• Title/Summary/Keyword: 관심농도

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Evaluation of Radioactivity Concentration According to Radioactivity Uptake on Image Acquisition of PET/CT 2D and 3D (PET/CT 2D와 3D 영상 획득에서 방사능 집적에 따른 방사능 농도의 평가)

  • Park, Sun-Myung;Hong, Gun-Chul;Lee, Hyuk;Kim, Ki;Choi, Choon-Ki;Seok, Jae-Dong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.1
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    • pp.111-114
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    • 2010
  • Purpose: There has been recent interest in the radioactivity uptake and image acquisition of radioactivity concentration. The degree of uptake is strongly affected by many factors containing $^{18}F$-FDG injection volume, tumor size and the density of blood glucose. Therefore, we investigated how radioactivity uptake in target influences 2D or 3D image analysis and elucidate radioactivity concentration that mediate this effect. This study will show the relationship between the radioactivity uptake and 2D,3D image acquisition on radioactivity concentration. Materials and Methods: We got image with 2D and 3D using 1994 NEMA PET phantom and GE Discovery(GE, U.S.A) STe 16 PET/CT setting the ratio of background and hot sphere's radioactivity concentration as being a standard of 1:2, 1:4, 1:8, 1:10, 1:20, and 1:30 respectively. And we set 10 minutes for CT attenuation correction and acquisition time. For the reconstruction method, we applied iteration method with twice of the iterative and twenty times subset to both 2D and 3D respectively. For analyzing the images, We set the same ROI at the center of hot sphere and the background radioactivity. We measured the radioactivity count of each part of hot sphere and background, and it was comparative analyzed. Results: The ratio of hot sphere's radioactivity density and the background radioactivity with setting ROI was 1:1.93, 1:3.86, 1:7.79, 1:8.04, 1:18.72, and 1:26.90 in 2D, and 1:1.95, 1:3.71, 1:7.10, 1:7.49, 1:15.10, and 1:23.24 in 3D. The differences of percentage were 3.50%, 3.47%, 8.12%, 8.02%, 10.58%, and 11.06% in 2D, the minimum differentiation was 3.47%, and the maximum one was 11.06%. In 3D, the difference of percentage was 3.66%, 4.80%, 8.38%, 23.92%, 23.86%, and 22.69%. Conclusion: The difference of accumulated concentrations is significantly increased following enhancement of radioactivity concentration. The change of radioactivity density in 2D image is affected by less than 3D. For those reasons, when patient is examined as follow up scan with changing the acquisition mode, scan should be conducted considering those things may affect to the quantitative analysis result and take into account these differences at reading.

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Preparation and Characterization of Jochung, a Grain Syrup, with Onion (옥총(玉葱) 첨가 조청의 제조 및 특성)

  • Kim, D.H.;Kim, Y.B.;Koo, H.J.;Baek, H.J.;Chang, K.J.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.22 no.1
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    • pp.145-152
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    • 2020
  • Onion is a perennial herb of the lily family that has a long history and has long been widely used throughout the world as it is one of the most important condiments in our diet, along with chili peppers and garlic. It has been used for cooking and processing food with its unique flavor and aroma. Because of the nature of onions, long-term storage can lead to spoilage. Research was done to increase profits through processing and expand various onion products. A low temperature extraction method was used to study the physiological activation effect and onion processing method of flavonoid component weak to heat.

