• Title/Summary/Keyword: 국화흰녹병균

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Genome Sequence Analysis of Chrysanthemum White Rust pathogen Puccinia horiana and Sterol 14-demethylase as Drug Target (국화흰녹병균 Puccinia horiana 유전체 분석과 약물 표적으로서의 sterol 14-demethylase)

  • Kim, Jeong-Gu;Park, Sang Kun;Park, Ha-Seung;Kwon, Soo-Jin;Kim, Seung Hwan;Lee, Dong-Jun;Sohn, Seong-Han;Lee, Byoung Moo;Bae, Shin-Chul;Ahn, Il-Pyung;Kim, Changhoon;Baek, Jeong Hun
    • The Korean Journal of Pesticide Science
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    • v.17 no.4
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    • pp.468-472
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    • 2013
  • Chrysanthemum is an economically important horticultural plant in many countries. The white rust is one of the most devastating diseases caused by an obligate fungal pathogen Puccinia horiana. This is being controlled mostly by application of chemicals. In Korea, 26 items are registered and 10 items contain 6 triazole compounds. To identify and to obtain the information of the drug target for triazoles, possible sterol 14-demethylase orthologues were extracted. From the draft genome information, the nucleotide sequence of the sterol 14-demethylase gene was identified. The amino acid sequence was deduced and the tertiary structure of the enzyme was predicted. This protein showed no less than 84% amino acid sequence identities to those of genus Puccinia and no more than 68% to those of other genus.