• Korean Journal of Biological Psychiatry
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• v.14 no.1
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• pp.14-20
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• 2007

Objectives : The diagnosis of depression is based on a highly variable set of symptoms. Therefore, depression should not be viewed as a single disease, but a heterogenous syndrome comprised of different pathophysiologies. There are several subtypes of depression which were already incorporated in DSM-IV. This article provides a systematic review of pharmacological treatments of two recognized subtypes of depression-dysthymic disorder and atypical depression. Methods : Systematic search of relevant literatures on dysthymic disorder and atypical depression was performed by proposed search strategy of the Clinical Research Center for Depression of Korean Health 21 R&D Project. All identified literatures were carefully reviewed and classified according to SIGN grading system and summarized in a narrative manner. Results : For the treatment of dysthymic disorder and atypical depression, selective serotonin reuptake inhibitors( SSRIs) and moclobemide have more evidence than the other antidepressants. SSRIs and moclobemide showed superior tolerability than tricyclic antidepressants. Conclusions : The authors proposed treatment recommendations for dysthymic disorder and atypical depression by the methods of evidence-based medicine(EBM). However, guideline developing methods of EBM also have several inevitable limitations. Therefore, in the absence of clear and significant differences in efficacy, the choice of medication must be individualized for a particular patient based on psychiatrist's own clinical decision.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.5
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• pp.1300-1307
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• 1995

The effect of thermal stratification on the turbulent dispersion from a fine cylindrical heat source was experimentally examined in a wind tunnel with and without a strong temperature gradient. A 0.5 mm dia. nichrome wire was used as a line heat source. Turbulent intensities, r.m.s. value of temperature and convective heat fluxes were measured by using a hot-wire and cold-wire combination probe. The results show that the peack value and the spread of the vertical turbulent intensity for the stratified case are far lower than those in the neutral case, which indicates that the stable temperature gradient suppresses the vertical velocity component. All of the third order moments including heat fluxes measured in the stable condition have very small values than those of the neutral case. This nature suggests that the decrease of scalar fluctuations in the stably stratified flow is mainly due to the suppression ofthe turbulent diffusion processes by the stable stratification. A simple gradient model with a composite timescale which has a simple weighted algebraic mean between dynamic and thermal time scale yields reasonably good numerical values in comparison with the experimental data.

• Proceedings of the KSME Conference
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• 2001.11a
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• pp.174-179
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• 2001

In order to investigate the fracture behaviors(perforation modes) and resistance to perforation during ballistic impact of aluminum alloy plate, ballistic tests were conducted. Depth of penetration experiments with 5.56mm-diameter ball projectile launched into 25mm-thickness Al 5052-H34 targets were conducted. A powder gun launched the 3.55g projectiles at striking velocities between 0.6 and 1.0 km/s. radiography of the damaged targets showed different penetration modes as striking velocities increased. Resistance to perforation is determined by the protection ballistic limit($V_{50}$), a statistical velocity with 50% probability for complete perforation. Fracture behaviors and ballistic tolerance, described by perforation modes, are respectfully observed at and above ballistic limit velocities, as a result of $V_{50}$ test and Projectile Through Plates (PTP) test methods. PTP tests were conducted with $0^{\circ}$ obliquity at room temperature using 5.56mm ball projectile. $V_{50}$ tests with $0^{\circ}$ obliquity at room temperature were conducted with projectiles that were able to achieve near or complete perforation during PTP tests. The effect of various impact velocity are studied with depth of penetration.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.9
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• pp.1081-1092
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• 2004

The synthesis of Ni-catalyzed multi-walled carbon nanotubes and nanofibers on a catalytic metal substrate, using an ethylene fueled inverse diffusion flame as a heat source, was investigated. When the gas temperature was varied from 1,400K to 900K, approximately, carbon nanotubes with diameters of 20∼60nm were formed on the substrate. In the regions where the gas temperature was higher than 1,400K or lower than 900K, iron nanorods or carbon nanofibers were synthesized, respectively. Based on the quantitative analyses of large amount of SEM and TEM images, the nanotubes formed closer to the flame had a tendency of having larger diameters. HR-TEM images and Raman spectra revealed that carbon nanotubes synthesized had multi-walled structures with some defective graphite layers at the wall. Based on the graphite mode of the Raman spectra, it was believed that the optimal synthesis could be obtained as the substrate was positioned at between 5.5mm and 5.0mm, from the flame axis.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.9
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• pp.1094-1100
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• 2014

TEvaporator is key component in food, seawater distillation and waste water treatment system, which is basically to concentrate the raw liquid by evaporating the pure water under vacuum condition. The liquid concentration is performed through the membrane, electro-dialysis and evaporation. In this study, only the evaporating type was treated for evaluating the economic analysis with the various operating conditions. The results of this study showed that the performance of the OT-MSF desalination system is increased with decreasing the temperature difference between the neighboring evaporators, which means that the number of evaporators is increased, under the determined design conditions.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.10
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• pp.3344-3354
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• 1996