Efficient of Hepatobiliary Scintigraphy both Decubitus Position in Biliary Leakage Patients (간담도 스캔 시 담즙 누출(Biliary Leakage)환자에서의 양측와위 자세(Both Decubitus Position)의 유용성)

  • Bahn, Young-Kag;Roh, Dong-Ook;Kang, Chun-Koo;Kim, Jae-Sam;Lee, Chang-Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.12 no.3
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    • pp.229-234
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    • 2008
  • Hepatobiliary scintigraphy is very sensitivity of hepatic cell and gallbladder, biliary track atresia and biliary leakage. however, Hepatobiliary scan of biliary leakage diagnosis was separated determine biliary leakage and bowl drainage bile-juice. The object of this study will determine biliary leakage and bowl drainage bile-juice to hepatobiliary scintigraphy both decubitus position in bile leakage patients. Material & Methode: 31 patients (meal 14, Femeal 17), $51.1{\pm}14.4$ years. dynamic scan acquisition 60 farme for 60 minute on supine position. and delay scan was 2 hrs, 4 hrs, 24 hrs for 5 minute on supine, both decubitus position. Both decubitus position scan was kept for 5 minutes. Efficient of Hepatobiliary Scintigraphy both decubitus position in bile leakage patients was compared leakage size, density, image of supine position and both decubitus position. Results: 23 patients for 31 bile leakage patients was checked up function image or delay image, and 8 patients was checked up bile leakage on both decubitus. anatomical leakage location was supine position very well, but both decubitus position was separated bile leakage and moving bile-juice in bowl. also, uptake (counts/pixel) average of roi and bkg was supine 5.02, left decubitus 2.08, right decubitus 2.68. No. pixels of supine ROI counted 1.91 times than left decubitus, 1.05 times than right decubitus. Conclusion: 31 patient both decubitus position, but decubitus position was separated bile juice movement in bowl leakage location. also, It was compared ROI/BKG ratio and ROI No. pixels of supine, both decubitus in 38.5% patients. And No. pixels of supine position was large 19%, 5% than left decubitus, right decubitus, And density was in low 60%, 50% than left decubitus, right decubitus. It was mean bile leakage of ROI. so, If Hepatobiliary Scintigraphy was additional both decubitus position scan in bile leakage patients, this study will be more valuable in diagnosis of bile leakage.

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Optimum Culture Conditions for the Growth of Spirulina platensis NIES 39 (Spirulina platensis NIES 39의 성장을 위한 최적배양조건)

  • Kim, Young Min;Kim, Mi-Ryung;Kwon, Tae Ho;Ha, Jong-Myung;Lee, Jae-Hwa
    • Applied Chemistry for Engineering
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    • v.20 no.3
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    • pp.285-289
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    • 2009
  • Recently, as the interest in the accelerated global warming and the food shortage problem is increased, the concerns for microalgae as photosynthetic microorganisms are also increased. Specially, photosynthetic microalgae, Spriulina platensis have been an attractive source for $CO_2$ gas fixations and for a vast array of valuable nutritious compounds. In this paper, to culture the microalgal Spirulina platensis NIES 39 in a batch culture with high mass, optimal conditions for the culture temperature, initial pH, light intensity and concentration of carbon and nitrogen, were tested. At the most favorable culture condition, $35^{\circ}C$, initial pH 9.5, 4500 lux and carbon and nitrogen concentration of 16.8 g/L $NaHCO_3$ and 2.5 g/L $NaNO_3$, the excellent yields of 2.10 g/L biomass and 29.53 mg/L chlorophyll were obtained.

Smoking-Induced Dopamine Release Studied with $[^{11}C]Raclopride$ PET ($[^{11}C]Raclopride$ PET을 이용한 흡연에 의한 도파민 유리 영상 연구)

