• Title/Summary/Keyword: 간 조직 검사

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Toxicity Evaluation of Irradiated Tarakjuk for Three Months (감마선 조사 타락죽의 3개월 반복투여 독성평가)

  • Yin, Xing Fu;Jeon, Young Eun;Kim, Tae-Keun;Shim, Jae-Hoon;Kang, Il-Jun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.11
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    • pp.1534-1539
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    • 2012
  • This study was conducted to evaluate the possible subacute toxicity of gamma-irradiated Tarakjuk. Tarakjuk was irradiated at a dose of 30 kGy at room temperature. For the animal study, AIN-93G as a control diet and 30 kGy irradiated and non-irradiated Tarakjuk diets were administered to male and female ICR mice (10 mice per group) for 3 months. During the experimental period, the group fed 30 kGy irradiated Tarakjuk did not show any changes in appearance, behavior, mortality, body weight, organ weight, or food consumption compared to control. Further, all biochemical parameters were in normal ranges. In the histopathological examination of liver and kidney tissues of ICR mice, there were no significant differences between the control and 30 kGy irradiated Tarakjuk groups. These results indicate that Tarakjuk irradiated at 30 kGy did not cause any toxic effects under these experimental conditions.

Vibrio anguillarum infection in rainbow trout Oncorhynchus mykiss during seawater adaption (해수순치 무지개송어 (Oncorhynchus mykiss)의 Vibrio anguillarum 감염증)

  • Kim, Si-Woo;Kim, Jong-Oh;Kim, Wi-Sik;Kim, Do-Hyung;Oh, Myung-Joo
    • Journal of fish pathology
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    • v.27 no.2
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    • pp.133-137
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    • 2014
  • We examined the cause of a disease outbreak in rainbow trout Oncorhynchus mykiss, which were adapting to a seawater in an aquaculture farm in Jeju on April, 2013. Most of the diseased fish showed a severe ulcer on the skin, enlarged spleen, expanded stomach and hemorrhage of abdominal and pyloric region. Although no parasites, fungi or viruses were isolated from diseased fish, over 200 same bacterial colonies were isolated from liver, spleen and kidney. Nucleotide sequences of the 16S rDNA gene of the bacterium in this study showed 100% identity with Vibrio anguillarum. This study is the first report of V. anguillarum infection in rainbow trout during sea adaption in Korea.

Clinical Significance of Tumor Markers in Gastric Cancer Patients after Curative Resection (근치적 절제술을 시행한 위암 환자에서 종양 표지자의 임상적 의미)

  • Kim, Sa-Young;Ha, Tae-Kyung;Kwon, Sung-Joon
    • Journal of Gastric Cancer
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    • v.9 no.3
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    • pp.136-142
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    • 2009
  • Purpose: This clinical study was conducted to evaluate the predictive value of tumor markers for recurrence and the clinical significance of false positive findings after curative gastrectomy in patients with gastric cancer. Materials and Methods: Two hundred ninety patients with gastric cancer who underwent gastrectomy with curative intent were evaluated retrospectively. We analyzed the correlations between changes in tumor markers (CEA, CA 19-9, AFP, and CA-125) and clinicopathologic data, and basis for changes in tumor markers without recurrence during the follow-up period. Results: The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of tumor markers for recurrence were 75.0%, 64.6%, 23.1%, 94.8%, and 65.9% respectively. Among 36 patients with recurrences, 10 patients (27.8%) had elevated tumor markers prior to positive findings on imaging studies, while 13 patients (36.1%) had concomitant elevation in tumor markers. At least 1 of the 4 tumor markers increased in 90 of 290 patients during the follow-up period; however, there was no evidence of tumor recurrence. Twenty patients had persistently elevated tumor markers, while the tumor marker levels in 70 patients returned to normal level within $9.08\pm7.2$ months. The patients with pulmonary disease, hepatobiliary disease, diabetes, hypertension, or herbal medication users had elevated tumor markers more frequently than patients without disease (P<0.001). Conclusion: Although detecting recurrence of gastric cancer with tumor markers may be useful, false positive findings of tumor markers are common, so surgeons should consider other chronic benign diseases and medical conditions when tumor markers increase without evidence of recurrence.

