• Korean Journal of Transplantation
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• v.28 no.3
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• pp.135-143
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• 2014

Background: Kidney injury molecule-1 (KIM-1) is known as a good ancillary marker of acute kidney injury (AKI) and its expression has also been observed in acute rejection and chronic graft dysfunction. We tested usefulness of KIM-1 as an indicator of acute and chronic renal graft injury by correlating KIM-1 expression with renal graft function and histology. Methods: A total of 133 zero-time biopsies and 42 follow-up biopsies obtained within 1 year posttransplantation were selected. Renal tubular KIM-1 staining was graded semiquantitatively from 0 to 3 and the extent of staining was expressed as the ratio of KIM-1 positive/CD10 positive proximal tubules using Image J program. Results: KIM-1 was positive in 39.8% of zero-time biopsies. KIM-1 positive cases were predominantly male and had received grafts from donors with older age, deceased donors, and poor renal function at the time of donation, compared with KIM-1 negative cases. KIM-1 expression showed correlation with delayed graft function and acute tubular necrosis. In comparison of KIM-1 expression between stable grafts (n=23) and grafts with dysfunction (n=19) at the time of repeated biopsy, the intensity/extent of KIM-1 staining and renal histology at zero-time did not differ significantly between the two groups. Histologically, KIM-1 expression was significantly increased with both acute and chronic changes of glomeruli, tubules and interstitium, peritubular capillaritis, and arteriolar hyalinosis. Conclusions: KIM-1 can be used as an ancillary marker of AKI and a nonspecific indicator of acute inflammation and tubulointerstitial fibrosis. However, KIM-1 expression at zero-time is not suitable for prediction of long-term graft dysfunction.

• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.1
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• pp.85-97
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• 2023

Seoul Boramae Park was opened on May 5, 1986, after the Republic of Korea Air Force Academy relocated to Cheongju City in 1985. This study aims to examine the birth and evolution of Seoul Boramae Park and diagnose the park's value being transformed from the former site of the Air Force Academy. Policy reports and newspaper data were analyzed as a research method, focusing on Seoul public records. The study results are as follows. First, Seoul Boramae Park is a large-scale park created before the policy for parks on relocated sites we enacted. Second, Seoul Boramae Park has historical value as an urban park where memories and traces of the Air Force Academy overlap. Third, Seou Boramae Park contributed to regional change by promoting the public value of parks created on the relocated sites with an urban planning method. Seoul Boramae Park has implications for Korean landscape history as a case of securing large green areas in Seoul and presenting its function and roles as a park created on a relocated site.

• Journal of the Korea Society for Simulation
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• v.32 no.1
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• pp.1-11
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• 2023

Smart factory environments and digital twin environments are established, and today's factories accumulate vast amounts of production data and are managed in real time as visualized results suitable for user convenience. Production simulation techniques are in the spotlight as a way to prevent delays in delivery and predict factory volatility in situations where production schedule planning becomes difficult due to the diversification of production products. With the development of the digital twin environment, new packages are developed and functions of existing packages are updated, making it difficult for users to make decisions on which packages to use to develop simulations. Therefore, in this study, the concept of Discrete Event Simulation (DES) performed based on discrete events is defined, and the characteristics of various simulation packages were compared and analyzed. To this end, studies that solved real problems using discrete event simulation software for 10 years were analyzed, and three types of software used by the majority were identified. In addition, each package was classified by simulation technique, type of industry, subject of simulation, country of use, etc., and analysis results on the characteristics and usage of DES software were provided. The results of this study provide a basis for selection to companies and users who have difficulty in selecting discrete event simulation package in the future, and it is judged that they will be used as basic data.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.3
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• pp.477-496
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• 2017

A drastic development of modern cities and transportation means as part of a rapid industrialization and urbanization for the past half-century has consistently broaden the boundaries of urban dwellers while, at the same time, raising issues as to establishing relationships among them throughout the society following the materialization of modern urban planning. Within the framework of the postmodern concept, there have been consistent efforts to create a community space in appropriate size and, in particular, the concept of New Urbanism and Urban Village that emerged in mid 1800s along with the effort to build a community by building an ideal city provides an important meaning today when people are seeking to restore a healthy community. Against this backdrop, this study aims to explore the concept of community and to determine its optimal scope of implementation in the sense of healing environment under the premise that organizing a healthy city is based on building a solid urban community. The study findings and conclusions are as follows. First, a community is a subject of constant consideration in the process of historical development of the city and has required us to take a variety of strategic approaches and to determine the scope of implementation. Second, the activities of a healthy community have been conducted under various types of environments, including churches, commercial facilities, urban plazas, parks, and streets in various scales, reflecting their unique characteristics. Third, in the process of designing a healthy and sustainable city, determination of location carries significant implications along with building a community of appropriate size, which requires multidisciplinary considerations in addition to functional approaches. Fourth, the composition and design of a modern urban community need to seek practical ways of its implementation within the concept of healing environment.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.7-8
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• 2020

