• Clinical and Experimental Pediatrics
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• v.45 no.10
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• pp.1227-1233
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• 2002

Purpose : Several studies have shown that increases of eosinophil markers are common findings of asthma and Mycoplasma pneumoniae infection, and eosinophil markers reflect the clinical stage of asthma. The purpose of this study was to investigate the change of eosinophil markers according to the clinical stage of Mycoplasma pneumonia. Methods : The patient group consisted of 33 outpatient children with Mycoplasma pneumonia. Peripheral blood total eosinophil count(TEC) and serum eosinophilic cationic protein(ECP) level were measured at both acute and recovery stages and were compared between both stages. The patient group was subdivided into the wheezing(n=16) and the nonwheezing group(n=17), and the TECs and the ECPs of one group were compared with those of the other group. The correlation between Mycoplasma antibody titer and the eosinophil markers of acute stage were analyzed. Results : In the whole patient group, the TECs and the ECPs of the acute stage were significantly higher than those of the recovery stage(P=0.018, P=0.005), but there were no differences in the TEC and the ECP between the wheezing and the nonwheezing group. In the wheezing group, there were no significant differences in the TEC and the ECP between acute and recovery stages. There were no correlations between acute stage Mycoplasma antibody titer and the eosinophil markers. Conclusion : Eosinophil markers reflect the clinical stage of Mycoplasma pneumonia and eosinophilic inflammations may continue even after the acute stage in wheezing patients with Mycoplasma pneumonia.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2004.11a
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• pp.31-32
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• 2004

In order to at day evaluate effect of dietary 2.0 % brown seaweed(Undaria pinnatifida) with bean extract on performance and nutrients utilization during acute phase response, one day-old broiler chicks were fed basal diet and diets substituted with 2.0 % brown seaweed and 2.0 % brown seaweed with bean extract instead of wheat bran in basal diet for 4weeks. Dietary 2.0 % brown seaweed with bean extract enhanced dietary ME value and protein accumulation due to the increased NB and decreased UAN excretion. increased feed intake during acute phase response and had the highest body weight among birds fed experimental diets. The resulted indicated that dietary 2.0 % brown seaweed with bean extract improved performance of broiler chicks due to the increased protein accumulation during acute phase response.

• Journal of the Korean Society of Radiology
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• v.83 no.5
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• pp.1046-1058
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• 2022

The hippocampus is one of the most metabolically active regions of the brain; therefore, it may be affected by various acute disorders. This study aimed to introduce and categorize various acute conditions that can involve the hippocampus and explain the findings of MRI, especially diffusion-weighted imaging (DWI). Acute hippocampal disorders are divided into six categories: infection, inflammation, metabolic, ischemic, traumatic, and miscellaneous. In this study, patients were retrospectively reviewed based on clinical findings and MRI, especially DWI. All diseases had been confirmed clinically or pathologically. Many acute hippocampal disorders overlap with the clinical manifestations. Thus, it is necessary to categorize acute hippocampal lesions and understand their specific imaging findings for differential diagnosis.

• Pediatric Infection and Vaccine
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• v.22 no.3
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• pp.206-209
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• 2015

We report the case of a 7-year-old boy who showed treatment-nonresponsive hypotension (59/29 mmHg) and decreased left ventricular systolic function (fractional shortening 22%) in the acute stage of Kawasaki disease (KD). The present case serves to highlight that methylprednisolone pulse therapy should be considered in patients with intravenous immunoglobulin nonresponsive symptomatic myocarditis during the acute stage of KD.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.238-238
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• 1994

녹용의 알려진 약리작용 중에서 녹용의 상용량 투여에 의해 나타나는 것은 강장작용과 창상치유작용이므로 이러한 작용이 진정한 녹용의 효능으로 간주될 수 있으나 이러한 작용을 생물활성 검색법으로 활용하여 녹용의 유효성분을 검색하기에는 재현성과 간편성이라는 면에서 어려운 점이 없지 않다. 녹용의 효능이 생체의 질소평형이 음의 방향으로 진행되었을 때 이를 정상 수준으로 복귀시키는 생물활성에 기인할 것이라는 가정하에서, 실험적으로 생체내 질소편형을 음의 방향으로 전환시킬 수 있는 급성기 반응 (acute-phase responce)을 야기시킨 다음 녹용의 효과를 연구하였다. 흰쥐의 급성기 반응물질 (acute-phase reactants, APR) 중에 서 positive ARP인 ceruloplasmin, $\alpha$-cysteine pretense inhibitor(= T-kininogen)는 비색정량법으로 간편하게 측정될수 있음에 착안하여 이 단백질을 지표로 삼아 turpentine oil로 급성 염증을 유발시킨 전후에 녹용 물추출액의 효과를 측정하였다. 그 결과 녹용의 상용량에서 괴소 4일 이상 경구투여한 흰쥐에서 급성 염증유발 후 4일에서 ceruloplasmin 의 혈중농도가 현저히 감소함을 알수 있었다. 급성 염증 유발후 녹용의 경구투여한 실험에서는 적어도 녹용 상용량의 3배 이상을 투여하여야 만 ceruloplasmin 혈중 농도를 감소시킬 수 있었다. 본 연구에서 수립된 생물활성을 이용하여 녹용의 유효 성분을 단리할 계획이다.

