Lee Jae-Joon;Lee Jeong-Hwa;Jeong Chang-Ju;Choi Hyun-Sook;Lee Myung-Yul
Food Science and Preservation
/
v.12
no.6
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pp.624-630
/
2005
Plantain was extracted with ethanol and fractionated systemically with n-hexane, chloroform, ethylacetate, n-butanol and water to study inhibitory effect on cholesterol synthesis in vitro. To screen the effect, inhibitory activities on 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase obtained from Saccharomyces cerevisiae were examined using the five fractions of Plantain. The HMG-CoA reductase activity was inhibited most by ehylacetate fraction among the fractions, although the all five fractions had the effect To see the hypocholesterolemic effect of the ethylacetate fraction of Plantanin (PAE) in vivo, male Sprague-Dawley rats were received 5 types of diets for 6 weeks: normal diet group (NOR), high cholesterol diet group($1\%$ cholesterol and $0.25\%$ sodium cholate, CON), normal diet and PAE 70 mg/kg administered group(S1), high cholesterol diet and PAE 140 mg/kg administrated group(S2), and high cholesterol diet and PAE 140 mg/kg administered group(S3). Body weight gains of the CON were significantly increased compared to those of S1, S2 and S3. Activities of serum AST and ALT were tended to be increased in CON compared with NOR and reduced by the PAE administration. Concentrations of serum total cholesterol, free cholesterol, LDL-cholesterol, triglyceride and the atherogenic index were tended to be decreased in the PAE administered groups compared with the CON. HDL-cholesterol and phospholipid concentrations were significantly decreased in the CON and markedly increased by the PAE administered groups. Taten together, it is suggested that the ethylacetate fraction of Plantanin exerts antiatherosclerotic effect by reducing serum cholesterol concentrations in rats fed high cholesterol diets.
Korean telephone surveys have been based on landline telephone directory or RDD(Random Digit Dialing) method. These days, however, there has been an increase of the households with no landline, or households with the line but not willing to register in the directory. Moreover, it is hard to contact young people or office workers who are usually staying out of home in the daytime. Due to these issues above, the predictability of election polls gets weaker. Especially, low accessibility to those who stay out of home when the poll's done, results in predictions with positive inclination toward conservatism. A solution to resolve this problem is to contact respondents by using both mobile and landline phones-via landline phone to those who are at home and via mobile phone to those who are out of home in the daytime(Mixed Mode Survey, hereafter MMS). To conduct MMS, 1) we need to obtain the sampling frames for the landline and mobile surveys, and 2) we need to decide the proportion of sample size of both. In this paper, we propose a heuristic method for conducting MMS. The method uses RDD for the landline phone survey, and the access panel list for the mobile phone survey. The proportion of sample sizes between landline and mobile phones are determined based on the 'Lifestyle and Time Use Study' conducted by Statistics Korea. As a case study, 4 election polls were conducted in the periods of the special election for the mayor of Seoul on Oct 26th, 2011. From the initial 3 polls, reactions and responses regarding the issues raised during the survey period were appropriately covered, and the final poll showed a very close prediction to the real election result.
Ku, Bon-Il;Choi, Min-Kyu;Kang, Shin-Ku;Park, Tae-Seon;Kim, Young-Doo;Park, Hong-Kyu;Kim, Bo-Kyong;Lee, Byun-Woo
KOREAN JOURNAL OF CROP SCIENCE
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v.57
no.4
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pp.441-448
/
2012
This study was carried out to evaluate the productivity of rice cultivation in extremely late season in Korea and to confirm the effects of pot-raising seedling culture in this case by assessing the growth and yield performance of rice cultivars that are well adapted to late culture. Suitable cultivars for extremely late culture should not have premature heading habit when transplanted around late July and also secure appropriate growth duration before heading. Geumobyeo 1 and Manjongbyeo showed small decrease in the emerged leaves in transplanting in late July or early August and heading occurred at the same time relatively without premature heading. At transplanting from late July to early August in extremely late rice cultivation, ripening was relatively good until transplanting on August 5. At transplanting on July 30, accumulated temperature from heading to the first frost was $853^{\circ}C$ and ripening was good enough. However, heading was delayed by low temperature at transplanting on August 10 and ripening was very poor due to low accumulated temperature of below $800^{\circ}C$, causing drastic decrease of rice yield. The rice yield increased in transplanting with pot seedling, especially the effects of pot seedling was higher in Geumobyeo 1, but panicle number was not enough to secure rice yield owing to short growth duration. In order to cultivate rice in extremely late season, we should select adaptive rice cultivars that have suitable growth duration and excellent ripening in low temperature. Here, pot-seedling did a great role to secure early growth and bigger growth amounts.
