• Title/Summary/Keyword: 가상환자

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Dosimetric Comparison of Left-sided Whole Breast Irradiation using a Virtual Bolus with VMAT and static IMRT (좌측 유방의 세기변조 방사선치료 시 Virtual Bolus 적용에 따른 선량 변화 비교 평가)

  • Lim, Kyeong Jin;Kim, Tae Woan;Jang, Yo Jong;Yang, Jin Ho;Lee, Seong Hyeon;Yeom, Du Seok;Kim, Seon Yeong
    • The Journal of Korean Society for Radiation Therapy
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    • v.31 no.2
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    • pp.51-63
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    • 2019
  • Purpose: Radiation therapy for breast cancer should consider the change in breast shape due to breathing and swelling. In this study, we evaluate the benefit of using virtual bolus for IMRT of left breast cancer. Materials and methods: 10 patients with early breast cancer who received radiation therapy after breastconserving surgery compared the VMAT and IMRT plans using the virtual bolus method and without using it. The first analysis compared the V95%, HI, CI of treatment volume, Dmean, V5, V20, V30 of ipsilateral lung, and Dmean of heart in VMAT plan made using the virtual bolus method(VMAT_VB) to the plan without using it(VMAT_NoVB) in case there is no change in the breast. In IMRT, the same method was used. The second analysis compared TCP and NTCP based on each treatment plan in case there is 1cm expansion of treatment volume. Result: If there is no change in breast, V95% in VB Plan(VMAT_VB, IMRT_VB) and NoVB Plan(VMAT_NoVB, IMRT_NoVB) is all over 99% on each treatment plan. V95% in VMAT_NoVB and VMAT_VB is 99.80±0.17% and 99.75±0.12%, V95% in IMRT_NoVB and IMRT_VB is 99.67±0.26% and 99.51±0.15%. Difference of HI, CI is within 3%. OAR dose in VB plan is a little high than NoVB plan, and did not exceed guidelines. If there is 1cm change in breast, VMAT_NoVB and IMRT_NoVB are less effective for treatment. But VMAT_VB and IMRT_VB continue similar treatment effect compared in case no variation of breast. Conclusion: This study confirms the benefit of using a virtual bolus during VMAT and IMRT to compensate potential breast shape modification.

Limited Lateral Retinacular Release for Treatment of Painful Bipartite Patella (통증이 있는 이분슬개골의 제한적인 외측 지대 유리술 치료)

  • Yi Seung Rim;Hahn Sung Ho;Yang Bo Kyu;Chung Shun Wook;Ha Jung Hyun;Ahn Young Joon;Chung Byung June;Jeon Do Hwan;Bin Sung Woo
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.3 no.1
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    • pp.60-65
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    • 2004
  • Purpose: The purpose of this study was to evaluate the results of limited vastus lateralis release for treatment of painful bipartite patella. Materials and Methods: From Jan. 1995 to Jun. 2002, we performed limited lateral retinacular release in 14 patients(16 cases) for treatment of painful bipartite patella. All patients were men and mean age was 22.3 years old. The opeative techique was that insertion of the vastus lateralis to the painful patellar fragment is detached subperiosteally. We evaluated the clinical results by degree of pain and level of activity. Also we analyzed the radiologic findings by measuring fragment tilting angle and gap between fragments. The mean follow up period was 14 months. Results: At final follow up, all of the patients showed pain relief and can be returned to more than recreational sports activity after the operation. On radiologic findings, fragment tilting angle and gap between fragments were reduced at statistically significant level. Conclusion: The limited lateral retinacular release for treatment of painful bipartite patella is one of good methods which is less invasive and shows good results in clinical and radiologic findings.

