• Korean Journal of Plant Resources
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• v.20 no.5
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• pp.375-382
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• 2007

The vascular plants of the studied area in the Mt. Seokbul appeared to be 342 taxa; 96 families, 249 genera, 293 species, 2 subspecies, 43 varieties and 3 forms and 1 cultivar. Based on the list of the rare plants by the Forest Research Institute, 2 taxa existed in the studied areas; Lloydia triflora(Preservation priority order; No. 169), Aristolochia contorta(No. 151) and based on the list of Korean endemic plants, 7 taxa existed; Cephalotaxus koreana, Carex okamotoi, Populus tomentiglandulosa(Planted species), Indigofera koreana, Weigela subsessilis. Rhododendron yedoense var. poukhanense, Forsythia koreana (Planted species). Specific plant species by floral region were total 18 taxa; Wistaria floribunda(Planted species) in class IV, Lloydia triflora, Acer palmatum in class III, 15 taxa (Cephalotaxus koreana, Quercus variabilis, Ulmus parvifolia, Aristolochia contorta, Pyrus ussuriensis, etc.) in class I. The naturalized plants in this site were 11 families, 26 genera, 32 species, 2 varieties, 34 taxa, and naturalization rate was 9.9% of all 342 taxa vascular plants. The plant communities in the Mt. Seokbul were classified as; Pinus densiflora community(No. 1, 3, 4) and Pinus thunbergii community(No.2).

• KSBB Journal
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• v.15 no.5
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• pp.434-437
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• 2000

The contents and composition of alkaloids homoharringtonine, harringtonine, and cephalotaxine were determined in Korean native plumyew tree (Cephalotaxus koreana) collected from 17 different sites in Korea. The alkaloid contents of C. koreana varied with locations and plant populations from 11.8 mg/g to 195.2 mg/g of dry weight while C. koreana in southern area had higher alkaloid contents. The alkaloid compositions in C. koreana were highest with homoharringtonine (40%) and followed harringtonine (32%) and cephalotaxine (28%). Total alkaloids and homoharringtonine contents in needles were higher than those of stem by 2 fold. Alkaloid contents of C. koreana were the highest in winter, and the lowest in summer. Comparison of alkaloid contents and composition with other species of Cephalotaxus revealed that C. koreana was different to C. harringtonia, and contents of homoharringtonine were higher than other species. C. koreana could be potential source for homoharringtonine and related alkaloids.

• Korean Journal of Environment and Ecology
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• v.16 no.3
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• pp.296-308
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• 2002

The vascular plants in Mt. Cheongwan, Jangheung-gun, Jeollanam-do, were consisted of 599 taxa; 117 families, 366 genus, 519 species, 76 varieties and 4 forma. From the floristic point of view, Mt. Cheongwan is distributed to both the evergreen trees as Pteris mulfida, Dryopteris bissetiana, Torreya nucifera, Cephlotaxus koreana, Neolitsea sericea, Quercus acuta, Hedera rhombea, Fatsia japonica, Camellia japonica, Eurya japonica, Thea sinensis, Acorus gramineus, Pseudosasa japonica and Sasa borealis, and the deciduous subtropical trees such as Carpinus coreana, Aphanth aspera, Orixa japonica, and Lygodium japonicum And it is worth special mention to be discovered Selaginella rossii, Corylopsis coreana, Stewartia koreana, Asarum sieboldii, Viola orientals, and Drosera royundifolia. The Specific plants which is categorized to the Degree by the Ministry of Environment recorded as 45 taxa; 1 species each for the Degree II, IV and V, 5 species for the Degree III, and 37 species for the Degree I.

• Journal of Korean Society of Forest Science
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• v.98 no.4
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• pp.491-495
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• 2009

This study was conducted to investigate the propagation characteristics of Cephalotaxus koreana by cutting, whose plant has been known to new anticancer treatments. The treatments of plant growth regulators, cutting media temperature and growing media were investigated to know the rooting ability of cuttings. For rooting formation affected by plant growth regulators and its concentration, The application of IBA 100 mg/L was most effective in all of the characteristics including rooting rate of 88.5%. The optimum media temperature by cutting was $24^{\circ}C$ (treatment IBA 100 mg/L, rooting rate 84.6%), predicting that greenwood cutting from June to July is most effective. VPPL (vermiculite+peatmoss+perlite 1:1:1(v/v/v)) showed the highest value in all of the characteristics including rooting rate of 68.5% for the effect of growing media on rooting formation.

