• Development and Reproduction
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• v.13 no.4
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• pp.291-296
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• 2009

In most larvae of ascidian, two sensory pigment cells, otolith and ocellus, lie in their brain vesicle. They also have a third type of sensory cells: hydrostatic pressure receptor (Hpr) cells. The Hpr cells were presumed to be hydrostatic pressure-detection cells, but their precise functions is still disputed. In this study, we investigated whether an FGF signaling is involved in formation of Hpr cells. When fertilized eggs were injected with Hr-FGF9/16/20 antisense MO, the resulting larvae showed severe abnormalities with no expression of the Hpr cell-specific Hpr-1 antigen. Similar results were obtained using an FGF receptor inhibitor, SU5402, and an MEK inhibitor, U0126. Embryos treated with SU5402 or U0126 during the 32-cell and hatching stages did not express the Hpr-1 antigen. To elucidate the temporal requirement for the FGF signaling in formation of Hpr cells, embryos were treated with SU5402 for 2 h, or U0126 for 20 min during various embryonic stages. Larvae treated with SU5402 from the 16-cell stage to the 64-cell stage did not express the Hpr-1 antigen, whereas those treated at the early gastrula stage expressed the Hpr-1 antigen. When U0126 treatment was carried out at various stages between the 8-cell and late gastrula stages, larvae scarcely formed the Hpr cells. They showed expression of the Hpr-1 antigen when embryos were placed in U0126 just before the neural plate stage. These results suggest that FGF9/16/20 signaling is involved in formation of Hpr cells from the primary neural induction stage to the late gastrula stage.

• Journal of Korean Orthopaedic Sports Medicine
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• v.6 no.2
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• pp.92-98
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• 2007

Purpose: We evaluated the clinical results of arthroscopic ACL reconstruction using quadrupled hamstring tendon with tibial remnant-preserving technique. Materials and Methods: Thirty-five cases were evaluated from Feb, 2003 to May, 2006. The average interval from injury to surgery was $2.6{\pm}1.6$ months. The cause of injury was mostly sports-related trauma. The average follow-up period was 17 months. Tibial remnant was preserved as much as possible and caution was taken not to damage the remnant during ACL reconstruction. Postoperative rehabilitation was the same as the usual rehabilitation method after ACL reconstruction, except for delaying motion for 2 weeks with an extension locking brace. Clinical evaluation was performed using ROM; Lachman test; pivot-shift test; anterior displacement measurement using KT-2000 arthrometer; Lysholm score and proprioception measured by single limb standing test. Results: There was no limitation of knee motion without contracture. The Lachman test and pivot-shift test were both negative. The side-to-side difference of anterior displacement measured using KT-2000 arthrometer was improved from 6.7 mm to 2.2 mm. The average Lysholm score improved from 81 to 96. The single limb standing test for proprioceptive evaluation showed no significant difference from a normal leg. Conclusion: ACL reconstruction with tibial remnant-preserving technique can preserve mechanoreceptors with prorioception and expect good functional recovery.

• The Journal of Korean Academy of Sensory Integration
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• v.7 no.1
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• pp.59-69
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• 2009

Objective : The purpose of the study is to examine the length of institutionalization and sensory modulation for preschooler without disabilities, and to investigate the relationship between the length of institutionalization and behavioral problem. Method : Mothers of preschoolers without disabilities between ages of 3 and 7 who attend D kindergarten was participated. Nursery school teacher of institutionalized children without disabilities between ages of 3 and 7 who attend child-welfare facilities was participated. We used Short Sensory Profile(SSP) and Children Behavior Check list. The results were analyzed with SPSS 11.0. Results : There was no significant difference between longer length of institutionalization and shorter length of institutionalization in sensory modulation and behavioral problem. Regarding the sensory modulation and behavior problem according to child-welfare facilities, means showed the statistically significant difference. Regarding sensory modulation of test items, movement sensitivity and low energy/weak showed the statistically significant difference in home-reared children than institutionalized children. Conclusions : The results of the study showed high correlation environmental effect in institutionalized children. Further research is needed to improve environmental for institutionalized children.

