• Title/Summary/Keyword: 고신대학교

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후두전적출술 후 Amatsu식 기관식도누공술을 시행한 환자에 대한 음성학적 및 영상학적 분석

  • 이한국;김순곤;유태현;이봉희;이윤우;이강대
    • Proceedings of the KSLP Conference
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    • 1999.11a
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    • pp.185-185
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    • 1999
  • 진행된 후두암종 환자에서는 후두전적출술이 가장 바람직한 치료 방법이다. 후두 기능이 상실된 환자에서 음성재활은 삶의 질을 향상시키기 위해서 필요하며 음성재활법으로 기관식도누공술, 식도발성, 전기후두에 의한 발성이 대표적인 방법이다. 고신대학교 이비인후과에서 후두 편평상피세포암종으로 후두전적출술과 Amatsu식 기관식도 누공술을 시행 받은 환자들 중에 음성분석이 가능한 12명을 대상으로 조사하였다. (중략)

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Association of Cognitive Dysfunction with Thyroid Autoantibody (갑상선 자가항체와 인지기능 저하의 연관성)

  • Han, Dong Kyun;Cheon, Jin Sook;Choi, Young Sik;Kim, Ho Chan;Oh, Byoung Hoon
    • Korean Journal of Psychosomatic Medicine
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    • v.24 no.2
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    • pp.227-235
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    • 2016
  • Objectives : The aims of this study were to know the frequency of cognitive dysfunction among patients with autoimmune thyroid disorders, and to reveal influencing factors on it, especially to clarify association with autoimmune thyroid antibodies. Methods : From sixty-five female patients with autoimmune thyroid disorders, demographic data were obtained by structured interview. Their cognitive funtions were measured using the MMSE-K and the MoCA-K tests. Depression was evaluated by the K-HDRS. Results : 1) Among patients with autoimmune thyroid disorders, 7.69% of them were below 24 on the MMSE-K, while 10.77% were below 22 on the MoCA-K. The frequency of cognitive deficit was not significantly different according to having positivity to antimicrosomal antibodies or not. 2) The antimicrosomal antibody-positive patients had significantly higher antithyroglobulin antibody titers, antimicrosomal antibody titers, and TSH concentration, while had significantly lower free T4 levels(p<0.05, respectively). 3) The total scores of the MMSE-K and the MoCA-K had significant correlation with age, marital status, antithyroglobulin antibody titers and K-HDRS(p<0.05, respectively). 4) The regression analysis revealed that variables such as age, education, autoimmune thyroid antibodies, thyroid function and depression did not influence on cognitive function of patients with autoimmune thyroid disorders. Conclusions : Our results could not support that cognitive function of patients with autoimmune thyroid disorders had correlation with autoimmune thyroid antibodies.

FOLFIRI Regimen as a Second-line Chemotherapy after Failure of First-line Chemotherapy in Advanced Gastric Cancer (진행성 위암에서 1차 항암화학요법에 실패한 환자에서 2차 항암화학요법으로 FOLFIRI요법의 효용성에 대한 연구)

  • Yong Kang Lee;Jae Hyun Kim;Jun Chul Park;Hee Seok Moon;Sung Eun Kim;Jin Seok Jang;Joo Young Cho;Eun Sun Kim;Si Hyung Lee;Sang Kil Lee
    • Journal of Digestive Cancer Research
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    • v.5 no.2
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    • pp.113-119
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    • 2017
  • Background: Second line chemotherapy is often considered in advanced gastric cancers. We assessed irinotecan in combination with fluorouracil in patients experienced diseases progression after first line chemotherapy. Methods: Prospective trial was done at 7 centers in republic of Korea. Patients aged 18 years or older with advanced gastric adenocarcinoma and disease progression on or within 4 months after first-line chemotherapy were assigned to receive irinotecan 180 mg/m2 and 5-fluorouraicl 400 mg/m2 intravenously bolus injection on days 1 and leucovorin 200 mg/m2 for 2 hours and 5-fluorouracil 600 mg/m2 for 22 hours intravenously infusion on day 2 of a 14-day cycle (FOLFIRI group). The primary endpoint was objective tumor response (OR). Efficacy analysis was by per-protocol, and safety analysis included all patients who received at least one treatment with study drug. Results: Between January 1, 2014 and December 31, 2016, 28 patients were assigned to FOLFIRI treatment. Of those 20 patients were completed the study protocol. Per-protocol analysis, two patients among 20 subjects (10.0%) showed partial response. Overall survivals of FOLFIRI group; median 10.1 months [95% CI 4.9-15.3] Grade 3 and higher adverse event that occurred about 5%, but grade 3 or higher febrile neutropenia or life threatening complication was not reported. Conclusion: Combination chemotherapy with irinotecan, 5-FU, and LV is feasible in gastric cancer patients previously treated with platinum-based chemotherapy

