• Title/Summary/Keyword: 공학수학(공업수학)

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Preparation and Drug Release Properties of Naproxen Imprinted Biodegradable Polymers Based Multi-Layer Biomaterials (나프록센이 각인된 생분해성 고분자 기반 다층 바이오소재의 제조 및 약물 방출 특성)

  • Eun-Bi Cho;Han-Seong Kim;Min‑Jin Hwang;Soon-Do Yoon
    • Applied Chemistry for Engineering
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    • v.34 no.2
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    • pp.161-169
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    • 2023
  • In this study, we prepared naproxen (NP) imprinted biodegradable polymer based multi-layer biomaterials using allbanggae starch (ABS), polyvinyl alcohol (PVA), and alginic acid (SA), and investigated their physicochemical properties and the controlled drug release effects. In addition, the prepared multi-layer biomaterials were characterized by FE-SEM and FT-IR. In order to confirm the controlled drug release effect for the transdermal drug delivery system (TDDS), the NP release properties of NP imprinted multi-layer biomaterials were investigated using various pH buffer solutions and artificial skin at 36.5 ℃. The results of NP release in various pH buffer solutions indicated that the NP release at high pH was about 1.3 times faster than that at low pH. In addition, NP release in multi-layer biomaterials was about 4.0 times slower than that in single-layer biomaterials. It was confirmed that the NP release rate in triple-layer biomaterials was 4.0 times slower than that in single-layer biomaterials while using artificial skin. Also, it could be found that NP in double-layer biomaterials and triple-layer biomaterials was released sustainably for 12 h. The NP release mechanism in pH buffer solutions followed the Fickian diffusion mechanism, but followed the non-Fickian diffusion mechanism with artificial skin.

A Study on the Educational Needs and the Review of the Validity of the Establishment for Invention Gifted School (발명영재학교의 교육수요 진단 및 설립 타당성 검토 연구)

  • Choi, Yu-Hyun;Kang, Kyoung-Kyoon;Shim, Jae-Young;Lee, Han-Gyu;Chung, Ho-Keun;Lee, Jin-Woo
    • 대한공업교육학회지
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    • v.33 no.1
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    • pp.169-190
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    • 2008
  • The purposes of this research were to review the validity and to investigated educational needs of the establishment for invention gifted school. And this study was conducted on the establishment plan through diagnosis necessity and validity of the establishment for invention gifted school. The methodes of this study were review, investigation researches, workshop, expert review for validity and a seminar. The results was as follows: First, the invention gifted school presented distinctive curriculum and instruction methods. The curriculum focus on engineering, technology, invention, problem solving, and STEM. And it presented scenario on the establishment of invention gifted school from the viewpoint of necessity and distinction. Second, the invention gifted school investigated high-level transition from demand of education of students and their parents. Third, the necessity level was higher than the validity and feasibility with expert assessment. But, before the establishment of the invention gifted school institute will review pre-requirements and hinder factors.

Optimization for Decolorization and UV-Absorbility of Refined Sea Buckthorn Oil Using CCD-RSM (CCD-RSM을 이용한 시벅턴 오일의 탈색공정 최적화 및 자외선 흡수능력 평가)

  • Hong, Seheum;Zheng, Yunfei;Lee, Seung Bum
    • Applied Chemistry for Engineering
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    • v.32 no.1
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    • pp.61-67
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    • 2021
  • In this study, the adsorption decolorization process of sea buckthorn oil was carried out to verify the possibility of the sea buckthorn oil as a natural UV absorber. The optimization was carried out by using the central composite design model-response surface methodology (CCD-RSM). The response values of CCD-RSM were selected as the decolorization effect through the process, acid value after decolorization, and UV absorbance of the decolored oil at 290nm. The amount of adsorbent, temperature and time were selected as the process variables for the experiments. According to the results of CCD-RSM, the results of optimization were all consistent. The optimal conditions, which satisfy CCD-RSM statically and mathematically, were 4.32 wt.%, 134.90 ℃, and 19.8 min for the amount of adsorbent, temperature and time, respectively. The estimated response values expected under these optimal conditions values were 94.78%, 2.08 mg/g KOH, and 2.91 for the decolorization effect, acid value and UV absorbance at 290 nm, respectively. Also the average error from actual experiment for verifying the conclusions was smaller than 2%. Therefore, it was confirmed that the application of CCD-RSM to the adsorption decolorization process of sea buckthorn oil showed a very high level of acceptable results and that the sea buckthorn oil has high possibility to be used as a natural UV absorber.

