• Proceedings of the Korean Society of Computer Information Conference
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• 2022.07a
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• pp.307-310
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• 2022

4차 산업혁명의 기술이 발전함에 따라 세계는 눈부시게 발전하고 있다. 그러나 그와 동시에 어르신들의 치매로 인한 사회적 비용의 증가로 발생하는 문제점 또한 무시하지 못할 수준에 이르렀다. 이에 조기에 치매를 선별하여 예방하는 것이 중요시되었으며 다양한 연구기관에서는 빠르고 쉽게 치매의 전 단계인 경도인지장애를 선별하고자 여러 선별 검사지를 제작하여 경도인지장애 선별을 통한 치매를 예방하는 데 노력하는 중이다. 하지만 다양한 상황으로 각각의 효율성이 경도인지장애 선별에 대한 기대에 미치지 못하고 있다. 그리하여 본 연구는 기존에 개발된 경도인지장애 선별지 들을 비교 분석 및 코로나 상황에 적합하게 비대면 방식으로 경도인지장애 선별이 가능하도록 보다 효율적으로 개선하였으며 이를 IoT 기기에 접목하였다. 또한 IoT 기기는 어르신들의 경도인지장애 선별검사에 대한 부담감을 줄이고자 친근한 인형 형태로 개발하였으며 상호작용을 위한 기능 제작을 통하여 마음 돌봄 서비스를 구현하였다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2022.07a
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• pp.61-62
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• 2022

알츠하이머성 치매는 현존하는 치료법이 없어 경도인지장애 단계에서의 예방이 중요하다. 지금까지의 알츠하이머 연구는 대부분이 뇌영상 마커와 뇌척수액 마커에 집중되어 있었으며, 경도 인지 장애 단계에서의 탐색은 더욱 적었다. 이러한 점에서 혈액 유전자 발현을 이용한 경도 인지장애 단계 예측은 인지 능력에 따른 관련 유전자 식별과 접근 가능한 진단 및 치료 바이오 마커 탐색에 기여할 수 있다. 그러나 유전자 발현 데이터의 경우 환자 수에 비해 높은 차원을 가지기 때문에 과적합을 막고 질병 관련 유전자를 식별하기 위해서는 데이터에서의 의미 있는 차원만을 뽑아내는 차원 축소가 선행되야 한다. 본 연구는 유전자 발현데이터에서의 인지장애 분류를 위해 차원 축소기법과 신경망을 적용하여 인지 장애 정도를 예측하였다. 그 결과, Lasso 이용 차원축소와 신경망을 이용하여 97%의 정확도로 정상과 조기 경도 인지장애, 후기 경도 인지장애 환자를 분류 할 수 있었으며, 더 적은 차원에서도 분류가 가능했다. 이는 혈액 유전자 발현을 이용해 경도 인지장애 단계를 예측한 첫 번째 연구이며, 인지능력 저하에 따른 혈액 유전자 발현의 연관성을 확인하고 향후 조기 진단, 치료 표적 탐색에 기여한다.

• Therapeutic Science for Rehabilitation
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• v.7 no.4
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• pp.31-41
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• 2018

Objective: This study was to develop computerized screening test items for mild cognitive impairment. Methods: Through literature reviews, items from computerized tests for screening mild cognitive impairment were extracted. A panel of professional experts validated that the items were important and fit to screen for mild cognitive impairment. Results: A total 37 items were extracted from 12 computerized tests and 11 new items were added through the first panel review. After that, 18 items were removed via the second panel review. Finally, 16 items were selected by analyzing content validity ratio. 16 items consisted of memory, attention, and executive function areas. Conclusions: A total of 16 computerized test items were developed. It is urgent to validate them to screen mild cognitive impairment. Moreover, standardization studies for this test are required in the future.

• Journal of the Korea Convergence Society
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• v.8 no.5
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• pp.243-253
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• 2017

The purpose of this study is to provide evidences for developing non-pharmacological intervention program in elderly patients with mild cognitive impairment by integrative review and analyze. An integrative review concept analysis method was used. According to the study result, relevant studies were 11, which are related to non-pharmacological intervention program in elderly patients with mild cognitive impairment. The quality of stduies were two groups nonrandomized studies were 9, and one group nonrandomized studies were 2. Non-pharmacological intervention program studies for elderly patients with mild cognitive impairment were 4 in cognitive training program, 6 in exercise program, and 1 in music program. The efficacy of non-pharmacological intervention in elderly patients with mild cognitive impairment was different by studies, and we need further studies based on these study results.