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Hepatic Parenchrmal Changes After Percutaneous Injection of Holmium-166 in Rabbit (가토 간내에 Holmium-166 주입 후의 간 실질 변화)

  • 최병인;김명진;박영년;김주희;최병욱
    • Investigative Magnetic Resonance Imaging
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    • v.5 no.1
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    • pp.43-48
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    • 2001
  • Purpose : To evaluate changes in rabbit liver parenchyma on MR images following percutaneous Holmium-166 injection, and to correlate those changes with histologic findings. Materials and methods. Holmium-166 (10-25 mCi) was percutaneously injected into the liver of rabbit (n=12) under sonographic guidance. MR images were obtained between one to two weeks (acute phasea) after the injection in four rabbits, and between two to four weeks (subacute phase) after the injection in four rabbits. Tissue specimens of these eight rabbits were obtained immediately after MR imaging. Tissue specimens were obtained without MR imaging in four rabbits (between one to two weeks in one rabbit and between three to four weeks in three rabbits). Results : Tissue specimens showed central liquefactive necrosis and peripheral coagulative necrosis containing deposition of small particles and hemorrhage. The peripheral margin of the lesions showed formation of the granulation tissue with fibrosis, which tended to be more prominent in subacute phase. The area of the necrosis tended to correlate with the dose of the radioactive Holmium-166. On MR images, the central portion of the necrosis showed hyperintensity on 72-weighted image, hypointensity on the precontrast T1-weighted images, and no enhancement on the dynamic MR images. The peripheral portion of the necrosis showed hypointensity on T2-weighted images, iso or mild hypointensity on the T1-weighted images, and mild peripheral enhancement on the delayed dynamic MR images. The peripheral margin of the lesion showed hypointensity on both T1- and T1-weighted images with increased enhancement on the delayed phase images of the dynamic MR images. Conclusion : After percutaneous Holmium-166 injection into rabbit liver parenchyma, the central portion showed liquefactive necrosis, the peripheral portion showed coagulative necrosis with granulation, fibrosis, hemorrhage and depostition of small granules. MR imaging may be helpful in evaluation of the histological change of the liver after percutaneous Holmium-166 treatment.

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The Relationship among Basic Vocational Competencies, Teaching Personality·Aptitude, and Behavior Type of Preschool Teachers (예비보육교사의 직업기초능력, 교직 인·적성, 행동유형 간의 관계)

  • Lim, Myeung Hee;Park, Yoon Joe;Kim, Seong-Hyun
    • Korean Journal of Child Education & Care
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    • v.17 no.4
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    • pp.145-161
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    • 2017
  • The purpose of this study was to analyze the relationship among NCS basic vocational competencies, Teaching Personality Aptitude and DISC behavior type of pre-preschool teachers. The subjects were 110 pre-preschool teachers attended in D university located in Kyonggido. 'NCS basic vocational competencies scale', 'Teaching Personality and Aptitude scale', and 'DISC behavior type scale' were used in the collection of data. It used Pearson's correlation Analysis to analyze the data. The results of this study are as follows; first, there was positive correlations between dominance trait and mathematical competency. And, there was positive correlations between interaction trait and self-development competency. And there were negative correlations between support traits and NCS basic vocational competencies. Second, it was revealed that positive correlations between almost sub scale's of NCS basic vocational competencies and teacher teaching personality aptitude. Third, there was positive correlations between dominance trait and sub scale of teaching personality aptitude(e.g.: problem solving/ inquiry skills, judgment, creativity/practical ability, leadership, knowledge/information ability, planning ability, sincerity/responsibility). And there were negative correlations between support traits and sub scale of teaching personality aptitude(e.g.: problem solving/ inquiry skills, judgment, creativity/practical ability, leadership, sincerity/responsibility).

