• 대한추나의학회지
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• 제5권1호
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• pp.109-116
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• 2004

Objective : There is no case report on the Idiopathic Conjunctive treated by CHUNA manual therapy in oriental medicine. We experienced a patient with the Idiopathic Conhunctivitis improved by CHUNA manual therapy in X-ray imagine and visual analogue scale(VAS), and we report It. Methods : During the patient with the Idiopathic Conjunctivitis was treated CHUNA manual therapy, we examined cervial X-ray and evaluated the patient's symptoms by VAS and counting eye drop. And we observed whether the change exist or not in X-ray. Result : Symptoms(Red eye, eye xerosis) was improved significally, and the X -ray image was improved. Conclusion : Conjunctivitis was generally treated steroid eye drop and conservative treatment. But CHUNA manual therapy may be more effective in the Idiopathic Conjunctivitis, if more clinical studies and researchs are accomplished.

• Clinical and Experimental Pediatrics
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• 제45권8호
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• pp.1048-1051
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• 2002

저자들은 8세 남아에서 고열, 저혈압, 부정형 피부 발진, 의식저하, 결막염, 구토, 설사, 핍뇨, 혈소판 저하, 혈액배양 음성과 같은 독성 쇼크 증후군의 증상과 함께 관상동맥류를 포함한 가와사끼병의 임상증상을 보인, 독성 쇼크 증후군 증상으로 나타난 비전형적 가와 사끼병 1례를 경험하였기에 문헌고찰과 함께 보고하며, 독성 쇼크 증후군의 치료 중 발열이 지속될 때 가와사끼병의 비전형적인 증상 발현일 수 있음을 염두해야 할 것으로 사료된다.

• Clinical and Experimental Pediatrics
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• 제46권11호
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• pp.1135-1138
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• 2003

저자들은 어린선과 과각화증의 특징적인 피부 소견과 결막염, 청력 소실로 KID 증후군이 진단된 환자에서 심한 성장 장애와 담즙 정체, 단백뇨가 동반된 1례를 경험하였기에 이를 보고하는 바이다.

• 한국임상수의학회지
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• 제23권2호
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• pp.153-157
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• 2006

The purpose of this study was to determine the effects of mitomycin C on conjunctival fibroblast proliferation and apoptosis. Rabbit conjunctival fibroblast mono layers were treated with 48 hours application of mitomycin-C. The viability of cells was evauated by MTT assay. To examine the effect of mitomycin-C on the cell proliferation, immunocytochemistry for BrdU staning was performed. Then, we investigated whether mitomycin-C induced cell's apoptosis by TUNEL staining. As a result of MTT assay, the viability of cells was gradually inhibited in a dose dependent manner by mitomycin-C. The BrdU staining showed that mitomycin-C significantly suppressed the proliferation of conjunctival fibroblast at concentrations of 0.02% or more. When TUNEL assays were performed, the number of apoptotic cells increased 5.6-, 18.5-, and 33.8-fold compared with the control at 0.01, 0.02, and 0.04%, respectively, of mitomycin-C at 48 hours of exposure. Therefore, mitomycin-C may be useful as a regulator in the treatment of corneal diseases that manifest with scar formation and tumor of fibroblast expansion.

• Archives of Plastic Surgery
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• 제36권2호
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• pp.194-199
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• 2009

Purpose: The orbital fat buldging may cause irregular contour of lower eyelid, which is not youthful appearance. The conventional method of fat excision may cause the eyeball to move backward and downward, making enopthalmia is inevitable. The transcutaneous approach to reach the orbital septum can increase the risks of scleral show resulting from scarification at the level of the septum orbicularis junction and damaging the vertical motor branches of the preseptal orbicularis oculi muscle of the lower eyelid. Method: From July 2007 to March 2008, total of 21 patients underwent transconjunctival capsulopapebral fascia fixation procedure. In 8 patients, the herniated fat pad of the lower eyelid was relocated back into the orbit without external skin excision using capsulopalpebral fascia fixation. But in 13 patients, excision of redundant skin of the lower eyelid was performed using pinching technique, not involving orbicularis oculi muslce. In 5 patients, lateral canthotomy was done bilaterally for good visual field. In 6 patients, lateral canthopexy was also combined to correct loosening of lower eyelid. Results: Most of the patients were satisfied after at least 5 months of follow up. No patient showed scleral show. But 2 patients complained of undercorrection slightly, without secondary operation in 1 patient and re - capsulopalpebral fascia fixtation through transconjunctival approach in another patient. Conclusion: Orbital fat repositioning using transconjunctival capsulopalpebral fascia fixation is a good procedure to show youthful appearance without increasing the risk of scleral show and also showed fast recovery compared to the conventional transcutaneous approach.