• Journal of Animal Science and Technology
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• v.46 no.2
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• pp.173-182
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• 2004

The effect of dietary Antartic krill(Euphausia Superba) meal on the performance of broiler chicks during the acute phase responses was studied. One d-old male broiler chicks(Avian) were fed on the experimental basal (0.0 % krill meal), and 0.5 and 1.0 % krill meal diets, and then the acute phase response were activated by injecting Salmonella typhymurium lipopolisaccharide(LPS) three times i. p. at 8, 10 and 12 day of age. The 1.0% krill meal diet group had reduced daily gain and feed efficiency during the acute phase response of the 2nd week of age, while during recovery from the acute phase response of the 3rd week of age the lowered performance disappeared. The acute phase response increased the relative weight of liver and spleen, and dietary krill meal enhanced the activities of MnSOD and Cu/ZnSOD in liver and erythrocyte cytosols during the acute phase response, although neither the acute phase response or dietary krill meal affected significantly PHA-p hypersensitivity. The results indicated that dietary krill meal affected the performance and SOD activity of broilers chicks during the acute phase response.

• Clinical and Experimental Pediatrics
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• v.50 no.10
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• pp.995-1004
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• 2007

Purpose : Kawasaki disease is a systemic vasculitis, leading cause of pediatric acquired heart disease. Vascular endothelial growth factor (VEGF) has functions as vascular permeability factor, plays an important role in coronary artery lesion (CAL). We studied the clinical significance of serum VEGF in Kawasaki disease. Methods : Kawasaki group was 49 patients, and control group was 15 patients. Diagnosis followed AHA (American Heart Association) diagnostic criteria, with blood sampling in acute, subacute, and convalescent phase. Echocardiographic abnormalities were defined and the definition of intravenous gamma globulin (IVGG)-responsive and IVGG-resistant was determined. Results : Serum VEGF of Kawasaki group was significantly higher than of control group. Comparison of serum VEGF between CAL and non-CAL group, between carditis group and non-carditis group showed no significant differences. Subacute serum VEGF was statistically higher in IVGG-resistant group than in IVGG-responsive group, and serum VEGF of IVGG-resistant group in subacute phase was statistically higher than in the other phases. Serum VEGF of convalescent CAL and non-CAL group in acute and subacute phase had meaningful differences. Total fever duration and subacute serum VEGF had positive correlation. Acute serum VEGF had positive correlation with ESR and CRP, all phases serum VEGF had also positive correlation with WBC. Acute and subacute serum VEGF had negative correlations with hemoglobin and albumin. Conclusion : Serum VEGF can help to determine the severity of Kawasaki disease, especially subacute serum VEGF seems to be used as a prognostic factor of coronary complication. Afterward, further studies needed with more strict diagnostic criteria and more study groups.

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.98-106
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• 2020

This study was conducted to identify the factors influencing the severity of pressure injuries of patients with pressure injuries admitted to acute university hospital. This study was a secondary analysis on the data of the study conducted to identify the factors influencing the deterioration of pressure injuries during hospitalization. The data were collected by retrospectively examining the medical records of patients with pressure injuries who were 18 years of age or older and who were admitted to acute university hospital from May 2017 to November 2018. We used data from 472 patients with pressure injuries at admission for this secondary analysis. In order to identify the factor influencing of severe pressure injuries compare to superficial pressure injuries, we analyzed the data using logistic regression analysis. As a result of the study, gender, body temperature, and patient's movement were identified as factors affecting severe pressure injuries. Therefore, special care is necessary to increased the number of position change for inpatients with pressure injuries, especially for patients with decreased mobility.

• Proceedings of the Korea Contents Association Conference
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• 2013.05a
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• pp.217-218
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• 2013

급성기 허혈성 뇌졸중 증상이 있는 뇌 관류 CT검사를 시행한 환자를 대상으로 장비사가 제시한 고정 시간 기법(fixed time technique)과 조영제 추적 기법(bolus tracking technique)을 비교하여 환자의 피폭선량을 분석하고자 하였으며 조영제 추적 기법의 유용성과 최적의 조영증강 구간을 구현하는 Time graph를 알아보기 위한 것이다.

• 대한불안의학회:학술대회논문집
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• 2004.06a
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• pp.243-258
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• 2004