Effect of Various Fat and Oil Types on Weight Gain and Liver Metabolism in Fasting or Normal Diet Rats (불포화도가 다른 유지가 단식과 정상식이 흰쥐의 체중 및 간대사에 미치는 영향)

  • 서화중;박현희
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.1
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    • pp.19-26
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    • 1993
  • In this study rats in fasting or fed protein free restricted diet including only fat showed much lowered level of serum cholesterol and triglyceride accompanied by utmost weight loss and high level of blood urea nitrogen indicated the tissue degradation, especially in liver with signs of damage or necrosis of hepatic parenchymal cell leading to elevated glutamic pyruvate transaminase value and to death. Rats fed only perilla oil in starvation or as fat source in normal diet dropped down the level of serum cholesterol and triglyceride compared to beef tallow fed rat. But with evidence of glutamic pyruvate transaminase values which was significantly elevated long term ingestion of perilla oil is likely to cause the lesion or any damage of hepatic function.

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Comparison of Radiographic Measurement and Clinical Parameters of Periodontal Condition on Premolars and Molars (소구치 및 대구치의 치주임상지수와 방사선학적 측정과의 상관관계에 대한 연구)

  • Lim, Hyun-Sook;Choi, Seong-Ho;Cho, Kyoo-Sung;Chai, Jung-Kiu;Kim, Chong-Kwan
    • Journal of Periodontal and Implant Science
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    • v.28 no.1
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    • pp.161-175
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    • 1998
  • 치주상태의 진단은 일반적으로 치주탐침과 같은 임상적 검사와 보조적으로 방사선 검사를 이용한다. 방사선학적인 검사가 치주조직의 파괴정도와 골 흡수를 진단하는데 유용하지만 실제적인 골 흡수를 정확하게 나타나는데는 한계가 있다고 하였다. 그리고 임상적 측정과 방사선 사진을 비교연구하여 이들간의 관계를 알아보고자 하는 노력이 있었다. 방사선이 임상에서 참고사항으로는 중요하지만 절대적 신뢰를 주는데는 문제가 있는 것으로 생각되어왔다. 방사선학적 측정과 임상지수 측정간의 상관관계에대하여 계속적인 연구를 통해 규명하는 것이 중요하다고 생각되어 저자는 연세대학교 치과 대학병원 치주과를 내원한환자중 연령 및 성별에 관계없이 전신질환이 없는 환자 130명을 대상으로 소구치의 원.근심부, 대구치의 원.중.근심부에서 치주낭의 깊이와 (P.D), 부착상실 (A.L)을 측정하였다. 방사선 사진상의 원.근심부에서 백악 법랑질 경계부에서 치조골능 상부까지의 치조골 수준 (Rx.B.L)을 측정하였고 이개부 부위에서는 이개부의 천정으로부터 나타나는 골 흡수의 방사선 투과상을 측정하였다. 이를 기초로 임상지수와 방사선학적 측정간에 상관관계를 연구하여 다음과 같은 결론을 얻었다. 1. 원·근심부의 P.D와 Rx.B.L을 비교 했을 때 상관관계는 모든 치아에서 높게 나타났다(r=0.897$\sim$r=0.725, p<0.01). 2. 원·근심부의 A.L와 Rx.B.L을 비교 했을 때 상관관계는 모든 치아에서 높게 나타났다 (r=0.915$\sim$r=0.732, p<0.01 ). 3. 대구치 769개가 실험 대상인었다. 상악 대구치중(356개) 40%가 이개부 병소를 나타냈고 (146개), 하악 대구치중(413개) 41%가 이개부 병소를 나타냈다(170개). 4. 대구치의 이개부 병소의 중앙부에서 측정한 P.D와 Rx.B.L을 비교 하였을 때 상관관계는 상악 제1대구치를 제외한 모든 치아에서 높게 나타 났다(r=0.811$\sim$r=0.435, p<0.01). 5. 대구치의 이개부 병소의 중앙부에서 측정한 A.L와 Rx.B.L을 비교 하였을 때 상관관계는 상악 제1대구치를 제외한 모든 치아에서 높게 나타 났다(r=0.906$\sim$r=0.479, p<0.01). 이상의 결과를 종합하여 볼 때 임상지수와 방사선학적 측정을 비교한 바, 이들의 상관관계는 모든 치아에서 밀접하게 나타났다. 따라서 방사선학적 측정은 임상지수와 더불어 치주질환의 진단과 치료계획에 크게 기여할 수 있을 것으로 사료된다.

