• Title/Summary/Keyword: 개별법

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Improvement of an Simultaneous Determination for Clenbuterol and Ractopamine in Livestock Products using LC-MS/MS (LC-MS/MS를 이용한 축산물 중 clenbuterol과 ractopamine의 동시 분석법 개선)

  • Cho, Yoon-Jae;Chae, Young-Sik;Kim, Jae-Young;Kim, Hyung-Soo;Kang, Ilhyun;Do, Jung-Ah;Oh, Jae-Ho;Kwon, Kisung;Chang, Moon-Ik
    • Korean Journal of Food Science and Technology
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    • v.45 no.1
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    • pp.25-33
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    • 2013
  • Clenbuterol and ractopamine, which are ${\beta}$-agonists, have been misused as a growth promoting agent in meat producing animals. Clenbuterol was banned for veterinary drug in Korea because of its problems regarding safety. Due to their adverse effects, such as cardiovascular and central nervous diseases on human health proper control and monitoring should be conducted. The existing analytical method of clenbuterol and ractopamine in the Food code was improved through our present study. The bovine muscle samples were subjected to enzymatic hydrolysis, extracted with ethyl acetate and defatted by hexane-methanol partitioning. A molecular imprinted polymer (MIP) solid phase extraction cartridge was used for clean-up and LC-MS/MS was operated in positive multiple reaction monitoring (MRM). Clenbuterol-$d_9$ and ractopamine-$d_3$ were used as an internal standard. The renewed method was validated according to the CODEX guideline. The limits of quantitation for clenbuterol and ractopamine were 0.2 and 0.5 ${\mu}g/kg$, respectively. The mean recoveries ranged in 104.2-113.5% for clenbuterol and in 107.6-118.1% for ractopamine. The improved method was able to save both time and expenses.

Fundamentals of Ecotoxicity Evaluation Methods using Domestic Aquatic Organisms in Korea : (I) Fish (국내 생물종을 이용한 생태독성평가 기반연구 : (I) 어류)

  • Nam, Sun-Hwa;Yang, Chang-Yong;An, Youn-Joo;Lee, Jae-Kwan
    • Korean Journal of Ecology and Environment
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    • v.40 no.2
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    • pp.173-183
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    • 2007
  • The Ministry of Environment plans to introduce the Whole Effluent Toxicity (WET) system in Korea. The WET test is well established in developed countries with recognizing of the limitations of physicochemical analysis method and potential risk of chemicals in water medium. Therefore, it is essential to build the ecotoxicity infrastructure for the induction of WET test. In this study, we extensively collected the domestic and foreign toxicity test methods which employ native test species to Korea. And we suggested that the domestic ecotoxicity test methods with domestic test species in Korea through extracting the range of test conditions. Five domestic fish species selected were Carassiu auratus (Crucian carp), Cyprinus carpio(Common carp), Gasterosteus aculeatus (Three spine stickleback), Misgurnus anguillicaudatus (Oriental weather fish) and Oryzias latipes (Japanese medaka), The toxicity test methods with native test species to Korea were collected from the standard methods (OECD, U.S. EPA, ASTM), government reports, SCI papers and domestic papers. We collected the 32 test methods, and suggested the suitable aquatic toxicity test methods for fish. It is expected that this study could prove a useful information to establish the ecotoxicity test methods with domestic aquatic organisms in Korea henceforth.

Multidimensional Scaling Using the Pseudo-Points Based on Partition Method (분할법에 의한 가상점을 활용한 다차원척도법)

  • Shin, Sang Min;Kim, Eun-Seong;Choi, Yong-Seok
    • The Korean Journal of Applied Statistics
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    • v.28 no.6
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    • pp.1171-1180
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    • 2015
  • Multidimensional scaling (MDS) is a graphical technique of multivariate analysis to display dissimilarities among individuals into low-dimensional space. We often have two kinds of MDS which are metric MDS and non-metric MDS. Metric MDS can be applied to quantitative data; however, we need additional information about variables because it only shows relationships among individuals. Gower (1992) proposed a method that can represent variable information using trajectories of the pseudo-points for quantitative variables on the metric MDS space. We will call his method a 'replacement method'. However, the trajectory can not be represented even though metric MDS can be applied to binary data when we apply his method to binary data. Therefore, we propose a method to represent information of binary variables using pseudo-points called a 'partition method'. The proposed method partitions pseudo-points, accounting both the rate of zeroes and ones. Our metric MDS using the proposed partition method can show the relationship between individuals and variables for binary data.

