• Journal of Life Science
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• v.30 no.9
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• pp.791-797
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• 2020

Maqui berry are known as one of the "superfoods" and can purportedly improve health. The effects of orally administered maqui berry extract on biological parameters such as serum lipids and blood cells in healthy subjects were investigated in rats in vivo for 2 weeks. Possible causes of harmful effects on liver and kidney function were also examined. After oral administration of maqui berry extract, levels of serum triglyceride (TG) were decreased to almost 30% less from the control, and high density lipoprotein cholesterol (HDL-C) was increased to 18% more; thus, serum lipids profile seemed to be improved. The administration of maqui berry extract increased red blood cell concentration by 10% from the control, while both the hemoglobin and the mean corpuscular volume (MCV) were increased by 12%. Maqui berry extract also increased the concentration of serum total proteins by 30% of the control and that suggests protein metabolism might be improved. Moreover, maqui berry decreased serum levels of glutamin oxaloacetate transaminase (GOT) and glutamin pyruvate transaminase (GPT) by 12% from the control group so maqui berry improved liver function. This study suggests that oral administration of maqui berry extract may be helpful to improve those heath parameters like serum lipids profile, red blood cell level, liver protection. It would also be very useful for the development of high value products such as functional foods and pharmaceutics in the future.

• Journal of Nutrition and Health
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• v.20 no.6
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• pp.432-441
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• 1987

This study was undertaken to investigate effects of alcohol and fat content in a balanced diet on growth, hepatic function and some biochemical indices of blood in growing rats. Fourty eight male rats of Sprague-Dawley strain weighing about 160g were divided into 4 groups ; high fat diet group, alcohol-adminstered high fat diet group, low fat diet group and alcohol-administered low fat diet group. High and low fat diet supplied 30% and 12%, respectively, of total calorie intake from fat and alcohol-treated groups received water containing 10% ethanol. Diets contained adequate amounts of all nutrients required for rats, including lipotropic agents(choline and methionine) to minimize effects of factors other than alcohol on liver function. Growth rate was lowest in alcohol-administered low-fat diet group, despite that their energy intake was equivalent to the others. For a 3-week study period, 21.86% and 23.61% of total calorie intake were derived from alcohol in alcohol-adminitered high fat diet group and low fat diet group, respectively. There was no influenced on vitamin B$_1$ status by alcohol consumption. Concentration of triglyceride in plasma increased with alcohol comsumption, and the effect was greater after 6 weeks than after 3 weeks of alcohol consumption . Difference of dietary fat content did not affect the level of triglyceride . The levels of total cholesterol and HDL-cholesterol in plasma were not influenced by alcohol consumption. Serum glutamate pyruvate transaminase activity and hepatic mitochondrial respiration rate did not differ between groups. The results indicate that neither moderate alcohol drinking for 6 weeks nor fat content with a balanced diet caused any dramatic change of metabolism and liver function in rats. However they suggest that even moderate alcohol consumption can affect growth of animals dramatically and the effect may be lessened with relatively high fat content in diet.

• Journal of radiological science and technology
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• v.29 no.1
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• pp.7-11
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• 2006

This study obtained the following conclusions by making a comparative study on fatty liver diagnosed by abdominal ultrasonography and clinical laboratory findings. I surveyed the value of abdominal ultrasound in 400 patients without clinical symptoms at C Health Clinic Center, Seoul. 1. Compare with blood pressure was high(systolic/diastolic) in 7.5%/4.5% on persons who were diagnosed fatty liver. 2. At the time of the diagnosis, Total cholesterol level was increased in fatty liver patients, HDL-cholesterol level was high in fatty liver patients. And Trigryceride level was increased in fatty liver persons, LDL-cholesterol was high in fatty liver persons. 3. SGOT level was increased in 5.5% on patients who were diagnosed fatty liver, 0% on persons who were normal and SGPT level was high in 29.5% on people who were diagnosed fatty liver, 0% on patients who were diagnosed normal.

