• Title/Summary/Keyword: 근전이

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Sinonasal Rhabdomyosarcoma Metastasis in Bilateral Multiple Extraocular Muscles: A Case Report and Brief Literature Review (부비동과 비강 내 횡문근육종의 양측 다발성 외안근 전이: 증례 보고와 문헌고찰)

  • So-Hyun Ji;Ji Hye Jang
    • Journal of the Korean Society of Radiology
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    • v.82 no.1
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    • pp.225-230
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    • 2021
  • Isolated metastasis in the extraocular muscle (EOM) is uncommon, while metastases in bilateral multiple EOMs is even rarer. Rhabdomyosarcoma (RMS) is a rare soft-tissue malignancy that usually occurs in the pediatric population and is one of the primary malignancies of isolated EOM metastasis. Here, we present a case of sinonasal RMS metastasis to multiple bilateral EOMs along with a brief review of 10 previously reported cases of RMS metastasis in EOMs.

Multifocal Skeletal Muscle Metastasis from Kidney Cancer (Transitional Cell Carcinoma) - A Case Report - (신장암의 다발성 골격근 전이 - 1례 보고 -)

  • Rhee, Seung-Koo;Kang, Yong-Koo;Park, Won-Jong;Chung, Jin-Wha;Sur, Yoo-Joon
    • The Journal of the Korean bone and joint tumor society
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    • v.8 no.2
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    • pp.48-53
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    • 2002
  • Although direct skeletal muscle invasion by carcinoma is well recognized, distant metastasis to skeletal muscle is uncommon. Furthermore, multifocal skeletal muscle metastasis is a very exceptional event. Some factors such as variable intra-muscular blood flow, mechanical factors including turbulent blood flow and muscle contraction, intra-muscular acidic condition, lactic acid, protease inhibitors in the extra-cellular matrix were proposed as causes of the rarity of distant metastasis to skeletal muscle. We report here a case of a 67 year old male who had multifocal skeletal muscle metastasis from the transitional cell carcinoma of left kidney.

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The Role Of Tumor Marker CA 15-3 in Detection of Breast Cancer Relapse After Curative Mastectomy (유방암 환자에서 근치적 유방 절제술 후 재발 발견에 대한 CA 15-3의 역할)

  • Hyun, In-Young;Kim, In-Ho;Lee, Moon-Hee;Kim, Chul-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.38 no.4
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    • pp.311-317
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    • 2004
  • Purpose: The purpose of this study was to determine the utility of tumor marker CA 15-3 in the following: the diagnosis of breast cancer relapse after curative mastectomy, and the differentiation or the value of tumor marker by site of metastases. Materials and Methods: Two hundred two patients (median age 48 years) with breast cancer included in the follow-up after curative mastectomy. The tumor marker CA 15-3 was determined by IRMA (CIS BIO INTERNATIONAL, France). Test values > 30 U/ml were considered elevated (positive). Results: Among 202 patients, recurrent diseases were found in 16 patients. CA 15-3 was elevated in 5 of 16 patients with recurrences. There was no false-positive patient who had elevated CA 15-3. Sensitivity and specificity of CA 15-3 for detection of breast cancer recurrence were 31%, and 100%. CA 15-3 was elevated in all of the 4 patients with liver metastases. CA 15-3 was elevated in none of the patients who relapsed with metastasis to bone-only or contralateral breast-only. Conclusion: The tumor marker CA 15-3 in the detection of breast cancer relapse after curative mastectomy is specific, but not sensitive. However, it is useful to rule out liver metastases of breast cancer, which indicates bad prognosis.

Clinical Applications of $^{18}F$-FDG PET/CT in Malignant Bone and Soft Tissue Tumors (악성 골 및 연부조직 종양에서 $^{18}F$-FDG PET/CT의 임상적 적용)

  • Shin, Duk-Seop
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.86-94
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    • 2008
  • $^{18}F$-FDG PET/CT has led to advancement in diagnostic imaging, providing correlation of both physiology and anatomic information, and to new and innovative ways to utilize PET/CT imaging for the evaluation of musculoskeletal tumors. Recently, the most widely utilized musculoskeletal application of PET/CT imaging is for the detection and characterization of bone metastases, staging and restaging of primary malignant bone tumors and soft tissue sarcomas. And it is also useful in evaluating response to therapy for malignant musculoskeletal tumors and in detecting local recurrences or distant metastases during follow up. The future likely holds even more unique and potentially quite useful applications of PET/CT imaging for primary bone and soft tissue tumors. This article will review the useful applications of $^{18}F$-FDG PET/CT imaging for evaluating musculoskeletal tumors.

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Curative Resection of Inoperable, Locally Advanced Gastric Cancer after Neoadjuvant Chemotherapy with Taxotere and Cisplatin (절제 불가능한 국소 진행성 위암 환자에서 Taxotere 및 Cisplatin을 이용한 선행 화학 요법제의 투여 후 근치적 절제가 가능했던 2예)

  • Lee, Han-Hong;Hur, Hoon;Chae, Byung-Joo;Kim, Wook;Jeon, Hae-Myung
    • Journal of Gastric Cancer
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    • v.5 no.1
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    • pp.57-64
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    • 2005
  • At diagnosis, the majority of patients with gastric cancer are found to have local invasion or distant organ metastasis, even though the sole measure for a complete cure is a curative resection. A curative resection is hardly applicable for those with invasion and metastasis; thus, trials with neoadjuvant chemotherapy for downstaging the cancer should be considered. Docetaxel is a semisynthetic taxane that promotes tubulin polymerization and inhibits microtubule depolymerization. In recent studies, many metastatic gastric cancers were treated using neoadjuvant chemotherapy with docetaxel, and the response rates were reported. We report here two cases of locally advanced, non-resectable gastric cancer that were candidates for a curative resection after induction chemotherapy with docetaxel and cisplatin.

