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The Effect of Hemolysis sample on the Result of Nuclear Medicine Blood test (용혈검체가 핵의학 검체검사 결과에 미치는 영향)

  • Kim, Jin-Tae;Lee, Jong-Pil;Lee, Soo-Bin;Kim, Dong-Min
    • The Korean Journal of Nuclear Medicine Technology
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    • v.25 no.1
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    • pp.41-43
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    • 2021
  • Purpose In nuclear medicine blood tests, hemolysis samples are considered as inappropriate sample and are recommended not to be used for blood test. So, the lab are required to collect the blood again in the blood collection room However, The effect of hemolyzed samples on radioimmunoassay has not studied yet. This study was designed to evaluate effects of hemolysis on radioimmunoassay. Materials and Methods The kit manuals of 23 test items were reviewed to confirm whether hemolyzed samples were used. The subjects were 19 general applicants(male : 9, female : 13) and the samples were collected by each two SST tubes, one tube was obtained by centrifugation normally, and the other was obtained hemolyzed sample by centrifugation after external shock. It has been known that highly hemolyzed samples can affect the test results, so the test was performed using the severe hemolyzed sample. The test was performed for each test item using 23 normal serum and hemolysis serum, and SPSS19 program was used for statistical comparison of the test result. Results There was no significant difference between normal serum and hemolysis serum in 21 of 23 test items, but the results of insulin and C-peptide were significantly different(P<0.05). Conclusion It has been known that hemolysis in blood samples can affect the results of biochemical and hematological test, However, hemolysis effect is relatively low. Similarly, this study showed that hemolysis had not much effect on most of immunological radioimmunoassay except for some tests. Therefore, it is thought that the demand for re-collection due to hemolysis will be reduced in the laboratory, which will improve the work process of the laboratory.

Designing a Molecular Diagnostic Laboratory for Testing Highly Pathogenic Viruses (고병원성 바이러스 검사를 위한 분자진단검사실 구축)

  • Jung, Tae Won;Jung, Jaeyoung;Kim, Sunghyun;Kim, Young-Kwon
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.2
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    • pp.143-150
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    • 2021
  • The recent spread of novel and highly variant pathogenic viruses, including the coronavirus (SARS-CoV-2), has increased the demand for diagnostic testing for rapid confirmation. This has resulted in investigating the functional capability of each space, and preparing facility guidelines to secure the safety of medical technologists. During viral evaluations, there is a requirement of negative pressure facilities along with thread separation, during pre-treatment of samples and before nucleic acid amplification. Space composition therefore needs to be planned by considering unidirectional air flow. This classification of safety management facilities is designated as biosafety level 2, and personal protective equipment is placed accordingly. In case of handling dangerous materials, they need to be carried out of the biosafety cabinet, and sterilizers are required for suitable disposal of infectious agents. A common feature of domestic laboratories is maintenance of the sample pre-treatment space at a negative pressure of -2.5 Pa or less, and arranging separate pre-treatment and reagent preparation spaces during the test process. We believe that the data generated in this study is meaningful, and offers an efficient direction and detailed flow for separation of the inspection process and space functions. Moreover, this study introduces construction of the laboratory by applying the safety management standards.

A Case of Recurred Pseudomyxoma Peritonei Identified by Serially Elevated Serum CEA Levels after Cytoreductive Surgery and Intraperitoneal Chemotherapy (수술과 항암치료 후 종양표지자 검사의 상승으로 복막 가성점액종의 재발을 확인한 1례)

  • In Sub Han;Geun Am Song;Kwang Ha Kim;Bong Eun Lee;Dong Hoon Baek;Seong Jun Lee;Moon Won Lee;Sung Yong Han
    • Journal of Digestive Cancer Research
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    • v.4 no.1
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    • pp.32-35
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    • 2016
  • Pseudomyxoma peritonei (PMP) is a rare clinical syndrome characterized by profuse jelatinous materials in the abdominal cavity and pelvis with mucinous implants on the peritoneal surface. There are some studies for serum tumor markers, including carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9) and carbohydrate antigen 125 (CA125), to assess the risk of recurrence following cytoreductive surgery and intraperitoneal chemotherapy. However, rare cases were reported about recurrence with increasing serum CEA levels. Herein, we report a case of recurrence of PMP according to serially elevated serum CEA.