지속가능한 국가 발전을 위한 물관리 정책은 항상 국정 과제의 중심에 있다. 물관리는 수재해예방, 양질의 안정된 물이용, 충분한 식량생산, 수생태계와 물환경의 보호, 효과적 재정투자 등과 같이 다양한 분야에 계층적이면서도 상호연계성 있는 전문성을 요구한다. 동시에 물관리의 효과와 편익은 경제활동의 기반이 되고 환경보전의 원천이므로 정책의 수요는 정부뿐만 아니라 국민과 더불어 자연으로부터 기인한다. 특히 기후변화의 불확실성 또는 감염병 대발생과 국가적 위기에도 지속가능한 국가 발전을 이행하기 위해서는 시의성 있고 유효한 물관리 정책은 필수이다. 그동안 우리나라 물관리 정책의 세분화 또는 파편화는 물관리 전문성 강화의 효과보다는 비효율성의 결과를 더 크게 생산해 왔었다. 특히 부족한 협력과 조정은 과잉·중복 투자, 비일관적 정책, 비효율적 성과라는 왜곡된 통합물관리 정책 순환이 반복되게 하였다. 최근 정부는 국토교통부의 하천수량(홍수 포함) 및 광역상수도 관리 기능을 환경부로 이관하는 물관리일원화를 추진하여 통합물관리의 발판을 마련하는 계기를 달성하였다. 하지만 비록 정부조직법 개정과 물관리기본법 제정으로 통합물관리 정책의 틀은 마련되었으나, 국토교통부가 하천법 상의 일부 사무를 담당하므로서 하천관리 정책의 복잡성과 다원화는 높아졌다. 따라서 하천의 이용 및 관리에 관한 만족도, 관리주체, 미래상, 물관리일원화 후 정책수요, 기후변화에 관한 인식, 하천관리 참여 의향 등을 조사하는 연구는 시급한 실정이며 향후 하천기본계획, 생태하천복원사업, 소하천정비사업 등과 같은 재정사업의 추진 방향에도 매우 중요한 주제라고 할 수 있다. 본 연구에서는 현재와 미래 하천의 이용 및 관리, 그리고 정책방향에 대하여 일반 시민(4,500명)과 전문가(168명) 대상의 설문조사를 실시하였으며 인식의 공통점과 차이를 비교분석하였다. 설문조사의 내용은 3가지 부문(하천이용, 하천관리, 하천정책)으로 구분하여 각 부문별로 세부문항으로 구성하였다. 일반 시민과 전문가 간의 인식조사 비교 결과, 공통적으로 시민과 전문가는 하천의 바람직한 미래상으로 '깨끗한 수질의 하천'을 가장 높게 선호하였다. 하천관리 우선순위를 묻는 질문에 대한 시민과 전문가의 응답도 대하천, 도랑이나 개울, 중하천, 소하천 순으로 동일하였지만, 1순위와 2순위의 격차는 시민(26.1%)보다 전문가(1.2%)가 낮았다. 또한 시민과 전문가는 하천관리의 주체로 '물전문기관'을 가장 높게 선호하였지만, 전문가는 '물전문기관' 다음으로 중앙부처(20.2%)를 선호하였지만, 시민은 중앙부처(6.8%)를 가장 선호하지 않는 하천관리 주체로 응답하여 두 집단 간의 큰 인식의 차이를 알 수 있었다. 물관리일원화 후 보다 큰 관심을 가져야할 정책으로는 '건강하고 깨끗한 수질'을 시민(38.9%)과 전문가(47.0%)는 1순위로 선택하였으나, 2순위는 시민은 '생태서식공간'(11.6%)을 전문가는 '안정적 수량확보'(20.2%)를 선택하여 두 집단의 인식 차이가 있음을 알 수 있었다.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.3
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• pp.245-256
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• 2023

When restoring with a dental digital system for implant-supported prosthesis, a double digital scanning technique is required: an intraoral scan of the three-dimensional implant location and intraoral scan after placement of temporary denture or provisional prosthesis. During the intraoral scan, the use of scan body as a stable landmark can improve the accuracy of digital impression and simplify laboratory process. In this case, a full-digital system was used to plan and fabricate a custom abutment, provisional prosthesis, and definitive prosthesis. After implant placement, the scan area of the intraoral scan body connected with implant and the intraoral scan body marked on the inside of temporary denture were superimposed. Out of the superimposed files, a custom abutment and provisional prosthesis were fabricated which match the vertical dimension of temporary denture, and definitive prosthesis was fabricated based on provisional prosthesis. We report this case because result has been functionally and esthetically satisfactory by using vertical dimension and central relation set during the fabrication of temporary denture to the definitive prosthesis.

