• Title/Summary/Keyword: 괴사성 장염

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S-R variation and Antimicrobial Susceptibility of Clostridium perfringens Isolated from Necrotic Enteritis in Chickens, Enterotoxemia in Piglets and Enterotoxemia in Cattle (닭의 괴사성 장염, 새끼돼지 및 소의 장독혈증에서 분리한 Clostridium perfringens의 S-R 변이와 항균요법제의 감수성)

  • 정희곤
    • The Korean Journal of Food And Nutrition
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    • v.10 no.2
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    • pp.166-173
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    • 1997

  • 1993년부터 1995년까지 약 3개년 동안 우리 나라에서 사육하고 있는 가축의 유병율을 조사한 결과, 닭 16,200수 중에서 54수(0.3%)가 괴사성 장염에 이환 되었으며 새끼돼지 620두 중에서 9두(13.8%)가 장독혈증에 이환 되었다. C. perfringens의 분리율을 조사한 결과, 괴사성 장염에 이환 되어있는 닭 54수 중 7수(13.0%)에서 본균이 분리되었으며 장독혈증에 이환 되어있는 새끼돼지 66두 중 14두(21.2%)에서 본균이 분리되었고 장독혈증에 이환 되어있는 소 9두 중 3두(33.3%)에서 본균이 분리되었다. Acriflavine을 이용하여 C. perfringens의 S-R변이를 조사한 결과, S-R변이는 mercuric chloride, nicotine, caffeine, cysteine, glucose 등의 순으로 나타났는데, 이중 mercuric chloride가 가장 감수성이 높았다. C. perfringens의 항균요법제에 대한 감수성은 cepalothin, penicillin, erythromycin, amikacin 등이 높은 감수성을 나타내었는데, S-R변이 후에는 감수성이 일반적으로 저하되는 경향이었다. 중화시험법을 이용하여 C. perfringens의 독소형을 분류한 결과, cd 24균주 중 22균주(91.7%)는 A형이었으며 2균주(8.3%)는 C형이었다.

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Rotavirus-associated neonatal necrotizing enterocolitis (로타바이러스 감염이 관련된 신생아 괴사성 장염)

  • Seo, Hyun Joo;Jung, Yu Jin;Park, Soo Kyung;Choi, Seo Hui;Lee, Ji Hyuk;Kim, Myo Jing;Chang, Yun Sil;Park, Won Soon
    • Clinical and Experimental Pediatrics
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    • v.52 no.1
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    • pp.56-60
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    • 2009

  • Purpose : This study aimed to test whether rotavirus-associated necrotizing enterocolitis (RV+NEC) produced different clinical findings or outcomes from those of non-rotavirus necrotizing enterocolitis (RV-NEC). Methods : Eight patients from the RV+NEC group and 22 patients from the RV-NEC group diagnosed with modified Bell stage II or higher NEC were selected for this study. Fecal specimens from all infants were tested for rotavirus infection using a monoclonal antibody-based enzyme immunoassay (EIA). Clinical, radiographic, and clinical outcome data were analyzed retrospectively. Results : RV+NEC infants had a significantly higher birth weight and were born at a significantly higher gestational age ($33.5{\pm}3.3$ weeks vs. $29.3{\pm}4.4$ weeks; P=0.01). There were no differences in the occurrence of thrombocytopenia, mural gas, and pneumoperitoneum between the 2 groups. However, portal vein gas was more common in the RV+NEC group (88% vs. 9%; P<0.01). Neither the incidence of Bell stage III (or higher) NEC nor surgical intervention differed between the two groups. The number of complications and mortality rates were also similar. Conclusion : Rotavirus-associated NEC occurs in infants with a higher birth weight and those born at a greater gestational age. However, the severity of the condition and the resulting outcomes did not differ from those for infants affected by non-rotavirus NEC.

  • https://doi.org/10.3345/kjp.2009.52.1.56 인용 PDF KSCI