• Korean Journal of Clinical Laboratory Science
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• v.51 no.3
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• pp.286-293
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• 2019

Hypertension (HTN) is one of the major chronic diseases, and HTN is defined as being in a state of continuous high blood pressure. Left ventricular hypertrophy (LVH) is a condition in which the mass of the left ventricle has increased, and HTN is a leading cause of LVH. HTN and LVH are known to be caused by the interaction of environmental factors and genetic factors. It has been reported that the polymorphisms of SLC8A1, among the genetic factors that affect high blood pressure, are related to salt sensitivity hypertension. In this study, the genetic polymorphisms of SLC8A1 were chosen based on the Korean Genome and Epidemiology data. Logistic regression analysis was then performed for HTN and LVH. Linear regression analysis was also performed for systolic blood pressure (SBP) and diastolic blood pressure (DBP). As a result, 5 SNPs showed statistically significant associations (P<0.05) with HTN, and 10 SNPs showed statistically significant associations with LVH. rs1002671 and rs9789739 showed significant correlation at the same time with HTN and LVH. These results suggest that the polymorphisms of the SLC8A1 gene are linked to the development of HTN and LVH in Koreans. We expect these results to help us understand the pathogenic mechanisms for HTN and LVH.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.31 no.5
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• pp.241-252
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• 2019

To choose appropriate countermeasures against potential coastal disaster damages caused by a storm surge, it is necessary to estimate the frequency of storm surge heights estimation. As the coastal populations size in the past was small, the tropical cyclone risk model (TCRM) was used to generate 176,689 synthetic typhoons. In simulation, historical paths and central pressures were incorporated as a probability density function. Moreover, to consider the typhoon characteristics that resurfaced or decayed after landfall on the southeast coast of China, incorporated the shift angle of the historical typhoon as a function of the probability density function and applied it as a damping parameter. Thus, the passing rate of typhoons moving from the southeast coast of China to the south coast has improved. The characteristics of the typhoon were analyzed from the historical typhoon information using correlations between the central pressure, maximum wind speed ($V_{max}$) and the maximum wind speed radius ($R_{max}$); it was then applied to synthetic typhoons. The storm surges were calculated using the ADCIRC model, considering both tidal and synthetic typhoons using automated Perl script. The storm surges caused by the probabilistic synthetic typhoons appear similar to the recorded storm surges, therefore this proposed scheme can be applied to the storm surge simulations. Based on these results, extreme values were calculated using the Generalized Extreme Value (GEV) method, and as a result, the 100-year return period storm surge was found to be satisfactory compared with the calculated empirical simulation value. The method proposed in this study can be applied to estimate the frequency of storm surges in coastal areas.

• Journal of Korea Entertainment Industry Association
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• v.15 no.8
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• pp.351-361
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• 2021

This study was conducted to identify the factors of hypertension treatment in Gwangju and to establish a hypertension cure rate management plan by using local community health surveys to provide the hypertension cure rate management plan centering around the wellness local community. The research collected 13,714 Gwangju research data among a total of 685,820 local community health surveys of KDCA (Korea Disease Control and Prevention Agency) from 2017 to 2019. Among the data, 2,941 subjects, those with diagnosed hypertension aged over 30, were selected and analyzed through SAS 9.4, SAS Enterprise Miner 15.1. The results are as follows. The differences in hypertension diagnosis cure rate in Gwangju based on the subjects' socioeconomic characteristics were shown in gender, age, marital status, level of educational attainment, economic activity status, and monthly income. The significant differences in hypertension cure rate based on health behavior characteristics were shown in current smoking, monthly alcohol consumption, high-risk drinking, breakfast, recognition of good health level, diabetes and treatment, annual unmet medical needs, and annual health center use. As a result of the logistic regression analysis and interactive decision tree analysis to identify the factors affecting hypertension treatment, the research found that the factors that appear are age, marital status, diabetes and treatment, and annual unmet medical needs. Accordingly, to increase the recognition of the importance of hypertension treatment to people of young ages and not to develop complications, public health-educational effort in Gwangju is needed with an effective preparation plan.

• 한국노년학
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• v.29 no.1
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• pp.135-147
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• 2009

Recently, The number of hypertension is increasing with westernized diet and lack of exercise. Many researchers are trying to treat and prevent hypertension by exercise therapy. However, not only did most of studies analyze the effect and usefulness of exercise related to lowering hypertension, but also there is no analysis of the difference of fitness with regard to hypertension according to ages. It is assumed to be important research work to be continued to identify, from the public health's point of view, the difference of fitness with regard to hypertension according to ages can be a essential data for treating and preventing hypertension. Thus, this study is to identify the difference of fitness according to hypertension of adult female over 20s and emphasize the importance of fitness level to the hypertension. Also, this study is to devise valuable study by examining the difference of cardiovascular function. Subjects were 8889 of adult female over 20s. Subjects visited promotion of health center at Y Gu public health center and took comprehensive medical test including hypertension test in Seoul in Korea. It was divided into normal, prehypertension, stage I hypertension and stage II hypertension group by JNC7. The evaluation of cardiorespiratory function was by resting heart rate and lung capacity, the evaluation of fitness was by cardiorespiratory endurance, muscular endurance, muscular strength, power, agility, balance, and flexibility, and the difference of fitness was analyzed by ANCOVA revising independent variable of BMI, drinking, and smoking which affects hypertension. At result, there was significant difference between normal and hypertension group according to most ages in two variable of all cardiorespiratory function, seven fitness variable. Through this study, it was defined that hypertension group had lower cardiorespiratory function and fitness than normal group.

• 레미콘
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• no.10 s.73
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• pp.36-54
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• 2002

• 레미콘
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• no.4 s.71
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• pp.18-27
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• 2002

• 레미콘
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• no.4 s.71
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• pp.44-56
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• 2002

• 레미콘
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• no.4 s.87
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• pp.44-50
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• 2006

• 발명특허
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• v.13 no.8 s.150
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• pp.68-71
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• 1988

• 비료회보
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• s.90
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• pp.16-22
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• 1978