Purpose: Colorectal ranter is the 4th leading cause of cancer death in Korea and the prevalence is increasing continuously. This study was aimed to figure out the problems through the clinical consideration about terminal colorectal ranter patients who had died in hospice unit. Methods: We retrospectively reviewed the medical records in 78 patients with colorectal ranter who had admitted, received palliative care, and died in a hospice unit between April 2003 and November 2006. Results: The median age of patients was 59.6 years with 45 men (58%) and 24 women (42%). The median survival in hospice and palliative care was 36 days. The median hospitalization was 22 days. The most prevalent reason for admission was pain (38 patients, 49%), and the most common symptom was also pain (70 patients, 90%). Forty eight patients (62%) took analgesics before hospice referral. Twenty seven patients (65%) of 45 patients with intestinal obstruction have been performed palliative procedures. Median survival of patients with palliative procedure was higher than that of no palliative procedure group (47 days vs 19 days, P-value=0.005). Conclusion: The duration of hospice and palliative care was not enough to care the terminal colorectal cancer. Therefore, we suggest that proper education and information should be provided to physician, patients and their family members for effective hospice and palliative care.
We established the optimal conditions for the hot water extraction of Camellia japonica compounds based on the yield, the stability (observed by peak changes on an HPLC chromatogram), and the 1,1-diphenyl-1-picrylhydrazyl radical-scavenging activity of the extracts. The extracts were prepared at $90^{\circ}C$ using six solution volumes (ranging from 100 mL to 600 mL), and four different extraction times (10, 30, 60, and 120 min). The results showed that increasing of the extraction volume elevated the radical-scavenging activity of the extracts; however, changes in volume had minimal affects on their yields and their stabilities. An increase in extraction time improved the compound yield; however, it reduced their stability and increased the deterioration of their radical-scavenging activity. Based on our results, we propose the following conditions to be optimal for the hot water extraction of dried C. japonica leaves: a water volume (mL) that is 60 times the weight (g) of the sample at a temperature of $90^{\circ}C$ for 30 min.
O, Gun-Seop;An, Guk-Yeong;Kim, Yong-Mo;Lee, Chang-Sik
Transactions of the Korean Society of Mechanical Engineers B
/
v.20
no.7
/
pp.2386-2396
/
1996
A numerical simulation has been performed for isothermal and reacting flows in an exisymmetric, bluff-body research combustor. The present formulation is based on the density-weighted averaged Navier-Stokes equations together with a k-epsilon. turbulence model and a modified eddy-breakup combustion model. The PISO algorithm is employed for solution of thel Navier-Stokes system. Comparison between measurements and predictions are made for a centerline axial velocities, location of stagnation points, strength of recirculation zone, and temperature profile. Even though the numerical simulation gives acceptable agreement with experimental data in many respects, the present model is defictient in predicting the recoveryt rate of a central near-wake region, the non-isotropic turbulence effects, and variation of turbulent Schmidt number. Several possible explanations for these discrepancies have been discussed.
Park, Yang-Kyun;Ha, Sung-Whan;Ye, Sung-Joon;Cho, Woong;Park, Jong-Min;Park, Suk-Won;Huh, Soon-Nyung
Radiation Oncology Journal
/
v.24
no.4
/
pp.300-308
/
2006
$\underline{Purpose}$: To develop a wireless CCTV system in semi-beam's eye view (BEV) to monitor daily patient setup in radiation therapy. $\underline{Materials\;and\;Methods}$: In order to get patient images in semi-BEV, CCTV cameras are installed in a custom-made acrylic applicator below the treatment head of a linear accelerator. The images from the cameras are transmitted via radio frequency signal (${\sim}2.4\;GHz$ and 10 mW RF output). An expected problem with this system is radio frequency interference, which is solved utilizing RF shielding with Cu foils and median filtering software. The images are analyzed by our custom-made software. In the software, three anatomical landmarks in the patient surface are indicated by a user, then automatically the 3 dimensional structures are obtained and registered by utilizing a localization procedure consisting mainly of stereo matching algorithm and Gauss-Newton optimization. This algorithm is applied to phantom images to investigate the setup accuracy. Respiratory gating system is also researched with real-time image processing. A line-laser marker projected on a patient's surface is extracted by binary image processing and the breath pattern is calculated and displayed in real-time. $\underline{Results}$: More than 80% of the camera noises from the linear accelerator are eliminated by wrapping the camera with copper foils. The accuracy of the localization procedure is found to be on the order of $1.5{\pm}0.7\;mm$ with a point phantom and sub-millimeters and degrees with a custom-made head/neck phantom. With line-laser marker, real-time respiratory monitoring is possible in the delay time of ${\sim}0.17\;sec$. $\underline{Conclusion}$: The wireless CCTV camera system is the novel tool which can monitor daily patient setups. The feasibility of respiratory gating system with the wireless CCTV is hopeful.
Ham, S.K.;Song, T.H.;Zhang, G.Q.;Hur, S.N.;Park, H.S.
