• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.734-744
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• 2002

The purpose of this study was to evaluate the protective effect of Kamicheonggan-tang(KCGT) on pre-hepatocarcinogenesis induced by N-nitrosomorpholine. The studied using blood chemistry, lipidperoxidation, antioxidant, immunohistochemistry and morphological change. The results were obtained as follows. In the pre-hepatocarcinogenesis induced by NMP, serum AST, ALT, ALP and total bilirubin were not changed in NMP and NK treated group after 1 st week, but desreased in NK treated group after 4th week as compared with NMP treated 4th week group. The content of GSH was similary to in NK treated groups as compares with data of normal group. The content of MDA was increased in NK treated group after 1st and 4th week, and more increased in the NMP treated group than those of their NK treated group. The immunohistochemically, stain of GST-p, positive lesions of KCGT were significantly decreased than those of NMP treated group. The histopathologically, fat changes, nucleotic changes, oval cell and inflammatory cells in periportal were observed in NMP treated fater 4th week, but those were significantly decreased from 4th week in the NK treated group. And the enlarged nucleus was not changed in KCGT treated group, but increased in NMP treated group after 1st and 4th week. The ultrastructurally, nucleotic changes, glycogen degeneration, lipid droplet and rER fragmentation were observed in NMP treated group after 4th week, but those changes were significantly decreased from 4th week in the NK treated group. These results suggested that KCGT extracts has protective effect on prehepatocarcinogenesis by NMP, might be usefully applied for clinical treatment of hapatic disease and also it was necessary to do more studies about its mechanisms.

• The Journal of the Korea Contents Association
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• v.17 no.10
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• pp.667-685
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• 2017

The purpose of this study was to explore the meaning and essence of experience of family members as care-givers of terminally ill cancer patients at hospice wards. This study was based on the Giorgi phenomenological method, which describes the experiences about the family caregivers. We had in-depth interview with spouses and orthogonal families of nine terminally ill cancer patients. Results were drawn into 13 essential themes, 45 sub themes, and 122 main points. The essential themes are as follows: "cling of life", "bed-keeper", "sacrifice of care", "physical and mental exhaustion during care process","feeling of love and hatred", "avenge on a patient", "self-condemnation", "futility after exhaustion", "consolation of other caregivers", "utmost efforts in resignation", "freedom from suffering", "paradoxical blessing of cancer", "introspected revolution", and "preparation of a dignified death". Implications and limitations are discussed based on study results.

• The Journal of Korean Academic Society of Nursing Education
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• v.14 no.1
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• pp.127-137
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• 2008

Purpose: This study aimed to explore the level of importance perceived by caregivers of elderly on the education of long term care nursing assistants (LTCNAs) taking care of elders with dementia or stroke. Method: Data was collected from 296 participants (112 families, 98 NAs, and 86 RNs) from October 2006 to February 2007. A structured questionnaire was used for data collection. Result: The item of 'attitude while caring for the aged' was identified as most important. The family group reported that 'position change' and 'understanding of geriatric diseases' were the most important for education, while LTCNAs, highly identified, 'bathing', and 'bed sheet change'. The RNs group regarded 'position change', and 'bathing' as most important. Institutions demanding LTCNAs' activities were special facilities for elderly care and special hospitals for the aged, and the need was also high in families with an elder incapacitated by illness. Conclusion: Nurses need to take an interest in education for enhancing the quality of LTCNAs and thus advance the quality of nursing care as well as the quality of life for the aged.

• Clinical and Experimental Pediatrics
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• v.51 no.5
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• pp.538-541
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• 2008

Menkes disease is an X-linked recessive copper transport disorder characterized by neurological deterioration, connective-tissue damage, and abnormal hair growth. It is caused by the mutation of the ATP7A gene. This report describes a four-month-old boy with neurological symptoms typical of Menkes disease plus unusual liver involvement. He developed seizures at three months of age and exhibited hypotonia, cephalhematoma, a sagging face, redundant and hypopigmented skin, and abnormal hair growth. In addition, he had unexplained hepatomegaly and high hepatic transaminase. We confirmed the diagnosis of Menkes disease by mutation analysis of the ATP7A gene. To exclude other possible causes for the hepatic abnormalities, a liver biopsy was performed, revealing intracytoplasmic cholestasis, focal spotty necrosis, and minimal lobular activity. The patient's liver involvement may be an underestimated complication of Menkes disease.

• Journal of the Korean Society of Costume
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• v.57 no.1 s.110
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• pp.147-162
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• 2007

The purpose of this study is to grasp the inconvenience and problems with caregivers' uniforms and preferred designs by examining the wearing conditions of these uniforms in medical welfare facilities for the aged. To attain this purpose, a questionnaire was completed by direct observation and by interviewing caregivers in specialized hospitals for the aged and those engaged in nursing and then a preliminary examination was carried out. The questionnaire was given to 228 caregivers. Following are the results of this research. It was found that the caregivers in medical welfare facilities for the aged were women in their 50s, wearing primarily a size 77 uniform. It was revealed that when the caregivers bathe patients, they usually get wet from the knees to the bottom part of their pants and many of them (61.2%) change both their tops and pants after giving a bath. The caregivers said that every part of the tops of existing uniforms, except the armpits, were a little large or too long. It turned out that the area of the armpits, the front buttons, crotch, hip area, and knees are mostly the areas that readily wear out in the uniforms. It was reported that the uncomfortable parts in the uniforms a.e the armpits, shoulders, and the front adjusting parts of the tops and the hips, thighs, and the crotches of the pants. The material for the uniforms have problems in ventilation, fluffing, absorption of sweat, and permeation of odor.