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Papillary Fibroelastoma of the Aortic Valve: Discovered by Chance with Intraoperative Transesophageal Echocardiography - A case report - (수술실 내 경식도 심장초음파검사에서 우연히 발견된 유두상 섬유탄력종 - 1예 보고 -)

  • Kim, Jeong-Won;Jung, Jong-Pil;Park, Soon-Eun;Kim, Young-Min;Park, Chang-Ryul;Shin, Je-Kyoun
    • Journal of Chest Surgery
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    • v.40 no.9
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    • pp.637-640
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    • 2007
  • Papillary fibroelastoma is a rare benign cardiac tumor with an elevated risk for embolization and most papillary fibroelastomas do not cause symptoms. In this report, we describe a case of previous undiagnosed masses of the aortic valve that were incidentally found on intraoperative transesophageal echocardiography during coronary artery bypass surgery. Upon surgery, masses were found on the left and right aortic cusps and the pathological findings were consistent with a papillary fibroelastoma.

Introduction to research on experiments in real sea areas of autonomous Ship (자율운항 선박 실해역 실험 연구 소개)

  • Jin-Soo Kim;Nam-Kyun Im;Donggyun Kim;SungJoon Kim
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2023.05a
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    • pp.258-260
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    • 2023
  • 목포해양대학교와 삼성중공업은 2021년 공동 연구를 통하여 '실습선 기반 원격/자율 운항 선박 시스템 개발 및 검증'을 수행하였고 이를 통하여 목포해양대학교 실습선인 세계로호를 활용하여 삼성중공업의 자율운항 선박 시스템(Autonomous Navigation System)인 SAS의 Test Bed 시연 실험 시스템을 구축하여 2022년 자율운항 선박(MASS) 기술 요소에 대한 시뮬레이션 기반 SAS(Samsung Autonomous Ship) System 검증 및 '운항 노선에 대한 설정을 통한 선박 자율운항 검증'을 위한 실선·실해역 실험을 통해 이를 시연 및 검증을 시행하였다. 특히 의미 있는 것은 자율운항선박 실선 테스트 과정 중 발생할 수 있는 모든 위험요소 분석을 위해 한국선급과 HAZID Workship을 실시하였고, 이를 통해 국내최초 자율운항실험용 기국 승인 및 선급임시검사 완료 후 실험이 진행되었다는 것이다. 이 연구에서는 실습선 기반 자율운항 선박 실해역 실험 연구를 소개하고 그 결과를 운항자 입장에서 분석하여 향후 보완하여야 할 사항을 제시하였다.

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A Study on the Relationships among Students' Perceptions of Computerized Science Learning Environments, Computer-Related Attitudes, and Computer Experiences (컴퓨터실 과학 학습 환경에 대한 인식과 컴퓨터 관련 태도 및 컴퓨터 경험의 관계성 조사)

  • Noh, Tae-Hee;Cha, Jeong-Ho
    • Journal of The Korean Association For Science Education
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    • v.20 no.1
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    • pp.12-19
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    • 2000
  • The relationships among students' perceptions of computerized science learning environments, computer-related attitudes. and computer experiences were investigated with a sample of 164 9thgraders (80 boys and 84 girls) from two middle schools. The Computerized Science Learning Environment Inventory (CSLEI) and the Computer-Related Attitudes Scale (CRAS) were administered, and students' computer experiences were examined. Students' perceptions of preferred learning environments were also studied with the preferred form of the CSLEI, and compared with those of actual learning environments. Gender differences in the perceptions of computerized science learning environments, computer-related attitudes, and computer experiences were also studied. Students' perceptions of preferred learning environments were significantly better than those of actual learning environments in all subscales of the CSLEI except gender equity. There was no gender difference in the perceptions of computerized science learning environments. However, boys were found to have more positive computer-related attitudes and more computer experiences than girls. Students' perceptions of computerized science learning environments were significantly correlated with computer-related attitudes in resource adequacy subscale, but not with computer experiences. Significant relationships between computer-related attitudes and computer experiences were also found.

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First Report on External Quality Assurance Study of Radioassay of Thyroid Related Hormones - First One Year of Operation From 1989. 9 To 1990. 8- (갑상선 호르몬의 외부정도 관리 분석 -1989년 9월부터 1990년 8월까지 첫해 시행 결과-)

