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The Effects of Preoperative Radiation Therapy in Resectable Rectal Cancer - in view of pathologic aspects - (절제 가능한 직장암에서 수술전 방사선 치료의 효과 -병리 조직학적인 연구를 중심으로-)

  • Choi, Ihl-Bong;Jang-Ji-Young;Kim, In-Ah;Shinn-Kyung-Sub;Lee, Jong-Suh;Chang-Suk-Kyun;Choi, Kyu-Young;Kim, Young-Ha;Kim, Jun-Gi;Chun-Chung-Soo;Kay-Chul-Seung
    • Radiation Oncology Journal
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    • v.15 no.1
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    • pp.49-56
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    • 1997
  • Purpose : To evaluate the pathologic effects of preoperative radiotherapy o the resectable distal rectal cancer, we analyzed the results of postoperative pathologic findings for the patients with preoperative radiotherapy ant surgery Materials and Methods: From July 1995 to April 1996, we treated sixteen patients of resectable rectal cancer with preoperative radiation therapy and curative surgery At diagnosis, Thomas Jefferson (TJ) system was used for the clinical stage of the Patients. We treated the patients with conventional radiation therapy of 4500~5000cGy before surgery. The surgery was carried out 4 weeks after completion of radiation therapy. Modified Astler Coller (MAC) system was used for the postoperative pathologic stage. We analyzed the pathologic stages and findings according to preoperative clinical stage and compared with those of the control group in similar clinical stages. Result : All patients were treated with sphincter preservation surgery after Preoperative radiation therapy. Pathoiogic complete response (CR) was shown in 1 case $(6.3\%)$. We compared the results between preoperative radiation therapy group (Preop.RT group) and surgery only group (control group). In TJ stage II, among nine patients of Preop.RT group, 8 patients $(88.9\%)$ were in MAC stage 8 except 1 CR patient, but among 17 patients of control group. 11 patients$(64.7\%)$ were in MAC stage B and 6 Patients $(35.3\%)$ in MAC stage C. In TJ stage III, among 7 patients of Preop.RT group, 4 patients $(57.1\%)$ were in MAC stage B and 3 patients$(42.9\%)$ in MAC stage C. Among 14 Patients of control group, 4 patients $(28.6\%)$ were in MAC stage B and 10 Patients $(71.4\%)$ in MAC stage C. Above results showed that postoperative Pathologic stage was decreased in Preop.RT group with statistical significance (P=0.049). The postoperative Pathologic findings (blood vessel invasion. Iymphatic vessel invasion, perineural invasion) were decreased in the Preop.RT group compared with those of control group. But statistical significance was found only in Iymphatic vessel invasion (p=0.019). Conclusion : The Postoperative pathologic stages and adverse Prognostic pathologic findings were decreased in preoperative radiation therapy group. The Iymphatic vessel invasion and MAC stage C findings were abruptly decreased in Preoperative radiation therapy group. The preoperative radiation therapy was found to be effective in resectable rectal cancer. The patients group in our study was very small and long term follow up was not done. Therefore, further study about this issues is needed.

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A checklist of vascular plants in limestone areas on the Korean Peninsula (한반도 석회암지대의 관속식물 목록)

  • KIM, Jung-Hyun;NAM, Gi-Heum;LEE, Seung-bae;SHIN, Sookyung;KIM, Jin-Seok
    • Korean Journal of Plant Taxonomy
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    • v.51 no.3
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    • pp.250-293
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    • 2021
  • Limestone areas are sedimentary rock outcrops consisting of calcium carbonate created several hundreds of millions of years ago by calcium-secreting marine organisms and subsequently lifted above sea level by tectonic movement. Limestone areas support very high levels of endemic species of plants and are recognized as biodiversity areas with much biological information. The purpose of this study is to devise a strategy for the comprehensive conservation of the vegetation of limestone areas through analyses of the floristics and plant species compositions in ten limestone areas on the Korean Peninsula. The results of 153 field surveys from April of 2010 to October of 2016 identified 1,202 taxa in total, representing 1,096 species, 18 subspecies, 84 varieties, 2 forms, and 2 hybrids in 530 genera and 133 families. Among them, 55 taxa were endemic plants to Korea, and 38 taxa were red data plants. The floristic target plants amounted to 102 taxa, specifically 27 taxa of grade V and 75 taxa of grade IV. In all, 121 alien plants were recorded in the investigated area. Calciphilous plants amounted to 102 taxa, specifically 14 taxa of calciphilous indicator plants, 30 taxa of superlative most calciphilous plants, and 58 taxa of comparative more calciphilous plants. A cluster analysis showed a high degree of similarity between sites that are geographically adjacent with similar habitat environments. Limestone areas also supported groups distinct from those in non-limestone areas, demonstrating the specificity of limestone flora. Plant geography approaches therefore appear to be crucial to gain a better understanding of the level of biodiversity in limestone areas, not only at the interspecific but also at the intraspecific level. These results highlight the importance of protecting limestone habitats to preserve not only their interspecific but also the intraspecific diversity, which is highly threatened.

