• Title/Summary/Keyword: 고창군

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$^{99m}Tc$-Glucarate Uptake in Ischemic Tissue of Experimental Models of Cerebral Ischemia (실험적 뇌허혈증 모델에서 허혈 조직의 $^{99m}Tc$-glucarate 섭취)

  • Jeong, Jae-Min;Kim, Young-Ju;Choi, Seok-Rye;Kim, Chae-Kyun;Mar, Woong-Chun;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon;Lee, Dong-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.30 no.4
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    • pp.484-492
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    • 1996
  • To detect ischemic tissue in experimental model of cerebral ischemia made by middle cerebral artery(MCA)-occlusion, we acquired triple image of $^{99m}Tc$-glucarate, [$^{18}F$]fluoro-deoxyglucose (FDG), and 2,3,5- triphenyltetrazolium (TTC) staining. We made cerebral infarction either with reperfusion (after occlusion of 2 hours) or without reperfusion in 10 Sprague-Dawley rats by inserting thread to MCA through internal carotid artery. After 22 hours, we injected 740 MBq of $^{99m}Tc$-glucarate and 55.5 MBq of [$^{18}F$]FDG through tail vein. Each 1 mm slice of rat brains was frozen and exposed to imaging plate for 20 minutes in freezer to get an [$^{18}F$]FDG image. After 20 hours enough to fade radioactivity of [$^{18}F$]FDG, the slices were again imaged by BAS1500 for $^{99m}Tc$-glucarate uptake. Finally, these brain tissues were stained with TTC. Semi-quantitative visual analysis was done by grading 0 to 3 points according to the degree of uptakes($^{99m}Tc$-glucarate) and decreased uptakes([$^{18}F$]FDG and TTC). Ten rats survived with neurologic symptoms. TTC staining confirmed the development of infarction. The size of the infarction was relatively larger in the group without reperfusion. [$^{18}F$]FDG images were similar to TTC-stained images. However, we found regions with intermediate uptake which were not stained with TTC. We found regions with intermediate [$^{18}F$]FDG uptake where TTC staining was normal. $^{99m}Tc$-glucarate uptake was round only in TTC non-stained region. In the TTC stained regions, there were no uptake of $^{99m}Tc$-glucarate. We could not find clear relation between $^{99m}Tc$-glucarate uptake with [$^{18}F$]FDG uptake. This was partly because percent uptake of $^{99m}Tc$-glucarate was so small (less than 1 percent of injected dose) and because there were quite heterogeneity of patterns of [$^{18}F$]FDG uptake and TTC. With these findings, we could conclude that $^{99m}Tc$-glucarate were taken up only in part of ischemic tissues which were proven to be nonviable. The establishment of MCA-occluded rat model with or without reperfusion and triple imaging for $^{99m}Tc,\;^{18}F$ and TTC helped the characterization of $^{99m}Tc$-glucarate uptakes. Further work is needed to clarify the meaning or diversities or [$^{18}F$]FDG and TTC and their relation with $^{99m}Tc$-glucarate.

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A Study on the Locations of Jagiso and Dogiso in Najumok Recorded in the 'Sejongsylrok Jiliji' (『세종실록(世宗實錄)』 「지리지(地理志)」 나주목(羅州牧)의 자기소(磁器所)·도기소(陶器所) 위치 연구)