  • Kim, Yu-Kyeong;Cho, Sang-Soo;Lee, Do-Hoon;Ryu, Hye-Jung;Lee, Eun-Ju;Ryu, Chang-Hung;Jeong, In-Soon;Hong, Soo-Kyung;Lee, Jae-Sung;Seo, Hong-Gwan;Jeong, Jae-Min;Lee, Won-Woo;Kim, Sang-Eun
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.6
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    • pp.421-429
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    • 2005
  • Purpose: It has been postulated that dopamine release in the striatum underlies the reinforcing properties of nicotine. Substantial evidence in the animal studies demonstrates that nicotine interacts with dopaminergic neuron and regulates the activation of the dopaminergic system. The aim of this study was to visualize the dopamine release by smoking in human brain using PET scan with $[^{11}C]raclopride$. Materials and Methods: Five male non-smokers or ex-smokers with an abstinence period longer than 1 year (mean age of $24.4{\pm}1.7$ years) were enrolled in this study $[^{11}C]raclopride$, a dopamine D2 receptor radioligand, was administrated with bolus-plus-constant infusion. Dynamic PET was performed during 120 minutes ($3{\times}20s,\;2{\times}60s,\;2{\times}120s,\;1{\times}180s\;and\;22{\times}300s$). following the 50 minute-scanning, subjects smoked a cigarette containing 1 mg of nicotine while in the scanner. Blood samples for the measurement of plasma nicotine level were collected at 0, 5, 10, 15, 20, 25, 30, 45, 60, and 90 minute after smoking. Regions for striatal structures were drawn on the coronal summed PET images guided with co-registered MRI. Binding potential, calculated as (striatal-cerebellar)/cerebellar activity, was measured under equilibrium condition at baseline and smoking session. Results: The mean decrease in binding potential of $[^{11}C]raclopride$ between the baseline and smoking in caudate head, anterior putamen and ventral striatum was 4.7%, 4.0% and 7.8%, respectively. This indicated the striatal dopamine release by smoking. Of these, the reduction in binding potential in the ventral striatum was significantly correlated with the cumulated plasma level of the nicotine (Spearman's rho=0.9, p=0.04). Conclusion: These data demonstrate that in vivo imaging with $[^{11}C]raclopride$ PET could measure nicotine-induced dopamine release in the human brain, which has a significant positive correlation with the amount or nicotine administered bt smoking.

Association Study between Serum Uric Acid Level and Metabolic Syndrome (혈청 요산 농도와 대사증후군과의 연관성에 대한 연구)

  • Park, Duk-Hyun;Lee, Eun-Ryeong;Ju, Joung-Youl
    • The Journal of the Korea Contents Association
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    • v.17 no.2
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    • pp.38-46
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    • 2017
  • This research aimed to identify the correlation between the metabolic syndrome, which is one of the cardiovascular risk factors and emerging as an issue in the society, and the serum uric acid level. The research was conducted on a total of 1,444 patients who took a medical examination at a health examination center. The research subjects were composed of 977 men and 467 women. By conducting physical measurement and the blood test on the subjects, the research identified the correlation between the serum uric acid level and the metabolic syndrome and compared the number of the risk factors by dividing the class of the serum uric acid. The average level of serum uric acid was identified higher in men at $6.30{\pm}1.39mg/dL$ than $4.43{\pm}0.89mg/dL$ in women. Men had a correlation between age, waist size, systolic blood pressure, neutral fat, HDL-cholesterol, WBC count and ESR and the serum uric acid level (p<0.05), while women had a correlation between waist size, diastolic blood pressure level, neutral fat, HDL-cholesterol and ESR and the serum uric acid level (p<0.05). The number of the risk factors depending on the serum uric acid level increased as the serum uric acid level rose. The overall prevalence rate of the metabolic syndrome was higher in men at 17.4% than 10.2% in women. This showed that there is a statistically relevant relevance between the metabolic syndrome and the serum uric acid level, and the number of the risk factors of the metabolic syndrome will go up with an increase in the serum uric acid level.