• Korean Journal of Plant Resources
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• v.21 no.2
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• pp.117-127
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• 2008

The vascular plants in the Eco-Arboretum site, Mt. Gumwon appeared to be 369 taxa; 84 families, 217 genera, 319 species, 43 varieties and 7 forms. Based on the list of the rare plants, 2 taxa existed in the studied areas; Abies koreana (Preservation priority order; No. 73), Paeonia obovata (No. 97) and based on the list of Korean endemic plants, 12 families, 14 genera, 11 species, 3 varieties, 1 hybrid, 15 taxa existed; Cephalotaxus koreana, Abies koreana (Planted species), Carex okamotoi, Salix hallaisanensis, Salix purpurea var. japonica, Clematis trichotoma, Thalictrum actaefolium, Lespedeza ${\times}$ tomentella, Vicia nipponica, Stewartia koreana, Hypericum attenuatum var. confertissimum, Paulownia coreana (Planted species), Weigela subsessilis, Aster koraiensis (Planted species). Specific plant species by floral region were total 38 taxa; Paeonia obovata in class V , 13 taxa (Lilium leichtlinii var. tigrinum, Betula costata, Betula davurica, Ulmus davidiana, Spiraea frutschiana, Prunus maackii, Syringa reticulata var. mandshurica, Cynanchum inamoenum, Lonicera subhispida, Cacalia firma, etc.) in class III , 5 taxa (Heloniopsis orientalis, Chrysosplenium pilosum, Acer triflorm, Viola tokubuchiana var. takedana, Teucrium veronicoides, etc.) in Class II . 19 taxa (Dryopteris erythrosora, Arisaema ringens, Veratrum versicolor, Polygonatum inflatum, Salix glandulosa, Betula schmidtii, Alnus hirsuta, Quercus variabilis, Aconitum japuense, Dicentra spectabilis, Chrysosplenium flagelliferum, Impatiens noli-tangere, Ilex macropoda, Tilia amurensis, Fraxinus mandshurica, Trigonotis icumae, etc.)in class I . The naturalized plants in this site were 5 families, 13 genera, 15 taxa (Rumex acetocella, Rumex obtusifolius, Trifolium repens, Oenothera odorata, Erigeron annuus, Erigeron philadelphicus, Bidens frondosa, Taraxacum officinale, etc.) and naturalization rate was 4.1% of all 369 taxa vascular plants.

• Korean Journal of Environment and Ecology
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• v.16 no.4
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• pp.359-386
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• 2003

The vascular plants in Baekdudaegan of the South Korea were recorded of 1,477 taxa; 126 families, 641 genus, 1,248 species, 3 subspecies, 204 varieties, 22 forma. From the floristic point of view, Jirisan, Backunsan and Duckyusan District in the Baekdudaegan belongs to the southern province in Korea, appeared to Cephalotaxus koreana, Lindera obtusiloba, Lindera erythrocarpa, Lindera glauca, Izex macropoda, Meliosma myriantha, Melisoma oldhami and Stewartia koreana. But on the top regions of these mountains more than 1,000m above the sea level were contained many alpine plants. And on the top regions and ridgeline parts of Duckyusan and Jirisan were the middle province, owing to Betula costata, Betula ermani, Ulmus laciniata, Isopyrum raddeanum, Hylomecon vemale, Viola diamantica, Vaccinium koreanum, Heloniopsis orientalis, Disporum ovale, Symplocarpus renifolius and Veronica arvensis. These results were epresented that plant species of the middle province moved to the South along the ridgeline of Baekdudaegan, on the other hand plants of southern province had biological niche of low ground according to go toward the North.

