• Title/Summary/Keyword: 간 질환

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Podiatric Clinical Diagnosis using Decision Tree Data Mining (결정트리 데이터마이닝을 이용한 족부 임상 진단)

  • Kim, Jin-Ho;Park, In-Sik;Kim, Bong-Ok;Yang, Yoon-Seok;Won, Yong-Gwan;Kim, Jung-Ja
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.48 no.2
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    • pp.28-37
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    • 2011
  • With growing concerns about healthy life recently, although the podiatry which deals with the whole area for diagnosis, treatment of foot and leg, and prevention has been widely interested, research in our country is not active. Also, because most of the previous researches in data analysis performed the quantitative approaches, the reasonable level of reliability for clinical application could not be guaranteed. Clinical data mining utilizes various data mining analysis methods for clinical data, which provides decision support for expert's diagnosis and treatment for the patients. Because the decision tree can provide good explanation and description for the analysis procedure and is easy to interpret the results, it is simple to apply for clinical problems. This study investigate rules of item of diagnosis in disease types for adapting decision tree after collecting diagnosed data patients who are 2620 feet of 1310(males:633, females:677) in shoes clinic (department of rehabilitation medicine, Chungnam National University Hospital). and we classified 15 foot diseases followed factor of 22 foot diseases, which investigated diagnosis of 64 rules. Also, we analyzed and compared correlation relationship of characteristic of disease and factor in types through made decision tree from 5 class types(infants, child, adolescent, adult, total). Investigated results can be used qualitative and useful knowledge for clinical expert`s, also can be used tool for taking effective and accurate diagnosis.

Drug Interactions between Cardiovascular Agents and Psychotropic Drugs (심혈관질환약물과 향정신성약물의 약물상호작용)

  • Park, Joo-Eon;Jung, Kyung-Hee
    • Korean Journal of Psychosomatic Medicine
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    • v.19 no.2
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    • pp.57-65
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    • 2011
  • There are numerous drug interactions related to many psychotropic and cardiovascular medications. Firstly, the principles in predicting drug interactions are discussed. Cytochrome P (CYP) 450 plays a significant role in the metabolism of these drugs that are substrates, inhibitors, or inducers of CYP450 enzymes. The two most significant enzymes are CYP2D6 and CYP3A4. The ability of psychotropic drugs to act as inhibitors for the enzymes may lead to altered efficacy or toxicity of co-administered cardiovascular agents as a substrate for the enzymes. The following is also a review of the known interactions between many commonly prescribed cardiovascular agents and psychotropic drugs. Most beta blockers are metabolized by CYP2D6, which may lead to drug toxicity when they use in combination with potent CYP2D6 inhibitors including bupropion, chlorpromazine, haloperidol, selective serotonin reuptake inhibitors, and quinidine. Concomitant administration of lithium with angiotensin converting enzyme inhibitors, angiotensin receptor blockers, and diuretics may increase serum lithium concentrations and toxicity. Calcium channel blockers and cholesterol lowering agents are subject to interactions with potent inhibitors of CYP3A4, such as amiodarone, diltiazem, fluvoxamine, nefazodone, and verapamil. Prescribing antiarrhythmic drugs in conjunction with medications are known to prolong QT interval and/or inhibitors on a relevant CYP450 enzyme is generally not recommended, or needs watchful monitoring. Digoxin and warfarin also have warrant careful monitoring if co-administered with psychotropic drugs.

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Recognition for Lung Cancer using PCA in the Digital Chest Radiography (디지털 흉부영상에서 주성분분석을 이용한 폐암인식)

  • Park, Hyung-Hu;Ok, Chi-Sang;Kang, Se-Sik;Ko, Sung-Jin;Choi, Seok-Yoon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.7
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    • pp.1573-1582
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    • 2011
  • Risk of lung cancer among lung-related diseases has gradually increased during last decades. The chest digital radiography is the primary diagnosis method for lung cancer. Diagnosing lung cancer using this method requires doctors of ripe experience. Despite their experience there are often wrong diagnoses, which decrease early diagnosis and survival rates of patients. The aim of this study was intended to establish the base on the Computer Aided Diagnosis (CAD) by analyzing Image Recognition Algorithm using Principle component Analysis (PCA) and diagnosing patient's chest X-ray image. The database obtained through this approach enables a doctor to significantly reduce misdiagnosis during the early diagnosis stage, if he or she utilizes it as the preliminary reading step. Case studies were carried out using normal organ, and organs suffering from bronchogenic carcinoma and granuloma. A normal image and unique disease images were extracted after PCA analysis, and their cross-recognition efficiency were compared each other. The result revealed that the recognition rate was much high between normal and disease images, but relatively low between two disease images. In order to increase the recognition efficiency among chest diseases the related algorithms have to be developed continuously in the future study, and such effort will establish the resolute base for CAD.