• Journal of the Korea Knowledge Information Technology Society
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• v.13 no.5
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• pp.607-614
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• 2018

Oryeong-san is a prescription widely used for diseases where water is stagnant because it has the effect of circulating the water in the body and releasing it into the urine. In order to investigate the mechanisms of oryeong-san, we in this paper construct and analysis the compound-target network of medicinal materials constituting oryeong-san based on a systems pharmacology approach. First, the targets related to the 475 chemical compounds of oryeong-san were searched in the STITCH database, and the search results for the interactions between compounds and targets were downloaded as XML files. The compound-target network of oryeong-san is visualized and explored using Gephi 0.8.2, which is an open-source software for graphs and networks. In the network, nodes are compounds and targets, and edges are interactions between the nodes. The edge is weighted according to the reliability of the interaction. In order to analysis the compound-target network, it is clustered using MCL algorithm, which is able to cluster the weighted network. A total of 130 clusters were created, and the number of nodes in the cluster with the largest number of nodes was 32. In the clustered network, it was revealed that the active compounds of medicinal materials were associated with the targets for regulating the blood pressure in the kidney. In the future, we will clarify the mechanisms of oryeong-san by linking the information on disease databases and the network of this research.

• Korean Journal of Ecology and Environment
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• v.56 no.4
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• pp.330-338
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• 2023

To investigate the impact of forestry projects on the carbon stocks of forests, we estimated the carbon stock change of above-ground and soil before and after forestry projects using forest type maps, forestry project information, and soil information. First, we selected six map sheet with large areas and declining age class based on forest type map information. Then, we collected data such as forest type maps, growth coefficients, soil organic matter content, and soil bulk density of the estimated areas to calculate forest carbon storage. As a result, forest carbon stocks decreased by about 34.1~70.0% after forestry projects at all sites. In addition, compared to reference studies, domestic forest soils store less carbon than the above-ground, so it is judged that domestic forest soils have great potential to store more carbon and strategies to increase carbon storage are needed. It was estimated that the amount of carbon stored before forestry projects is about 1.5 times more than after forestry projects. The study estimated that it takes about 27 years for forests to recover to their pre-thinning carbon stocks following forestry projects. Since it takes a long time for forests to recover to their original carbon stocks once their carbon stocks are reduced by physical damage, it is necessary to plan to preserve them as much as possible, especially for highly conservative forests, so that they can maintain their carbon storage function.

• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.5
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• pp.737-746
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• 2023

As the core infrastructure to lead technical innovation for the fourth industrial revolution, economic value and utilizations of radiowaves are increased rapidly. The objectives of this study are to recognize the growing trend of radio stations that transmit information using radiowaves, a limited resource of the country, and to propose developed plans for the radio stations operation system in line with the changing radio technology and use environment. To be specific, the detailed implementation procedures and methods of the system were derived in accordance with the government's plan to convert the complete inspection of radio stations into a SDoC(Self Declaration of Conformity) by the telco. SDoC is a policy that grants autonomy and responsibility for radio waves interference management to existing telecom operator recognized as having radio stations operating capabilities. It has significance in that the function of radio stations inspection, which is a representative technical regulation, is efficiently distributed to the government and the private sector. This study has significance in providing reference for expediting deregulation in the radiowaves management policy.

• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.5
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• pp.70-83
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• 2023

Recently, the Korea Forest Service has implemented a planning project about wind corridor forests as a response measure to climate change. Based on this, research on wind corridors has been underway. For the creation of wind corridor forests, a preliminary evaluation of the wind corridor function is necessary. However, currently, there is no evaluation index to directly evaluate and spatially distinguish the types of wind corridors, and analysis is being performed based on indirect indicators. Therefore, this study proposed a method to evaluate and classify wind corridors by utilizing heat deficit analysis as an evaluation index for cold air generation. Heat deficit was analyzed using a cold air analysis model called Kaltluftabflussmodell_21 (KLAM_21). According to the results of the simulation analysis, the wind path was functionally classified. The top 5% were classified as cold-air generating Areas (CGA), and the bottom 5% as cold-air vulnerable Areas (CVA). In addition, the cold-air flowing Areas (CFA) were classified by identifying the flow of cold air moving from the cold air generation area. It is expected that the methodology of this study can be utilized as an evaluation method for the effectiveness of wind corridors. It is also anticipated to be used as an evaluation index to be presented in the selection of wind corridor forest sites.