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Structural Equation Modeling of Retention Intention in Nurses (간호사의 재직의도 구조모형)

  • Cho, Hun Ha;Kang, Jung-Mi;Lee, Kyoung-Eun
    • Journal of East-West Nursing Research
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    • v.27 no.2
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    • pp.95-103
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    • 2021
  • Purpose: This study was conducted to investigate the structural equation modeling of retention intention in nurses. Methods: A total of 210 nurses from three hospitals in B city, South Korea participated in this study. A structural equation model was constructed to verify the fitness of this model. Data were analyzed using SPSS 20.0 and AMOS 21.0 programs. Results: The hypothetical model appeared to fit the data. Three of the selected six hypotheses for the hypothetical model were statistically significant. The retention intention model showed significant direct effects for job crafting and job demands and indirect effects for relation oriented culture, which explained 28% of the variation in nurses' retention intention. Conclusion: We found that nurses' job crafting behavior and job demands had significant influences on retention intention and relation oriented culture which affected by the factors job crafting.

Empirical antibiotics for recurrent urinary tract infections in children

  • Choi, Hyun Gil;Lee, Ji Young;Oh, Chi Eun
    • Kosin Medical Journal
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    • v.33 no.2
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    • pp.159-170
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    • 2018
  • Objectives: The purpose of this study was to compare antibiotic resistance patterns between first urinary tract infection (UTI) and recurrent UTI groups and to obtain information regarding empirical antibiotic selection for treating recurrent UTI. Methods: We retrospectively reviewed 148 children treated for UTIs from January 2009 to June 2016. The patients were divided into two groups: first UTI (N = 148) and recurrent UTI (17 patients and 20 episodes). Results: In both groups, Escherichia coli was the most frequent causative organism, accounting for 89.9% and 75.0% in the first and recurrent UTI groups, respectively. When E. coli or Klebsiella pneumoniae was the causative organism, extended-spectrum ${\beta}-lactamase$ (ESBL)-producing organisms were more frequent in the recurrent UTI group (17.6%) than in the first UTI group (14.0%); however, this difference was not statistically significant (P = 0.684). Cefotaxime was the most frequently used first-line empirical antibiotic in both groups. In the first UTI and recurrent UTI groups, 7.4% and 15.0% of patients were treated with intravenous antibiotics as definitive therapy, respectively (P = 0.250). Fifteen out of 17 patients having a second UTI had different causative organisms or antibiotic susceptibility patterns compared to their previous episode. Conclusions: Escherichia coli was the most frequent causative organism in the recurrent UTI group. There were no differences in the proportion of ESBL-producing organisms between the first UTI and recurrent UTI groups. Therefore, when a UTI recurs in children, the antibiotics effective on the most common causative organism might be administered as empirical antibiotics.

Design and Implementation of Turbidity Measurement Module of Plume using Optical Sensing (광학센싱을 이용한 굴뚝연기의 혼탁도 측정모듈의 설계 및 구현)

  • Ban, ChaeHoon;Son, HyunGeun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.05a
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    • pp.312-315
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    • 2014
  • Smoke generated from business establishments and factories will not only cause air pollution but also have a significant impact on the human body. Generally, the most common method for measuring the turbidity of the plume generated from the stack is a method of observing by the transmissometer mounted in the chimney or Method 9 from the US EPA(Environmental Protection Agency) which is a visual method of determining plume turbid emitted from stationary sources. However, these methods need a lot of cost to build and maintain. In this paper, we build a plume turbidity measurement module programs using light sensing. We design and implement a module which acquires the pictures of the plume using a digital camera and measures the turbidity of it using the DOM(Digital Optical Method). In addition, we demonstrate the excellence by comparing and analyzing implemented module and other methods.

