• Journal of the Korean Society of Radiology
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• v.5 no.6
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• pp.309-313
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• 2011

It is necessary for patients to wait twice for the thyroid examination of thyroid uptake measurement and thyroid scan by using $^{99m}Tc$-pertechnetate. In the study, a method of simultaneous examination of thyroid uptake measurement and thyroid scan by one intravenous injection of $^{99m}Tc$-pertechnetate was suggested by using attenuation filter. As a result, there was a significant correlation between control group and experimental group according to existence of attenuation filter. Consequently, the simultaneous examination of thyroid uptake measurement and thyroid scan by one intravenous injection can be applied clinically.

• Journal of the Korean Society of Radiology
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• v.15 no.4
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• pp.533-538
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• 2021

^99mTcO₄^- is used to measure thyroid uptake. When measuring background radioactivity of the thigh, the distance between the detector and the thigh was 20 cm at a position 10 cm above the knee from the knee to the pelvis. At 25 cm, many hospitals are measuring at different distances. The purpose of this study was to study the difference in effectiveness in obtaining the thyroid uptake rate by quantitatively analyzing the uptake rate measurement at two distances. As a result, the average thyroid uptake rate measured at 20 cm in the thigh of 50 patients was 3.532±4.312%, and the average thyroid uptake rate measured at 25 cm was 3.680±4.304%. As a result of the thyroid uptake rate test result, the femoral background radioactivity value measured at a distance of 20 cm was relatively higher than the background radioactivity value measured at a distance of 25 cm, and as a result, the thyroid uptake rate was 0.148% lower.

• The Korean Journal of Nuclear Medicine
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• v.37 no.2
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• pp.135-136
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• 2003

A 43-year-old woman with diabetic nephropathy underwent a Tc-99m MAG3 renal scintigraphy for the evaluation of renal function. Posterior images at 60 minutes demonstrated a migration of radiotracer activity beyond the lower pole of the left kidney, which might be incorrectly interpreted as urine leaks. However, the increased activities were moving along the bowel lumens over time. Another ring-like radioactivity was also seen in the suprasplenic region, and increased with time. These radioactivities were in the gastric fundus and gastrointestinal tract and caused by free Tc-99m pertechnetate.

• Journal of the Korean Society of Radiology
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• v.9 no.6
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• pp.357-362
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• 2015

This study was to evaluate the usefulness through the comparison of patients group and healthy control group by acquiring a variety of functional parameters index from time-activity curves of salivary gland scan using 99mTc-pertechnetate. From December 2014 to February 2015, had the targets of 30 patients with dry mouth and 10 people in healthy control group underwent the salivary gland scan. After intravenous injection of 370 MBq of 99mTc-pertechnetate, Vitamin C powder stimulation was administerd orally at 20 min and then 10 minutes were taken scan. The method of quantitative analysis was as follows, the time-activity curve was drawn after the parotid gland and submandible gland were prescribed as a region of interest, a variety of function parameters index was obtained in each position of the curve, and the patients group and the control group were compared. As for the methods applied in comparison and measurement, uptake ratio (UR), time at maximum counts (Tmax), time at minimum counts (Tmin), maximum accumulation (MA), accumulation velocity, maximum secretion (MS), maximum stimulation secretion (MSS), and secretion velocity (SV) were used. In the comparison of functional parameters index of patient group and normal group, the healthy normal group showed significant difference compared to the patient group in all indices except for the minimum radioactivity time (Tmin), and also in terms of variation over time the normal group showed significant difference compared to the patient group (p<0.05). Consequently, it was considered that the quantitative analysis that used a variety of function parameters index would be useful for evaluating the function of the salivary glands of the patients with dry mouth as an objective and standardized information.

• The Korean Journal of Nuclear Medicine Technology
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• v.19 no.2
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• pp.81-86
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• 2015

Purpose This study was to evaluate the usefulness through the comparison of patients group and healthy control group by acquiring a variety of functional parameters index from time-activity curves of salivary gland scintigraphy using $^{99m}Tc$. Materials and Methods From December 2014 to February 2015 with the targets of 30 patients in the patient group who presented themselves with xerostomia and underwent the salivary gland scan and 10 people in healthy control group, approximately 30 minutes of dynamic Scan was carried out after the intravenous bolus injection of 370 MBq of $^{99m}TcO_4{^-}$ and per os stimulation with Vitamin C powder 20 minutes after the injection. The method of quantitative analysis was as follows, the time-activity curve was drawn after the parotid gland and submandible gland were prescribed as a region of interest, a variety of functional parameters index was obtained in each position of the curve, and the patients group and the control group were compared. Results As for the methods applied in comparison and measurement, uptake ratio (UR), time at maximum counts (Tmax), time at minimum counts (Tmin), maximum accumulation (MA), accumulation velocity, maximum secretion (MS), maximum stimulation secretion (MSS), and secretion velocity (SV) were used. In the comparison of functional parameters index of patient group and normal group, the healthy normal group showed significant difference compared to the patient group in all indices except for the minimum radioactivity time (Tmin), and also in terms of variation over time the normal group showed significant difference compared to the patient group (p<0.05). Conclusion Consequently, it was considered that the quantitative analysis that used a variety of functional parameters index would be useful for evaluating the function of the salivary glands of the patients with xerostomia as an objective and standardized information.

• The Korean Journal of Nuclear Medicine Technology
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• v.23 no.2
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• pp.13-19
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• 2019

Purpose Tc-99m HMPAO is widely used radiopharmaceutical for brain perfusion SPECT. Tc-99m HMPAO is chemically unstable and is liable to show deterioration of labeling efficiency due to high incidence of secondary Tc-99m HMPAO complex, free pertechnetate and reduced-hydrolyzed Tc-99m. In this study, we investigated whether sialogogues administration could reduce the impurities of Tc-99m HMPAO. Materials and Methods In thirty subjects(20 male and 10 female, age range 19~89 years, mean age $60.7{\pm}14.5years$), brain perfusion SPECT were performed at basal and citric acid stimulation states consecutively after injection of 555 MBq of Tc-99m HMPAO. In the salivary glands, the uptake coefficient was calculated using Siemens processing program. Statistical comparison between before and after the citric acid stimulation performed paired t-test. P value less than 0.05 was regarded as statistically significant. Results Salivary glands uptake was $12900{\pm}3101$ counts in basal and $10677{\pm}2742$ counts in citric acid stimulation states. Unnecessary impurities in the body is much decreased after citric acid administration(t=10.78, P<0.05). The image quality was much improved after administration of citric acid and the regional cerebral perfusion was clearly from demarcated the background. Conclusion The impurity is distributed throughout the body particularly in the salivary glands and nasal mucosa when Tc-99m HMPAO brain perfusion SPECT is performed. If this impurities is not removed, the quality of the image may deteriorate, resulting in errors in visual evaluation. The use of sialogogues could be helpful for decreasing unnecessary impurities in the body.