• Journal of Yeungnam Medical Science
• /
• v.5 no.2
• /
• pp.9-24
• /
• 1988

• The Journal of the Korea Contents Association
• /
• v.9 no.3
• /
• pp.278-287
• /
• 2009

The study find out developmental factors of the liver diseases in 29,531 subject of the healthy adults who diagnosed by using ultrasound at healthcare centers located at 6 cities around the nation. The results are as follows. Based on the result of the study, the liver diseases diagnosed by using ultrasound revealed to show 43.1％ of prevalence, and the occurrence was significantly higher in male(23.3％) than in female (19.8％)(p<0.001). The disease revealed to show highest prevalence rate in regionally, Dae-jeon was found to record the highest prevalence by showing 49.6％ (p<0.001). The order of liver disease prevalence was the highest in Dae-jeon(49.6%),which was followed by Seoul(48.2%), Busan(42.9%), Incheon(36.2%), Daegu(36.2%), Kangju(32.1%)(p<0.001). The order of hepatic disease prevalence was the highest in fatty liver (69.7％), which was followed by intrahepatic cysts (13.2％), intrahepatic calcification (9.6％), intrahepatic hemangioma (4.5％), intrahepatic tumor (1.4％), diffuse liver disease (1.0％),and liver cirrhosis (0.5％) (p<0.001). The liver disease revealed to show highest prevalence rate in 40s and regionally, disease was found to record the highest prevalence from 30s to 50s (p<0.001). The distribution of the liver diseases by sex revealed to show the higher occurrence of the fatty liver and the diffuse liver diseases in male, but the intrahepatic cysts, intrahepatic calcification and intrahepatic tumors were highly distributed in female. In the regional evaluation, the fatty liver was most often found in Busan, and intrahepatic cysts, intrahepatic hemangioma, intrahepatic calcification and intrahepatic tumors were highly found in Dae-jeon and Seoul revealed to show higher occurrence of diffuse liver disease than other regions (p<0.001). The multiple regression analysis for the related factors which affect the prevalence of the liver diseases resulted to show the higher prevalence by age. sex,

• 대한한약
• /
• s.4
• /
• pp.300-301
• /
• 2000

• 간의등불
• /
• s.30
• /
• pp.10-11
• /
• 2003

• 간의등불
• /
• s.32
• /
• pp.18-19
• /
• 2003

• 간의등불
• /
• s.28
• /
• pp.24-25
• /
• 2002

• 간의등불
• /
• s.29
• /
• pp.4-7
• /
• 2003

• Journal of radiological science and technology
• /
• v.32 no.1
• /
• pp.79-86
• /
• 2009

The study found out developmental factors of the liver diseases in 29, 531 cases of the healthy adults who were diagnosed by using ultrasound at domestic healthcare centers in 6 cities. The results are as follows. Based on the result of the study, the liver diseases diagnosed by using ultrasound was revealed to show 43.1% of prevalence, and the occurrence was significantly higher in male (23.3%) than in female (19.8%). The prevalence of hepatic diseases related to the BMI was revealed to show highest prevalence of the fatty liver in obese group (BMI $\geqq$ 25) by recording 44.3%. Smoking contributed to the high prevalence of all liver diseases. Although the fatty liver was the most frequently occurred form of liver diseases by recording the prevalence of 49.1% (22.2% in male, 26.9% in female), the significant difference was found only in female (p < 0.05), but male group did not show significant difference (p > 0.05). The prevalence of hepatic diseases related to the hypertension was revealed to show highest prevalence of the fatty liver in hypertension group by recording 67.7%. The prevalence of hepatic diseases related to the diabetes was revealed to show highest prevalence of the fatty liver in diabetes group by recording 66.2%. The high prevalence of all hepatic diseases was related to diabetes mellitus with statistical significance (p < 0.001). The multiple regression analysis for the related factors which affect the prevalence of the liver diseases showed the higher prevalence by age. Sex, obesity and diabetes mellitus were positively related to the prevalence (p < 0.05) while hypertension and smoking showed no significant relationship to the prevalence of the disease (p > 0.05).

• Proceedings of the KIEE Conference
• /
• 1999.11c
• /
• pp.775-777
• /
• 1999

흉부 단순 X선 사진에 있어서 폐의 간질성 음영의 특징을 컴퓨터를 이용하여 해석하는 시스템을 구축하여 그 정확도를 검토하였다. 이 시스템에서는 X선 사진을 디지털화 해서 관심영역을 설정하여 4방향 라플라시안-가우시안 형상필터를 행하여 2치화 한후, 계속해서 선상음영 판정처리 및 선상음영 차분처리를 행해 간질성 음영의 특징을 나타내는 몇가지 물리적인 지표를 계산 하였다. 82명의 정상예와 이상예에 대하여 이들 물리적 지표의 ROC 해석을 행하여 간질성 폐질환 변화의 양호한 검출결과를 얻었다.

• 발명특허
• /
• v.31 no.4 s.358
• /
• pp.54-56
• /
• 2006

현재 병원 및 의원에서는 GOT, GPT 등의 간 질환 진단시약을 사용하고 있다. 하지만 이것들은 특이성이 떨어진다는 문제점을 가지고 있다. 또한 초기 염증 및 급성간염 진단에 있어서는 유용할 지 모르나 만성간염, 간경변, 간암에 있어서는 수치가 정상으로 나타나는 경우도 있어 오진 및 의료분쟁의 원인이 되기도 하 는 등의 치명적인 오류를 안고 있다. 이렇듯 간의 초기 염증 및 급성간염 진단만 가능하던 현재의 간질환 진단시약이 가지고 있는 문제점을 해결하여 만성간염, 간경변, 간암 등까지도 확실하게 구별할 수 있음은 물론 간질환의 진행상태까지도 판단할 수 있는 세계 유일의 제품을 개발하게 되었다. 이는 간경변, 간암의 경우 9 6 %의 높은 판정비율을 나타낸다.