  • Sung, Yun-gil
    • Korean Journal of Heritage: History & Science
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    • v.52 no.3
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    • pp.4-37
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    • 2019
  • Buncheong Ware, which was produced for approximately 200 years from the end of the Goryeo Dynasty to the beginning of the Joseon Dynasty, was used for royal house and state affairs during the early Joseon Dynasty. Records of Buncheong Ware can be found with Jagiso and Dogiso, considered the place of production, in the 'Sejongsylrok jiliji'. This is notable, unlike celadon and white porcelain. However, compared to Gyeongsangnam-do and Gyeongsangbuk-do, the study of Jagiso and Dogiso in Jeollanam-do and Jeollabuk-do has been unsatisfactory. In this paper, we examined the locations of Jagiso and Dogiso in the Jeollanam-do prefecture. This study is focused on Najumok, located in the western part of Jeollanam-do. The following research results were obtained: First, the locations of Jagiso and Dogiso in nine areas were examined. These nine areas comprised Najumok and its immediate provinces of Haejingun, Yeongamgun, Yeonggwanggun, Hampyeonghyeon, Muanhyeon, Gochanghyeon, Heungdeokhyeon and Jangseonghyeon. Previous research results exist for some of the regions; however, only Buncheong Ware was used to estimate Jagiso and Dogiso. In this paper, we tried to discover a more accurate position of Jagiso and Dogiso through a comparison of the place names recorded in the 'Sejongsylrok jiliji' and the place names recorded in the 'Hoguchoungsu'. Also, pottery-related area names and Buncheong Ware obtained from the field survey were reviewed. Table 2 shows the specific positions of Jagiso and Dogiso in the areas examined. Second, it would appear that pottery was produced not only in Jagiso but also in Dogiso. This is because much of Buncheong Ware was unearthed in Najumok, Yeongamgun, and Muanhyeon Dogiso. However, it was only excavated from the Buncheong Kiln Site in Yucheon Village, Sangweol-ri, Yeongam-gun; there could be limitations regarding to the rest of the areas because only a field survey was conducted, not an excavation. A recent excavation at Donggok Village in Cheongdo-ri, Gimje also confirmed a Buncheong Kiln Site. There were two Buncheong Ware ('公', '上') artifacts excavated from the site, believed to be Gongnapjagi. In addition, Cheongdo-ri, where the Buncheong Kiln Site is located, was found to be an area in Wurimgokmyeon, a former Wurimgok at a Dogiso in Jeonjubu. Consequently, it would seem that Dogiso also produced porcelain (Buncheong Ware). If more data can be obtained from the excavations at sites considered to be Dogiso, the results of Dogiso-related research will be strengthened. Third, in previous surveys, field surveys and excavation surveys were based on estimates using artifacts, but the name of the location of the Jagiso and Dogiso may be confirmed more accurately by tracking the changes in the names of the administrative areas. Therefore, although it is important to conduct research using the results of surveys or excavations, changes in the place names or places related to porcelain must not be overlooked.

Investigations of Soil Chemical Properties in the Cultivation Fields of Rubus coreanus with Different Growth Ages (복분자 재배 기간에 따른 토양의 화학적 특성 변화)

  • Lee, Jin-Ho;Lee, Chang-Ho;Kang, Byeong-Suk;Ahn, Byung-Koo
    • Korean Journal of Soil Science and Fertilizer
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    • v.43 no.6
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    • pp.923-929
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    • 2010
  • This study was conducted to investigate the relations between soil chemical properties and Korean raspberry (Rubus coreanus Miq.) growth. Soils were collected from 54 sampling sites in 1 to 6 years old Korean raspberry cultivation fields (RCFs) at Gochang-gun, Jeollabuk-Do, Korea. In RCF with two to six years old plants, soil pH and exchangeable $Ca^{2+}$ and $Mg^{2+}$ contents were higher at the leaf-emergence time, but EC, available phosphorus content, CEC, and total nitrogen content were higher at the harvesting time; especially at the harvesting time, the content of available phosphorus in the RCF with 3~6 years old plants were at least three times higher than in the RCF with 2 years old plants. Water-soluble anions ($Cl^-$, ${NO_3}^-$, ${PO_4}^{2-}$, and ${SO_4}^{2-}$) in the RCF were also measured. The contents of ${NO_3}^-$ and ${SO_4}^{2-}$ were always higher in the RCF with older plants than in the RCF with younger plants, which were not affected by sampling time and sampling locations (rhizosphere and non-rhizosphere sites). However, soils collected from non-rhizosphere at the leaf-emergence time contained higher ${PO_4}^{2-}$ content, but $Cl^-$ content was higher in the soils collected from rhizosphere at the harvesting time. In general, soils in the RCFs contained excess amounts of inorganic nutrients such as available phosphorus and exchangeable $K^+$. Thus, optimal levels of soil properties for Korean raspberry cultivation should be reconsidered.

Absolute Renal $^{99m}Tc-DMSA$ Uptake and Renal Scan in Children with Vesicoureteral Reflux (방광요관역류를 가진 소아의 DMSA 스캔과 절대 신섭취율의 평가)