• Korean Journal of Plant Resources
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• v.23 no.2
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• pp.172-178
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• 2010

This study was carried out to investigate abiotic and biotic environmental factors affecting homoharringtonine (HHT) contents of Cephalotaxus koreana, whereby, to provide basic information of high value-added industry production of HHT as a promising anti-cancer agent. For correlation between abiotic environmental factors (soil moisture, soil pH, habitat density and temperature) and HHT contents, the contents were highly correlated with soil moisture (0.77) and soil pH (-0.68). For multiple regression analysis of relationship between abiotic environmental factors (soil moisture and soil pH) and HHT contents, soil moisture appeared to be strongly affecting the contents relatively due to being significant at only its regression coefficient ($26.48^{***}$). For the effect of biotic environmental factors (damage index) affecting HHT contents, the contents was quadratic with equation of $H=278.23+1242D-398.87D^2$, also, damage index had strong effect on the contents. Finally, for the result of the most influencing an environmental factor on HHT contents, both damage index and soil moisture were suitable in second polynomial regression, also, damage index ($R^2=0.73^{***}$) was turned out to be more influencing factor than soil moisture ($R^2=0.67^{**}$) on HHT contents relatively. Therefore, we predict that HHT contents in the trees of Cephalotaxus koreana is produced as a chemical defense mechanism triggered by a stress-related damage of fungi or insects.

• Korean Journal of Plant Resources
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• v.13 no.2
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• pp.89-94
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• 2000

Cephalotaxus koreana Nakai is endemic species of Korea. Since old days, the fruits have been used as a parasiticide and leaves have been used for a pierced wound by insects. The essential oil components from its aerial parts and stem bark by steam distillation were investigated. Several compounds were characterized by GC-Mass spectra. It was found that the leaves, stembark and flowers contain the compounds of essential oils, 1-octene-3-ol, hexadecanoic acid; $\alpha$-pinene, $\Delta^3$-carene mainly, linalylacetate, $\beta$-cubebene, 3,4-octadine-7-methyl , ferruginol(stem bark) and $\alpha$-pinene mainly, $\beta$-pinene , cyclopropane-1,1-dimethyl-2-(3-methyl-1,3-butadienyl), etc. This Cephalotaxus spp. contains the first components of ferruginol(M.W.286.03, $C_{20}H_{30}O)$ which belong to diterpene.

• Applied Biological Chemistry
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• v.51 no.2
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• pp.124-128
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• 2008

Cell proliferation inhibitory effects of homoharringtonine (HHT), an active drug substance in Cephalotaxus koreana, against blood cancer cell line K562 were evaluated. In addition, in vivo chronic toxicity test with mouse was carried out. When K562 cell line was treated everyday for 9, 6, 3 days, $IC_{50}$ values of HHT were determined as 0.27, 0.37, and 1.10 mM respectively. The anticancer activity of HHT was comparable to adriamycin, a known anticancer drug compound for blood cancer treatment. in vivo chronic toxicity test of the HHT, the number of red blood cell (RBC) showed no significant difference. From the analysis of the liver-functional enzymes in blood, all of liver damage related enzymes such as glutamate-oxalate-transferase (GOT), glutamate-pyruvate-transferase (GPT), cholesterol (Chol) and alkaline phosphatase (ALP) showed no significant change. However, from the histologic test, a neutrophil of the band type in liver tissue was observed.

• Korean Journal of Plant Resources
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• v.22 no.1
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• pp.26-30
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• 2009

Daucosterol and naphthalene glycoside were isolated from the seeds of Cassia mimosoides var. nomame Makino. The isolated compounds were identified by spectral means including 1D, 2D-NMR and FAB-MS experiments. Daucosterol was characterized as ${\beta}$-sitosterol-3-O-${\beta}$-D-glucoside and naphthalene glucoside was done as 2-acetyl-3-methyl-6-methoxynaphthalene-1,8-diol 8-O-glucosyl-(1${\rightarrow}$6)-glucoside. These compounds were isolated for the first time from Cassia mimosoides var. nomame Makino.