• Journal of Korean society of Dental Hygiene
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• v.12 no.5
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• pp.973-985
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• 2012

Objectives : The aim of this study is to investigate the possible impact factors on adults' self-reports of dry mouth and to develop strategies to improve oral health education policy. Methods : This study was conducted on a total of 622 self-administered questionnaires adult above 20 and under 65 years of age living in Seoul and Gyeonggi provinces. The final participants consisted of 443 adults without chronic illness, taking medications and wearing dentures. The Hierarchical Multiple Regression model with three stages was used to assess the association for exposure of interest, such as socio-demographics, health-related behavior, mental health and self-reported of dry mouth. Results : The participants reported mean score of dry mouth($6.32{\pm}4.47$), of which 191 were male($6.81{\pm}4.56$) and 252 were female($5.94{\pm}4.37$). Hierarchical Multiple Regression revealed that the score of dry mouth was shown to be significantly higher for the following people: Males, who were employed, unemployed, negative self-perceived general health, perceived stress, and participants who had no experience awareness of distress in two weeks. The explanatory power was 21.9%. The most powerful impact factor regarding to employment was shown to be negatively associated to dry mouth, and self-perceived general health, experiencing awareness of distressful in two weeks was also important factors. Conclusions : Based on these results in order to develop oral health education policy strategies for the prevention and management of dry mouth, there need to be considered for the employee.

• Journal of Oral Medicine and Pain
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• v.15 no.1
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• pp.9-25
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• 1991

타액의 유동학적 성질은 타액의 윤활작용 및 구강내 경조직, 연조직 보호작용에 영향을 미친다. 그러므로 타액의 유동성을 잘 이해하면, 구강내 기능적 불편감의 평가와 인공타액의 개발에 필요한 중요한 정보를 얻을 수 있다. 저자는 전단율 변화에 따른 타액점도 변화의 연령 및 성별에 따른 차이를 알고자, 각 연령층별로 구강건조증으로 고통받은 병력이 없으며 타액채취시 약물을 복용하고 있지 않은 남녀 각 20명씩 총 240명을 대상으로 자극시 분비된 타액의 점도를 cone-and-plate 형태의 점도계를 이용하여 전단율 11.3에서부터 450.0(/sec )사이에서 측정하였다. 또, 20대 남녀 각각 20명의 경우, 자극시 분비 된 전타액의 점도와 함께 비자극시 분비된 전타액, 자극시 분비된 이하선 타액, 자극시 분비된 악하선 설하선 혼합타액의 점도를 같은 방법으로 측정한 결과 다음과 같은 결론을 얻었다. 1. 타액은 점탄성의 성질을 가지는 non-Newtonian 유체로서 점도와 전단율 사이의 관계는 점근선으로 표시될 수 있었다. 2. 자극시 분비된 전타액의 점도는 연령이 높을수록 증가된 양상을 보였으나, 남자의 경우 50대 이상에서 가장 높고 여자의 경우 30대에서 가장 높았다. 3. 자극시 분비된 전타액의 점도는 20대, 30대, 40대에서 여자가 남자보다 높았다. 4. 타액 점도는 자극시 분비된 악하선 설하선 혼합타액에서 가장 높았으며, 비자극시 분비된 전타액, 자극시 분비된 전타액, 자극시 분비된 이하선 타액 순이었다.

• Journal of Oral Medicine and Pain
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• v.24 no.3
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• pp.245-257
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• 1999