Zn-Sn-O비정질 산화물 반도체 박막의 Ga 첨가 영향

  • Kim, Hye-Ri;Song, Pung-Geun;Kim, Dong-Ho
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2011.05a
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    • pp.61.2-61.2
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    • 2011
  • 넓은 밴드갭을 가지고 있어 가시광에서 투명하며 높은 이동도를 가진 산화물 반도체는 기존의 Si 기반 TFT 소자를 대체할 차세대 디스플레이의 핵심 소재기술로 관심이 높아지고 있다. 그러나 대표적인 산화물 반도체인 In-Ga-Zn-O (IGZO)에 포함된 인듐의 수요 증가에 따른 가격 급등 문제로 이를 대체할 수 있는 새로운 산화물 반도체 재료에 대한 연구의 필요성이 대두되고 있다. 이에 비교적 저가의 물질로 구성된 Zn-Sn-O계 산화물 소재에 대한 연구가 진행된 바 있으나, 높은 수준의 캐리어 농도를 가지고 있어 TFT 채널용 반도체소재로 적용되기 위해서는 이를 $10^{17}\;cm^{-3}$ 이하로 조절할 수 있는 기술개발이 요구된다. 본 연구는 마그네트론 스퍼터링법을 이용하여 증착된 Ga-Zn-Sn-O (GZTO) 박막의 갈륨 첨가에 따른 특성변화를 조사하였다. GZO ($Ga_2O_3$ 5wt%)와 $SnO_2$ 타켓의 인가 파워를 고정한 상태에서 $Ga_2O_3$ 타켓의 인가 파워를 0~100W로 조절하여 박막 내 Ga 함량을 증가시켰다. 제조된 모든 GZTO 박막은 Ga함량에 관계없이 비정질 구조를 가지며 가시광 영역에서 약 78%의 우수한 투과율을 나타낸다. Ga 함량에 따라 박막의 구조적, 광학적 특성은 크게 변하지 않지만 전기적 특성은 뚜렷한 변화를 나타냈다. $Ga_2O_3$ 파워가 증가할수록 박막 내 캐리어 농도와 이동도의 감소로 비저항이 크게 증가하는데 특히 캐리어 농도는 $Ga_2O_3$ 파워가 0에서 100W로 증가할 때 $2{\times}10^{18}$에서 $8{\times}10^{14}\;cm^{-3}$으로 감소하였다. 이는 Ga-O의 화학적 결합 에너지가 다른 원소들(Zn 또는 In)에 비해 커서 박막 내 산소공공의 감소가 야기되었기 때문이다. 이러한 전기물성의 변화를 이해하기 위해 XPS 분석을 수행하였다. 제조된 GZTO 박막은 $Ga_2O_3$ 파워가 증가함에 따라 O 1s peak에서 산소공공과 관련된 530.8 eV peak의 intensity가 감소한다. 따라서 Ga을 첨가에 따른 캐리어 농도의 감소는 산소공공의 발생억제로 기인한 것으로 판단되며, 본 연구결과는 ZTO계 비정질 산화물 반도체의 활용가능성을 제시하였다.

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해양 심층수 첨가에 따른 알콜발효 효모의 증식 변화

