• The Monthly Diabetes
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• s.188
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• pp.11-13
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• 2005

인슐린 저항성 증후군 환자나 당뇨병 발병 고위험군, 당뇨병 초기 환자에서는 인슐린 저항성 및 고인슐린혈증은 일반적으로 함께 나타나는 상황이다. 그러나 당뇨병이 이미 발병하여 매우 높은 혈당 상태에 있거나 당뇨병이 오래 진행되어 인슐린 분비능력이 매우 하강한 환자에서는 인슐린저항성이 심한데도 불구하고 고인슐린혈증은 나타나지 않을 수 있다.

• Journal of Chest Surgery
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• v.32 no.5
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• pp.480-483
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• 1999

The widely accepted method for coronary artery bypass grafting(CABG) is performing the distal coronary artery anastomoses on the flaccid and nonbeating heart with the aid of cardiopulmonary bypass(CPB) and cardioplegic arrest. However, current cardioplegic techniques are not consistent in avoiding myocardial ischemic damages especially in high risk patients undergoing CABG. In this regard, "Off-Pump" seems to be an ideal method for preventing myocardial ischemic damage and adverse effects during CPB. However, "Off-pump" CABG is not always technically feasible. We report 2 cases of "On-pump" CABG performed on the beating heart in high risk patients; The first patient had left ventricular dysfunction(Ejection Fraction=25%), and the second patient had cardiogenic shock after percutaneous transluminal coronary angioplasty.

• Proceedings of the Korea Information Processing Society Conference
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• 2014.11a
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• pp.492-494
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• 2014

정보유출사고가 증가됨에 따라, 기업 및 기관 내 주요정보(개인정보 및 핵심기술)가 유출되어 큰 피해가 발생하고 있다. 이러한 정보유출 사고 중 대부분이 내부자에 의한 고의 또는 실수로 발생하는 경우가 대부분이다. 이를 방지하기 위해 다양한 보안 솔루션을 도입하여 운영하고 있지만 내부자에 의한 정보유출사고는 본인이 소유하고 있는 권한을 이용하여 불법적인 정보유출을 시도하는 것으로, 이러한 위험행동을 탐지하는 것은 쉽지 않다. 이를 해결하기 위해 기업 및 기관에서는 기 구축된 다양한 보안 솔루션을 통합하여 모니터링 할 수 있는 '내부정보유출방지 모니터링시스템'을 구축하고 있으며, 내부정보유출방지 모니터링을 위한 연구도 지속적으로 진행되고 있다. 따라서 본 논문에서는 중점관리 대상(고위험군) 선정을 통해 효율적인 내부정보유출방지 모니터링을 수행할 수 있도록 연구하고자 한다.

• Journal of the Korea Convergence Society
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• v.9 no.1
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• pp.241-251
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• 2018

The study is a preliminary study of the effectiveness of the structured cognitive behavioral arbitration program targeting elementary school students who perform high risk problems based on schools for convergence with local communities. The program is designed to be practiced by semi-trained professionals. To screen high-risk students, total 102 students were tested K-CBCL and those who scored over 60T on problem behavior syndrome scale were recruited. 32 students were selected and devided into intervention group and control group. Intervention group was received 90-minutes-sessions per week, for nine weeks. The program was done by graduate students and undergraduate students majoring counseling and supervised by school psychologist. The internalization group showed significantly lower score in Internalization, anxiety/depression, and externalization group showed externalization, aggressive behavior. but mixed group didn't showed significantly lower score. Implications of the results, limitations and suggestions for future study were mentioned.

• Journal of dental hygiene science
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• v.11 no.3
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• pp.229-234
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• 2011

This study obtained DMFT index(9271 people) in population with more than 6 years old based on data of 2009 Korea National Health and Nutrition Examination Survey, and calculated SiC index(2,517 people) by classifying group with high risk, which is 1/3 in high rank out of it. The aim was to confirm existence of the group with high risk of dental caries, and was to emphasize necessity of preventive strategy for the group with high risk. Statistical analysis was carried out t-test by using STATA 11.0 program. 1. DMFT index accounted for 45.0%(4,174 people) for men and 55.0%(5,097 people) for women. SiC index stood at 2,517 people. Men accounted for 36.3%(914 people). Thus, women were larger with 64.7%(1,603 people). 2. Seeing the mean in DMFT index and SiC index, the more rise in age led to the bigger difference in the mean between two groups. Especially, the difference was shown more than 4 points on the average for 13 and 14 years old and more than double on the average from over 15 years. 3. As a result of comparing gender, DMFT index was higher in women than men from over 14 years old. SiC index wasn't significant. However, women were indicated to be 1 piece more than men at the age of 9 and 14. 4. As a result of comparing by region, both DMFT index and SiC index were indicated to be higher in the rural area for their over 60s. Seeing the above results, the group with high risk is showing the higher rate of experiencing dental caries than DMFT-index in the whole. Thus, the comprehensively & intensively preventive management seems to be likely needed on group with high risk.