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The Development and Evaluation of a Health Literacy-Adapted Self-Management Intervention for Elderly Cancer Patients Undergoing Chemotherapy (노인 암환자의 건강정보 이해능력을 반영한 항암화학요법 자기관리 프로그램 개발 및 평가)

  • Kim, Yoon Sun;Tae, Young Sook;Jung, Kwuy-Im
    • Journal of Korean Academy of Nursing
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    • v.49 no.4
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    • pp.472-485
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    • 2019
  • Purpose: This study aimed to develop and evaluate the effectiveness of an adapted health literacy self-management intervention for elderly cancer patients undergoing chemotherapy. Methods: The intervention in this study was systematically developed through the six stages of Intervention Mapping Protocol and was based on Fransen et al's causal pathway model. A quasi-experimental trial was conducted on a total of 52 elderly patients (26 in an experimental group and 26 in a control group) undergoing chemotherapy in Korea. The intervention consisted of seven sessions over 5 weeks. The experimental tool for this study was an adapted health literacy self-management intervention, which was designed to promote a reduction in the symptom experience and distress of elderly cancer patients through the promotion of self-management behavior. To develop efficient educational materials, the participants' health literacy was measured. To educate participants, clear communication and the teach-back method were used. In addition, for the improvement of self-efficacy, four sources were utilized. For the promotion of self-management behavior, five self-management skills were strengthened. Data were collected before and after the intervention from June 4 to September 14, 2018. The data were analyzed with SPSS/WIN 21.0. Results: Following the intervention, self-management knowledge and behavior and, self-efficacy significantly improved in experimental group. Symptom experience and distress decreased in the experimental group compared to the control group. Conclusion: The self-management intervention presented in this study was found to be effective in increasing self-management knowledge and behavior and, self-efficacy, and ultimately in reducing symptom experience and distress for elderly patients undergoing chemotherapy.

A Convergence Study on the Use of Music for Job Stress of Employees in Highway Service Areas (고속도로휴게소 종사자의 직무스트레스에 따른 음악활용 융합연구)

  • Lee, Seon-Jeong;Park, Hye-Young
    • Journal of the Korea Convergence Society
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    • v.10 no.5
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    • pp.239-248
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    • 2019
  • The purpose of this study was to examine the use of music for job stress of employees in highway service areas and differences in use of music. For this, a survey was conducted on 150 respondents of U city and G province. The questionnaires were composed of a total of 53 questions, including use of music 25, job stress 24, and demographic characteristics 4 questions. A total of 150 questionnaires were distributed and 134 were analyzed. As a result, first, the respondents preferred listening to music over playing instruments or singing and mostly listened to popular music at home alone. Second, they reported that their purpose of use of music was for mood change followed by comfort, joy, sense of vigor, and sense of relief. Third, there were significant differences in mood of music and degree of achieving sense of relief through music. This study could provide information for organizing effective convergence music programs which could meet the needs and demands of them.

Relation of Various Parameters Used to Estimate Cardiac Vagal Activity and Validity of pNN50 in Anesthetized Humans

  • Lee, Jae Ho;Huh, In Young;Lee, Jae Min;Lee, Hyung Kwan;Han, Il Sang;Kang, Ho Jun
    • Kosin Medical Journal
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    • v.33 no.3
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    • pp.369-379
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    • 2018
  • Objectives: Analysis of heart rate variability (HRV) has been used as a measure of cardiac autonomic function. According to the pNN50 statistic, the percentage of differences between successive normal RR intervals (RRI) that exceed 50 ms, has been known to reflect cardiac vagal modulation. Relatively little is known about the validity of pNN50 during general anesthesia (GA). Therefore, we evaluated the correlation of pNN50 with other variables such as HF, RMSSD, SD1 of HRV reflecting the vagal tone, and examined the validity of pNN50 in anesthetized patients. Methods: We assessed changes in RRI, pNN50, root mean square of successive differences of RRI (RMSSD), high frequency (HF) and standard deviation 1 (SD1) of $Poincar{\acute{e}}$ plots after GA using sevoflurane anesthesia. We also calculated the probability distributions for the family of pNNx statistics (x: 2-50 ms). Results: All HRV variables were significantly decreased during GA. HF power was not correlated with pNN50 during GA (r = 0.096, P = 0.392). Less than pNN47 was shown to have a correlation with other variables. Conclusions: These data suggest that pNN50 can not reflect the level of vagal tone during GA.