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Analysis of Intervention in Activities of Daily Living for Stroke Patients in Korea: Focusing on Single-Subject Research Design (국내 뇌졸중 환자를 대상으로 한 일상생활활동 중재 연구 분석: 단일대상연구 설계를 중심으로)

  • Sung, Ji-Young;Choi, Yoo-Im
    • Therapeutic Science for Rehabilitation
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    • v.13 no.1
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    • pp.9-21
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    • 2024
  • Objective : The purpose of this study was to confirm the characteristics and quality of a single-subject research that conducted interventions to improve activities of daily living (ADL) in stroke patients. Methods : 'Stroke,' 'activities of daily living,' and 'single-subject studies' were searched as keywords among papers published in the last 15 years between 2009 and 2023 among Research Information Sharing Service, DBpia, and e-articles. A total of nine papers were examined for the characteristics and quality before analysis. Results : The independent variables applied to improve ADL included constraint-induced therapy, mental practice for performing functional activities, virtual reality-based task training, subjective postural vertical training without visual feedback, bilateral upper limb movement, core stability training program, traditional occupational therapy and neurocognitive rehabilitation, smooth pursuit eye movement, neck muscle vibration, and occupation-based community rehabilitation. Assessment of Motor and Process Skills was the most common evaluation tool for measuring dependent variables, with four articles, and Modified Barthel Index and Canadian Occupational Performance Measure were two articles each. As a result of confirming the qualitative level of the analyzed papers, out of a total of nine studies, seven studies were at a high level, two at a moderate level, and none were at a low level. Conclusion : Various types of rehabilitation treatments have been actively applied as intervention methods to improve the daily life activities of stroke patients; the quality level of single-subject studies applying ADL interventions was reliable.

Evaluation of Planning Dose Accuracy in Case of Radiation Treatment on Inhomogeneous Organ Structure (불균질부 방사선치료 시 계획 선량의 정확성 평가)

  • Kim, Chan Yong;Lee, Jae Hee;Kwak, Yong Kook;Ha, Min Yong
    • The Journal of Korean Society for Radiation Therapy
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    • v.25 no.2
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    • pp.137-143
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    • 2013
  • Purpose: We are to find out the difference of calculated dose of treatment planning system (TPS) and measured dose in case of inhomogeneous organ structure. Materials and Methods: Inhomogeneous phantom is made with solid water phantom and cork plate. CT image of inhomogeneous phantom is acquired. Treatment plan is made with TPS (Pinnacle3 9.2. Royal Philips Electronics, Netherlands) and calculated dose of point of interest is acquired. Treatment plan was delivered in the inhomogeneous phantom by ARTISTE (Siemens AG, Germany) measured dose of each point of interest is obtained with Gafchromic EBT2 film (International Specialty Products, US) in the gap between solid water phantom or cork plate. To simulate lung cancer radiation treatment, artificial tumor target of paraffin is inserted in the cork volume of inhomogeneous phantom. Calculated dose and measured dose are acquired as above. Results: In case of inhomogeneous phantom experiment, dose difference of calculated dose and measured dose is about -8.5% at solid water phantom-cork gap and about -7% lower in measured dose at cork-solid water phantom gap. In case of inhomogeneous phantom inserted paraffin target experiment, dose difference is about 5% lower in measured dose at cork-paraffin gap. There is no significant difference at same material gap in both experiments. Conclusion: Radiation dose at the gap between two organs with different electron density is significantly lower than calculated dose with TPS. Therefore, we must be aware of dose calculation error in TPS and great care is suggested in case of radiation treatment planning on inhomogeneous organ structure.

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Accuracy of the healing abutment and impression coping combined system on implant impression (인상채득이 가능한 치유지대주를 이용한 임플란트 인상채득의 정확성)