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Metastasizing Pleomorphic Adenoma in Right Lung -A case report - (우측 폐로 전이된 전이성 다형태 선종 -증례 보고-)

  • Chung, Won-Sang;Nam, Seung-Hyuk;Kang, Jeong-Ho;Kim, Young-Hak;Kim, Eung-Soo;Kim, Hyuck
    • Journal of Chest Surgery
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    • v.40 no.2 s.271
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    • pp.143-146
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    • 2007
  • A metastasizing pleomorphic adenoma originating from the parotid gland is a rare form of neoplasm. The neoplasm is a histologically benign, but clinically controversial entity. Herein, a case report of a pleuro-pneumonectomy of a metastasizing pleomorphic adenoma in the right lung is described. A 57-year-old man, who underwent resection of parotid gland due to a pleomorphic adenoma, presented with multiple metastases on the right lung, mediastinum, pericardium and intercostal muscle. The metastatic lesions were composed of a benign pleomorphic structure.

A Case Report of a Gastric Cancer Patient with a Good Quality of Life after Radiotherapies to 17 Metastases for 4 Years (4년간 17 전이부위에 방사선치료를 받은 위암 환자의 증례보고)

  • Yun, Hyong-Geun
    • Radiation Oncology Journal
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    • v.29 no.2
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    • pp.127-133
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    • 2011
  • Five and half years ago, a 45-year-old female metastatic gastric cancer patient underwent a metastatectomy and chemotherapy. Over the last 4 years and 2 months, she received radiotherapy for every new distant metastasis with intermittent TS-1 oral chemotherapy. She received 8 courses of radiotherapy at 17 metastatic sites for more than 4 years. Metastatic sites which received a curative radiation dose achieved and maintained local control. The patient is now 51 years of age and lives without difficulty in performing her daily activities.

Photocatalytic degradation of a polycyclic aromatic sulfur hydrocarbon ($TiO_2$를 이용한 다환 방향족 유기황 탄화수소의 광분해효율 연구)

  • Jo Seoung-Hye;Lee Sang-Geun;Lee Je-Geun;Kim Il-Gyu
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2005.04a
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    • pp.163-166
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    • 2005
  • [ $TiO_2$ ] 광촉매에 의한 분해 반응의 활성을 높이기 위한 다양한 연구가 진행되었다. 광촉매 반응은 1차 반응을 따랐으며 초기농도가 높을수록 분해효율이 감소하는 경향을 보였다. 본 연구에서는 산화제로 과산화수소가 주입되었을 경우 분해효율을 조사하였으며, 과산화수소를 주입하였을 경우가 그렇지 않은 경우보다 더 높은 분해효율을 보였다. 또한 과산화수소 주입량을 달리했을 때, 주입량이 증가할수록 효율이 높아지다가 일정량 이상에서는 오히려 효율이 감소하는 것으로 나타났다. 따라서 과산화수소 최적첨가량이 존재함을 알 수 있었다. 한편 $TiO_2$에 전이금속을 첨가하여 전이금속이 $TiO_2$ 촉매의 분해효율에 미치는 영향을 알아보았다. Pt(0.5%)-$TiO_2$가 가장 높은 분해효을을 보였으며, Pt첨가함량이 더 큰 Pt(2%)-$TiO_2$는 함량이 증가했음에도 불구하고 큰 차이는 아니지만 오히려 효율이 감소하였다. 따라서 촉매표면에서 전자와 정공이 생성되었을 때, Pt가 전자를 포획함으로써 전자와 정공의 재결합율을 감소시켜 OH라디칼을 생성할 수 있는 정공이 많아져 반응효율을 증가되는 것을 알 수 있었고, 금속에 따른 최적 첨가함량이 존재함을 알 수 있다. 반면에 Pd를 첨가했을 경우는 첨가 함량에 관계없이 모두 분해효율이 오히려 감소하는 경향을 나타냈으며 이는 전이금속 고유의 성질이나, 또는 대상물질에 따라 각기 다른 경향이 존재함을 나타내며 추가적인 연구가 필요하다고 사료된다.

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Diagnosis of Primary Malignant Lesion Using $^{18}F$ FDG PET/CT in Metastatic Bone Tumor (전이성 골종양에서 $^{18}F$ FDG PET/CT를 이용한 원발성 악성 질환의 진단)

  • Yoon, Hoi-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.1
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    • pp.44-50
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    • 2008
  • Purpose: To evaluate usefulness in diagnosing primary malignant lesion of metastatic bone tumor using $^{18}F$ FDG PET/CT. Material & Methods: Retrospective analysis was executed on 5,452 patients who were taken with $^{18}F$ FDG PET/CT between December 2003 and December 2007. 180 patients who had not any history of malignancy and complained musculoskeletal pain and had ill-defined osteolytic lesion in plain X-ray, were included. 96 male and 84 female were enrolled and mean age was 59.1 year old (22~90). We analyzed diagnostic accuracy, age and sex distribution of primary malignant lesion, location of metastatic lesion. Results: We could confirmed primary malignant lesion in 152 cases (84.4%). Most common malignant primary lesion was lung (28.3%), breast (18.9%) and gastrointestinal system (16.7%) and spine was the most common metastatic location of primary malignant lesion. Conclusion: $^{18}F$ FDG PET/CT is a effective molecular imaging detecting primary malignant lesion in patients having metastatic bone lesion without history of malignancy.

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