• Research in Community and Public Health Nursing
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• v.19 no.2
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• pp.234-246
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• 2008

Purpose: This study was performed in order to examine the effects of an smoking cessation counselling program for smoking cessation success. Method: Among a total of 468 persons who had ceased from smoking for 6-months and had visited the smoking cessation clinic of a public health center from January 2nd to December 31th in 2006, 61 in all who had a negative reaction in the urine nicotine check were selected for this study. Collected data were expiratory CO concentration, BMI, blood pressure, liver function, and lipid metabolism. These data were analyzed by descriptive statistics, repeated measured ANOVA and paired t-test with the SPSS/PC(Version 12.0) program. Result: There were significant changes in expiratory CO concentration, SBP, DBP, AST, ALT, and TG, but not in BMI, $\gamma$-GTP, TC, HDL-C, and LDL-C. Conclusion: This study showed that smoking cessation through a smoking cessation counselling program has partially positive effects for smoking cessation success. The results of this study show that the smoking cessation counselling program at the smoking cessation clinic of a public health center should be continued for smoking cessation success.

• Journal of the Korean Society of Food Science and Nutrition
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• v.22 no.2
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• pp.144-148
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• 1993

The present study was undertaken to compare the pharmacological activities of crude Lithospermi radix reported with the clinical uses in the oriental medicine. Crude Lithospermi radix uesd for the treatment of burn, eczema, blister, diuretic, scarlet fever and septicemia as antipyretic, antidotic and antiphlogistics. Therefore we tested the effects of Lithospermi radix water extract on the liver-protective activities in the rats. The results obtained from enzyme assay, measurement of serum and liver alanine. aspartate aminotransferase(ALT, AST) and lipid composition indicated that Lithospermi radix water extract showed significant liver-protective activities against benzo(a)pyrene-induced hepatotoxicity.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.468-470
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• 2001

Chitosan-alginate capsules were formed by the electrostatic interactions and had appropriate mechanical strength, permeability to albumin and stability to hepatocyte. Pig hepatocytes were isolated and immobilized in chitosan-alginate capsules. Encapsulation in 3 minutes and spheroid formation period of 24 hours were optimum condition for the high liver function. Pig hepatocytes density of $90.{\times}10^6$ cells/mL in capsules was suitable for the application to bioartificial liver support system.

• 건강소식
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• v.14 no.8 s.141
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• pp.2-5
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• 1990

3무의 섬 울릉도, 유난히 부유해 보이지 않으면서 그렇게 부족해 보이지 않는 섬 울릉도, 그곳에서, 더욱 날씨에도 불구하고 울릉도내 학생건강검사와 부녀자 무료건강검사를 위해 건협 경북지부는 지난 7월 9일부터 4일간을 분주히 뛰어 다녔다. 짧은 검진 일정 동안 학생 심전도, 빈혈, 간염검사, 부녀자 간기능, 간염, 자궁암, 심전도 검사 등을 위해 식사까지 거르면서 울릉도 곳곳을 누비는 건협 검진팀의 일정에 참여하면서 이번 두 검진 사업의 의의와 주민들의 반응을 들어봤다.(이본 호에서는 학생 건강검진 사업을 소개하며, 다음호에 부녀자 건강 검진 사업에 대해 소개합니다.)

• 대한예방의학회:학술대회논문집
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• 1999.10a
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• pp.44-44
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• 1999

• 대한예방의학회:학술대회논문집
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• 1999.10a
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• pp.330-331
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• 1999

• The Monthly Diabetes
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• s.220
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• pp.12-13
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• 2008

간은 체내에서 영양소의 합성, 분해, 저장, 운반, 대사산물의 처리 능력을 가지고 있어 '인체 내의 거대한 화학공장'이라고도 한다. 인슐린과 글루카곤은 에너지 대사 조절에 관여하는 호르몬으로 간 내에서 당의 대사에 도움을 준다. 하지만 이 호르몬들의 정상적인 대사는 인슐린저항성과 제 2형 당뇨병에 의해 방해를 받게 된다. 따라서 간수치가 높아 간질환이 동반되는 당뇨병의 경우에는 혈당조절에 더욱 어려움이 있다. 간기능 향상에 도움을 주며 혈당도 조절을 잘 하기 위해 어떻게 식사를 해야 하는지 알아보자.