Who Would Amend the Procedural Rules in the Legislature, and Why? An Analysis of Legislators' motivations to Propose Amendments of the National Assembly Law in the 19th Korean National Assembly (누가, 왜 국회법을 개정하려 하는가? 제19대 국회 국회법 개정안 발의 분석)

  • Koo, Bonsang;Park, Wonho
    • Korean Journal of Legislative Studies
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    • v.24 no.2
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    • pp.67-99
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    • 2018
  • This study analyzes the revision bills of the National Assembly Law in the 19th National Assembly in which the National Assembly Advancement Act was enacted, with the question "who are involved in the revision of the procedural rules, and what motivates them?" The cosponsor network analysis focusing on primary sponsors of the revision bills shows that the network was constructed by party affiliations. A small number of members with high degree centrality attempted to cooperate with each other at the cosponsoring stage, but the legislation did not pass through the related committee. In addition, this study tests the four competitive hypotheses (the committee hypothesis, the distributive politics hypothesis, the ideological distance hypothesis, and the partisan affiliation hypothesis) about the motivation to propose amendments by using the regression models which include newly measured variables. Only the committee hypothesis and the partisan affiliation hypothesis are empirically supported. This implies that partisan consideration is still significant in amending the National Assembly Law even after the National Assembly Advancement Act, and thus party leaders' willingness to seek bipartisan compromises is at the heart of problem-solving.

Advaced analysis and optimal design of steel arch bridges (강아치교의 고등해석과 최적설계)

  • Choi, Se Hyu
    • Journal of Korean Society of Steel Construction
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    • v.17 no.1 s.74
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    • pp.13-21
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    • 2005
  • Advanced analysis and optimal design of steel arch bridges is presented. In the design method using an advanced analysis, separate member capacity checks after analysis are not required because the stability and strength of the structural system and its component members can be rigorously treated in the analysis. The geometric nonlinearity is considered by using the stability function. The Column Research Council tangent modulus is used to account for gradual yielding due to residual stresses. A parabolic function is used to represent the transition from elastic to zero stiffness associated with a developing hinge. An optimization technique used is a modified section increment method. The member with the largest unit value evaluated by AASHTO-LRFD interaction equation is replaced one by one with an adjacent larger member selected in the database. The objective function is taken as the weight of the steel arch bridge and the constraint functions account for load-carrying capacities and deflection requirements. Member sizes determined by the proposed method are compared with those given by other approaches.

The Study on motivation factors of G learning through contents analysis (콘텐츠 분석법에 의한 미국 초등학생 G러닝 몰입 요소 분석)

  • Wi, Jong Hyun;Wi, Yokyung
    • Journal of Korea Game Society
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    • v.15 no.6
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    • pp.89-96
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    • 2015
  • The purpose of this paper is to analyze quantitative learning motivation on G learning. For the purpose the paper has analyzed the learning motivation factors through students' review on G learning which had been done at La Ballona Elementary School in Culver City, USA in 2010. On the basis of contents analysis method, it showed what factors of G learning influenced students and raised their academic motivation. Students used the positive, active words such as good, fun, learn, accomplish, easy, quest in terms of learning process, interest and achievement. They also showed future G learning intention describing terms such as love and miss. Team Quest has been especially developed for G learning class this time. Students had to help each other to solve the team quests which is different from traditional textbook. The system raised students' academic motivation.

Apparatus for Comparing Thermal Conductivity of Nanofluids and Base Fluid Using Simultaneously Measured Resistance Variation Signals from Two Hot Wire Sensors (동시에 측정된 두 열선센서의 저항변화 신호를 이용한 나노유체와 기본유체의 열전도율 비교장치)

  • Lee, Shin Pyo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.39 no.1
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    • pp.29-36
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    • 2015
  • Exact comparisons of the thermal conductivities of the base fluid and a nanofluid are very important in the early stages of nanofluid development. A simple procedure of measuring the thermal conductivity of the two fluids by the transient hot wire method and numerically dividing these values is used for this purpose. However, because the experiments are not performed simultaneously and the physical properties of the measurement system are sometimes not properly known, large errors are incurred during the evaluation process. This article proposes a new apparatus for thermal conductivity comparison where the working principle is mainly based on relative measurement rather than absolute measurement. The measuring circuit and data processing steps are explained in detail; a validation test was performed using the well-known glycerine and engine oil.

