• Clinical and Experimental Pediatrics
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• v.50 no.12
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• pp.1188-1193
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• 2007

Purpose : The prevalence of rickets in the world is on the rise not only in developing but also in developed countries. In Korea, breastfeeding has increased. There have been few studies on the possible association of rickets with breastfeeding. The purpose of this study was to identify the development and the clinical presentation of subclinical rickets in breastfed infants. Methods : We investigated patients who were breastfed and had hypovitaminosis D in the blood from May 2006 to April 2007, and who were diagnosed with vitamin D deficient rickets from May 2003 to April 2006. We evaluated the results of blood tests, x-rays and other relevant information in the medical record. A questionnaire that included questions on the diet of patients, the mothers activity during pregnancy and place of residence was administered. Results : Twelve patients (66%: male, 34%: female) were enrolled in this study. There were eight in the asymptomatic and four in the symptomatic group. The median age for each group was 8 months (range 4-11 month) and 5.5 months (5-8 month). All patients in the symptomatic group were breastfed until diagnosed. In the asymptomatic group, they were breastfed for four to six months, and then weaned with only thin rice soup and vegetables. Nine patients had a vitamin D concentration below 20 ng/mL and three patients had levels between 20 and 29 ng/mL. Alkaline phosphatase (ALP) and parathyroid hormone (PTH) were elevated in both groups. There were statistically significant $25-OHD_3$ levels in the blood in both groups (P=0.008). Ten of the patients (83%) also had iron deficient anemia. Conclusion : Vitamin D deficiency and subclinical rickets has been identified in Korea. However, the prevalence of this disease has not been determined. The main limitation of this study was the small number of patients and the absence of a control group.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.11 no.1
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• pp.103-105
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• 2011

고호모시스틴혈증(hyperhomocysteinemia)은 호모시스테인과 메티오닌의 대사과정에 관여하는 여러 효소들의 결핍에 의해 발생할 수 있으며, 대표적인 효소 결핍으로는 cysthathione beta-synthase (CBS) 결핍증, Methionine synthase (MS) 결핍증, methylenetetrahydrofolate reductase (MTHFR) 결핍증이 있다. 이들은 고호모시스테인혈증을 보이나 임상증상, 메티오닌의 동반 상승, 거대적아구성빈혈, 메칠말로닌산뇨증등의 동반 여부등을 토대로 감별진단에 도움을 받을 수 있다. 본 연자는 뇌혈전증과 뇌졸중을 동반하는 고호모시스테인혈증의 원인으로 MTHFR 유전자의 돌연변이를 발견한 증례를 경험하였기에 이를 보고하는 바이다.

• The Journal of the Korea Contents Association
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• v.16 no.7
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• pp.291-299
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• 2016

This study aimed to evaluate the relationship of ADHD, depression, anxiety, self-esteem, impulsivity, suicide idea and quality of life as well as burnout of kindergarten teachers for the first time in Korea. Also, it examined the odds ratio with ADHD, depression, anxiety, self-esteem, impulsivity, suicide idea and quality of life between burnout group and the comparison group through logistic regression analysis. A set of questionnaires was provided to a total of 310 participants (80 with higher burnout risk and 230 without burnout risk) from April 2015 to July 2015. All of participants were evaluated using the Korean Adult Attention Deficit Hyperactivity Disorder Scales, Beck's Depression Inventory, Beck's Anxiety Inventory, Baratte' Impulsivity Scale, Rosenberg's Self-esteem Inventory and Qulity of Life Scale. The results of this study indicated that burnout risk group is related to ADHD and anxiety and impulsivity. For the treatment of burnout in kindergarten teachers, effective evaluation and treatment of ADHD and impulsivity, as well as anxiety, seem to be necessary.

• Journal of the korean veterinary medical association
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• v.41 no.7
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• pp.625-627
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• 2005

• The Journal of the Korea Contents Association
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• v.12 no.10
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• pp.330-339
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• 2012

The purpose of this study was to examine the relationship among children's ADHD symptoms, parenting stress and behavior regarding nurturing. The data were provided by 59 mothers of children with ADHD who is aged between 4 and 12. Mothers of children with ADHD were recruited through 3 departments of child psychiatry. The Korean version of Parenting Stress Index-Short Form, the Korean version of revised Maternal Behavior research Instrument(MBRI) and ADHD Rating Scale(K-ARS) was used to assess parenting stress, behavior regarding nurturing and ADHD symptoms respectively. Significant correlation was found between parental distress and warmth, rejection behavior. Parental distress is significant influence on behavior regarding nurturing through multiple regression analysis. Significant correlation was found between ADHD symptom and rejection behavior. ADHD symptom is significant influence on behavior regarding nurturing through multiple regression analysis. Behavior regarding nurturing is related to ADHD symptom, parental distress. Therefore, it is needed for not only treatment related to ADHD symptom but also interventions for behavior regarding nurturing for mothers of children with ADHD.

