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The comparison of the frictional force by the type and angle of orthodontic bracket and the coated or non-coated feature of archwire (교정용 브라켓의 종류와 각도, 호선의 코팅 여부에 따른 마찰력의 비교)

  • Jang, Tae-Ho;Kim, Sang-Cheol;Cho, Jin-Hyoung;Chae, Jong-Moon;Chang, Na-Young;Kang, Kyung-Hwa
    • The korean journal of orthodontics
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    • v.41 no.6
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    • pp.399-410
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    • 2011
  • Objective: The purpose of this study was to evaluate the difference in frictional resistance among metal, ceramic, self-ligation brackets and coated or non-coated Ni-Ti archwires at various bracket-archwire angulations during the sliding movement of an orthodontic archwire, using an orthodontic sliding simulation device. Methods: Four types of bracket (Micro-arch Perpect Clear2 Clippy-C and Damon3 and 5 types of orthodontic archwire (0.014", 0.016", and 0.016" ${\times}$ 0.022" inch coated Ni-Ti, and 0.016" and 0.016" ${\times}$ 0.022" inch Ni-Ti) were used. Further, the bracket- archwire angles were set at 4 different angulations: $0^{\circ}$, $3^{\circ}$, $6^{\circ}$, and $9^{\circ}$. Results: The frictions from all the experimental groups were found to be significantly increased in order of self-ligation brackets, Micro-arch and Perpect Clear2 ($p$ < 0.001). The presence of a coat had no effect on the friction of the same sized archwires at $0^{\circ}$ and $3^{\circ}$ bracket-archwire angles ($p$ < 0.001). Coated archwires had significantly higher frictions than the same sized non-coated archwires at $6^{\circ}$ and $9^{\circ}$ bracket-archwire angles ($p$ < 0.001). The frictions increased significantly as the bracket-archwire angles were increased ($p$ < 0.001). Conclusions: The use of self-ligation brackets will be beneficial in clinical situations where a low frictional force is required. Further, in cases where crowding is not severe, the use of coated archwires should not cause problems. However, more additional explanation is required considering the fact that the damage of coated archwire and exposure of the metal portion in case of binding and notching and the effects of saliva were not taken into account.

Lymphangioleiomyomatosis with Bilateral Chylothorax -1 case report- (양측 유미흉을 동반한 림프관평활근종증)

  • 김시욱;최재성;나명훈;임승평;이영;유재현
    • Journal of Chest Surgery
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    • v.37 no.12
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    • pp.1029-1031
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    • 2004
  • We had expierienced pulmonary lymphangioleiomyomatosis(LAM) with bilateral chylothorax and chylous ascites. A twenty-one-year-old lass with chief complaint of abdominal pain was admitted through the emergency room. She received emergent pelvicoscopic surgery for the rupture of the right corpus luteum. We aspirated 1000ml of the uncoagulated blood. The bleeding point was cautherized electrically. LAM was diagnosed with tissue from the retroperitoneum. Chylous ascites and bilateral chylothorax were occurred despite of various treatments. On thoracotomy, bullous changed lung and lymphatic leakage from visceral and parietal pleura were observed. She died of respiratory insufficiency and general weakness after 6 months from admission.

Inulin Space in the Abdominal Vena Cava Partially Ligated Rabbits (복부하공정맥 결찰동물의 Inulin space)

  • Lee, Jeoung-Ku;Im, Hae-Jung;Choi, Duck-Kyung
    • The Korean Journal of Physiology
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    • v.8 no.2
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    • pp.55-58
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    • 1974
  • Inulin space was measured in the normal control rabbits and abdominal vena cava partially ligated (to about 1/2 of normal lumen) rabbits. Eleven rabbits served as the control and 12 rabbits after 7 to 10 days of abdominal vena cava ligation were used. Inulin space in the normal rabbits was $376{\pm}102.70\;ml\;(Mean{\pm}S.D.)\;or\;18.0{\pm}5.21%$ body weight. After 7 to 10 days of abdominal vena cava partial ligation inulin space decreased and the values were; $253{\pm}145.79\;ml\;or\;14.4{\pm}8.55%$ body weight.

