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Analysis of Polymer Characteristics Using Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry (말디토프 질량분석을 이용한 고분자의 특성분석)

  • Kang, Min-Jung;Seong, Yunseo;Kim, Moon-Ju;Kim, Myung Soo;Pyun, Jae-Chul
    • Applied Chemistry for Engineering
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    • v.28 no.3
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    • pp.263-271
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    • 2017
  • The application of mass spectrometry to polymer science has rapidly increased since the development of MALDI-TOF MS. This review summarizes current polymer analysis methods using MALDI-TOF MS, which has been extensively applied to analyze the average molecular weight of biopolymers and synthetic polymers. Polymer sequences have also been analyzed to reveal the structures and composition of monomers. In addition, the analysis of unknown end-groups and the determination of polymer concentrations are very important applications. Hyphenated techniques using MALDI-tandem MS have been used for the analysis of fragmentation patterns and end-groups, and also the combination of SEC and MALDI-TOF MS techniques is recommended for the analysis of complex polymers. Moreover, MALDI-TOF MS has been utilized for the observation of polymer degradation. Ion mobility MS, TOF-SIMS, and MALDI-TOF-imaging are also emerging technologies for polymer characterization because of their ability to automatically fractionate and localize polymer samples. The determination of polymer characteristics and their relation to the material properties is one of the most important demands for polymer scientists; the development of software and instrument for higher molecular mass range (> 100 kD) will increase the applications of MALDI-TOF MS for polymer scientists.

An Efficient Dynamic Workload Balancing Strategy (PIECES 프레임워크 중심의 요구사항 정제와 우선순위 결정 전략)

  • Jeon, Hye-Young;Byun, Jung-Won;Rhew, Sung-Yul
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.10
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    • pp.117-127
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    • 2012
  • Identifying user requirements efficiently and reflecting them on the existing system is very important in a rapidly changing web and mobile environments. This study proposes the strategies to refining requirements and to prioritizing those refined requirements for changing of web and mobile application based on user requirements (e.g. mobile application comments, Q&A, reported information as discomfort factors). In order to refining the user requirements, those requirements are grouped by using the advancement of the software business of the Forum of standardization and the existing configuration-based programs. Then, we mapped them onto the PIECES framework to identifying whether the refined requirements are correctly reflected to the system in a way of valid and pure. To determine the priority of refined requirements, first, relative weights are given to software structure, requirements and categories of PIECES. Second, integration points on each requirement are counted to obtain the relative value of partial and overall score of a set of software structural requirements. In order to verifying the possibility and proving the effectiveness of proposing technique in this study, survey was conducted on changing requirements of mobile application which have been serviced at S University by targeting 15 people of work-related stakeholders.

Comparison Measurement Error of T-score Between Lumbar and Femoral Neck According to Kind of DXA (DXA측정기 종류에 따른 요추부와 대퇴경부 골밀도 값의 측정오차 비교)

  • Han, Beom-Hee;Jung, Hong-Ryang;Lim, Cheong-Hwan;Lee, Hye-Nam;Jeong, Cheon-Soo;Lee, Sang-Ho
    • The Journal of the Korea Contents Association
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    • v.10 no.3
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    • pp.250-257
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    • 2010
  • In this study, three different devices, Norland, Osteocore and Lunar were used to compare and analyze the measurement error by each bone density measurement device by classifying the physical characteristics into age, height and weight, the subject of total 300 sampling 100 persons for each device. Categorizing Lumbar region and Femoral neck as normal (T-score$\geqq$-1.0), osteopenia (-1.0>T-score>-2.5) and osteoporosis (T-score$\leqq$-2.5), the findings were observed as follows. Norland device showed the least measurement error in age and height, while Lunar showed the least in weight among the devices. And, the result of comparing the bone density measurement error based on the lumbar region showed that all of Lunar, Norland and Osteocore have the least variation of measurement error in osteopenia and the result of comparing based on the femoral neck showed that all of Lunar, Norland and Osteocore have the least variation of measurement error in osteoporosis. For each variable, the measurement error was observed to be vary upon the device. To solve this, standardized common Phantom should be used to compare and converge the measured value of each company and cross-calibration would be necessary when replacing the software.