  • Jeon, Kyoung-Bae;Lee, Du-Hyeong;Kim, Jung-Han;Hwang, Jun-Ho;Park, Hyun-We;Lee, Kyu-Bok
    • The Journal of Korean Academy of Prosthodontics
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    • v.53 no.2
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    • pp.105-110
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    • 2015
  • Purpose: The purpose of this study was to evaluate the 3 dimensional accuracy of impression taking on the newly developed healing abutment and impression coping combined system comparing conventional pick-up type impression. Materials and methods: For 10 patients who had a single missing tooth on molar area, dental implants (SuperLine; Dentium, Seoul, Korea) were placed and healing abutment (MyHealing; Raphabio Co., Seoul, Korea) abutments were connected. After 3 months, transfer type impression with MyHealing and pick-up type impression with impression coping were performed twice in the same patients, and master models were fabricated. Customized prosthetic abutments (Myplant; Raphabio Co., Seoul, Korea) were milled and connected to the master casts. Through a dental scanner (Scanner S600; Zirkonzahn, South Tyrol, Italy), the master casts were converted into virtual casts. The length and angulation differences between casts were measured using 3 dimentional analysis program (Geomagic Qualify 12; Geomagic, Morrisville, NC, USA). Statistical significance was calculated using Kruskal Wallis test and Mann-Whitney U test (${\alpha}$=.05). Results: The length differences between the two systems were 0.032 mm in sagittal plane, and 0.029 in coronal plane, and 0.023 mm in horizontal plane. The angulation differences were $0.755^{\circ}$ in sagittal plane, and $1.275^{\circ}$ in coronal plane, and $0.420^{\circ}$ in horizontal plane. Conclusion: The accuracy of newly developed healing abutment system is similar to that of conventional pick-up impression. The new system can reduces chair time by not using separate impression coping.

Evaluation of surface dose comparison by treatment equipment (치료 장비 별 표면 선량 비교평가)

  • Choi Eun Ha;Yoon Bo Reum;Park Byoung Suk;An Ye Chan;Park Myoung Hwan;Park Yong Chul
    • The Journal of Korean Society for Radiation Therapy
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    • v.34
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    • pp.31-42
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    • 2022
  • Purpose: This study measures and compares the surface dose values in the virtual target volume using Tomotherapy, Halcyon, and TrueBeam equipment using 6MV-Flattening Filter-Free(FFF) energy. Materials and Methods: CT scan was performed under three conditions of without bolus, 0.5 cm bolus, and 1 cm bolus using an IMRT phantom (IBA, Germany). The Planning Target Volume (PTV) was set at the virtual target depth, and the treatment plan was established at 200 cGy at a time. For surface dosimetry, the Gafchromic EBT3 film was placed in the same section as the treatment planning system and repeated measurements were performed 10 times and then analyzed. Result: As a result of measuring the surface dose for each equipment, without, 0.5 cm, 1 cm bolus is in this order, and the result of Tomotherapy is 115.2±2.0 cGy, 194.4±3.3 cGy, 200.7±2.9 cGy, The result in Halcyon was 104.7±3.0 cGy, 180.1±10.8 cGy, 187.0±10.1 cGy, and the result in TrueBeam was 92.4±3.2 cGy, 148.6±5.7 cGy, 155.8±6.1 cGy, In all three conditions, the same as the treatment planning system, Tomotherapy, Halcyon, TreuBeam was measured highly in that order. Conclusion: Higher surface doses were measured in Tomotherapy and Halcyon compared to TrueBeam equipment. If the characteristics of each equipment are considered according to the treatment site and treatment purpose, it is expected that the treatment efficiency of the patient will increase as well as the treatment satisfaction of the patient.

Ethics for Cloned Human Beings: (<네버렛미고>를 통해본 복제 인간 윤리)

  • Kim, Mihye
    • The Journal of the Korea Contents Association
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    • v.17 no.8
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    • pp.121-129
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    • 2017
  • The evolution of biotechnology is no longer strange to the hypothetical scenario of cloning human genes to make cloned human beings. The characters of are cloned humans made in the laboratory by the 100-year-old life planning. They are cohabited in a school called Hailsham, where they are secretly reared. The purpose of this project is to provide healthy organs to real human patients with incurable diseases. The main characters Cathy, Tommy, and Ruth experience the growth of body and consciousness here during adolescence, and they also know the secret of identity as a clone. As adults, they move to a second residence, Cottage and are ready to begin organ donation. The second stage is also part of a program to provide more genuine-like organs to real patients. Even though they know all the plans that humans have built, they do not resist them and fatefully accept their situation. However, their non-responsiveness is not a declaration of renunciation of life, but a self-sacrificing life extension for another future that is the extension of life through their organ donation. The film emphasizes the fraternity and sacrificial attitudes of the cloned human beings and shows that it is necessary to continue the discussions on cloned human beings from a bio-ethical point of view supported by philosophical reasons.