• Therapeutic Science for Rehabilitation
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• v.2 no.2
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• pp.37-45
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• 2013

This research reviewed the instrumental ADL for patients with mild cognitive impairment, which is one of the most interested topics, and hope that this research helps evaluating and treating the mid cognitive impairment patients in occupational therapy. The treatment for dementia patients are actively in progress, but there has not been treatment approach about mild cognitive impairment patients, who are in risk of moving on to dementia. In this review, we have dealt with the foundation of matching the point to instrumental ADL from the occupational areas of mild cognitive impairment patients and normal elders. We have discussed the that essential consideration about instrumental ADL is needed to prevent mild cognitive impairment developing into dementia. In conclusion, there is a need of regular evaluation about instrumental ADL considering the occupational areas of mild cognitive impairment patient groups, who are highly in risk of developing into dementia, and occupational therapeutic approach is needed as well.

• Journal of the Korean Applied Science and Technology
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• v.38 no.2
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• pp.511-520
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• 2021

This study was a pre and post quasi-experimental design study using a single group about the analysis of the changes in the performance level of activities of daily living and depression of the elderly with mild cognitive impairment through the participation in the cognitive program. Study subjects were the 16 elderly with mild cognitive impairment using a W welfare center in J city and they participated in cognitive program for a total of 8 weeks, twice a week. The assessment about the performance level of activities of daily living and depression were performed through the program. As the results, after participating in the program, study subjects' performance level of activities of daily living were significantly significant improved, and depression levels were statistically significantly reduced. Thus, to improve the performance level of activities of daily living and reduce the depression levels of the elderly with mild cognitive impairment, the cognitive program should be used as a intervention program and then in the process, it is necessary to actively induce the participation of the elderly with mild cognitive impairment.

• Journal of the Korea Convergence Society
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• v.12 no.2
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• pp.327-336
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• 2021

It is important to prevent progression of mild cognitive impairment (MCI) to Alzheimer's disease or other dementia. This study was conducted to investigate cognitive-based intervention and its effectiveness for the older patients with MCI through systematic review. Data search was conducted in September 2020, using the Korea Research Information Service (Riss) and KoreaMed. After selection of literatures according to the predefined inclusion criteria, a total of 12 articles were included. It is revealed that the cognitive-based intervention for the older adults with MCI was found to have a positive effect on the various factors including cognitive function, depression, physical health status, quality of life, and communication. However, it is difficult to draw a definite conclusion due to the various intervention strategies and instruments used. Thus, based on the results of this study, we suggest more studies to verify the effectiveness of such programs.

• Journal of Digital Convergence
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• v.17 no.2
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• pp.283-292
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• 2019

The loss of semantic knowledge and impairments in semantic associations by semantic category is gaining increasing attention, as indicators of early-stage cognitive decline. As such, we assigned semantic association task (SAT) to normal elderly (NE) and those with subjective memory impairment (SMI) or mild cognitive impairment (MCI) to examine their performance by semantic subcategories and the differences in error patterns. We found a significant difference in the number of correct response and reaction time under the SAT categories among the three groups, with the highest performance observed in 'function' and the lowest performance in 'superordinate' and 'part/whole'. Moreover, the error frequency was the lowest in NE, followed by those with SMI and MCI, with the latter two groups showing a significant increase in no-response. Our findings demonstrate the varying extent and process of impairments in the semantic network by category over different stages of cognitive decline. Thus, we proposed SAT performance as an indicator to detect and follow-up on cognitive decline in elderly with cognitive disorder.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.178-185
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• 2018

A self-report evaluation is used to prevent driving accidents by elderly drivers. The majority of normal older adults may have mild cognitive impairment with reduced cognitive function. These depressed cognitive functions may be variables that affect the performance of elderly drivers. This study confirmed the cognitive functions that affect the self-reported evaluation for elderly drivers with mild cognitive impairment. Based on the results of the Korean Version of the Montreal Cognitive Assessment, 103 elderly drivers were classified into mild cognitive impairment and normal groups of elderly drivers. The Korean-Drivers 65 plus scores used in the self-reported evaluation of the two groups were compared, and the cognitive functions affecting the evaluation were analyzed. Results found the mild cognitive impairment group showed a significantly lower evaluation performance compared to the normal group, and the self-reported evaluation results of the elderly driver with mild cognitive impairment showed a significant correlation between visuoconstructional skills and delayed recall. As a result of regression analysis, the visuoconstructional skill was identified as the cognitive function with the strongest influence on the self-reported evaluation performance. Delayed recall was also found to have a partial effect but not at the level of altering the self-reported evaluation results of the elderly driver with mild cognitive impairment.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.551-556
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• 2023

This study was attempted to confirm whether the color therapy intervention study on the elderly with mild cognitive impairment was effective in cognitive function and depression as a method of meta-analysis. In this study, the size of the effect of cognitive function and depression on the final eight studies of the experimental study was calculated through a domestic database from 2000 to October 2022. As a result, the statistically significant average effect size of the entire study was confirmed. In the test of the difference in effect size between groups, both cognitive function and depression were found to have significant effect sizes. Through this study, it was confirmed that calerotherapy is an effective intervention that can improve cognitive function and alleviate depression in the elderly with mild cognitive impairment. Based on the results of this study, it is necessary to develop an intervention program for the elderly with mild cognitive impairment using calerotherapy.