Comparison of Diagnostic Accuracy of Three-Dimensional MR Cholangiopanceatography and ERCP in Various Extrahepatic Biliary Lesions (여러 간외담도 질환에서 삼차원적 자기공명 췌담관 조영술과 내시경적 역행성 췌담관 조영술과의 비교: 진단적 정확성을 중심으로)

  • 김경숙;이문규;김명환;이승규;김표년;오용호
    • Investigative Magnetic Resonance Imaging
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    • v.1 no.1
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    • pp.148-153
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    • 1997
  • Purpose: To evaluate the diagnostic role of a three-dimensional MR cholangiopancreatography (MRCP) over endoscopic retrograde cholangio-pancreatography (ERCP) in various extrah-epatic biliary disease. Materials and Methods: MRCP and ERCP were performed in 45 consecutive patients with suspected extrahepatic biliary diseases. MRCP was obtained using a reverse fast imaging with a steady-state free precession (reverse FISP: PSIF) sequence, and then images were reconstructed by standard MIP algorithm. The predictability of biliary dilatation and level of obstruction of MRCP was evaluated using ERCP as a gold standard. The accuracy distinguishing malignant from benign lesions, and overall diagnostic accuracy were compared between MRCP and ERCP. Results: The sensitivity, specificity and accuracy of MRCP in predicting biliary dilatation were 94.6%, 75.0% and 91.1%, respectively. The level of obstruction was accurate in 87.0% with MRCP. The sensitivity, specificity and accuracy of MRCP and ERCP in distinguishing malignant from benign lesions were 76.2%, 87.5% and 82.2% and 71.4%, 83.3% and 77.8%, respectively. The overall diagnostic accuracy was 60.0% with MRCP and 55.6% with ERCP. Conclusion: 3D MRCP shows a good diagnostic value compared to that of ERCP, and can replace a ERCP.

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$^{99m}Tc-DISIDA$ Hepatobiliary Scintigraphic Study in Symptomatic Patients after Various Biliary Surgeries: Regional Emphasis of Recurrent Pyogenic Cholangitis and Intrahepatic Duct Stones (담도계 수술후 증상이 재발한 환자에서의 $^{99m}Tc-DISIDA$ Hepatobiliary Scintigraphy: 재발 농양성 간담도염과 간내 담석 발생빈도의 지역적인 특성을 고려한 연구)

  • Yum, H.Y.;Park, Y.H.;Suh, J.K.;Lee, S.D.;Choi, K.H.
    • The Korean Journal of Nuclear Medicine
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    • v.20 no.2
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    • pp.19-38
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    • 1986
  • 54 patients who had symptoms after biliary operation were studied by $^{99m}Tc-DISIDA$ hepatobiliary scintigraphy for evaluation of clinical utility, with regional emphasis of recurrent pyogenic cholangitis (RPC) and intrahepatic stones. As expected, the most common disease was recurrent pyogenic cholangitis regardless of surgical anastomosis, 58% and next frequent disease was clonorhis sinensis infestation, 26%, stenosis of ampula vater 8%, and chronic hepatitis 4% (20% of patients had hepatitis but they showed clinically and scintigraphically dominallt combined disease feature). 87% of recurrent pyogenic cholangitis was associated with stones in intra or/and extrahepatic ducts and only 11.4% of RPC was found to be associated with Cs-infestation. The scintigraphic diagnosis of RPC was 81.6% and 78.6% of stones was detected by indirect visualization of scintigraphy findings and 71.7% of Cs-infestation was detected by scintigraphy. The characteristic bile flow pattern were described.

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Mental Health and Quality of Life by Type-D Personality of the Patients with Coronary Artery Disease (D 유형 성격에 따른 관상동맥질환자의 정신건강과 삶의 질)

  • Cha, KyeongSook;Im, SuMi;Cho, Ok-Hee
    • The Journal of the Korea Contents Association
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    • v.13 no.5
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    • pp.286-294
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    • 2013
  • The purpose of this study was to confirm the mental health and quality of life by type-D personality of the patients with coronary artery disease (CAD). The participants in the study were 111 hospitalized patients with CAD at a hospital in Gyeonggi-do. The type-D personality was assessed by the Type-D Personality Scale (DS14). The mental health was measured with Symptom Checklist-90-Revision (SCL-90R) while quality of life was assessed with World Health Quality of Life Assessment Instrument (WHOQOL-BREF). The data analysis revealed that 36.1% of CAD patients were identified as having type-D personality traits. Non type-D personality patients have shown better mental health state than type-D personality patients (p<.001) have. The level of quality of life in the type D personality patients were significantly lower than that of non type-D counterparts (p<.001). It is necessary for type-D personality to be considered, when the nursing intervention programs for improving the mental health and quality of life of the patients with CAD are developed.