• Korean Institute of Interior Design Journal
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• v.22 no.1
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• pp.291-298
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• 2013

A science museum responds independently based on the exhibits and exhibition environments as the visitors are different in purposes, interests and demands. Therefore a science museum should be designed keeping it in mind that there are various ways for visitors to perceive and use the exhibition spaces and exhibits. The purpose of this study is to compare and analyze the characteristics of sensory receptors for the exhibits in National Museum of Nature and Science's Global Gallery, Tokyo, in terms of information transmission and to identify the nature of exhibit medium that can affect the perception and recognition of the exhibits by visitors. Through these 9 sensory receptors, human recognizes first with visual, auditory and olfactory senses and reacts using vestibular organ, proprioceptor (stretch), tangoreceptor, themoreceptor, taste and olfactory senses. Human uses these information processing to recolonize the external environment. This process is similar to the visitor's information transmission process for the exhibition medium. By dividing the analysis results per exhibition theme and developing the information transmission processing types per sensory receptor, we could understand that the distribution conditions are closely connected with the composition of the exhibition scenario in the exhibtion area. Especially, the understanding of how the information transmission is made through sensory receptors could can be the criteria that determines on the factors that can identify the exhibition purposes of a science museum which are eduction and understanding.

• Applied Microscopy
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• v.39 no.2
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• pp.141-147
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• 2009

The antennae of millipedes have a prominent function in detecting various types of environmental stimuli, and structural modification of the antennae is closely associated with the degree of sense recognition. Although the biological significance of the antennal sensillae to millipedes are widely understood, the structure and function of the antennal sensillae are still not clear and more precise analysis is required. We have analysed the ultrastructural characteristics of the antennal sensillae in a millipede Anaulaciulus koreanus koreanus using field emission scanning electron microscopy (FESEM). According to their morphological and substructural features, we could identify three different types of antennal sensillae as follows: trichoid sensilla (TS), chaetiform sensilla (CS) and basiconic sensilla (BS). The TS on the articles are long, blunt-tipped, almost straight hairs with deep longitudinal grooves in their lower parts whereas, the CS are long, sickleshaped bristles with longitudinal grooves acuminating toward the tip. The BS can be subdivided further into three subtypes which are the large-sized basiconic sensilla ($BS_1$), the small-sized basiconic sensillae ($BS_2$) and the spiniform basiconic sensillae ($BS_3$). The BS between the terminal segment and distal margins of the other segments are clearly discriminated in this species.

• Journal of Biomedical Engineering Research
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• v.23 no.2
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• pp.165-170
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• 2002

The aim of this study was to analyze the effect of different sensory information on the motor function which is resulted from visual stimuli. Particularly, it was focused on the effect of complementary color stimuli on reaction time. Twenty volunteers(10 men & 10 women), between the age of 20 and 25 yearn participated in this experiment. Experiments were carried out in a light & sound-attenuated chamber, and the overall system consisted of a PC. interface card. LEDs. key board switch, and display panel. Although many measurements of sensory-motor integration has been studied the quantitative analysis of sensory-motor integration has not been developed well. Quantitative analyses were performed to investigate the effect of the different sensory information on the arm motor system in the point of view sensory-motor integration. The result showed that the reaction time for visual stimuli of complementary colors was faster than that under same color environments : and, in same color environments and the reaction speed was varied inversely with respect to the magnitude of the light wavelength.

• Restorative Dentistry and Endodontics
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• v.25 no.3
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• pp.407-420
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• 2000