  • Bae, Sang-Kyun;Lee, Dong-Soo;Yang, Hyung-In;Choi, Chang-Woon;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon;Choi, Yong;Kim, Gwang-Myung;Choi, Hwang;Yeon, Kyung-Mo
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.2
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    • pp.327-332
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    • 1992
  • $^{99m}Tc-dimercaptosuccinic$ acid (DMSA) 주사후 일정시간에 측정한 절대적 신섭취량은 기능이 살아있는 신피질량과 관계있다. 소아의 신기능은 출생후 계속 성숙되어 생후 약 $1\sim2$년에 성인의 기능에 도달하는데 DMSA섭취도 성인과는 다른 양상을 보일 것으로 기대되며 신질환에서 절대적 신섭취율의 평가는 연령을 고려해야 할 것이다. 저자들은 DMSA 스캔을 시행한 소아 환자를 대상으로 스캔상 피질 결손이 없으며 양측신의 섭취율이 비슷하고 혈중 크레아티닌치가 정상인 경우를 대조군으로 하여 연령별 DMSA의 절대적 신섭취율을 구하였고 방광요관역류를 가진 환아를 대상으로 DMSA스캔을 시행하고 신섭취율을 조사하였다. 1) 대조군은 모두 65명으로 좌우측 신섭취율의 유의한 차이는 없었으며 연령에 따라 2세경에 플라토에 도달하였는데 한쪽 신장의 평균섭취율은 3개월 미만이 $14.5{\pm}3.1%$ ID, 3개월에서 6개월 미만이 $17.2{\pm}2.1%$ID, 6개월에서 1년 미만이 $18.4{\pm}1.3%$ID, 1년에서 1년6개월 미만이 $19.3{\pm}1.1%$ID, 1년 6개월에서 2년 미만이 $21.9{\pm}2.0%$ID, 2세이상 15세이하가 $20.1{\pm}0.6%$ID였으며 전체 평균섭취율은 $19.4{\pm}0.5%$ID (injected dose, $mean{\pm}S.E.$)였다. 2) 방광요관역류를 가진 환아는 55명 (일측성 56명, 양측성 29명)으로 109신장을 대상으로 하였다. 방광요관역류의 정도와 피질결손의 수와는 대체로 비례관계가 있었으나 방광요관역류가 없으면서 피질결손이 있는 경우가 25신장중 2예 (8%)였으며, 방광요관역류가 있는 84신장중 27예 (32.1%), 이중에서 방광요관역류가 3도 이상인 62신장중 13예 (21%)에서는 피질결손이 없었다. 3) 이환신의 DMSA 섭취율을 연령에 따른 대조군의 섭취율에 대한 비(섭취율비)로 나타내면 한쪽에 역류가 있을 때 이환신의 경우 $0.55{\pm}0.06$, 정상신의 경우 $1.34{\pm}0.05$이었으며, 양쪽에 역류가 있을 때는 평균 $0.82{\pm}0.08$ $(mean{\pm}S.E.)$ 이었다. 4) 피질결손이 있는 신장의 절대 DMSA 신섭취율은 감소되어 있었고 상대측 신장의 섭취율은 피질 결손이 있더라도 대상적인 증가의 경향을 보였다. 이상의 결과로 소아에서 DMSA 절대적 신섭취율의 연령에 따른 변화를 알 수 있었으며 방광요관역류의 정도와 피질결손의 정도가 반드시 비례하지만은 않아서 시간경과에 따른 추후 검사가 필요하리라 생각된다. 또한 방광요관역류가 있는 환아에서 DMSA 섭취율로 신기능을 평가할 때, 특히 영유아에서 연령에 따른 고려가 있어야 할 것으로 보인다.

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Physical Dosimetry in Radioactive Iodine Treatment in the Patients with Thyroid Cancer (갑상선암 환자에 대한 방사성옥소 치료시 물리적 선량 측정)

  • Kim, Myung-Seon;Jeong, Nae-In;Lee, Jai-Yong;Kim, Chong-Soon;Kim, Chong-Ho;Lee, Myung-Chul;Koh, Channg-Soon;Kim, Hee-Geun;Kang, Duck-Won;Song, Myung-Jae
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.1
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    • pp.124-132
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    • 1994
  • Radioactive iodine has been widely used in patients with thyroid cancer combined with surgical treatment. However, due to individual variations in absorption and excretion and uptake by tumor tissue of radioactive iodine, there are differences in therapeutic effect and adverse effects even if the same doses are administrated. So this study compared the therapeutic effect and radiation hazard by measuring internal radiation dose. Of total 27 patients with well differentiated thyroid cancer who had been thyroidectomized, we administered radioactive iodine 100 mCi, 150 mCi, 200 mCi. According to BEL DOSIMETRY PROTO-COL, beta and gamma ray dose were estimated from a pelt of the logarithm of the percent of dose per liter of whole blood versus day, and percent dose retained versus day using somilogarithmic paper, respectively. 1) Physical dose to whole blood averaged $56.54{\pm}13.02$ rad in 100 mCi administered group, $76.83{\pm}19.97$ rad in 150 mCi administered group, $95.08{\pm}25.51$ rad in 200 mCi administered group and there has been a significant correlation among the groups. 2) Mean percent dose retained 48 hours later was 26.34%. 3) There was no significant correlation of physical dose between absence and presence of metastasis. 4) 17 of 19 patients who has been followed up with TSH and serum throglobulin, Thallium scan were successfully ablated by radioactive iodine. 5) Leukocyte, lymphocyte, neutrophil, platelet counts all deelined in 4.6 weeks and most of all were restored 3 months later. 6) There was no significant correlation between physical dosimetry and biologic dosimetry. Generally administered doses of radioactive iodine (100-200 mCi) to patients with thyroid cancer postoperatively had developed transient bone marrow suppression and minimal chromosomal aberration, but they were within safety dose to blood (200 rad). And there has been no significant differences in residual dose 48 hours later between Korean and western people.