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A Study About Biochip Combined with Micro Mixer and Reactor for DNA Ligation (마이크로 혼합기와 반응기로 구성된 DNA 결찰용 바이오칩에 관한 연구)

  • Kang, Do-Hyoung;Ahn, Yoo-Min;Hwang, Seung-Yong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.32 no.8
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    • pp.624-632
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    • 2008
  • In this research, we developed new PDMS-glass based microbiochip consisted of the micromixer and microreactor for DNA ligation. The micromixer was composed of a straight channel integrated with nozzles and pillars, and the microreactor was composed of a serpentine channel. We coated the PDMS chip surface with the 0.25wt.% PVP solution to prevent the bubble generation which was caused by the hydrophobicity of the PDMS. The new micomixer was passive type and the mixing was enhanced by a convective diffusion using the nozzle and pillar. The 10.33mm long micromixer showed the good mixing efficiency of 87.7% at 500 l/min flow rate. We could perform the DNA ligation successfully in the microbiochip, and the ligation time was shortened from 4 hours in conventional laboratory method to 5 min in the microbiochip.

Effects of Bupleuri Radix on Rat Hepatic COMT by Common Bile Duct Ligation and Taurocholate Load after Common Bile Duct Ligation (시호가 총담관결찰 및 Taurocholate 부하 흰쥐 간의 COMT 활성에 미치는 영향)

  • 김승모;윤주현;박재현
    • The Journal of Korean Medicine
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    • v.21 no.3
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    • pp.68-76
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    • 2000
  • Object : This study was earned out to examine the effect of Bupleuri Radix on experimental cholestasis, and make clear a part of this mechanism. Methods : Two models of common bile duct ligation group and taurocholate load group after common bile duct ligation were induced, and Bupleuri Radix extract was taken orally for 14 days. In the 1, 2, 4, 7 and l4days after treatment, cytosolic, mitochondrial and microsomal catechol-O-methyltransferase(COMT) activities in liver were measured. Results : The activities of cytosolic, mitochondrial and microsomal COMT increased in the Blupleuri Radix treated group after common bile duct ligation and after taurocholate load and common bile duct ligation. The activities of cytosolic and mitochondrial COMT increased particularly in Blupleuri Radix treated group after taurocholate load and common bile duct ligation. Conclusions : According to the result, it is considered that Blupleuri Radix not only improves cholestatis in liver, but also decreases a genetic synthesis of taurocholic acid.

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새로운 오메프라졸염의 약효검색에 관한 연구

  • 이영근;이송득;김승희;박윤주;강석연
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.302-302
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    • 1994
  • 오메프라졸의 산 불안정성을 개선하기 위하여 신규 합성한 오메프라졸 cholestyramin resin 염 복합체와 오메프라졸 hydroxypropyl-$\beta$-cyclodextrin (HP-$\beta$-CD) 포접화합물의 약효를 검색하였다. 생체외 실험 (in vitro test)으로 H$^{+}$/K$^{+}$-ATPase 활성도 저해효과를 검토하였으며 생체내 실험 (in vivo test)으로 Shay 결찰법에 의한 위산분비 억제효과에 대한 실험을 실시하였다. 오메프라종 염 복합체와 오매프라졸 포접화합물은 1$\times$$10^{-5}$-1$\times$$10^{-3}$M농도 범위에서 용랴의존적으로 H$^{+}$K$^{+}$-ATPase 활성을 억제시켰으며 $IC_{50}$/치는 오메프라졸 결과와 유사하였다. 셍체네 실험에서는 오메프라졸 HP-$\beta$-CD 포접화합물이 오메프라졸과 그 resin염복합체보다 위액분비량, 펩신 활성도에 대한 $IC_{50}$/치가 낮았으며 이는 생체내에서 포접 화합물이 오메프라졸의 안정성을 증가시킴으로서 위산분비 억제효과를 증가시킨것으로 사료된다.