전문가심층분석 - FMD 매몰농장 재입식 절차와 청소 및 소독 요령

  • 축산물등급판정소
    • KAPE Magazine
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    • s.176
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    • pp.6-7
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    • 2011
  • 가축 재입식이 시 군의 점검결과에 따라 30일 이후에 입식이 가능해지면서 농가의 손이 바빠질 것으로 보인다. 이번에 수정된 재입식 절차는 가축방역관의 지적상항을 보완하고 문제점이 해결되어야만 재입식이 가능하다. 본고에서는 FMD 매몰 농장 재입식 절차와 청소 소독 요령에 대해 언급하도록 한다.

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정책자료 - 도별 낙농(축산) 지원사업 현황

  • 한국낙농육우협회
    • 월간낙농육우
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    • v.37 no.5
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    • pp.141-150
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    • 2017
  • 협회에서는 중앙정부 및 지자체의 낙농(축산) 지원대책 마련에 활용되면서 우수한 낙농(축산) 지원정책들은 타 지자체와 중앙정부차원에서 균일하게 시행될 수 있도록 참고 건의자료로 활용하기 위해 2017년 도별 낙농(축산) 지원사업 현황을 조사했습니다. 회원농가계서는 해당지역의 지원사업을 확인하시어 목장경영에 참고하시기 바랍니다. 본 내용은 지면관계상 낙농산업과 관련된 부분만 발췌 요약하였으니 보다 자세한 사항은 시 군 축산담당과에 문의하시기 바랍니다.

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산업 - 서울 국제 항공우주 및 방위산업 전시회 2009

  • 한국항공우주산업진흥협회
    • Aerospace Industry
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    • s.104
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    • pp.26-33
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    • 2009
  • "서울 국제 항공우주 및 방위산업 전시회 2009" 행사가 오는 10월 20일부터 25까지 6일간 서울공항(성남 소재)에서 개최될 예정이다. 1995년 첫 행사가 개최된 이래 격년으로 펼쳐지는 이번 전시회는 국내외 인사 및 민 관 군 주요 관계자들이 참석하며, 정부기관 및 자치단체에서 후원하는 범정부적인 행사로 추진 중이다.

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Effects of the Integrative Cognitive Training Program on Elderly Cognitive Function (통합적 인지훈련프로그램의 노인 인지기능에 미치는 효과)

  • Kong, Eun Suk;Kim, Eun-Ju
    • The Journal of the Korea Contents Association
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    • v.14 no.9
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    • pp.332-342
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    • 2014
  • The purpose of this study is to investigate the Effects of the Integrative Cognitive Training Program on Cognitive Function of the community elderly. Nonequivalent control group pretest-posttest design was used. 28 subjects were assigned to each of the group. 24 sessions of the integrative Cognitive Training Program were applied to the experimental group from September to December. The program was provided twice per week for 12weeks, total 24 sessons to the experimental group. Cognition scale for older adults(CSOA) was used to measure cognitive function of the groups before and after the Intervention. The score of Cognition Scale for Older Adults was significantly increased in experimental group than in control group(p< .05). The results of the study that Integrative Cognitive Training Program can be vey useful to improve the cognitive ability for the community elderly.