A Dynamic Orchestration Framework for Supporting Sustainable Services in IT Ecosystem (IT 생태계의 지속적인 운영을 위한 동적 오케스트레이션 프레임워크)

  • Park, Soo Jin
    • KIPS Transactions on Software and Data Engineering
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    • v.6 no.12
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    • pp.549-564
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    • 2017
  • Not only services that are provided by a single system have been various with the development of the Internet of Things and autonomous software but also new services that are not possible before are provided through collaboration between systems. The collaboration between autonomous systems is similar to the ecosystem configuration in terms of biological viewpoints. Thus, it is called the IT Ecosystem, and this concept has arisen newly in recent years. The IT Ecosystem refers to a concept that achieves a mission of each of a number of heterogeneous systems rather than a single system utilizing their own autonomy as well as achieving the objectives of the overall system simultaneously in order to meet a single common goal. In our previous study, we proposed architecture of elementary level and as well as basic several meta-models to implement the IT Ecosystem. This paper proposes comprehensive reference architecture framework to implement the IT Ecosystem by cleansing the previous study. Among them, a utility function based on cost-benefit model is proposed to solve the dynamic re-configuration problem of system components. Furthermore, a measure of using genetic algorithm is proposed as a solution to reduce the dynamic re-configuration overhead that is increased exponentially according to the expansion of the number of entities of components in the IT Ecosystem. Finally, the utilization of the proposed orchestration framework is verified quantitatively through probable case studies on IT Ecosystem for unmanned forestry management.

Development of a New Training System for the Improvement of Equibrilium Sense (평형 감각 증진을 위한 새로운 훈련 장치의 개발)

  • Lee Jung Ok;Park Young Gun;No Pang Hwang;Hong Chul Un;Kim Nam Gyun
    • Journal of Biomedical Engineering Research
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    • v.25 no.6
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    • pp.465-469
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    • 2004
  • We propose a new training system for the improvement of equilibrium sense using unstable platform. This system consists of unstable platform, computer interface and various softwares. The unstable platform was a simple structure of elliptical-type which included tilt sensor and wireless RF module. To evaluate the effort of balance training, we measured the parameters such as the moving time to the target and duration to maintain cursor in the target of screen. Balance training was carried out for two weeks and we classified the subjects into two groups by the training program. As a result, the moving time was reduced and duration time was lengthened through the repeating training of equilibrium sense using training program of sine curve trace(SCT) and Block game. Especially, there was remarkable improvement at direction which was too difficult for the subjects to balance their body. It was showed that this system had an effort on improving equilibrium sense and might be applied to clinical use as an effective balance training system.

A Study on User Interface of the Broadband Access Network Operation Support System (광대역 가입자망 운용관리를 위한 그래픽 유저 인터페이스(GUI) 개발에 관한 연구)

  • 장은상;이종호;임현민;하동석
    • Archives of design research
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    • v.12 no.4
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    • pp.61-68
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    • 1999
  • Most of the time, developers spend their energy to analyze the main function of the system or make source codes. As a result, they can not consider user interface on their own system and this is true in most programmer's world. But we want to consider the design concept in developing mechanism. In this case we have to upgrade the legacy system which maintaining the transmission system using the copper cables, and add the transmission system using the optical fiber cables. Therefore we design the user interface make easy for end users who are using the maintaining system on copper cables not to confuse the new system which include optical fibers. Especially, we are consider the developing model of design policy and real user to make easy to use new system. In this paper we will describe the instance to adapt the design concept on Broadband Access Network Operation Support System.

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Industrial Technology Leak Detection System on the Dark Web (다크웹 환경에서 산업기술 유출 탐지 시스템)

  • Young Jae, Kong;Hang Bae, Chang
    • Smart Media Journal
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    • v.11 no.10
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    • pp.46-53
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    • 2022
  • Today, due to the 4th industrial revolution and extensive R&D funding, domestic companies have begun to possess world-class industrial technologies and have grown into important assets. The national government has designated it as a "national core technology" in order to protect companies' critical industrial technologies. Particularly, technology leaks in the shipbuilding, display, and semiconductor industries can result in a significant loss of competitiveness not only at the company level but also at the national level. Every year, there are more insider leaks, ransomware attacks, and attempts to steal industrial technology through industrial spy. The stolen industrial technology is then traded covertly on the dark web. In this paper, we propose a system for detecting industrial technology leaks in the dark web environment. The proposed model first builds a database through dark web crawling using information collected from the OSINT environment. Afterwards, keywords for industrial technology leakage are extracted using the KeyBERT model, and signs of industrial technology leakage in the dark web environment are proposed as quantitative figures. Finally, based on the identified industrial technology leakage sites in the dark web environment, the possibility of secondary leakage is detected through the PageRank algorithm. The proposed method accepted for the collection of 27,317 unique dark web domains and the extraction of 15,028 nuclear energy-related keywords from 100 nuclear power patents. 12 dark web sites identified as a result of detecting secondary leaks based on the highest nuclear leak dark web sites.

