• Title/Summary/Keyword: 고지혈증

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고지혈증의 원인과 치료 - 당뇨병환자에게 처방되는 고지혈증약

  • Jo, Jeong-Gu
    • The Monthly Diabetes
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    • s.285
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    • pp.23-29
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    • 2013
  • 당뇨병은 심근 경색의 재발 위험이나 심혈관 질환에 의한 사망 위험이 높다는 것은 잘 알려진 사실로 당뇨병 자체로도 관상동맥질환이 있는 것과 같이 대등한 위험인자로 취급하도록 권고되고 있다. 이러한 당뇨병에 이상지질혈증, 고혈압, 복부비만이 동반되어 있는 경우를 대사증후군으로 명명하기도 하며 심혈관질환 위험이 훨씬 증가한다.

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The Effects of Pulsed Electromagnetic Fields on Blood components, Antioxidant enzymes and Reactive Oxygen in Hyperlipidemic Rats (맥동전자장이 고지혈증 흰쥐의 혈액 성분, 항산화 효소 및 활성 산소에 미치는 영향)

  • Bang, Hyun-Soo;Jeong, In-Ho;Lee, Sang-Deok
    • Journal of Digital Convergence
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    • v.12 no.7
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    • pp.349-356
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    • 2014
  • The present study was aimed to investigate the effects of the application of pulsed electromagnetic fields on the blood components associated hyperlipidemia, antioxidant enzymes and reactive oxygen. The subjects were divided into three groups: General Diet, High fat Diet, High fat diet and pulsed electromagnetic fields. Pulsed electromagnetic field was applied with pulsed electromagnetic energy therapy equipment. The Glucose, free fatty acids, triglycerides, cholesterol and insulin was used to measure hyperlipidemia-related blood components, and the GSH, GRD, XO and MDA was used to measure antioxidant enzymes and reactive oxygen. The applied pulsed electromagnetic field has improved the concentrations of blood components and increasing GSH and GRD, that were decreased due to a high-fat diet and by reducing the increased MDA and XO to a level of general diet group. Therefore, the applied pulsed electromagnetic field can be the effective treatment for changes in the blood composition of hyperlipidemic rats, enhancement of antioxidative activity and the inhibition of reactive oxygen.

Effect of Methanolic Extract of Pachymeniopsis elliptica on Lipids Component of Hyperlipidemic Rats (해조류 참도박의 메탄올 추출물이 고지방식이 흰쥐의 지질성분에 미치는 영향)

  • 박종철;장영인;도명술;김석환;최종원
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.6
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    • pp.958-962
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    • 1996
  • Hypolipidemic effect of methanolic extract of marine algae, Pachymeniopsis elliptica was examined in hyperlipidemic rats. Male $Sprague-Dawley(120\pm5g)$ rats were divided into five groups and fed high fat diets for four weeks. Each group was orally administered with methanolic extract of P. elliptica (PEM, 250, 500mg/kg), benzofibrate(BZF, 30mg/kg) and cholestyramine resin(CSR, 100mg/kg) daily for one week. Significant decreases in cholesterol, total lipid and triglyceride of both blood and liver were observed by the administration of the extract. But the levels of LDL- and HDL-cholesterol and the activity of lipase were not changed. Such results suggest that the extract may promote the fecal excretion of bile acid in hyperlipidemic rats.

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Biodegradation of Blood Lipid Lower Agents (BLLAs) in Biological Activated Carbon (BAC) Process (BAC 공정에서의 고지혈증 치료제 생물분해 특성)

  • Yoom, Hoon-Sik;Son, Hee-Jong;Ryu, Dong-Choon;Yoo, Pyung-Jong
    • Journal of Korean Society of Environmental Engineers
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    • v.39 no.3
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    • pp.124-131
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    • 2017
  • In this study, We investigated the effects of water temperature and empty bed contact time (EBCT) on the biodegradability of 8 blood lipid lower agents (BLLAs) in biological activated carbon (BAC) process. Experiments were conducted at three water temperatures ($8^{\circ}C$, $16^{\circ}C$ and $24^{\circ}C$) and three EBCTs (5 min, 10 min and 15 min). Increasing water temperature and EBCT increased the biodegradation efficiency of BLLAs in BAC process. Simvastatin and fenofibrate were the highest biodegradation efficiency, but atorvastatin and clofibric acid were the lowest. The kinetic analysis suggested a pseudo-first-order reaction model for biodegradation of 8 BLLAs at various water temperatures and EBCTs. The pseudo-first-order biodegradation rate constants ($k_{bio}$) of clofibric acid and atorvastatin were $0.0075min^{-1}$ and $0.0122min^{-1}$ at $8^{\circ}C$, and were $0.0540min^{-1}$ and $0.0866min^{-1}$ at $24^{\circ}C$, respectively. By increasing the water temperature from $8^{\circ}C$ to $24^{\circ}C$, the biodegradation rate constants ($k_{bio}$) were increased 7.1~7.2 times.