일상 생활에서 우리는 스트레스에 항상 노출되어 있으며, 스트레스는 생체의 신경계, 내분비계 및 면역계의 변화를 수반한 항상성의 파괴로 수많은 정신적, 육체적 질병을 야기시킨다. 특히 구강안면영역에서도 다양한 구강점막질환과 구강건조증 등을 발생시킨다. 스트레스를 제거하는 방법으로는 약물요법 및 상담, 명상요법, 종교요법 등 다양한 방법이 제시되고 있는데, 다소의 부작용이 나타나거나 꾸준히 시행하기가 쉽지 않으며 스트레스의 원인을 근본적으로 제거하기가 현실적으로 용이하지 않은 경우가 많아 스트레스에 대한 해결책에 대하여 많은 관심이 집중되고 있다. 이에 본인은 스트레스가 가해졌을 때 백서 악하선에서 관철되며 apoptosis에 대하여 세포보호작용을 하는 clusterin(SGP-2)을 이용하여 구속스트레스를 가하기에 앞서 오랫동안 경험적으로 사용되어 왔고 부작용이 적은 전통약물인 보혈안신탕을 투여하고 스트레스에 의한 타액선의 조직변화를 관찰하여 그 효과를 확인해 보고자하였다. Sprague-Dawley계 응성 백서(200-230g/bw) 33마리를 정상 대조군(3마리), 구속스트레스군(15마리) 및 보혈안신탕 투여 후 구속스트레스군(15마리)으로 나누고 이틀을 각각 구속장치에 구속한 후 0, 1, 3, 5, 7일에 회생시켜 악하선을 적출하였으며, 면역조직화학법 및 Northern Blot을 이용하여 clusterin의 변화를 관찰하였다. 그 결과는 다음과 같다. 1. 구속스트레스군의 악하선 조직에서 clusterin 단백질과 mRNA는 실험 즉일군에서만 미약하게 관찰되었으며 실험 3일과 5일 후에 핵붕괴 및 핵농축 등의 핵변화를 동반한 apoptosis가 관찰 되었다. 2. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서 실험 5일군까지 clusterin 이 증가한 후 실험 7일군에서는 감소하였다. 3. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서는 apoptosis가 관찰되지 않았다. 4. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서 clusterin mRNA가 실험 전군에 걸쳐 미약하게 관찰되었다. 이상의 결과로 타액선 조직은 스트레스 단백질인 clusterin을 생산하여 세포를 보호함으로써 스트레스 상황에 적응하지만, 생리적 적용한계를 넘는 스트레스에 노출될 때는 apoptosis됨이 확인되었다. 그리고 보혈안신탕은 스트레스 상황에서 세포의 생리적 적응력을 높여 세포의 apoptosis를 억제하는 효과를 나타냄이 확인되었다. 따라서 본 연구결과는 구강건조증등의 스트레스성 타액선 질환의 병리기전을 규명하는데 도움이되리라 생각되며, 향후 항스트레스 효과를 가진 보혈안신탕등의 한약재를 임상에 적용함으로써 스트레스로 인한 신체의 병리적 변화를 다소나마 차단할 수 있을 것으로 사료된다.

• The Journal of the Korean dental association
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• v.42 no.6 s.421
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• pp.414-421
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• 2004

Sjogren syndrome is a chronic systemic autoimmune disorder that chiefly involves the salivary gland and the lacrimal gland, resulting in xerostomia and xerophthalmia. Although the exact cause of the disease is not early diagnosis, treatment and observation must be emphasized because of its poor prognosis, such as the high occurrence of malignant lymphoma and other autoimmune disease that may be accompanied. In the present case, a twenty-year-old woman whose chief complaint was multiple dental hard tissue loss and xerostomia, which was misdiagnosed as iron deficiency anemia at first, but through re-evaluation and differential diagnosis it was Sjogren syndrome. the diagnosis approach was discussed in this report, suggesting that Sjogren syndrome should be considered as a differential diagnosis in a with xerostomia.

• Journal of Oral Medicine and Pain
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• v.38 no.2
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• pp.137-142
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• 2013

Oral Medicine includes temporomandibular disorder, orofacial pains such as neuropathic pain, soft tissue diseases, halitosis, laser treatment, snoring, sleep apnea and identification through forensic dentistry etc. Such diseases are relatively common and cause great inconvenience and pain to the patients, as well as incur fatal health scare at times. In terms of oral medicine, the number of orofacial patients is growing due to a change in the life style and an increased stress as time goes in contemporary society and the demand of areas requiring oral medical professionalism, such as soft tissue lesions, snoring and sleep apnea, forensic dentistry evaluation and others are rapidly ascending. Consequently, among the areas in dental science, the calls for the expertism in oral medicine and its role are mounting. Analyzing the distribution according to disease entity, symptoms, duration of disease, and the prehistory courses of new patients visiting the department of oral medicine in a year provides information of the role and the relative importance of oral medicine in prospect and enables effective diagnosis and treatments for the patients. Therefore, in the present study, by analyzing new patients visiting the oral medicine clinic in our dental hospital for a year and by evaluating the role and the professionalism in future oral medicine, the authors concluded the followings: 1. It was founded that new patients to oral medicine mainly had temporomandibular disorders, soft tissue diseases, and neuropathic pains. 2. The number of patients with temporomandibular disorder appeared to be the highest percentage and the order within this was the patients with combined disorders, muscle disorder, and internal derangement of joint disc. 3. The number of patients with xerostomia appeared to be the highest percentage within soft tissue disease, followed by lichen planus and recurrent apthous ulcers. 4. The number of patients with burning mouth syndrome appeared to be the highest percentage within neuropathic pain.