Clinical Observation of the Pulmonary Aspergilloma (폐국균종(Plulmonary Aspergilloma)의 임상적 고찰)

  • Kim, Hyeung-Il;Kim, Sung-Sook;Chung, Jin-Hong;Lee, Kwan-Ho;Lee, Hyun-Woo
    • Journal of Yeungnam Medical Science
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    • v.10 no.1
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    • pp.157-165
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    • 1993
  • The authors conducted a clinical observation of 13 cases of pulmonary aspergilloma at Yeungnam University Hospital from March 1983 to March 1992, and the following results were observed : 1) The male to female ratio was 1 : 1.2, and the age distribution was ranged 30 to 67 years old. 2) All cases were symptomatic : hemoptysis, cough, sputum and dyspnea. Especially, hemoptysis was the presenting compliant in 10 patients(77%). 3) The underlying lung disease were pulmonary tuberculosis in 9, COPD in 5 and bronchiectasis in 2, 3 cases were without underlying disease. 4) According to radiographic appearance, 8 cases had the typical crescent sign and 5 cases were seen nodular lesion. And the lesions of 11 cases were located in both upper lung. 5) 10 cases were treated with surgical resection. Among these cases, 8 cases were alieved and 2 cases, died. And other 3 cases were treated with conservative treatment. We suggest that these findings would be helpful for the diagnosis and treatment of pulmonary aspergilloma and further study might be needed to evaluate the prognosis of pulmonary aspergilloma.

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A study on the oral health status for each type of Disabilities (장애유형별 구강건강실태에 관한 조사)

  • Ko, Mi-Hee
    • Journal of dental hygiene science
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    • v.4 no.1
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    • pp.39-44
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    • 2004
  • The primary purpose of this report is to investigate the index of dental caries experiences and the state of oral hygiene for the children with mental retardation, cerebral palsy, and autism. In order to get those things we investigated 99 students that ages from 8 to 13 in three special schools (which are the school for the children with mental retardation, physical difficulties, emotional disturbance). Then collected the statistics and examined if there were some regardful differences among each type. (1) The investigation shows that there is no regardful differences among them in statistice. However, the averages of their dental caries experience have a little gap. The average of the children with mental retardation group is the highest and the autistic children group is the lowest, as we can see the facts of 4.70 for group of children with mental retardation, 4.58 for group of children with cerebral palsy, 3.67 for group of autistic children, children with mental retardation group is severe, autistic children group is few. (2) The conclusion from research of oral hygiene among each type, statistically regardful differences were revealed (p<0.05). It shows children with cerebral palsy is on worst state, children with mental retardation is on next state, autistic children is on best state by compare for averages among each type, 32.30 for group of children with mental retardation 35.00 for group of children with cerebral palsy, 27.79 for autistic children.

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Radiologic Features and Surgical Outcome of Juxtafacet Cyst Associated with Degenerative Lumbar Disease (퇴행성 요추 질환에서 발생한 후관절 근접 낭종의 방사선적 특징 및 수술의 결과)

  • Kim, Whoan Jeang;Chang, Shann Haw;Yang, Hwa Yeol;Kwon, Won Jo;Sung, Hwan Il;Park, Kyung Hoon;Choy, Won Sik
    • Journal of the Korean Orthopaedic Association
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    • v.52 no.1
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    • pp.65-72
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    • 2017
  • Purpose: The purpose of this study was to evaluate the radiologic features of juxtafacet cyst and determine the correlation between these features and clinical outcome. Materials and Methods: We analyzed a total of 23 patients. The degree of facet joint degeneration was classified using the Fujiwara method. The facet joint angles were measured with an magnetic resonance imaging to determine whether there was a difference between the cystic lesion that was occupied and the cystic lesion that was not occupied. Disc degeneration was measured by the Pfirrmann classification method. The clinical result was evaluated using the Oswestry disability index score and visual analogue scale. Results: The L4-5 level of juxtafacet cyst was mostly affected, as found in previous studies. Facet joint arthritis was more severe within the side with the cystic lesion. Significant correlation was found between disc degeneration and juxtafacet joint cyst. All patients underwent wide decompression and fusion. Clinical result was excellent. No patients had signs of recurrence during the follow-up periods. Conclusion: Juxtafacet cyst has a significant correlation with facet joint degeneration. Therefore, aggressive surgical treatment-not just simple cyst excision-should be considered as the treatment option for juxtafacet cyst associated with degenerative lumbar disease.

Health Status and Associated Health Risks among Female Marriage Immigrants in Korea (한국 여성결혼이민자의 건강상태와 건강위험요인)

  • Kim, Hye-Kyeong;Yoo, Seung-Hyun;Cho, Seon;Kwon, Eun-Joo;Kim, Su-Young;Park, Ji-Youn
    • Korean Journal of Health Education and Promotion
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    • v.27 no.5
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    • pp.79-89
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    • 2010
  • Objectives: This study aims to identify health status and health risks among female marriage immigrants to Korea and to provide a basis for public health strategies to address their health issues. Methods: The participants of the study were 3,069 immigrant wives. The health examination was conducted by the Korea Association of Health Promotion (KAHP) in 2008. The participants also completed self-administered questionnaires on demographic characteristics, health-related behaviors and mental health. Results: Patterns of immigrant women's health problems differed by age and country of origin. Behavior patterns also differed by their heritage, age, and years of residence in Korea. Generally Vietnamese women fell in lower ranges of disease prevalence and health risk factors in the participant group and Japanese women presented most healthy eating habits. Filipina women showed relatively high disease prevalence than any other group. Conclusion: Immigration to Korea by marriage is relatively a new phenomenon, thus continuing surveillance and research are needed to identify health risks, behavior patterns, and their relationships. Interventions and policies for the health of migrant wives, their children and families are required.