A Study on Antioxidative Effects of Sipyimiguanjungtang and Osuyubujayijungtang, Korean Traditional Prescriptions for Soum Constitutes, in Brain and Liver of Rat (소음인(少陰人) 십이미관중탕(十二味寬中湯), 오수유부자이중탕(吳茱萸附子理中湯)이 흰쥐의 뇌(腦)와 간조직(肝組織)의 항산화(抗酸化) 기전(機轉)에 미치는 영향(影響))

  • Jung, Bong-yeon;Song, Il-byung
    • Journal of Sasang Constitutional Medicine
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    • v.11 no.2
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    • pp.227-250
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    • 1999
  • The free radical theory of aging was introduced in 1956 by Denham Harman. This aging theory proposed that normal aging results from random deleterious damage to tissues by free radical and supplying antioxidant lead to decrease oxidative damage, inhibit aging process. In this study, we investigated antioxidantive effects of four Korean constitutional prescriptions for 'Soum' constitution - Palmulgunjatang(Y1), Sipyimiguanjungtang(Y2), Osuyubujayijungtang(Y3) and Seungyangyikkibujatang(Y4). Antioxidative activity of this prescriptions was examined by 1,1-diphenyl-2-picrylhyrdazyl radicals, superoxide anion radicals, peroxyl radical, hydroxyl radical scavenging effects and erythrocyte hemolysis inhibitory effects. Y2 and Y3 were shown to have relatively high antioxidative activity on this methods. In additions, result of the cytoprotective effects of Korean constitutional prescriptions agianst 2,2'-azobis(amidinopropane) dihydrochloride (AAPH), a free radical initiator, induced cytotoxcity in human hepatoblastoma cell line was similarly obtained. On the basis of this result, we assayed the antioxidative effects of Y2 and Y3 on experimental oxidative damage, induced in mouse by 100mg/kg AAPH. Male ICR mouse were given oral administration of 500mg/kg Y2 and Y3 for 4 weeks. Thiobarbuturic acid reactive substance (TBARS) and protein degradation level in liver, plasma and brain as index of oxidative damage were decreased and thiol compound, total antioxidant status in plasma were increased by Y2 administration. But, Y3 injected group was decreased only protein degradation level in brain. Also, glutathione, a potent water-soluble endogenous antioxidant, concentration was increased by Y2 and Y3 administration in liver and brain. However, superoxide dismutase and catalase activity as a major antioxidative enzyme in vivo were not shown change by Y2 and Y3 administration. On the basis of these result, Y2 have an antioxidative effects on both water-soluble fraction and lipid-solube fraction in cell and tissues. But, Y3 has a lower antioxidative effects on lipid-soluble fraction than Y2 in cell and tissues. These results suggest that Y2 has a antioxidative effects by protect the tissue against oxygen free radical mediated oxidative damage and Y3 has a limited antioxidaitve effects on water-soluble fraction in vivo. Therefore, we make report that Y2 is more effective prescriptions for anti-aging or therapeutics of diseases.

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Echolocation Call Differences among Local Populations of Greater Horseshoe Bats (Rhinolophus ferrumequinum) (관박쥐 (Rhinolophus ferrumequinum)의 지역개체군 간 반향정위 (Echolocation)의 차이)

  • Jang, Dooly;Kim, Sun-Sook;Yoo, Jeong-Chil
    • Korean Journal of Ecology and Environment
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    • v.49 no.4
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    • pp.385-392
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    • 2016
  • Geographical isolation may lead to the populations having different ecological characteristics. Geographic isolation have been known to cause echolocation call differences in bats. In order to look at geographic differences of echolocation calls of Great Horseshoe Bats (Rhinolophus ferrumequinum), populations of inland and Jeju island habitats were examined in Korea. The study areas were some abandoned mines in the inland and caves of Jeju island, which were known as rest sites of Great Horseshoe Bats during the active season. Recording was done in two ways: Hand-held, Free-flying. Recording pulse was analyzed into five parameters: Maximum Frequency (FMAX), Minimum Frequency (FMIN), Peak Frequency (PF), Duration (D), Inter pulse Interval (IPI). Interestingly, The present study shows that the difference in echolocation between the inland and island populations. The PF of bats inhabited inland was 69 kHz. but, the PF of bats inhabited island (Jeju) was 71 kHz. There was a difference between regions. Discriminant analyses also showed clear difference between the inland and the island populations. Especially, PF of Korea population is lower than that of Europe (82 kHz) and higher than that of Japan (65 kHz).