• 약학회지
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• 제55권1호
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• pp.22-31
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• 2011

This systematic review was conducted to assess the clinical effect of ocular fluoroquinolones used for the treatment of bacterial conjunctivitis. A literature search for randomized controlled clinical trials registered up to January 2010 based on PubMed database, using the following search terms: conjunctivitis and fluoroquinolones (besifloxacin, moxifloxacin, gatifloxacin, levofloxacin, lomefloxacin, ciprofloxacin and ofloxacin) were performed. Pooled data on the clinical resolution and bacterial eradication rates derived from selected 16 studies were reported as the relative risk (RR) and 95% confidence interval (95% CI) compared with placebo. Early clinical resolution and microbiological eradication rates in placebo were 28% and 62% respectively. Fluoroquinolones were significantly effective comparing to placebo: early RR 1.94 (95% CI 1.60~2.34) and late RR 1.30 (1.19~1.43) in clinical resolution rates, and early RR 1.75 (1.58~1.94) and late RR 1.28 (1.18~1.39) in microbiological eradication rates. Besifloxacin, ciprofloaxain and moxifloxacin in clinical resolution, and besifloxacin and levofloxacin in microbiological eradication showed higher RRs than pooled overall fluoroquinolones' RRs. New quinolones had higher antibacterial potencies for all pathogens isolated from bacterial conjunctivitis and resistant isolates than old generation quinolones. In conclusion, ocular 7 fluoroquinolones were all effective than placebo for bacterial conjunctivitis and there were differences between quinolones in early and late clinical resolutions and microbiological eradications, and no differences in safety comparing to placebo.

• 경영과학
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• 제30권1호
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• pp.91-102
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• 2013

This study has an aim to analyze the effects of ADS on conjunctivitis patients among the residents of Seoul, Korea, between 2005 and 2008. For this purpose, the number of medical services provided to conjunctivitis patients on the days of windblown dust storms and the days without any windblown dust storms were analyzed by conducting paired t-test. The interactive effects of the ADS density and the accuracy of ADS forecast on the fluctuation of conjunctivitis cases were also investigated. The results showed that, even with an accurate forecast issued 24 hours prior to the event, the average number of medical services provided for conjunctivitis was higher on the index days than the comparison days. On the other hand, in cases of failure to provide an accurate forecast 24 hours prior to the ADS event, the number of conjunctivitis attacks reported was statistically significantly higher on the index days for 3~5 days after the occurrence of a dust storm in relation to the comparison days. We also found that the rate of increase in asthma treatments on the index days with low level of $PM_{10}$ concentration rather than high $PM_{10}$ level was more significant for all lag days. This study provides evidence that ADS events are significantly associated with conjunctivitis symptoms and the failure to forecast ADS events with low $PM_{10}$ level might aggravate conjunctivitis disease.

• Archives of Plastic Surgery
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• 제38권4호
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• pp.543-546
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• 2011

Purpose: LASIK, one of the currently popular ophthalmic procedures, can sometimes result in dry eye symptoms. In the patient who had underwent LASIK operation, the periorbital surgery may be more likely to lead to such a complication as dry eye symptom. We would like to report a case of corneal abrasion occurred after transconjunctival blepharoplasty in post-LASIK state and suggest the method about preventing the complication. Methods: A 30-year-old female patient underwent transconjunctival blepharoplasty and microfat graft into the face. She had history of LASIK operation 2 years ago. Corneal protector was applied to both eye during transconjunctival operation. After the surgery, she complained of visual blurring at left side. Ophthalmic examination revealed corneal abrasion of left eye. Results: Cornea protecting lens was applied to left eye for 2 weeks. Steroid and antibiotic eye drops were applied for relieving the symptoms and the prevention from progressing of complication. After 1 week, visual power and acuity was recovered to preoperative state. No other specific complications happened. Conclusion: Post-LASIK patient may have possibility of decreased corneal sensation and tear production. Preoperative ophthalmic examination is recommended for the prevention of complication. When corneal protector is applied, we suggest Optagel$^{(R)}$ as a useful lubricant.

