• 한국의류산업학회지
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• 제16권3호
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• pp.476-484
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• 2014

The purpose of this study was to investigate the dyeing properties and anti-microbial ability of silk and wool fabrics dyed with Terminalia chebula Retzius(TCR) extract using two extraction solvent, hot water and methanol. Dyeing properties of fabrics were studied by investigating the characteristics of colorant, changes in dye uptake under different dyeing conditions, and by investigating color change when mordants were applied. Also, color fastness, and antimicrobial activity of dyed fabrics were estimated. Regardless of extraction solvent type, colorant showed maximum absorption wavelength at 280 nm and 578 nm, which implied that tannin was the major pigment component of TCR. Also, through FT-IR spectrum result, it was confirmed that tannin of TCR methanol extract was hydrolysable tannin. But for the hot water extract, it was only assumed that its tannin was condenced tannin. Fabric dyed with hot water solvent extract showed higher dye uptake than fabric dyed with methanol solvent extract, dye uptake increasing by higher concentration of the dye, longer dyeing time and higher dyeing temperature. And the absorption curve between TCR extract and protein fiber was shaped in the form of Langmuir adsorption isotherm. Fabric dyed without mordant was yellow in color, and when dyed with mordant, fabric showed various colors depending on mordant types except Sn. Color fastness to washing was generally fine and color fastness to light was moderate. But color fastness to rubbing and dry cleaning was outstanding. Lastly, dyed fabrics showed very good antimicrobial activity of 99.9% against Staphylococcus aureus and Kiebsiella pneumoniae.

• 한국의류학회지
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• 제38권3호
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• pp.415-426
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• 2014

This study investigated the color change, enhancement of dye uptake, washing fastness, and light fastness of cotton and silk when dyed with Juniperus chinensis and Terminalia chebula (combination dyeing) using various methods. The dyeing methods were 1) dyeing Juniperus chinensis extract and Terminalia chebula Retzius extract sequentially (J-T), 2) dyeing Terminalia chebula Retzius extract and Juniperus chinensis extract sequentially (T-J), 3) dyeing Juniperus chinensis extract and Terminalia chebula Retzius extract simultaneously (J+T), and 4) dyeing Juniperus chinensis extract 4 times repeatedly and followed by a dyeing Terminalia chebula Retzius extract in sequence. In terms of increased dyeing uptake, combination dyeing (dyeing 2 times like method 1, 2, 3) had the same impact as the repeated dyeing (method 4). The color of J, T combination dyeing showed wide range of mixed YR series, Y series resulting from Terminalia chebula Retzius, and R series resulting from Juniperus chinensis. In cotton, J-T dyeing method showed superior enhancement of dye uptake, and T-J method in silk. In both of the cases, Y series color from Terminalia chebula Retzius extract was mainly shown (Y series color was superior to R series color after dyeing). Therefore, it is recommended for cotton to implement T-J method and for silk to implement J-T method in order to enhance both dyeing uptake and emphasize the color of R series. The K/S value of combination dyed fabrics was decreased by increasing washing time; however, the K/S value of combination dyed fabrics was increased by increasing UV irradiation time. But after repeated washing and longer UV irradiation, ${\Delta}E$ value of combination dyed fabric became smaller compared to fabric dyed with Juniperus chinensis only. Thus, it was found that after J, T combination dyeing, fabric became less prone to fading by washing and UV than after Juniperus chinensis single dyeing was done.

• 한국식품영양과학회지
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• 제42권10호
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• pp.1539-1543
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• 2013

본 연구에서는 Terminalia chebula Retz.의 성숙열매인 가자 메탄올 추출물(TCME)을 이용하여 HAT 활성을 억제함으로써 AR의 아세틸화 감소를 유도하여 전립선암세포의 성장을 억제하였다. TCME의 처리는 HAT 활성을 100 ${\mu}g/mL$의 농도에서 50% 이상 저해하였으며, p300과 CBP 등의 특이적 HAT 단백질에서도 유의적인 저해활성을 보였다. TCME를 0~100 ${\mu}g/mL$로 안드로젠 수용체 의존적 전립선 암세포인 LNCaP에 처리한 결과, reporter assay에서 AR 매개 전사를 억제하고 AR target gene의 mRNA 발현을 억제하였다. 동일 농도에서 AR의 아세틸화가 감소한 결과를 보였으며, 결국 전립선암세포주의 성장억제를 유도하였다. 이같은 결과에서 가자 메탄올 추출물은 HAT 활성을 억제하며, AR의 아세틸화를 감소시킴으로써 효과적인 전립선암 치료소재로 개발될 수 있는 가능성이 있음을 제안한다.

• Journal of Applied Biological Chemistry
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• 제55권4호
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• pp.217-220
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• 2012

오가피(Acanthopanax sessiliflorus Seeman) 열매를 실온에서 70% ethanol (EtOH)로 추출하고 이 추출물을 ethyl acetate (EtOAc) 분획, n-butyl alcohol 분획, $H_2O$ 분획으로 나누었다. EtOAc 분획에 대하여 silica gel, octadecyl silica gel 및 Sephadex LH-20 column chromatography를 반복 실시하여 2종의 화합물을 분리, 정제하였다. NMR, infrared spectroscopy, 및 electron ionization/mass spectrometry 등의 spectrum을 해석하여, 화합물 1과 화합물 2를 각각 3,5-dihydroxycinnamic acid과 protocatechuic acid 로 구조를 결정하였다. 화합물 1은 오가자에서는 처음으로 분리된 화합물이다. 또한 이 화합물에 대한 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)diammonium salt, 1,1-diphenyl-2-picrylhydrazyl 및 oxygen radical absorbance capacity radical 소거능을 이용한 항산화 활성을 측정하였는데, 모두 vitamin C보다 2배 이상 활성이 높은 것으로 나타났다.