• Title/Summary/Keyword: 골량

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웃음 꽃피우는 협회 - 그래픽 건강 뉴스 - 2010년 한국건강관리협회 골다공증 검사결과 골다공증 작은 충격에도 골절 부른다

  • 한국건강관리협회
    • 건강소식
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    • v.36 no.1
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    • pp.40-41
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    • 2012

  • 골다공증은 뼈의 화학적 조성에는 변화가 없고 단위 용적 내의 물량 감소를 초래해 경미한 충격에도 쉽게 골절을 일으키는 질환으로 뼛속에 구멍이 많아져 골밀도가 저하된 상태를 말한다. 우리 몸의 뼈는 소아기와 청소년기를 거쳐서 점차 단단해지고 20~30대에 생애 중 최대골량을 형성하며, 나이가 들수록 골량이 서서히 줄어들다가 폐경기 이후 여성에서 매우 빠른 속도로 골량이 감소한다. 이러한 골다공증은 대부분 증상 없이 조용히 진행되다가 골절이 나타난 후에야 발견된다. 골다공증이 진행된 후에는 허리가 구부러지고 경미한 충격에도 골절을 일으키는데 주로 척추, 대퇴골 늑글 등의 골절이 흔히 발생한다.

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Association of Bone Mineral Density with the Metabolic Syndrome (건강검진 수진자들에서 골밀도와 대사증후군의 연관성)

  • Kang, Yeong-Han;Kam, Shin
    • Journal of radiological science and technology
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    • v.31 no.3
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    • pp.259-266
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    • 2008

  • Objective : The purpose of this study was to examine the relationship between bone mineral density (BMD) and the metabolic syndrome. Method : We conducted a cross-sectional study of 1204 adults(males: 364 females: 840) in a general hospital health promotion center. They were grouped into the normal and lower BMD group according to bone loss(osteopenia, osteoporosis), as determined by duel energy X-ray absorptiometery(DEXA). We analyzed the association between BMD and metabolic syndrome by multiple logistic regression analysis. After adjustment for age, weight, alcohol intake, smoking, regular exercise, regular intake of meals, and menopausal status, odds ratios for the prevalence of the metabolic syndrome by gender were calculated for lower BMD. Results : After adjustment for the effect of potential covariates, the prevalence of metabolic syndrome was associated with bone loss in men(p<0.001). If the odds ratio of normal group is 1.00, then that of the lower BMD group is 3.07(95% CI=1.83-5.16). The prevalence of metabolic alterations fitting the criteria of metabolic syndrome was significantly decreased in High BMI, Low HDL in men and in High BMI in women(p<0.05). Conclusions : This study shows that BMD was associated with metabolic syndrome. Further studies needed to obtain evidence concerning the association between BMD and metabolic syndrome.

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Predicting the Role of Osteal Macrophages and Osteocytes in Bone Tissue Network Using a Mathematical Modeling (수학적 모델링을 이용한 골조직 세포 네트워크에서 Osteal Macrophage와 골세포의 역할 예측)

  • Hwang, Soo-Jeong
    • Journal of dental hygiene science
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    • v.18 no.2
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    • pp.130-135
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    • 2018

  • The aim of this study was to investigate the role of osteal macrophages (osteomac) and osteocytes in bone remodeling using a mathematical model. We constructed the bone system with pre-osteoblasts, osteoclasts, osteocytes, and osteomac. Each link of the parameters and ordinary differential equations followed the Graham's model in 2013 except for the parameters of osteomac signaling and osteocytes signaling to link preosteoblasts and osteoblasts. We simulated the changes in each cell and bone volume according to the changes in the parameters of osteomac signaling and osteocytes signaling. The results showed bone volume was unstable and decreased gradually when the effectiveness of osteocytes and osteomac dropped below a certain level. When the parameters of osteomac signaling and osteocytes signaling to link preosteoblasts and osteoblasts had a value less than 1, bone volume increased with the increase in the parameter of osteomac signaling to link preosteoblasts and osteoblasts. Moreover, although the parameter of osteocytes signaling to link preosteoblasts and osteoblasts, increased in case of a small parameter of osteomac signaling, bone volulme decreased. If the parameters of osteomac signaling to link preosteoblasts and osteoblasts were over a certain level, bone volume was positively maintained, despite the parameter of osteocyte signaling to link preosteoblasts and osteoblasts. We suggested the osteomac may affect bone remodeling and may play an important role in bone cell network.

  • https://doi.org/10.17135/jdhs.2018.18.2.130 인용 PDF KSCI

어르신들을 괴롭히는 골다공증

  • Kim, Je-Uk
    • 건강소식
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    • v.32 no.4 s.353
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    • pp.28-29
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    • 2008

  • 여러분은 나이가 드신 할머니, 할아버지들이 허리가 구부러지고 팔, 다리, 허리 등이 아프다고 하시거나, 가볍게 넘어졌을 뿐인데 뼈가 부러지는 경우를 본 적이 있을 것이다. 예전에는 이런 증상을 자연적인 현상으로 생각하거나 재수가 없어서 우연히 생긴 것으로 생각하는 경우가 많았다. 그러나 사실은 뼈에 구멍이 많아지고 약해지는 골다공증이라는 질병 탓이다. 골다공증이란 골량이 현저히 감소하여 뼈가 체중이나기계적인 압력에 견디는 힘이 약해지고 실내에서 가볍게 넘어지는 것 등의 미약한 충격에도 골절이 생길수 있는 질환을 말한다.

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