모야모야병을 동반한 당원병 Ia형 1례

  • Kim, Yeong-Seon;Lee, Dong-Hwan
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.4 no.1
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    • pp.1-4
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    • 2004
  • 저자들은 4년 전 모야모야병으로 진단되어 수술 받았던 16세의 여아에서 지속적으로 고지질혈증이 있어 검사를 시행한 결과 가족 중 여동생에게서도 고지질혈증이 있음이 확인되었고 대사성산증, 고요산혈증, 젖산혈증 및 간비대가 지속되어 시행했던 염기 서열 분석에서 당원병 type Ia로 진단된 1례를 경험하였기에 보고하는 바이다.

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The Factors Associated with Serum Lipid Levels in the Elderly from Middle Income Status. (도시중류노인들의 혈청 지질지표와 이와 관련 있는 요인들에 관한 연구)

  • 손숙미;이현정
    • Proceedings of the KSCN Conference
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    • 2003.05a
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    • pp.146-146
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    • 2003
  • 우리나라노인들의 수명은 식생활, 의료, 위생 및 주거환경의 향상으로 계속 증가되고 있다. 수명의 증가는 노인의 건강에는 오히려 위험요인으로 작용하여 현실적으로 60세 이상 노인들의 2명중 1명이 질병에 걸린 것으로 나타났으며 많은 수의 노인들이 고혈압, 고지혈증, 당뇨, 관절염에 시달리고 있다. 그 중에서도 고지혈증은 심혈관질환, 특히 관상동맥질환의 중요한 인자이며 동시에 뇌혈관질환의 중요한 인자이다. (중략)

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당뇨병과 비만

  • 김성래
    • The Monthly Diabetes
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    • s.148
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    • pp.16-17
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    • 2002
  • 비만과 관련된 질환은 당뇨병, 고혈압, 고지혈증, 죽상경화증(동맥경화증), 심근경색증, 지방간, 담석증, 골 관절염, 통풍, 폐쇄성 수면 무호흡증, 대장암, 직장암, 전립선암, 유방암, 자궁내막암 등의 각종 암, 불안, 우울, 적응장애, 히스테리 등의 심리적 질환 등이 있다. 비만이 있을 때 우리 몸에서는 인슐린 자체에 대한 저항성이 생겨서 말초조직에서의 포도당 이용이 감소된다. 연구에 의하면 표준체중의 45$\%$ 이상을 초과한 비만환자는 당뇨병 발생의 위험도가 30배 증가된다고 알려져 있다. 비만이 있을 때 흔히 동반되는 질환들 중 특히 고혈압, 고지혈증, 죽상경화증 등의 질환은 당뇨가 있을 때 흔히 동반될 수 있는 질환들이고, 인슐린 저항성과 깊은 관계가 있는 질환들로 당뇨인들에게 비만은 매우 중요한 질환이라고 할 수 있겠다.

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A Web-based Internet Program for Nutritional Assessment and Diet Management of Patient Having Hyperlipidemia (고지혈증 환자의 웹기반 식사관리 및 영양평가 프로그램)

  • 한지숙;허지연
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.2
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    • pp.287-294
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    • 2003
  • The purpose of this study was to develop a web-based internet program for nutritional assessment and diet management of patient having hyperlipidemia. Hyperlipidermia were classified by hypercholesterolemia and hypertriglyceridemia. The program consisted of four parts according to their functions and contents. The first part explained the metabolism of lipids and defined the hyperchotesterolemia and hypertriglyceridemia. The second part is to assess the general health status such as body weight, obesity index, basal metabolic rate and total energy requirement by the input of age, sex, height, weight and degree of activity. This part also provides the Patient with menus lists and 1 day menu suitable to his weight, activity and the status of hyperlipidemia and offers the information for food selection, snacks, convenience foods, dine-out, behavioral modification, cooking methods, food exchange lists, and information on energy and nutrients of foods and drinks, and top 20 foods classified by nutrients. The third part is designed to investigate diet history of patient, that is, to find out his inappropriate dietary habit and give him some suggestions for appropriate dietary behavior. This part also offers on-line counseling and frequently asked Questions. The fourth part is evaluating their energy and nutrients intake by comparing with recommended dietary allowance for Koreans or standardized data for patient with hyperlipidemia. In this part, it is also analyzing energy and nutrients of food consumed by food group and meals, and evaluating the status of nutrient intake. These results are finally displayed as tabular forms and graphical forms on the computer screen.