The Development and Application of Activity-Centered STEM Education Program of Electricity, Electronics Technology area in Middle School (중학교 전기전자기술 영역의 활동 중심 STEM 교육프로그램 개발 및 적용)

  • Bae, Seon-A
    • 대한공업교육학회지
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    • v.36 no.1
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    • pp.1-22
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    • 2011
  • The purpose of this study was to develop and apply activity-centered STEM education program of electricity and electronics technology are in middle schools. The program was developed on the emphasis of problem solving in real world in relation to knowledge, attitude, and skill of Science, Technology, Engineering, and Mathematics. Basically the activity-centered STEM education program was developed through three steps of preparation, development and improvement. In the preparation stage the fellowing was included: (1) need analysis of student, educator, society (2) selection of integration type (3) analyzing subject matter of electricity, electronics area (4) establishing criteria for selecting activity tasks. In the development stage the fellowing was conducted: (1) selection of activity tasks (2) setting up educational goals (3) analyzing activity and clarifing the detailed activity (4) selecting program content, (5) organization of instructional content (6) statement of instructional objectives (7) structuring STEM education program In the improvement stage the fellowing was consisted of: (1) verification of validity by experts (2) execution of pilot test and field test by students and correction of program. The results of the applied the Activity-Based STEM Education Program to 'Afterschool' activities of S middle school were as follow: First, student' satisfaction level was high. Second, student' achievement in the cognitive domain, and affective domain was positive change. Third, student' problem solving ability was positive effect.

Unsteady Free Convection Flow in Horizontal Channels with Arbitrary Wall Temperatures (임의의 벽면온도에 따른 수평채널에서의 비정상 자연대류운동)

  • Im, Goeng
    • The Journal of Engineering Research
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    • v.1 no.1
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    • pp.23-30
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    • 1997
  • Energy transfer by free convection arises in many engineering applications, such as a hot steam radiator for heating a room, refrigeration coils, electric transformers, heating elements and electronic equipments. Generally unsteady natural convection flow in a horizontal channel with arbitrary wall temperatures and the mathematical and physical basis of convection transport has been considered in general. A physically meaningful exact solution of the problem has been obtained in a closed form by the application of the standard finite sine transform technique. Influences of the governing parameters, the Prandtl number and the Rayleigh number, to bring the flow and heat transfer to final steady states have been discussed separately. For constant values of the arbitray wall temperatures and of the function, determining the average axial velocity, the final steady state is approached in different times respectively for the cases when the Prandtl number Pr>1 and Pr<1. It is also seen that the function, representing the axial temperature gradient, is influenced by none of the governing parameters : but the steady state flow is influenced only by the Rayleigh number. There are, of course, many applications. Free convection strongly influences heat transfer from pipes and transmission lines, as well as from various electronic devices. It is also relevant to the environmental sciences, where it is responsible for oceanic and atmospheric motions, as well as related heat transfer processes.

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Water and Wastewater Minimization Technology Through Process Water-Reusing Optimization (공정용수 재이용 최적화를 통한 용수 및 폐수 최소화 기술)

  • Yoo, Chang-Kyoo;Lee, Tae-Yeong;Lee, In-Beum
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.9
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    • pp.961-976
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    • 2006
  • Designing water-reuse network which can reduce the fresh water within the process and increase the water-use efficiency by scientific and systematic analysis is recently interested in the industries. Water systems often allow efficient water uses via water reuse and recirculation in the paper, petrochemical, and steel industries which necessitate a lot of freshwater within the process. Defining network layout connecting water-using process is frequently accomplished by using water pinch technology which optimizes freshwater entering the process and also reduces the wastewater. In this review, recent researches and case studies of water pinch technology which can find the bottleneck of the water stream at the water reuse designing stage are introduced. Necessity of water pinch technology is illustrated by examples of real industries. Recent studies on simultaneous energy and water minimization and water-reuse network among industries in eco-industrial park(EIP) are also introduced.