두경부암의 6MV 광자선 치료 시 표면선량 증가를 위한 Spoiler의 유용성 평가

  • 이강혁;김원택;이화중;김대영
    • The Journal of Korean Society for Radiation Therapy
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    • v.14 no.1
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    • pp.41-47
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    • 2002
  • 1.목적 두경부암(head and neck Ca)과 쇄골상부(Supraclavicular)에 6MV 광자선으로 치료 시 치료부위(Target volume)가 피부에서 대략 $1^{\sim}2mm$정도 깊이에 위치할 경우, 6MV 광자선의 선량분포는 표면선량이 낮아서 치료에 적합하지 않기 때문에 Bolus와 같이 사용하지만 Skin Sparing(피부보호)효과의 손실로 피부의 손상이 발생할 수 있다. 이러한 이유로 피부의 보호와 치료 시 표면선량의 증가를 위해 Spoiler(산란판)를 제작하여 측정 후 그 특성을 이해하고 선량의 분포를 통하여 Bolus와 비교한 후에 Spoiler의 유용성에 대해 평가하고자 하였다. 2.방법 Siemens사 선형가속기(PRIMUS)의 6MV 광자선을 사용하여 Spoiler의 사용여부 및 Spoiler의 사용 시에는 조사면의 크기를 $5{\times}5,\;7{\times}7,\;10{\times}10,\;15{\times}15,\;20{\times}20cm^2$로 하고 Spoiler와 표면과의 거리는 6, 10, 15cm로 바꾸어 가면서 물팬톰(PTW. 독일)을 이용해 깊이와 측방에 따른 선량분포를 Markus 전리함(PTW. 독일)으로 측정하였으며 전리함의 방수를 위해 씌어진 방수 캡 때문에 표면선량을 별도의 고형 팬톰으로 측정하였다. 표면의 측정선량은 전리함의 측면 벽 등에 의한 선량 측정치의 증가 현상으로 과 반응을 보였으며 이를 교정하였다. 그리고 측정된 데이터를 치료계획 시스템(Pinnacle 6.0m)으로 비교, 분석하였다. 3.결과 Spoiler의 사용 시 3cm깊이 측정선량 백분율과 Spoiler를 사용하지 않은 해당 치료 조사면의 3cm깊이 선량의 백분율에 일치하도록 하여 가상의 치료 깊이인 2mm에서 측정값을 비교하여 본 결과 조사면 $5{\times}5,\;10{\times}10,\;20{\times}20cm^2$에서 OPEN시 62, 64, $70\%$, Bolus는 97, 97, $99\%$로 Spoiler의 사용 시 표면과의 거리가 6cm에서 82, 98, $103\%$, 10cm에는 72, 89, $101\%$, 15m에 65, 79, $96\%$로 나타났으며 표면에서의 측정값을 비교하여 본 결과 OPEN시 11, 17, $27\%$, Bolus는 84, 84, $86\%$, Spoiler의 사용 시 6cm에서 40, 71, $93\%$, 10cm에는 25, 50, $81\%$, 15cm에 18, 36, $67\%$를 나타내었다. 또한 3m깊이에서의 측방 선량분포에서 Spoiler의 거리변화(6, 10cm)는 심부선량의 변화에 영향을 주지 않는 것으로 확인할 수 있었다. 그리고 위의 실험측정치를 치료계획 시스템에 입력하여 선량분포를 확인한 결과 Spoiler를 사용하는 경우 OPEN에 비해 선량분포 영역을 표면으로 끌어 올릴 수 있으며 Bolus 보다 피부 보호효과는 어느 정도 유지가 되는 것을 보여주었다. 4.결론 이와 같이 Spoiler는 Bolus와 비교하여 6MV 광자선의 build up 영역을 표면으로 증가시키는 동시에 Skin Sparing(피부보호)효과를 유지할 수 있으며 두경부암의 치료에서 Spoiler의 사용이 가능한 조건으로는 조사면이 $5{\times}5cm^2$에서 Spoiler와 표면과의 거리가 6cm일 때, $7{\times}7cm^2$에서 6cm, 10cm였고 $10{\times}10cm^2$는 10cm, 15cm로, $15{\times}15cm^2$는 15cm의 간격으로 평가되었다. 또한 $20{\times}20cm^2$의 조사면, Spoiler가 6cm 간격 인 경우 Bolus를 사용한 것 보다 더욱 높은 표면선량을 나타내었다. 그러나 Spoiler와 표면간의 거리를 다르게 함으로써 깊이에 따라 선량분포를 다양하게 나타낼 수 있기 때문에 표면선량의 증가와 피부의 보호를 위해 환자의 피부 두께, 실제 치료 부위의 깊이 등을 고려한다면 Spoiler를 사용하는 것이 bolus를 사용하는 것보다 더 유용하게 적용할 수 있을 것으로 사료된다.