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간장질환 치료제 G09의 개발 - 물성및 약리연구

  • Kim, Soo-Woong;Lee, Seung-Ryong;Jung, Hoon;Park, Man-Ki;Park, Jung-Il;Kim, Jae-Baek;Son, Dong-Hwan;Jung, Jin-Ho;Ko, Kwang-Ho
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.168-168
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    • 1994
  • G009는 단백다당체로서 분자량 0.5-200만 사이에 광범위하게 분포되어 있으며 구성당은 glucose를 주로하여 galactose, mannose 등으로 구성되었고, 아미노산은 glycine, leucine, alanine 이외 기타 아미노산으로 구성되어 있다. 담도결찰 쥐에서 G009투여군은 대조군에 비하여 간섬유화 유발물질로 추정되는 혈중 Procolagen type III peptide의 감소시켰고 간조직중 총 collagen의 양도 감소시켰다. 또한 조직학적 검사 결과로도 간섬유화의 억제가 뚜렷하였다. 각종 간손상 유발물질에 대하여도 G009투여군은 대조군에 대하여 정상군과 동일한 수준으로 GOT, GPT, triglyceride수치를 보였으며 간조직도 정상군에 가까운 결과를 보였다.

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Esophagoaortic Fistula Caused by Esophageal Tuberculosis-A Case Report- (식도 결핵에 의한 식도 대동맥류-1례보고-)

  • 이희성;이원진;최광민;안현성;홍기우
    • Journal of Chest Surgery
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    • v.34 no.3
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    • pp.256-259
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    • 2001
  • 식도 결핵은 아주 드문 질환으로 연하곤란과 흉통이 가장 흔한 증상이면 다량의 토형은 드문 것으로 되어 있다. 본원에서는 다량의 토형을 동반한 식도 결핵에 의한 식도 대동맥루를 가진 환자를 지험했다. 4세 남자 환자는 다량의 토혈로 응습실을 통해 입원했다. 내원 당시 응급으로 시행한 내시경 검사상 incisor로부터 25cm 하방에 0.7 cm의 풍부한 혈관성의 육아종성 병변을 발견하고, 응급개흉술로 식도의 종양성 병변에 대해 쐐기 절제술을 시행하였다. 식도의 종양성 병변부위는 대동맥과 심게 유착되어 있었고 식도에서 대동맥쪽으로의 식도루를 이중 결찰했다. 환자는 술후 8일째 갑작스런 흉관을 통한 다량의 출혈과 구토 후 토형이 있어 응급 재 개흉술을 시행하여 대동맥파열과 식도 문합부 파열을 확인하였으나 더 이상의 교정이 불가능하여 사망하였다. 이에 문헌고찰과 함께 보고하는 바이다.

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Radiographic and biochemical changes in dogs with experimental portal vein branch ligation (실험적 간문맥 분지 결찰 개에서 방사선학적 및 혈청화학적 변화)

  • Lee, Young-won;Yoon, Jung-hee
    • Korean Journal of Veterinary Research
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    • v.38 no.3
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    • pp.674-678
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    • 1998
  • Radiograph and serum activities were investigated in six dogs with experimental portal vein branch ligation. Operative mesenteric portography showed the incomplete portal vein circulation due to ligation of portal vein branch. Several serum enzyme activities were measured after portal vein branch ligation. Albumin and total protein were decreased following the time. Others were increased. In microscopic findings, hepatocellular necrosis and haemorrhage were identified in midzone and centrilobular zone. And reverse lobulation pattern was found in dogs with portal vein branch ligation.

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A Giant Bronchial Artery Aneurysm in Brochiectatic Patient -One case report- (기관지 확장증 환자에서의 거대 기관지 동맥류 -1예 보고-)

  • 최세용;안창;민선경;한재진;안재호;원태희
    • Journal of Chest Surgery
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    • v.37 no.11
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    • pp.951-954
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    • 2004
  • Bronchial artery aneurysm is a rare but life-threatening disease when it ruptures, and it requires prompt treatment to prevent from catastrophic ruptures. A 78-year-old woman was referred to our hospital to evaluate mediastinal massfound on chest computed tomography. We did a selective bronchial artery angiography and diagnosed as bronchial artery aneurysm. Aneurysmectomy with division of afferent and efferent arteries was performed through standard thoracotomy without cardiopulmonary bypass. The patient recovered uneventfully and was discharged on postoperative 8th day without any complications.