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Ablation of Remnant Thyroid Tissue with I-131 in Well Differentiated Thyroid Cancer After Surgery (분화성 갑상선암에서 수술 후 I-131을 이용한 잔여 갑상선 조직의 제거 성적)

  • Kim, Yu-Kyeong;Lee, Dong-Soo;Cho, Bo-Yeon;Jeong, Jae-Min;Lee, Myung-Chul;Koh, Chang-Soon;Chung, June-Key
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.3
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    • pp.339-345
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    • 1997
  • To evaluate the effectiveness of I-131 in ablation of residual thyroid tissue, we analyzed 350 patients with thyroid cancer who were treated with various doses of I-131 after surgery for thyroid cancer Two hundred fifty five patients were treated with 1.1GBq(30mCi) of I-131 for ablation of remnant thyroid and one hundred seventeen patients received more than 2.8GBq(75mCi) of I-131. We determined the effectiveness of ablation by following I-131 whole body scan. Absent visible uptake or minimal uptake in thyroid tissue were considered as successful ablation. Of 255 patients who received doses of 30mCi I-131 therapy, 131 patients(51%) showed successful ablation of residual thyroid tissue with $2.6{\pm}1.7$ times of I-131 therapy. Of 117 patients who received doses of the more than 75mCi I-131, 84 patients(72%) had successful remnant thyroid ablation with $1.6{\pm}1.1$ times of I-131 therapy, According to the extent of surgery, successful ablation rates were 78%, 62%, 54%, 33% in patients who underwent total thyroidectomy, subtotal thyroidectomy, lobectomy and isthmectomy, lobectomy or tumorectomy, respectively. This study showed that ablation of remnant thyroid after surgery with 30mCi I-131 was successful only in 50%. Therefore, in cases of patients with high risk for recurrence, we recommend high dose I-131 for ablation of remnant after total thyroidectomy.

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Suitability Class Criteria for Red Pepper with Respect to Soil Morphology and Physical Properties (토양의 형태 및 물리적 특성을 고려한 고추재배 적지 기준 설정)

  • Jung, Sug-Jae;Park, Byeong-Sik;Jang, Gab-Sue;Hyun, Byung-Keun;Rim, Sang-Kyu
    • Korean Journal of Soil Science and Fertilizer
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    • v.37 no.5
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    • pp.336-340
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    • 2004
  • The objective of this study was to establish the decision criteria of land suitability for red pepper using soil morphological and physical properties. The investigation was carried out in Jechen, Goesan, Euiseong, Andong, Gochang and Pyongchang district in Korea. The obtained results showed that factors related to the decision criteria of the land suitability for red pepper cultivation were soil texture, soil drainage class, land slope, available soil depth and stone content. The criteria of the best suitable soil for red pepper was coarse loamy, well drainage class, C-slope (7-15%), 10-20% gravel content and available soil depth deeper than 100 cm. Also in the best suitable soil, hardpan was located below 100 cm from the soil surface. Outbreak rate of phytophthora blight occurred well in the soils with high clay content, poor drainage class, low land slope and low gravel content. Database determining the decision criteria of the land suitability for red pepper in Jinchen-gun was established by Arc info GIS tool.