• Radiation Oncology Journal
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• 제20권2호
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• pp.139-146
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• 2002

목적 : 원발성 안와 림프종로 진단 받고 방사선치료를 받은 환자들을 대상으로 치료 반응, 재발 양상, 생존률 및 치료 부작용에 대해 알아보고자 하였다. 대상 및 방법 : 1991년 2월부터 2001년 4월까지 서울중앙병원에서 원발성 안와 림프종으로 진단 받고 방사선치료를 받은 31명의 환자를 대상으로 후향적 분석을 시행하였다. 성별분포는 남자가 18명, 여자가 13명이었다. 연령은 3세에서 73세까지 분포하였으며 중앙값은 44세였다. 원발 부위는 결막이 9명, 안검이 12명, 안와가 10명이었다. 병리학적 소견은 MALT (low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type) 림프종이 28명, diffuse large B-cell 림프종이 1명, anaplastic large cell 림프종이 1명이었으며 lymphoblastic 림프종이 1명이었다. Ann Arbor staging에 따른 병기 분포를 살펴보면 1기가 31명으로 전부를 차지하였으며 각각 비장, 신장, 골수와 맥락얼기(choroid plexus)에 병변이 있었던 환자 4명은 연구에서 제외하였다. 전체 환자 중, 양측 안와 침범이 있는 환자는 6명이었다. 방사선치료는 결막과 안검 부위는 $6\~16\;MeV$의 전자선을 이용하여 전방 1문 치료로 30 Gy/10 fractions을 조사하였고, 안와 부위는 4 MV, 6 MV의 광자선을 이용하여 쐐기를 이용한 전사방 2문 치료로 $20\~28$회에 걸쳐 총 $40\~50.4\;Gy$를 조사하였다. 특히 결막과 안검 부위는 수정체를 보호하기 위한 납차폐물이 사용되었다. 항암화학요법은 12명의 환자에서 시행되었다. 중앙 추적 관찰기간은 53개월이었다. 결과 : 전체 환자의 5년 생존율은 $90.7\%$이었으며, 2명이 질병과 무관하게 폐렴과 비소세포성 폐암으로 사망하여 질병관련(cause-specific) 5년 생존율은 $96.0\%$이었으며 5년 무병 생존율은 $80.0\%$, 5년 국소제어율은 $90.5\%$였다. 방사선치료를 받은 31명 모두가 치료 후 6개월 이내에 완전관해를 보여 완전관해율은 $100\%$였다. 이 중 국소 재발은 방사선치료 후 16개월과 18개월에 2명의 환자에서 보였고 구제 방사선치료 후 모두 완전관해를 보였다. 2명이 조사 영역 밖에서 재발하였고 lymphoblastic 림프종 환자가 방사선치료 후 18개월에 골수에서 재발하여 사망하였고 MALT 림프종 환자가 방사선치료 후 41개월에 폐에 재발하여 구제 방사선치료 후 완전관해를 보였다. 12명의 환자가 방사선치료 전에 항암화학요법을 받았으며 부분관해가 11명에서 나타났고 1명은 반응을 보이지 않았다. 방사선치료 당시 시력이 있었던 29명 중 5명에서 방사선유발 백내장이 발생하였으며 2명에서 안구건조증이 발생하였다. 결론 : 원발성 안와 림프종의 대부분이 MALT 림프종이었다. 방사선치료는 매우 좋은 치료 반응과 국소 제어율을 보였으며 높은 생존율을 보였다. 국소 재발한 경우에도 방사선치료가 구제치료의 역할을 할 수 있음을 알 수 있었으며 대부분의 환자에서 심각한 후유증을 보이지 않는 안전한 치료로 생각된다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제16권1호
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• pp.99-103
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• 1994

협골체 골절시 접근방법은 안와하연에 대해 섬모하절개, 하안검절개, 안와하연절개 및 결막절개등이 사용되고 안와측벽, frontozygomatic suture에 대해서는 lateral brow incision, 상안검절개등이 사용되며 관상절개술은 frontozygomatic suture와 협골궁에 접근할 수 있다. 관상절개술을 제외한 접근방법은 한가지 절개술로 단지 한부위의 정복과 고정술이 가능하므로 결국 협골체 골절시 2점이상 고정을 할 경우 2가지 이상의 절개가 필요하게 된다. 이에 저자들은 관상절개술의 적응증이 아닌 협골체 골절에 lateral-canthotomy-conjunctival incision을 사용하여 안와하연 및 측벽의 골절부에 대한 정복술과 고정술을 시행하여 양호한 결과를 관찰하여 이에 보고하는 바이다.