  • 김미림;정지숙;이기동
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.04a
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    • pp.147-148
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    • 2003
  • 최근 새로운 바다 자원으로서 “해양 심층수”가 주목받고 있다. 해양 심층수(深層水, deep sea water)는 태양광이 도달하지 않는 수심 200 m 이상 깊이의 물로 수온이 2$^{\circ}C$ 이하로 연중 거의 변화가 없는 저온안정성과 무기 영양염을 다량 포함하는 특징이 있어 심층수의 활용도는 매우 높다. NaCl만 제거하면 훌릉한 생수가 되기 때문에 심층수를 원료로 한 식품, 화장품, 의약품 개발에 대한 관심이 높아지고 있다. 미국, 일본 등지에서는 10여년전부터 심층수를 이용한 에너지, 수자원, 생수 및 식품 산업이 활발히 진행되어졌다. 현재 식품 산업분야로는 두부제조, 빵, 청주, 간장, 된장 등의 발효식품에 대한 연구가 진행되어지고 있다. 심층수를 적당하게 첨가하면 알코올 농도가 높아지는 발효강화작용이 있다. 새로운 건강 먹거리를 갈망하는 현대인들에게 해양 심층수를 이용한 발효식품은 매우 환영받을 것으로 사료된다. 이에 본 연구는 해양 심층수의 다양한 자원성을 효율적으로 활용하기 위해 심층수의 청정성과 풍부한 미네랄을 함유한 심층수의 농도에 따른 효모의 증식도를 알아봄으로서 적응력 강한 효모를 조사하였다. 실험에 사용한 해양 심층수는 淸凉飮料水(日本ナチュラルヘルス株式會社, 深透水 1550) 사용하였다. 효모균주는 경북과학대 전통식품 연구소에서 보유하고 있는 9종의 효모를 사용하였으며, 심층수 경도 250, 500, 1000의 심층수와 1차 증류수(대조군)에 sucrose 10% 첨가한 당용액을 사용하였다. 또한 당의 적응력을 알아보기 위해 sucrose 10, 15, 20% 첨가 당용액을 사용하여 Sacch.cerevisiae kluyvery DJ97 효모의 증식도를 알아보았다. 그 결과, Saccharomyces cerevisiae 12호 균주가 심층수 경도 500인 시험군에서 증식력이 높았으며, Saccharomyces cerevisiae 901 균주는 경도 1000인 시험군이 대조군에 비해 증식력이 높게 나타나 효모균주의 종류와 심층수의 첨가량에 따라 적응력이 차이가 있었다. 당농도와 심층수 첨가량에 따른 효모 균주의 발효력을 알아본 결과 심층수 경도 200의 당 10% 첨가군에서 가장 잘 증식하는 것으로 나타나, 알코을 효모균주의 발효력을 높이는데는 최적의 농도가 있음을 알 수 있었다. 따라서 심층수를 이용한 다양한 발효식품에 대한 연구가 요구되어진다.

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Effect of Electrolytic Condition on Composition of Zn-Co Alloy Plating (Zn-Co 합금도금의 조성에 미치는 전해조건의 영향)

  • Kang, Soo Young
    • Journal of the Korea Convergence Society
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    • v.8 no.11
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    • pp.287-292
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    • 2017
  • The electrodeposition of Zn on the automotive parts has been adapted However, because Zn electrodeposit needs to increase thickness for corrosion protection, it has problem of destruction of electrodeposit Zn-based electrodeposit have teen studied for corrosion protection and decreasing electrodeposit thickness. Especially; Zn-Co electrodeposit have much attention In this study, the Composition of Zn-Co electrodeposit in various manufacturing condition such as temperature, current density and electrolyte content was investigated to understand effect of electrolysis condition on Co content of specimen. The results were explained by cathode overvoltage and diffusion coefficient. As the current density increases, the electrolyte temperature decreases, and as the electrolyte concentration decreases, the overvoltage of the cathode increases. As the overvoltage of the cathode increases, the concentration polarization becomes more important than the activation polarization. Concentration polarization is determined by the diffusion of the mass transfer in the diffusion layer. In a constant concentration polarization, a large amount of elements with a large diffusion coefficient is diffused. That is, as the overvoltage of the cathode increases, the Zn content having a large diffusion coefficient increases.

Comparison of three analytical methods for PCBs-containing liquid wastes (폴리염화비페닐류 함유 액상폐기물 시험방법별 분석결과 비교)

  • Kim, Kyeo-Keun;Yoon, Seong-Kyu;Bae, Woo-Keun
    • Analytical Science and Technology
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    • v.23 no.3
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    • pp.278-283
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    • 2010
  • This study was performed to compare the analytical results among L2000DX and two GC/ECD methods (rapid and conventional). 15 samples of transformer oils were collected to compare the analytical results. In the analytical results of PCBs-containing transformer oil, the PCBs concentrations were in the range of 4.4 mg/L to 182.8 mg/L with L2000DX, N.D. to 14.63 mg/L with conventional GC/ECD, and N.D. to 13.03 mg/L using rapid GC/ECD. The PCB concentrations detected with the L2000DX showed a large difference to those detected with GC/ECD methods. Otherwise, little difference was shown between the two GC/ECD methods at a concentration range lower than 4 mg/L, although the rapid GC/ECD method tended to detect a slightly lower concentration near the regulation criteria of Korea for 2 mg/L.