A License-Plate Image Binarization Algorithm Based on Least Squares Method for License-Plate Recognition of Automobile Black-Box Image (블랙박스 영상용 자동차 번호판 인식을 위한 최소 자승법 기반의 번호판 영상 이진화 알고리즘)

  • Kim, Jin-young;Lim, Jongtae;Heo, Seo Weon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.5
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    • pp.747-753
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    • 2018
  • In the license-plate recognition systems for automobile black Image, the license-plate image frequently has a shadow due to outdoor environments which are frequently changing. Such a shadow makes unpredictable errors in the segmentation process of individual characters and numbers of the license plate image, and reduces the overall recognition rate. In this paper, to improve the recognition rate in these circumstance, a license-plate image binarization algorithm is proposed removing the shadow effectively. The propose algorithm splits the license-plate image into the regions with the shadow and without. To find out the boundary of two regions, the algorithm estimates the curve for shadow boundary using the least-squares method. The simulation is performed for the license-plate image having its shadow, and the results show much higher recognition rate than the previous algorithm.

Reinforcement Learning based Dynamic Positioning of Robot Soccer Agents (강화학습에 기초한 로봇 축구 에이전트의 동적 위치 결정)

  • 권기덕;김인철
    • Proceedings of the Korean Information Science Society Conference
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    • 2001.10b
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    • pp.55-57
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    • 2001
  • 강화학습은 한 에이전트가 자신이 놓여진 환경으로부터의 보상을 최대화할 수 있는 최적의 행동 전략을 학습하는 것이다. 따라서 강화학습은 입력(상태)과 출력(행동)의 쌍으로 명확한 훈련 예들이 제공되는 교사 학습과는 다르다. 특히 Q-학습과 같은 비 모델 기반(model-free)의 강화학습은 사전에 환경에 대한 별다른 모델을 설정하거나 학습할 필요가 없으며 다양한 상태와 행동들을 충분히 자주 경험할 수만 있으면 최적의 행동전략에 도달할 수 있어 다양한 응용분야에 적용되고 있다. 하지만 실제 응용분야에서 Q-학습과 같은 강화학습이 겪는 최대의 문제는 큰 상태 공간을 갖는 문제의 경우에는 적절한 시간 내에 각 상태와 행동들에 대한 최적의 Q값에 수렴할 수 없어 효과를 거두기 어렵다는 점이다. 이런 문제점을 고려하여 본 논문에서는 로봇 축구 시뮬레이션 환경에서 각 선수 에이전트의 동적 위치 결정을 위해 효과적인 새로운 Q-학습 방법을 제안한다. 이 방법은 원래 문제의 상태공간을 몇 개의 작은 모듈들로 나누고 이들의 개별적인 Q-학습 결과를 단순히 결합하는 종래의 모듈화 Q-학습(Modular Q-Learning)을 개선하여, 보상에 끼친 각 모듈의 기여도에 따라 모듈들의 학습결과를 적응적으로 결합하는 방법이다. 이와 같은 적응적 중재에 기초한 모듈화 Q-학습법(Adaptive Mediation based Modular Q-Learning, AMMQL)은 종래의 모듈화 Q-학습법의 장점과 마찬가지로 큰 상태공간의 문제를 해결할 수 있을 뿐 아니라 보다 동적인 환경변화에 유연하게 적응하여 새로운 행동 전략을 학습할 수 있다는 장점을 추가로 가질 수 있다. 이러한 특성을 지닌 AMMQL 학습법은 로봇축구와 같이 끊임없이 실시간적으로 변화가 일어나는 다중 에이전트 환경에서 특히 높은 효과를 볼 수 있다. 본 논문에서는 AMMQL 학습방법의 개념을 소개하고, 로봇축구 에이전트의 동적 위치 결정을 위한 학습에 어떻게 이 학습방법을 적용할 수 있는지 세부 설계를 제시한다.

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3-D Frame Design Using Second-Order Plastic-Hinge Analysis Accounting for Lateral Torsional Buckling (횡비틀림좌굴을 고려하는 2차 소성힌지해석을 이용한 3차원 강뼈대 구조물 설케)

  • 김승억;박주수
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.15 no.1
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    • pp.117-126
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    • 2002
  • In this paper, 3-D fame design using second-orders plastic-hinge analysis accounting for lateral torsional buckling is developed. This analysis accounts for material and geometric nonlinearities of the structural system and its component members. Moreover, the problem associated with conventional second-order plastic-hinge analyses, which do not consider the degradation of the flexural strength caused by lateral torsional buckling, is overcome. Efficient ways of assessing steel frame behavior including gradual yielding associated with residual stresses and flexure, second-order effect, and geometric imperfections are presented. In this study, a model consisting of the unbraced length and cross-section shape is used to account for lateral torsional buckling. The proposed analysis is verified by the comparison of the LRFD results. A case studs shows that lateral torsional buckling is a very crucial element to be considered in second-order plastic-hinge analysis. The proposed analysis is shown to be an efficient reliable tool ready to be implemented into design practice.