An experimental and numerical study on the three-dimensional natural convection-radiation conjugate heat transfer in the enclosure with heat generating chip has been performed. A 3-dimensional simulation model is developed by considering heat transfer phenomena by conduction-convection and radiation. Radiative transfer was analyzed with the discrete ordinates method. Experiments are conducted in order to validate the numerical model. Comparisons with the experimental data show that good agreement is obtained when the radiation effect is considered. The effects of the thermal conductivity of the substrate and power level on heat transfer are investigated. It is shown that radiation is the dominant heat transfer mode and the conductivity of the substrate has important effects on the heat transfer in the enclosure.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.1845-1850
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• 2003

The underground utility tunnels are important facility as a mainstay of country because of communication developments. The communication and electrical duct banks as well as various utility lines for urban life are installed in the underground utility tunnel systems. If a fire breaks out in this life-line tunnel, the function of the city will be discontinued and the huge damages are occurred. In order to improve the safety of life-line tunnel systems and the fire detection, the behaviors of the fire-induced smoke flow and temperature distribution are investigated. In this study we assumed that the fire is occurred at the contact or connection points of cable. Numerical calculations are carried out using different velocity of ventilation in utility tunnel. The fire source is modeled as a volumetric heat source. Three-dimensional flow and thermal characteristics in the underground tunnel are solved by means of FVM (Finite Volume Method) using SIMPLE algorithm and standard ${\kappa}-{\varepsilon}$ model for Reynolds stress terms. The numerical results of the fire-induced flow characteristics in an underground utility tunnel with different velocity of ventilation are graphically prepared and discussed.

• Korean Journal of Biological Psychiatry
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• v.16 no.1
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• pp.46-52
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• 2009

Objectives : The goal of this study was to compare the clinical characteristics of panic disorder respiratory subtype(PD-R) and non-respiratory subtype(PD-NR). Methods : 84 patients with panic disorder were enrolled and divided into 2 groups, 29 PD-R and 55 PD-NR. Diagnosis of panic disorder was evaluated using Diagnostic and Statistical Manual of Mental Disorders $4^{th}$ edition and Mini International Neuropsychiatric Interview. They were also measured with Hamilton Rating Scale for Anxiety(HAM-A), Hamilton Rating Scale for Depression(HAM-D), and Panic Disorder Severity Scale (PDSS). Results : PD-R group showed significantly higher scores in PDSS than those of PD-NR group(p=.027). After controlling for the severity of panic disorder and gender, PD-R group showed higher HAM-D and somatic anxiety subscale of HAM-A than those of PD-NR group. Furthermore, results of logistic regression analysis suggested that the somatic anxiety was a possible risk factor of PD-R(OR=1.404,p=0.009). Conclusion : These results suggest that somatic anxiety and depressive symptom would be important clinical characteristics of PD-R.

• Journal of computational fluids engineering
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• v.11 no.4 s.35
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• pp.32-38
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• 2006

The objective of this study is to evaluate the prediction accuracy of development large eddy simulation(LES) program for turbulent flow behind a bluff-body. The LES solver was implemented on parallel computer consisting 16 processors. To verify the capability of LES code, the results were compared with those of Reynolds Averaged Navier-Stokes(RANS) using standard ${\kappa}-{\varepsilon}$ model as well as experimental data. The results showed that the LES and RANS qualitatively well predicted the experimental results, such as mean axial, radial velocities and turbulent kinetic energy. In the quantitative analysis, however, the LES showed a better prediction performance than RANS. Specially, the LES well described characteristics of the recirculation zones, such as air stagnation point and jet stagnation point. Finally, the unsteady phenomena on the Bluff-body, such as the transition of recirculation region and vorticity, was examined with LES methodology.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.2 s.233
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• pp.224-231
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• 2005

The present study investigates flow characteristics in an optical disc drive (ODD). Detailed knowledge of the flow characteristics is essential to analyze flow-induced noise and vibration, forced convection and flow friction loss. The ODD used in a personal computer is used for the experiment and rotating velocity of disc is under the 4500 rpm. Time-resolved velocity component and velocity spectrum are obtained using the laser Doppler anemometry (LDA), and the flow patterns induced by rotating disc in the ODD are calculated by a commercial finite volume method at the same time. The results show that the front holes reduce flow-induced noise and the position of pickup body only affects flow near the window. Furthermore, it is possible for cooling of heat sources in the drive through measuring the flow fields under the tray. In addition, the numerical results are well matched up to the experimental results, therefore, the validation of the numerical results can be achieved. From the validation of numerical results, it is possible to predict the flow characteristics of the region where it is unable to conduct the experiment.