ($13.7{\pm}4.6yr$, 18/19), 11 atrioventricular reentrant tachycardia with concealed bypass tract ($12.3{\pm}5.0yr$, 10/11), 13 atrioventricular nodal reentrant tachycardia ($12.6{\pm}4.4yr$, 13/13), 4 atrial flutter ($13.0{\pm}7.4yr$, 3/4), and 1 ventricular tachycardia (20 yr, 1/1). Associated cardiac structural lesion was not detected in 48 patients. The recurrence rate was 6.5%, and the final success rate was 93.8%. Conclusion : These results suggest that RFCA is a highly effective treatment method in children and adolescent with tachyarrhythmia.

• The Korean Journal of Nuclear Medicine
• /
• v.39 no.6
• /
• pp.438-444
• /
• 2005

Purpose: Anhedonia has been proposed to be the result of a basic neurophysiologic dysfunction and a vulnerability marker that precede and contribute to the liability of developing schizophrenia. We hypothesized that anhedonia, as a construct reflecting the decreased capacity to experience pleasure, should be associated with decreased positive hedonic affect trait. This study examined the relationship between anhedonia and positive hedonic affect trait and searched for the brain legions which correlate with anhedonia in normal subjects. Materials and Methods: Using $^{18}F$-FDG PET scan, we investigated the brain activity of twenty one subjects during resting state. Questionnaires were administrated after the scan in order to assess the self-rated individual differences in physical/social anhedonia and positive/negative affect traits. Results: Negative correlation between physical anhedonia score and positive affect trait score was significant (Pearson coefficient =-0.440, p<0.05). The subjects physical and social anhedonia scores showed positive correlation with metabolic rates in the cerebellum and negative correlation with metabolic rates in the inferior temporal gyrus and middie frontal gyrus. In addition, the positive affect trait score positively correlated with various areas, most prominent with the inferior temporal gyrus. Conclusion: These results suggest that neural substrates, such as the inferior temporal gyrus and prefrontal-cerebellar circuit, which dysfunction has been proposed to be involved with the cognitive deficits of schizophrenia, may also play a significant role in the liability of affective deficits like anhedonia.