• Journal of the Korea Convergence Society
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• v.9 no.7
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• pp.337-346
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• 2018

The purpose of this study was to identify the characteristics and the attributes related to Internet use in patients with Internet addiction. This study is a descriptive secondary analysis study, at Internet addiction clinics used the data of 63 patients diagnosed with Internet addiction. Data were obtained from Internet addiction clinic Electronic Medical Records(EMR), there was included the Korean Internet addiction scale(K-scale), Beck Anxiety Inventory(BAI), Beck Depression Inventory(BDI), Barratt Impulsivity scale(BIS), Conners ADHD Rating Scale(CAARS), Lubben Social Network Scale(LSNS). K-scale had significantly correlations with Internet use time per day, anxiety, impulsivity, Attention deficit Hyperactivity Disorder(ADHD) symptom. In stepwise multiple regression, factors significantly affecting ADHD symptom (${\beta}=.37$), Internet use time per day(${\beta}=.29$), Impulsivity(${\beta}=.25$), which accounted for 44% of the variance. Results indicate that patients with Internet addiction had psychological difficulties and suggest that children with ADHD needed to intervention for appropriate internet use.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.1
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• pp.35-39
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• 2015

Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most common mitochondrial fatty acid oxidation disorder which is inherited as an autosomal recessive pattern. MCAD deficiency is caused by mutations in the ACADM gene; medium-chain acyl-CoA dehydrogenase gene (ACADM; OMIM 607008) on chromosome 1p31 which encodes MCAD, the mitochondrial enzyme which catalyzes the first reaction in beta-oxidation of fatty acids with medium-chain length. Here, we describe one Korean pediatric case of MCAD deficiency, which was diagnosed during newborn screening by tandem mass spectrometry and confirmed by molecular analysis. The level of hexanoyl (C6), octanoyl (C8), decenoyl (C10:1) carnitine, and C8/C2 ratio was elevated. Homogenous c.1189T>A (p.Tyr397Asn) mutation of ACADM gene was identified by direct sequencing. He has been asymptomatic and has shown normal growth and development by 25 months of age without any intervention. There was no episode of metabolic acidosis during follow-up period.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.10 no.1
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• pp.91-99
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• 1999

Objects：It is difficult to differentiate between attention deficit hyperactivity disorder(ADHD) and mania because of similar symptoms and atypical symptoms of mania in children and adolescents. The purpose of this study is to identify the characteristics and to clarify the relationship by comparing the clinical features and comorbidities of ADHD and manic patients. Methods：The subjects consisted of 35 patients with ADHD and 19 manic patients. To Compare the characteristic symptoms between the two disorders, we selected 29 patients with ADHD and 14 patients with manic disorders. 6 ADHD patients who had manic disorders as comorbid disorder, and 5 manic patients who had ADHD as comorbid disorders were manic disorders were excluded. Results：1) There were significant differences in ages of onset and state anxiety scale scores, birth weights, numbers of perinatal problem, gestational ages, school behavioral problems between ADHD patients and manic patients(p<0.01). 2) There were significant differences in loses things(p<0.05) of ADHD-symptoms and grandiosity(p<0.01), decrease in sleep(p<0.05), delusions(p<0.01), hallucinations(p<0.05) of mania-symptoms between ADHD patients and manic patients. 3) The comorbid disorders of ADHD patients are significantly high(p<.05) than that of manic patients in major depression. 4) The familial loading of manic patients are significantly high(p<.05) than that of ADHD patients in mood disorder. Conclusions：The above results suggest that ADHD and mania are different disorders, considering the significant differences of clinical features and characteristics, familial loadings of the two disorders.

• Journal of the korean veterinary medical association
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• v.23 no.5
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• pp.337-339
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• 1987

모낭충은 거의 모든개 - 건강한 개일지라도 - 감염되어 있다. 그러나 모낭충증은 일차적으로 세포성 면역에 결핍이 있거나 외부적 영향에 의해 면역계가 악화된 개에서만 임상증상으로 진전된다. 특별한 T-lymphocytes 자극물질은 단독 투여하든지 또는 살충제와 병용해 사용함으로써 모낭충의 치료에 이용할 수 있다.

• Journal of Digital Convergence
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• v.12 no.6
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• pp.145-154
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• 2014

ADHD is a neuro-developmental disorder that begins in childhood, yet may continue into adulthood. Although 3 to 4 percent of adults are affected by ADHD, but only a small proportion of adults ever receive a formal diagnosis and treatment. The core symptoms of ADHD frequently lead to significant academic difficulties that often result in the students' teacher being the first to suspect the disorder. In order for school teachers to effectively deal with ADHD students in school classrooms, they need to have positive attitude toward ADHD students. This study presents a list of ADHD-related web sites which provide educational contents and support for school teachers, and provides the discussions about the current status and the roles of those web sites.