삼차신경절의 뉴런이 구강악안면영역에서의 촉각, 입각, 온도각 및 통각 등 다양한 감각을 중추신경계로 전달하는 역할을 하는 것은 주지의 사실이다. 이러한 신경전달에 있어서 이온통로는 감각정보를 전달하는데 핵심적인 역할을 수행하며 특히 소디움 통로는 활동전위의 발생에 중요하다. 소디움 통로는 tetrodotoxin-sensitive(TTX-s) 및 tetrodotoxin-resistant(TTX-r) 통로로 나누어지는 데 이 중 TTX-r 통로에 발생되는 tetrodotoxin-resistant sodium current(TTX-r $I_{Na}$)는 capsaicin에 민감한 일차구심신경세포에서 유해자극에 의해 통각신호를 발생시키고 전달하는데 중요하다. 또한 칼슘 통로는 시냅스 전도에 있어서 필수적인 역할을 수행하고 있다 한편 치과영역에서 치수의 진정 목적으로 eugenol이 흔히 사용되고 있다. 그러나 eugenol의 그 작용 기전에 대해서 현재까지 이온 통로에 대한 상세한 결과가 없는 실정이며 최근의 보고에 의하면 eugenol이 capsaicin 수용기를 통하여 감각신경에 대한 억제작용을 나타낸다고 한다. 따라서 본 실험은 eugenol과 capsaicin이 흰쥐의 삼차신경절의 TTX-r $I_{Na}$와 칼슘통로에 어떠한 영향을 미치는지를 알아보고 eugenol이 capsaicin 수용기를 통하여 작용하는지를 검증하고자 시행되었다. 삼차신경절 뉴런은 100~150g의 흰쥐의 삼차신경절로부터 외과적으로 절제하여 통법의 화학적 및 기계적 처리를 통해 단일세포로 분리하였고 이를 whole-cell patch clamp 방법을 이용하여 시행한 바 다음과 같은 결론을 얻었다. 1. 1mM의 dugenol은 흰쥐 삼차신경절 뉴런의 TTX-r $I_{Na}$와 HVA $I_{Ca}$를 억제하였다. 2. $1{\mu}m$의 capsaicin은 흰쥐 삼차신경절 뉴런의 TTX-r $I_{Na}$와 HVA $I_{Ca}$를 억제하였다. 3. Capsazepine은 capsaicin의 HVA $I_{Ca}$에 대한 억제작용을 차단하였다. 4. Capsazepine은 capsaicin의 HVA $I_{Ca}$에 대한 억제작용을 차단하지 못하였다. 결론적으로 eugenol과 capsaicin은 tetrodotoxin-resistant sodium current(TTX-r $I_{Na}$)와 high voltage-activated calcium current(HVA $I_{Ca}$)를 모두 억제하는 것으로 나타났으며, 이러한 작용이 통각의 발생과 시냅스 전달과정을 차단하여 치수 진정 목적으로 많이 사용하는 eugenol의 작용기전으로 판단된다. 한편 capsaicin의 길항제인 capsazepine을 전처치하였을 때에도 eugenol의 HVA $I_{Ca}$에 대한 억제효과는 변화가 없었다. 이와같은 결과로 보아 HVA $I_{Ca}$에 관한 한 eugenol은 capsaicin 수용기를 통하여 나타나지 않는 것으로 사료된다.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2000.10a
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• pp.21-22
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• 2000

생물의 특성 중 하나는 외부나 내부의 자극에 대하여 반응한다는 것이다. 이러한 환경의 변화를 감각기관에서 수용하여 그 환경의 변화에 적절하게 대응하는데 이러한 반응은 작게는 운동, 크게는 행동이라는 형태로 나타난다. 동물에 있어서 이와 같이 자극에 대하여 특이한 반응행동을 일으키는 성질들을 주성(Taxis)이라 한다. 주성에는 자극에 따라 주광성, 주촉성, 주류성, 주온성 등이 있으나 어업에 있어서 가장 광범위하게 이용하고 있는 것이 어류의 주광성이라 할 수 있다. (중략)

• Journal of rehabilitation welfare engineering & assistive technology
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• v.10 no.4
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• pp.279-285
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• 2016

Reliable recording and analysis of peripheral nerve activity is important to recognize the user's intention for controlling a neuro-prosthetic hand. In this paper, we present a peripheral nerve recording system that consisted of an intrafascicular multi-electrode array, an electrode insertion device, and a multi-channel neural amplifier. The 16 channel multi-electrode array was stably implanted into the sciatic nerve of the rat under anesthesia using the electrode insertion device. During passive movements and mechanical stimuli, muscle and cutaneous afferent signals were recorded with the multi-channel neural amplifier. Furthermore, we propose a spike sorting method to isolate individual neuronal unit. The muscle proprioceptive units were classified as muscle spindle afferents or Golgi tendon organ afferents, and the skin exteroceptive units were categorized as slow adapting afferents or fast adapting afferents. Experimental results showed that the proposed method could be applicable to record and analyze peripheral nerve activity in neuro-prosthetic systems.

• Korean Journal of Ichthyology
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• v.26 no.4
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• pp.281-287
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• 2014

An olfactory organ in Scartelaos gigas, so-called mudskipper known as adaptation to an amphibious lifestyle, was investigated anatomically and histologically. S. gigas possessed the paired olfactory organ comprising respectively the one elongated canal and two nasal sacs, lacrimal and ethmoidal nasal sac. The sensory epithelium developed partly in the canal contained four distinct types of cells: (1) receptor cell with 3 to 4 cilia in number, (2) supporting, (3) basal, (4) mucus cell. The sensory epithelium was also of transitional layer as multi cellularity structure. The non-sensory epithelium had no sensory elements. The two nasal sacs possessed typically a lot of mucin droplets. These results might be considered that anatomical structure and histological characters of the olfactory organ showing in S. gigas is adapted to semi-aquatic life associated with its ecological habit and habitat.