• Journal of muscle and joint health
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• v.26 no.3
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• pp.241-250
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• 2019

Purpose: This study was conducted to identify influencing factors on the performance of healthcare-associated infection control and microbiological hand contamination among caregivers at a tertiary hospital. Methods: The participants of this study were 59 caregivers woring at a tertiary hospital. Data were collected from July 1 to 30, 2018. Data were analyzed using descriptive statistics, t-test, ANOVA, Scheffé test, Pearson's correlation coefficients and stepwise multiple regression by SPSS 23.0 Win program. Results: Multiple regression analysis revealed that factors influencing performance of healthcare-associated infection control were awareness (β=.63, p<.001) and the experience of infection-related education (β=-3.40, p=.042). Regression equations describing the performance of healthcare-related infection control were found to be appropriate (F=27.29, p<.001) and accounted for 68% of variance. Factors affecting the degree of microbiological hand contamination were work experience (β=-0.28, p=.026) and healthcare-related infection performance (β=-0.28, p=.029). A regression equation describing the microbiological hand contamination was appropriate (F=6.10, p=.004) and accounted for 42% of variance. Conclusion: The findings of this study suggest that it is necessary to increase performance of healthcare-associated infection control by caregivers. Also, educations for preventing healthcare-associated infection and guidelines for increasing compliance with healthcare-associated infection control are recommended to improve performance of healthcare-associated infection control.

• KIPS Transactions on Software and Data Engineering
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• v.9 no.2
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• pp.69-76
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• 2020

In this paper, we introduce a method to visualize the contrast diffusion patterns and the dynamic vascular patterns in a contrast-enhanced ultrasound image sequence. We present an imaging technique to visualize parameters such as contrast arrival time, peak intensity time, and contrast decay time in contrast-enhanced ultrasound data. The contrast flow pattern and its velocity are important for characterizing focal liver lesions. We propose a method for representing the contrast diffusion patterns as an image. In the methods, respiratory motion may degrade the accuracy of the parametric images. Therefore, we present a respiratory motion tracking technique that uses dynamic weights and a momentum factor with respect to the respiration cycle. Through the experiment using 72 CEUS data sets, we show that the proposed method makes it possible to overcome the limitation of analysis by the naked eye and improves the reliability of the parametric images by compensating for respiratory motion in contrast-enhanced ultrasonography.

• The Journal of Internal Korean Medicine
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• v.27 no.4
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• pp.962-968
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• 2006

Background : Liver cirrhosis is a disease of the liver in which normal cells are replaced by scar tissue. This condition results in the failure of the liver to perform many of its usual functions. Liver cirrhosis includes ascites, jaundice, portal hypertension, varices etc. Objectives : This study was to see if there is a decrease in ascites of liver cirrhosis to under acupuncture and herbal treatment to test their validity. Methods : Measuring the response to treatment of ascites by giving pyengwie-san hap wieryungtang gamibang and treating the patient with acupuncture, these clinical symptoms were observed: weight, abdominal circumference, abdominal SONO, chest X-ray, and lab findings. Results : Over 18 days the daily average loss of weight and abdominal circumference 0.43kg and 0.56cm, respectively. Lab findings of liver functions showed improvement. Conclusions : This report shows a role for acupuncture and herbal treatment for treating ascites in liver cirrhosis.

• Health Policy and Management
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• v.29 no.4
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• pp.502-512
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• 2019

Background: The purpose of this study was to identify role ambiguity of comprehensive nursing care unit nurses. Methods: A concept analysis method by Walker and Avant was used to understand role ambiguity of comprehensive nursing care unit nurses. Results: The antecedents of role ambiguity of nurses at comprehensive nursing units were shortage of nurses, unclear admission criteria, and demands for customized nursing care according to severity. Attributes include ambiguity in role delegation, patient placement ambiguity, and professional ambiguity among nursing staff. The consequences were diminished job satisfaction due to excessive workload, difficulty in resolving role ambiguity due to the lack of work analysis studies, and poor outcome of nursing indicators. Conclusion: Improvement of nationwide awareness for comprehensive nursing care unit is required. Clear division at scope of practice for nursing staff in accordance of each medical institution's characteristics is essential. Nurses at comprehensive nursing care unit should understand nature of role ambiguity that occurs as they work in large groups. Nurses should promote communications between nursing staff and they must have volition to improve status quo. An additional research of comprehensive nursing care on the causes of role ambiguity in the practice of nursing care for ward nurses is needed, and management measures should be sought at the organizational level.

• The Journal of the Korea Contents Association
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• v.10 no.10
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• pp.304-317
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• 2010

The purpose of this study is to research on attitudes toward legalization of death with dignity. The respondents are 561 adults aged 20 years old and over, living in Seoul and Kyunggi Province. Research questionnaire consist of 28 questions concerning general background, personal experiences of death, attitudes toward death, pros and cons on death with dignity and legalization. Statistical analyses employ frequency, mean, cross tab, and t-test. 87.3% of respondents agree the legalization of death with dignity. The persons who are older, self-employed, and production employees, get married, live with spouse, believe buddhism, experience care for the death, believe life after death, recognize the necessity of testament agree more on death with dignity. The first requisite for legalization of death with dignity is the standard of judgement concerning self decision on death with dignity. The decision makers are prioritized by self, family member in order. The necessary services for decisions on death with dignity are the mediation role between medical team and family, medical information about illness prognosis and prolongation, psychological counselling on depression.