  • Lee, Dong-Soo;Cho, Bo-Youn;Kwark, Cheol-Eun;Seo, Il-Taek;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.25 no.2
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    • pp.266-279
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    • 1991
  • 1989년 9월부터 1990년 8월까지 국제 원자력기구의 지역 계획에 의해 국내 26개 (후반부 31개)의 기관이 참가하여 T3, T4, TSH를 측정하여 결과를 모으고, 외부정도관적를 시행한 결과가 다음과 같다. 1) 외부정도관리를 위한 컴퓨터 소프트웨어를 작성하였다. 데이타의 입력, 정도 분석, 월별 보고, 분기별 보고 및 수행 분석 프로그램을 만들되 전체 검사실결과에서 추린 평균값(all laboratories trimmed mean: ALTM)으로 모집단평균을 삼아 편차, 편이, 편이평균 그리고 이들의 경시적 변화를 분석하도록 하였다. 2) 전후반 2회에 나누어 만든 및치 사이의 편차는 유의하지 않았다. T3값의 변이계수는 7.2%이하(정상 T3 값) 또는 9.2%와 13.4%사이 (높은 T3 값), 74 값의 변이계수는 4.6%이하(정상 또는 높은 T4값), 5.4%와 9.5%사이(낮은 T4값)이었다. TSH는 정상범위 값에서 21.7%이하의 변이 계수를 보였고 정상보다 낮거나 높은 TSH의 풀은 8 7%와 21.2%사이의 변이제수를 보였다. 3) 전체 검사실 추린 평균값(ALTM)에 따른 변이계수의 변동은, ALTM이 정상 T4값범위일 때 변이계수는 15%이하이었고, 낮은 T4값일 때는 중간값이 15%이고 분포범위는 50%까지이었다. T3값의 변이계수는 대체로 20%이하이었다. TSH의 변이계수는 1mU/L를 전후로 급격히 상승하여 200%에 달하였다. 4) 3표준편차보다 높거나 낮은 값을 보인 검사실들의 분포는 전체 검사실결과에서 추린 평균값(ALTM)과 상관없었다. 5) 첨가한 T3, T4, TSH에 대한 회수율은 T4는 104, 106%, T3는 67%, 74%, TSH는 87%, 86%이었다. 이상과 같이, 저자들이 만든 소프트웨어 프로그램으로 외부정도관리를 위하여 쉽게 데이터를 분석하고 보고서를 작성하여 갑상선호르몬의 경사신뢰도를 평가할 수 있게 되었으며, 위에 요약한 첫 해의 외부정도관리 결과를 바탕으로 참가기관의 동의하에, 앞으로 정도관리 항목의 확대와 외부정도관리의 지속적인 시행이 바람직하다고 생각하였다.

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Report on the improvement of the in vitro and specimen reception environment system (핵의학과 검체 접수 환경시스템의 개선사례 보고)

  • Kim, Jung In;Kang, Mi Ji;Kim, Na Kyung;Park, Ji Sol;Kwon, Won Hyun;Lee, Kyung Jae
    • The Korean Journal of Nuclear Medicine Technology
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    • v.25 no.2
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    • pp.29-34
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    • 2021
  • Purpose Sample reception environment system in nuclear medicine has not changed much compared to 20 years ago. When preparing sample for in vitro test, there was no significant change because the test was carried out by generating an own specimen from the parent specimen. In this study, We would like to introduce a method that automatically removes the sample cap using the automated decapper equipment and enables automatic reception at the same time. In addition, including a provisional reception system. Materials and Methods In 2019, it was intended to get a device that automatically removes the cap of a patient's blood sample. This equipment is the same as the equipment used in the Department of Laboratory Medicine (Vacuette Ⓡ Unicap Belt Decapper, Greiner bio-one, Austria). However, the purchase was delayed due to differences in tube size, budget, and space. In January 2020, we borrowed domestic automatic decapper equipment and modified it to suit our laboratory environment. After 9 months, we were able to introduce a system that automatically removes the lid of a patient's blood sample and at the same time automatically accepts the test. And, through the provisional reception system, it was possible to know the arrival of the specimen in a short time. Results With the use of an automatic decapper device, the sample cap was automatically removed, and the reception proceeded at the same time. So, it was very efficient at work because it shortened the sample preparation time by about 20 minutes. In addition, it was possible to prevent the examiner's musculoskeletal disorders caused by repeated wrist use. After using the provisional reception system, patients were able to be discharged quickly, and the number of phone calls to confirm the arrival of samples was reduced. Conclusion Most hospitals have about four employees in the nuclear medicine in vitro laboratory. It is effective to use automatic decapper equipment and a provisional reception system for organizations that perform work with the minimum number of personnel.

수혈로 인한 에이즈감염, 위험성 있다

  • 이주실
    • RED RIBBON
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    • s.53
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    • pp.16-17
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    • 2003
  • 얼마전 수혈로 인한 에이즈감염보도 이후 헌혈 혈액에 대한 의심이 커지고 있다. 현재 국내에서는 헌혈 혈액에 대해 어떠한 검사를 실시하고 있으며 왜 에이즈에 감염된 혈액이 수혈자에게 공급하게 되었는지 살펴보자.

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