• Journal of Korean Academy of Nursing
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• v.50 no.2
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• pp.200-209
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• 2020

Purpose: The purpose of this study was to examine the effects of oral gargling with an aromatic solution on xerostomia, objective oral status, and oral health-related quality of life in psychiatric inpatients. Methods: A nonequivalent control group with a non-synchronized design was used in this study. The experimental group (n=34) received oral gargling with an aroma solution, while the control group (n=33) gargled with 0.9% normal saline. Dependent variables were measured at pre-, post-, and follow-up test. Data were analyzed using an χ²-test, Fisher's exact probability test, t-tests, and repeated measures ANOVA using SPSS/WIN v.21.0. Results: After the intervention, significant differences were revealed in xerostomia (F=15.30, p<.001), objective oral status (F=38.44, p<.001), and oral health-related quality of life (F=62.70, p<.001) with an interaction effect between group and time. Conclusion: These findings indicate that gargling with an aroma solution is more effective than 0.9% normal saline for the oral health of psychiatric inpatients. Therefore gargling with an aroma can be safely recommended as a brief, economical, and positive intervention in clinical settings.

• Journal of Korean society of Dental Hygiene
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• v.10 no.6
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• pp.983-990
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• 2010

Objectives : This study was to investigate the level of oral health, xerostomia, and oral health related activities of daily living(ADL) and the clinical factors influencing oral health related quality of life(OHIP-14) in elderly for visiting healthcare. Methods : Data were obtained from a cross-sectional survey of 106 elderly people(mean age=$77.5{\pm}4.98$). Participants in the study were recruited when they attended the public health center in Cheonan-si. Data were collected by means of a personal interview from July 19 through to August 20, 2010. Oral health related ADL, OHIP-14 and dry mouth was measured by the total 24-items. The data was analysed with t-test, one-way ANOVA, and multiple regression using the SPSS program. Results : Participants had a mean of 13.6 remaining natural teeth, which was significantly with age and perceived oral health. Xerostomia score achieved a mean of 6.39 out of a maximum 12 points. Powerful predictors of OHIP-14 were natural teeth, masticatory difficulty, oral pain, PHP index, perceived oral health, age and living together for the elderly Conclusions : Based on the findings, OHIP-14 has a significantly impact on oral health related ADL. These results suggest that elder people oral health promotion should be developed assessment index which was measured predictors related oral health in the elderly for visiting healthcare.

• Journal of Oral Medicine and Pain
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• v.32 no.4
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• pp.365-373
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• 2007

Destruction of oral soft and hard tissues and resulting problems seriously affect the life quality of xerostomic patients. Although artificial saliva is the only regimen for xerostomic patients with totally abolished salivary glands, currently available artificial salivas give restricted satisfaction to patients. The purpose of this study was to contribute to the development of ideal artificial saliva through comparing viscosity and wettability between CMC solutions and human saliva. Commercially-available CMC is dissolved in simulated salivary buffer (SSB) and distilled deionized water (DDW). Various properties of human whole saliva, human glandular saliva, and a CMC-based saliva substitutes known as Salivart and Moi-Stir were compared with those of CMC solutions. Viscosity was measured with a cone-and-plate digital viscometer at six different shear rates, while wettability on acrylic resin and Co-Cr alloy was determined by the contact angle. The obtained results were as follows: 1. The viscosity of CMC solutions was proportional to CMC concentration, with 0.5% CMC solution displaying similar viscosity to stimulated whole saliva. Where as a decrease in contact angle was found with increasing CMC concentration. 2. The viscosity of human saliva was found to be inversely proportional to shear rate, a non-Newtonian (pseudoplastic) trait of biological fluids. The mean viscosity values at various shear rates increased as follows: stimulated parotid saliva, stimulated whole saliva, unstimulated whole saliva, stimulated submandibular-sublingual saliva. 3. Contact angles of human saliva on the tested solid phases were inversely correlated with viscosity, namely decreasing in the order stimulated parotid saliva, stimulated whole saliva, unstimulated whole saliva, stimulated submandibular-sublingual saliva. 4. Boiled CMC dissolved in SSB (CMC-SSB) had a lower viscosity than CMC-SSB (P < 0.01 at shear rate of $90s^{-1}$). 5. For human saliva, contact angles on acrylic resin were significantly lower than those on Co-Cr alloy (P < 0.01). 6. Comparing CMC solutions with human saliva, the contact angles between acrylic resin and human saliva solutions were significantly lower than those between acrylic resin and CMC solutions, including Salivart and Moi-Stir (P <0.01). The effectiveness of CMC solutions in terms of their rheological properties was objectively confirmed, indicating a vital role for CMC in the development of effective salivary substitutes.