Cross-sectional and Comparative Study between First Attack and Reattack Groups in Acute Stroke Patients - Multi-Center Trials (급성기 중풍환자의 재발군과 초발군에 대한 단면조사연구 - 다기관 임상연구)

  • Lee, In-Whan;Gwak, Ja-Young;Cho, Seung-Yeon;Shin, Ae-Sook;Kim, Na-Hee;Kim, Hye-Mi;Na, Byung-Jo;Park, Seong-Uk;Jung, Woo-Sang;Moon, Sang-Kwan;Park, Jung-Mi;Ko, Chang-Nam;Cho, Ki-Ho;Kim, Young-Suk;Bae, Hyung-Sup
    • The Journal of Internal Korean Medicine
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    • v.30 no.4
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    • pp.696-707
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    • 2009
  • Objective : We designed this study to investigate differences between stroke reattack and stroke first attack group to establish fundamental data and prevent a secondary stroke. Methods : 826 subjects were recruited from the patients admitted to the department of internal medicine at Kyung Hee University Oriental Medical Center, Kyung Hee University East-West Neo Medical Center, Kyungwon University Incheon Oriental Medical Center, Kyungwon University Songpa Oriental Medical Center and Dongguk University Ilsan Oriental Medical Center from 1 April 2007 to 31 August 2009. We compared general characteristics, classification of diagnosis, subtypes of cerebral infarction, risk factors, Sasang constitution, diagnostic classifications between stroke reattck and stroke first attack groups. Results : 1. In general characteristics, age differed significantly between the reattck and first attack groups. 2. Classification of diagnosis differed significantly between reattck and first attack groups. 3. In risk factors, hypertension, diabetes mellitus, alcohol drinking, and stress were significantly different between reattck and first attack groups. 4. Diagnostic classifications were significantly different between reattck and first attack groups. Conclusion : To prevent recurrence of stroke, education on stroke risk factors associated with recurrence is needed. In addition, those who are diagnosed as Dampness-Phlegm need to be well-controlled.

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Trematodes larva in 3 species of bivalves )Corbicula japonica, Sinonovaculla constrica and Ruditaps philippnarum) (간석지산 이매패에서의 흡충류 유충에 관한 연구)

  • Kim, Yeong-Gil;Yun, Gwon-Sik
    • Journal of fish pathology
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    • v.16 no.3
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    • pp.203-213
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    • 2003
  • The present study was conducted to research some parastic trematodes species in marine bivalves which are widely distributed in the western sea in Korea. From April, 2001 to October, 2002, marsh calm (Corbicula japonica) were obtained from Kochang bay near the Sunun temple and razor calm (Sinonovaculla constricta) from Kaehwado. Short necked calm (Ruditapes philippnarum) were sampled from Ochungdo, Mardo and Kaeyado. Cercaria corbiculae was found in the gonad of C. japonica with a low infection rate of 0.83%. The cercaria and the sporocyst were sized $278{\times}98{\mu}$ and $890{\times}275{\mu}$, respectively. Some encysted larvae of Parvatrema duboisi sized $0.351{\times}0.182mm$ were firstly found in the mantle of S. constricta in Korea. Each S. constricta contained 1-9 cysts and the infection rate was 48.3%. Cercaria tapidis was found in the both gonad and mantle of R. philippinarum. The annual average infection rate in the R. philippinarum from Ochungdo was 7.7%. This rate was much higher than those from Solri near the Kum river estuary in 1981. The infection rate of C. tapidis in R. philippinarum was different in sizes. The maximum rate was 4.8% in size 3.6-4.0cm and the minimum rate 0.8% in size 4-5cm.

Methodology for Designing Inter-device Connectivity by Classifying User Experience Step (사용자 경험단계의 분류를 통한 기기간 연결성디자인 방법론)

  • Hong, Sung-Soo;Yoo, Soung-Min;Ahn, Hyo-In;Ko, Chang-Suk
    • 한국HCI학회:학술대회논문집
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    • 2008.02b
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    • pp.456-459
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    • 2008
  • We are now in the era of digital convergence with CE products and PC at the center, but product diversification occurs in the same breath. Each device may perform its own functions itself independently, but proportion of the inter-device usage is increasing gradually by concept of a home network and ubiquitous widely prevailed. The consumer's need of inter-device connection will take the dominative position of the market. Therefore, we can easily forecast that diversification of the products may inevitably lead connectivity patterns complicated considering recent market situation and trends. In this paper, we propose the methodology for designing inter-device connectivity which covers issues such like segmenting numerous number of connectivity pattern, and establishing their structure of control. Our methodology also supports the inter-device connection with extensive latitudes and a multi-device simultaneous control. In order to present inter-device connectivity guideline, we define four stages of a user experience - Connection, Configuration, Use, Disconnection. Based on the 4 user experience stages, we suggest a specific connectivity designing guideline for each step.

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