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Optimal Radiation Port Arrangements for Hepatic Tumor using 3-dimensional Conformal Radiotherapy Planning (3차원입체조형방사선치료 계획 시 간종괴의 위치에 따른 최적 조사 방향의 결정)

  • Lee, Ik-Jae;Seong, Jin-Sil;Shim, Su-Jung;Jeong, Kyoung-Keun;Cho, Kwang-Hwan
    • Journal of Radiation Protection and Research
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    • v.31 no.4
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    • pp.187-195
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    • 2006
  • The purpose of this study was to investigate the optimal beam arrangements for hepatic tumors, according to the location of the hepatic tumor and its relationship to organs at risk (OARs). The virtual gross tumor volumes were divided into four groups according to the Couinaud's classification. Several plans were made for each virtual target, and these plans were compared for the normal tissue complication probabilities (NTCP). For group I, NTCP improved as the number of the beam ports increased. However, plans with more than 5 ports had little advantage. For group II, plans with the beam directions from the anterior side showed better results. Group III contained many OARs near the target, which placed restrictions on the beam-directions. Multi-directional plans yielded a higher dose to the OARs than a simple two-port plan using right anterior oblique and posterior beam (RAO/PA). For group IV, a simple RAO/PA port plan was adequate for protection of remaining liver. NTCP can significantly vary between radiotherapy plans when the location of the tumor and its neighboring OARs are taken into consideration. The results in this study of optimal beam arrangements could be a useful set of guidelines for radiotherapy of hepatic tumors.

Comparison of occusal aspects in monolithic zirconia crown before and after occlusal adjustment during intraoral try-in: a case report (CAD/CAM으로 제작된 monolithic zirconia crown의 시적 전후 교합양상에 대한 비교)

  • Yong, Ki-Hoon;Shim, Jun-Sung
    • The Journal of Korean Academy of Prosthodontics
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    • v.52 no.3
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    • pp.246-251
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    • 2014
  • In case of prosthesis fabrication by CAD/CAM, location, area and contour of occlusal contacts can be adjusted so more functional occlusion can be acquired. Also, errors in a manufacturing process is reduced compared to cast metal prostheses and porcelain fused metal prostheses fabricated by conventional methods such as casting and porcelain build up. Therefore, prostheses by CAD/CAM show superior occlusion accuracy. Recently, virtual articulator function has been introduced to CAD/CAM system, which reproduces mandibular movement against maxilla. Thus, it is possible to consider occlusal interference in anterior/lateral movement as well as closing movement. There have been many studies on the marginal and internal fit of prostheses using zirconia but the occlusal fit of zirconia crown fabricated by CAD/CAM has not been researched as much. In this case report, 7 zirconia crowns were designed and fabricated by CAD/CAM for total 5 patients. The models of zirconia crowns before and after occlusal adjustment during intraoral try-in were scanned for occlusal contacts, which were compared to evaluate accuracy of prostheses and understand patterns of occlusal adjustment. Most of the occlusal adjustments were done on functional cusps and slopes of zirconia crown, and the magnitude of occlusal adjustment ranged from $15{\mu}m$ to $60{\mu}m$. In the zirconia crown fabricated with CAD/CAM systems, the occlusal adjustment is a necessary procedure, so additional procedures will be needed for compensating reduced mechanical properties.