• The Journal of the Korea institute of electronic communication sciences
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• v.7 no.5
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• pp.1221-1228
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• 2012

This study was carried out in order to offer basic data for preventing halitosis by understanding about the factors related to self-awareness of halitosis and about the relationship with stress and compulsion targeting students for the Department of Dental Hygiene. As a result of research, the whole subjects were indicated to be 1.76 points for the mean in stress, 1.62 points for the mean in compulsion, and 1.84 points for the mean in self-awareness of halitosis. The group of feeling the tongue to be white and the inside of the mouth to be sticky in own symptom inside the mouth was indicated to be 2.02 points(p=0.000) for stress and 2.00 points(p=0.000) for self-awareness of halitosis. The group of often feeling a sense of oral dryness was indicated to be 2.23 points(p=0.000) for stress, 1.95 points(p=0.000) for compulsion, and 1.89 points(p=0.046) for self-awareness of halitosis. The self-awareness of halitosis stood at r=0.133 with compulsion, thereby having indicated slight positive correlation. Stress and compulsion showed high positive correlation with r=0.425. Accordingly, there is a need of infusing recognition through steady education as a dental hygienist who will have interest in emotional factor along with grasping diverse causes for halitosis, and who will be in charge of a future patients' halitosis.

• Journal of Korean society of Dental Hygiene
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• v.15 no.1
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• pp.55-62
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• 2015

Objectives: The purpose of this study was to investigate the associated factors of self-reported dry mouth in adults. Methods: A self-reported questionnaire was filled out by 249 adults in Seoul and Gyeonggi-do from June to October, 2014. The questionnaire consisted of general characteristics of the subjects, age, monthly income, smoking, alcohol drinking, and systemic diseases including systemic diseases, medication, oral health status, and stress. The question for dry mouth consisted of dryness in skin, eyes, lips, and nasal mucosa. The subjective dry mouth consisted of 6 questions measured by visual analogue scale(VAS). Cronbach's alpha was 0.881 in the study. Oral health related quality of life (OHIP-14) was adapted from Yoon. The questionnaire for OHIP-14 included functional limitation, physical pain, psychological disability, social disability, and experience in hadicap measured by Likert 5 scale. Cronbach's alpha was 0.885 in the study. Data was analyzed for a t-test, one-way ANOVA and multiple regression analysis by using SPSS(SPSS 18.0, USA) program. Results: There were positive correlations between oral health-related quality of life and self-reported dry mouth (functional limitation r=0.288, physical pain r=0.219, psychological discomfort r=0.193, physical disability r=0.280, psychological disability r=0.205, social disability r=0.224 and handicap r=0.270). In the multiple regression analysis, variation of self-reported dry mouth were positively associated with dry eyes{very often(${\beta}=0.305$)), sometimes(${\beta}=0.186$)}, dryness on lips{very often(${\beta}=0.247$), sometimes(${\beta}=0.177$)}, handicap(${\beta}=0.152$), physical disability(${\beta}=0.128$) and alcohol drinking(1-2 times/week)(${\beta}=0.116$) (p<0.001). Conclusions: Self-reported dry mouth may cause deterioration of the entire body dryness(dryness on eyes and lips), low oral health-related quality of life(handicap and physical disability) and alcohol drinking. Thus, It is necessary to develop oral health education programs to prevent and manage dry mouth in adults.