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Development and Quality Properties of Cereal Bars (씨리얼바 제조 및 품질특성)

  • Han Sang-Ha;Kum Jun-Seok;Lee Hyun-Yu;Park Jong-Dae
    • Food Science and Preservation
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    • v.12 no.3
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    • pp.235-240
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    • 2005
  • The purpose of this study was to develop new functional cereal bars for breakfast with 9 types of cereal(corn, whole wheat, rice, brown rice, black rice, indian millet, sprouting brown rice, black soybean, job's tear) and their chemical and sensory properties were evaluated. Process of cereal bars are cereal mixing ${\to}$ formation ${\to}$ baking ${\to}$ cooling ${\to}$ topping. Moisture content of sunsik-type cereal bars were $9.4\%$, and puffed-type cereal bars were $10.1\%$. L-values of sunsik cereal bars were lower than that of puffed type cereal bars, and a-value was the highest in sunsik-type cereal bars with fructooligosaccaride. Texture measurement showed that hardness of sunsik-type cereal bars was higher than that of puffed-type cereal bars. Sensory evaluation resulted that sunsik-type cereal bars showed the high quality Score.

Detection for Contrast Media Extravasation using Bolus Tracking Systems of CT (CT Bolus Tracking System을 이용한 조영제의 혈관외유출 검출)

  • Kweon, Dae-Cheol;Lee, Yong-Gu
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.9
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    • pp.137-142
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    • 2016
  • When injecting intravenously of CT inspection, the effusion of the contrast meium can induce the tissue damage with the blood vessel outside. We detect extravasation which is generated in the course where we inject the contrast medium into the blood vessel. And we use the bolus tracking system for the detection of that. By using MPR and VR images, moreover we detected the extravasation in order to prevent the tissue damage. In order to detect the effusion of the contrast medium, we used 16-MDCT and 64-MDCT. Three dimensional images about the outflow of the blood vessel can provide the treatment information which is important in the patient treatment. Moreover we applied the image processing technique in order to improve sharpness between contrast media and organization. And sharpness and contrast was improved.

Development of New Value-added Corn Dog Using Milk Powder, Egg and Potato (분유, 계란 및 감자를 이용한 새로운 Value-added Com Dog 개발에 관한 연구)

  • Park Jin-Kwan;Kim Jin-Man;Lee Si-Kyung;Lee Chi-Ho
    • Food Science of Animal Resources
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    • v.26 no.2
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    • pp.236-240
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    • 2006
  • This study was conducted to manufacture new value-added corn dog using potato, milk powder and egg as nutritious and surplus agricultural and livestock products. A typical corn dog was manufactured with corn dog powder, potato, milk powder and egg as the same method of conventional corn dog. Corn dogs were divided into four groups; control group A [conventional corn dog], group B [corn dog manufactured with the fixed content of corn dog powder, milk powder, and egg, potato, water (3: 3: 1: 1: 2)], group C [corn dog manufactured with the fixed content of corn dog powder, milk powder, and egg, potato, water (3: 3: 2: 1: 2)], group D [corn dog manufactured with the fixed content of corn dog powder, milk powder, and egg, potato, water (3: 3: 1: 2: 2)], Viscosity of corn dog batter, pH of corn dog, rheology and sensory evaluation were measured. There were no significant differences for viscosity and pH between original corn dog and manufactured corn dog (p>0.05). However, hardness and brittleness of manufactured corn dog D were superior to the other groups (p<0.05). Also, manufactured corn dog D was superior to the other groups by the results of sensory evaluation. Therefore, these results suggest that it may be possible to manufacture new value-added corn dog which can help to stimulate the consumption of nutritious and surplus agriculture and livestock products.