Korean Journal of Poultry Science
/
v.33
no.3
/
pp.233-238
/
2006
In order to study the effect of feeding rare earth(RE) on growth of broiler chicks, feed conversion ratio, and probable harmfulness of feeding high levels of RE, two feeding trials with broiler chicks were conducted; one using a commercial broiler compound feed and the other using a self mixed feed excluding any growth stimulating feed additives. The the first trial used three hundred sixty of one day old Cobb broiler chicks for six levels of dietary supplementation of RE : 0, 100, 200, 400, 800 and 1,600 mg/kg. There were significant effect of RE stimulating broiler chick growth and improving feed conversion ratio, The dietary supplementation of RE at a level of 100 mg/kg was the best of all and increased body weight gain by 8.9% (p<0.05). Chicks fed RE at a level of 1,600 mg/kg grew as good as chicks fed feeds without RE and did not show my abnormalities. The second feeding trial was conducted in the same manner as the first trial using Ross broiler chicks and self-mixed experimental diets supplemented with RE at levels of 0, 50, 100 and 150 mg/kg. Differently from Results of the first trial, body weight gain and feed conversion ratio of were the best at the level of 50 mg/kg RE supplementation(p<0.05). In this trial all the birds fed RE showed significantly lower ratio of abdominal fat against live weight than those of the control group birds. Overall, it can be said that dietary supplementation of RE will improve broiler growth and feed conversion ratio and the proper dietary level would be $50\sim100mg/kg$. These results suggested that the proper level of RE for broiler chicks would be 50 to 100 mg/kg and its effectiveness is varied depending upon RE mixture. There appears abdominal fat of broiler chicks is decreased by feeding RE but further investigation is in need.
Kim, Myoungju;Im, Inchul;Lee, Jaeseung;Kang, Suman
Journal of the Korean Society of Radiology
/
v.7
no.2
/
pp.157-163
/
2013
This study was to analyze quantitatively movement of planning target volume (PTV) and change of PTV volume through movement of diaphragm according to breathing phase. The purpose of present study was to investigate optimized respiration phase for radiation therapy of lung cancer. Simulated breathing training was performed in order to minimize systematic errors which is caused non-specific or irregular breathing. We performed 4-dimensional computed tomography (4DCTi) in accordance with each respiratory phase in the normalized respiratory gated radiation therapy procedures, then not only defined PTVi in 0 ~ 90%, 30 ~ 70% and 40 ~ 60% in the reconstructed 4DCTi images but analyzed quantitatively movement and changes of volume in PTVi. As a results, average respiratory cycle was $3.4{\pm}0.5$ seconds by simulated breathing training. R2-value which is expressed as concordance between clinically induced expected value and actual measured value, was almost 1. There was a statistically significant. And also movement of PTVi according to each respiration phase 0 ~ 90%, 30 ~ 70% and 40 ~ 60% were $13.4{\pm}6.4mm$, $6.1{\pm}2.9mm$ and $4.0{\pm}2.1mm$ respectively. Change of volume in PTVi of respiration phase 30 ~ 70% was decreased by $32.6{\pm}8.7%$ and 40 ~ 60% was decreased by $41.6{\pm}6.2%$. In conclusion, PTVi movement and volume change was reduced, when we apply a short breathing phase (40 ~ 60%: 30% duty cycle) range. Furthermore, PTVi margin considered respiration was not only within 4mm but able to get uniformity of dose.
The results of analyzing the difference between performances of individual dosimeters on this research subjecting the PLD and TLD, which are the official personal dosimeters, through dosimetry are as follows. After scanning the integral dose using an automatic scanner, the values of two devices that went through dose adjustment process had a statistical difference in TLD and PLD measurements under each filming conditions which were 70kVp, 200mA, 0.012sec and 42kVp, 100mA, and 0.012sec (p<0.001 and p<0.001 respectively). As for the difference of measurement value between DAP and the two particles under 70kVp, 200mA, 0.012sec filming condition, TLD had a value lower than DAP average value by $44.2mGy{\cdot}cm^2$ and PLD had a value of $246.8mGy{\cdot}cm^2$ which was lower than DAP average value by $15.5mGy{\cdot}cm^2$, while under 42kVp, 100mA, 0.012sec filming condition, TLD had a value lower than DAP average value by $17.9mGy{\cdot}cm^2$ and PLD had a value of $82.6mGy{\cdot}cm^2$ which was lower than DAP average value by 7.6$mGy{\cdot}cm^2$. Also, compared to PLD, each of 10 devices measured dose value in TLD had a larger deviation between the particles, and for a reproducibility test which repeatedly measured one particle, PLD had ${\pm}1%$ which was lower than TLD's ${\pm}2%$. As such, PLD had a superior performance result in dose measurement capacities aspect compared to TLD, and therefore we could verify that PLD is more appropriate and advantageous in managing radiation-related task performing worker's personal radiation exposure management in the diagnostic radiation field.
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