• Title/Summary/Keyword: 갑상선 기능 검사

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Primary Hypoparathyroidism in a Miniature Schnauzer Dog (미니어처 슈나우저에서 발생한 원발성 부갑상선기능저하증)

  • Kang, Min-Hee;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.26 no.6
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    • pp.603-605
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    • 2009
  • A 7-year-old intact female, Miniature Schnauzer dog was presented with an acute seizure episode and tremors. Fever and panting were noted when presented. Physical examination revealed apparent forelimb muscle rigidity, fasciculations and stiff gait. Characteristic laboratory findings in this dog were severe hypocalcemia with hyperphosphatemia. The low serum concentration of intact parathyroid hormone and ionized calcium levels were consistent with the diagnosis of primary hypoparathyroidism. In addition, there were increased urinary excretion of calcium and decreased urinary excretion of phosphorus in this case. Urgent treatment was initiated with 10% calcium gluconate. The dog remained healthy with vitamin D analogue and oral calcium supplementation. A transient hyperphosphatemia was controlled well with sevelamer hydrochloride. To the author's knowledge, this is the first case report describing the clinical and laboratory characteristic features of canine primary hypoparathyroidism and its clinical outcome in Korea.

Evaluation of the Congenital Hypothyroidism for Newborn Screening Program in Korea: A 14-year Retrospective Cohort Study (한국인 선천성 갑상선기능저하증에 대한 신생아선별검사의 14년간의 후향적 연구; 발생빈도와 유효성)

  • Yoon, Hye-Ran;Ahn, Sunhyun;Lee, Hyangja
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.19 no.1
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    • pp.1-11
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    • 2019
  • Purpose: Congenital hypothyroidism (CH) is the most common congenital endocrine disorder. The purpose of the present study was to determine the incidence of CH in South Korea during the period from January 1991 to March 2004. Methods: Central data from each city branch of SCL (Seoul Clinical Reference Laboratories) in Yongin, South Korea, was gathered and collectively analyzed. Newborn screening (NBS) for CH was based on measuring the levels of neonatal thyroid stimulating hormone (TSH) and free T4 (a cut-off of 20 mIU/L and less than 0.8 ng/dL, respectively). Results: During the study period, 671,805 live births were screened for CH based on TSH and free T4 ELISA assays. A total of 159 newborns were deemed positive for CH out of 671,805, with a corresponding incidence of 1 in 4,225. When a cut-off of 20 mIU/L was used in TSH assays, the associated sensitivity, specificity, and positive predictive values (PPV) were 100.0%, 99.7%, and 10.8%, respectively. When a cut-off of 0.8 ng/dL in free T4 assays was used, the associated sensitivity, specificity, and PPV were 100.0%, 98.5%, and 3.9%, respectively. Conclusion: CH incidence in South Korea as evidenced by the results of NBS was compared with its incidence and comparable to the other countries prior to 2004.

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Congenital Cystic Diseases in the Neck - I. Branchial Cysts, II. Thyroglossal Duct Cysts (선천성 경부 낭종 -I. 측경새성낭종 3예, II. 갑상선설관낭종 4예-)

  • 노관택;김대성
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1972.03a
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    • pp.16.2-16
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    • 1972
  • Persistance of developmental remnants during fetal life may be attributed to congenital cysts and fistulas in the neck, which are experienced rather rarely. Recently authors have experienced three cases of progressive increased tumor mass in the lateral side of the neck and four cases of tumor mass in the suprathyroid region. We have performed surgical removal under the diagnosis of branchial cysts and thyroglossal duct cysts, respectively. The biopsy specimens were confirmed by histopathological study.

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건강토픽

  • KOREA ASSOCIATION OF HEALTH PROMOTION
    • 건강소식
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    • v.2 no.10 s.13
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    • pp.40-47
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    • 1974
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The Usefulness of $^{99m}Tc$-Sestamibi Scan in Preoperative Localization in Primary Hyperparathyroidism (원발성 부갑상선 기능 항진증의 수술전 병소확인에서 $^{99m}Tc$-Sestamibi 스캔의 유용성)

  • Baik, S.H.;Kim, S.M.;Choi, K.M.;Choi, Y.S.;Kim, S.J.;Yu, J.M.;Choi, D.S.;Choe, J.C.
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.4
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    • pp.465-472
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    • 1995
  • An accurate preoperative localization in patients with primary hyperparathyroidism is important for successful surgical intervention. There are many methods for the localization of the primary hyperparathyroidism such as ultrasonography, computerized tomography(CT), magnetic resonance imaging(MRI), angiography and $^{201}T1/^{99m}Tc$ subtraction scan. Among them $^{201}T1/^{99m}Tc$ subtraction scan is known as the most accurate tool for preoperative localization. Recently $^{99m}Tc$-Sestamibi has been used for parathyroid gland imaging. We experienced 19 primary hyperparathyroidisms accurately localized with $^{201}T1/^{99m}Tc$ subtraction imaging and $^{99m}Tc$-Sestamibi. The sensitivities of the $^{99m}Tc$-Sestanibi, $^{201}T1/^{99m}Tc$ subtraction imaging, CT and US were 100%(5/5), 89.5%(17/19) and 61.7(12/19) respectively. With the combination of $^{99m}Tc$-Sestamibi and $^{201}T1/^{99m}Tc$ subtraction imaging we could localize with 100% accuracy. Although the case number is small, this study suggests that the $^{99m}Tc$-Sestamibi parathyroid scan is very useful and easy to use for preoperative localization in primary hyperparathyroidism.

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