Clustering Technique of Intelligent Distance Estimation for Mobile Ad-hoc Network (이동 Ad-hoc 통신을 위한 지능형 거리추정 클러스터방식)

  • Park, Ki-Hong;Shin, Seong-Yoon;Rhee, Yang-Won;Lee, Jong-Chan;Lee, Jin-Kwan;Jang, Hye-Sook
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.11
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    • pp.105-111
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    • 2009
  • The study aims to propose the intelligent clustering technique that calculates the distance by improving the problems of multi-hop clustering technique for inter-vehicular secure communications. After calculating the distance between vehicles with no connection for rapid transit and clustering it, the connection between nodes is created through a set distance vale. Header is selected by the distance value between nodes that become the identical members, and the information within a group is transmitted to the member nodes. After selecting the header, when the header is separated due to its mobility, the urgent situation may occur. At this time, the information transfer is prepared to select the new cluster header and transmit it through using the intelligent cluster provided from node by the execution of programs included in packet. The study proposes the cluster technique of the intelligent distance estimation for the mobile Ad-hoc network that calculates the cluster with the Store-Compute-Forward method that adds computing ability to the existing Store-and-Forward routing scheme. The cluster technique of intelligent distance estimation for the mobile Ad-hoc network suggested in the study is the active and intelligent multi-hop cluster routing protocol to make secure communications.

Recent Progress in Micro In-Mold Process Technologies and Their Applications (마이크로 인몰드 공정기술 기반 전자소자 제조 및 응용)

  • Sung Hyun Kim;Young Woo Kwon;Suck Won Hong
    • Journal of the Microelectronics and Packaging Society
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    • v.30 no.2
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    • pp.1-12
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    • 2023
  • In the current era of the global mobile smart device revolution, electronic devices are required in all spaces that people interact with. The establishment of the internet of things (IoT) among smart devices has been recognized as a crucial objective to advance towards creating a comfortable and sustainable future society. In-mold electronic (IME) processes have gained significant industrial significance due to their ability to utilize conventional high-volume methods, which involve printing functional inks on 2D substrates, thermoforming them into 3D shapes, and injection-molded, manufacturing low-cost, lightweight, and functional components or devices. In this article, we provide an overview of IME and its latest advances in application. We review biomimetic nanomaterials for constructing self-supporting biosensor electronic materials on the body, energy storage devices, self-powered devices, and bio-monitoring technology from the perspective of in-mold electronic devices. We anticipate that IME device technology will play a critical role in establishing a human-machine interface (HMI) by converging with the rapidly growing flexible printed electronics technology, which is an integral component of the fourth industrial revolution.

A Study on The Measurement of Cerebral Cortical Thickness in Patients with Mood Disorders (기분장애 환자의 대뇌 피질 두께 측정에 관한 연구)

  • Do-Hun Kim;Hyo-Young Lee
    • Journal of the Korean Society of Radiology
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    • v.18 no.2
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    • pp.73-81
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    • 2024
  • This study compared the cortical thickness of patients with mood disorders and a control group to assess structural abnormalities. A retrospective study was conducted from September 2020 to August 2022 at the Department of Psychiatry, P Hospital in Yangsan, Gyeongsangnam-do. The study included 44 individuals diagnosed with mood disorders and 59 healthy individuals without any pathological lesions. The 3D-T1 MPRAGE images obtained from magnetic resonance imaging examinations were utilized, and FreeSurfer software was employed to measure cortical thickness. Statistical analysis involved independent samples t-tests to measure the differences in means between the two groups, and Cohen's d test was used to compare the effect sizes of the differences. Furthermore, the correlation between the measured average cortical thickness and Positive and Negative Syndrome Scale scores was analyzed. The research results revealed that patients with mood disorders exhibited decreased cortical thickness compared to the normal control group in both superior frontal regions, both rostral middle frontal regions, both caudal middle frontal regions, both pars opercularis, pars orbitals, pars triangularis regions, both superior temporal regions, both inferior temporal regions, both lateral orbitofrontal regions, both medial orbitofrontal regions, both fusiform regions, both posterior cingulate regions, both isthmus cingulate regions, both superior parietal regions, both inferior parietal regions, both supramarginal regions, left postcentral region, right bank of the superior temporal sulcus region, right middle temporal region, right rostral anterior cingulate region, and right insula region. Among them, regions that showed differences with effect sizes of 0.8 or higher were left fusiform (d=0.82), pars opercularis (d=0.94), superior frontal (d=0.88), right lateral orbitofrontal (d=0.85), and pars orbitalis (d=0.89). Additionally, there was a weak negative correlation between PANSS scores and average cortical thickness in both the left hemisphere (r=-0.234) and right hemisphere (r=-0.230). These findings are expected to be helpful in identifying areas of cortical thickness reduction in patients with mood disorders compared to healthy individuals and understanding the relationship between symptom severity and cortical thickness changes.