• Korean Journal of Clinical Laboratory Science
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• v.49 no.4
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• pp.446-454
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• 2017

Human papillomaviruses (HPVs) are major causes of cervical cancer. Sixteen high risk HPVs, including HPV 16, HPV 18, HPV31, HPV 33, HPV 35, HPV 39, HPV 45, HPV 51, HPV 52, HPV 53, HPV 56, HPV 58, HPV 59, HPV 66, HPV 68, and HPV 69 are found in cervical cancer. HPVs 16 and 18 are mainly presented in 70% of cervical cancer. Therefore, identifying the presence of these high-risk HPVs is crucial. The objective of this study is to establish the HPV ViroCheck for detecting 16 HR-HPVs and genotypes of HPVs 16 and 18, as well as to analyze the analytical performance of HPV ViroCheck. We performed the analytical sensitivity of HPV E6 / E7 genes of 16 high risk HPVs to confirm the limit of detection. Then, a cross reactivity of HPV ViroCheck with microorganisms and viruses related to the cervix were analyzed for analytical specificity. Analytical sensitivity of high risk HPV genotypes ranged from 1 to 100 copies when using cloned DNAs. The limit of detection was 10 cells for both SiHa and HeLa cells. Cervical-related microorganisms and viruses did not show cross-reactivity to HPV DNA. Moreover, the intra- and inter-assay coefficient variations (CVs) were below 5%. In conclusion, HPV Virocheck will be useful for the detection of 16 HR HPVs, as well as HPV 16 and HPV 18 genotypes rapidly.

• Journal of Chest Surgery
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• v.34 no.12
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• pp.895-900
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• 2001

Background : This study aimed to evaluate the usefulness of preoperative placement of intraaortic balloon pump(IABP) in reducing operative risk and facilitating posterior vessel OPCAB in high risk patients with left main disease( 75％ stenosis), intractable resting angina, postinfarction angina, or left ventricular dysfunction(ejection fraction 35％). Material and Method : One hundred eighty- nine consecutive patients who underwent multi-vessel OPCAB including posterior vessel revascularization were studied. The patients were divided into group I(n=74) that received preoperative or intraoperative IABP and group II(n=115) that did not receive IABP. In group I, there were 39 patients with left main disease, 40 patients with intractable resting angina, 14 patients with left ventricular dysfunction and 7 patients with postinfarction angina. Ten patients received intraoperative IABP support due to hemodynamic instability during OPCAB. Result : There was one operative mortality in group I and two mortalities in group II. The average number of distal anastomoses was not different between group I and group II(3.5$\pm$0.9 vs 3.4$\pm$0.9, p=ns). There were no significant differences in the number of posterior vessel anastomosis per patient between the two groups. There were no differences in ventilator support time, length of hospital stay, and morbidity between the two groups. There was one case of IABP-related complication in group I. Conclusion : IABP facilitates posterior vessel OPCAB in high risk patients, with comparable surgical results to low risk patients

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.314-320
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• 2021

With the increasing age of motherhood in recent years, attributed to late marriages due to social or environmental factors, the Down's syndrome screening test using biochemical markers has become essential for pregnant women. The process of diagnosing Down's syndrome pregnancy in the high-risk group subjects involves chromosomal analysis, which is performed on samples obtained through invasive procedures such as chorionic biopsy or amniotic fluid. Thus, to reduce unnecessary invasive tests and lower the risk to mother and fetus, it is important to identify a screening test with low risk and high Down's syndrome detection rate. Recently, as the average age of mothers has increased, numerous inspection agencies have classified high-risk mothers as women over the age of 35 years. This study evaluated a total of 36,436 pregnant women aged between 17 to 46 years, and who requested prenatal screening at an inspection agency in Yongin in 2018. Test (13,690 people) Four tests were conducted by applying the time-resolved fluoroimmunoassay method using the direct sandwich and indirect sandwich technology, and the immunoassay method using the sandwich method. We aimed to confirm the difference in positivity rate with increasing age of the subjects. We believe that in future, data obtained from this study will be very useful for the prevention and treatment of Down's syndrome risk at varied inspection institutions, and for prospective mothers.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.389-397
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• 2018

The purpose of this study is to evaluate the prevalence and related risk factors of problem drinking in the Korean adult population. Participants (n=7,867) aged 19 years or older were selected from the Korea National Health and Nutrition Examination Survey [KNHANES] of 2007-2008. Sociodemographic characteristics and AUDIT score were obtained from the KNHANES dataset. AUDIT scores were categorized into three groups, including low risk, intermediate risk, and high-risk alcohol drinking according to WHO guidelines. In this study, the prevalence of high-risk and intermediate-risk alcohol drinking were 12.2% and 21.0%, respectively. Adjusted mean AUDIT score was higher in men, younger individuals, as well as those with lower education levels and those that smoked. Results revealed that demographic variables, including sex, age, education level, and smoking, were important factors affected high-risk drinking. In particular, since smoking was the most significant risk factor, the adjusted odds ratio for high-risk drinking among participants that smoked was 4.78 [(95% confidence interval (CI)=3.75-6.10, p<.0001)]. This study suggests that men, younger age, low educational level, and smoking are the risk factors for a high-risk alcohol drinking.

• The Journal of the Convergence on Culture Technology
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• v.3 no.2
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• pp.15-20
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• 2017

We are investigated about the Hepatitis infection risk of the funeral director related to wearing PPE(Personal Protect Equipment) within Metropolitan, Chungcheong and Gyeongsang regions in Korea. We are classified that the vaccinated group was classified as low risk group and the non-vaccinated group was classified as high risk group. And we are analyzed the risk rate of infection based on whether or not to wear PPE(personal protective equipment) among high-risk groups. The result is as follows. The mask wearing rate of high-risk group about HAV(hepatitis A virus) is three times lower than that of low-risk group. The surgical glove wearing rate of high-risk group about HBV(hepatitis B virus) is twice lower than that of low-risk group. The surgical glove and mask not wearing rate among the high-risk group observe that potential infection risk was high 4.23 times and 3.5 times, respectively. We are concluded that increasing the risk of potential infection risks from the funeral director could result in increased risk of infection to national public health, including the bereaved family. We are suggested that the funeral director must be bound to vaccinate against hepatitis and make PPE mandatory. It is deemed necessary for the government to develop policies to promote personal health and national health care.