• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.4
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• pp.101-108
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• 2009

Purpose: Integrative studies have been made to review the correlationship of menstrual period with obesity and stress, and the relationship between stress and obesity has been reconfirmed through the study. Methods: Among the first time outpatients who visited the gynecological department of the OO oriental medical center from May 1st to September 1st of the year 2009, total 114 patients were included for the study by excluding the patients who received uterine hysterectomy, patients taking hormonal medications, and the patients who installed intrauterine devices. Survey has been made to investigate patients' age, menstrual period and duration of menstrual period. The investigation for the degree of obesity and stress was conducted as in below. Results: 1. From the menstrual cycle difference reviewed by Gonadosomatic index (GSI), the severe GSI group tended to show longer menstrual cycle than moderative GSI group. 2. From the menstrual cycle difference reviewed by Body Mass Index (BMI), longer menstrual cycle was observed from the abnormal BMI group than the normal BMI group. 3. No correlative probability values of GSI and BMI were observed. 4. Although the linear regression analysis result of BMI and GSI with the menstrual cycle did not show any statistical significance, the study resulted to show a tendency. Conclusion: Although the correlationship of menstrual cycle with obesity and stress did not show any significance, it is considered that the menstrual period could be affected by the combination of the variables rather than by independent variable.

• Proceedings of the Korean Information Science Society Conference
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• 2000.04a
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• pp.439-441
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• 2000

통신 기술의 발달은 컴퓨터를 활용한 정보 교환을 수월하게 만들었지만, 더불어 정보 유출의 가능성 또한 증가하였다. 특히 전자상거래와 같이 정보의 보호가 필요한 응용들도 급격히 활성화됨을 따라, 정보의 보안은 반드시 필요하며, 보안 서비스 중에서도 공정한 부인 봉쇄 서비스는 필수적이다. 기존에 제안된 부인 봉쇄 기법들은 보통 공정성을 위해 송.수신자는 중개자인 Trusted Third Party(TIP)를 두어 서로 통신한다. 하지만, 클라이언트수가 증가하면 중앙의 TTP에 네트웍 트래픽이 집중되어 효율적이지 못한다. 본 논문에서는 중앙 TTP에 집중되는 네트웍 트래픽량을 줄이기 위해 TTP를 분석시키는 새로운 부인봉쇄 프로토콜을 제시한다.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.4
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• pp.14-24
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• 2019

Objectives: The purpose of this review is to assess the effects of Chuna manipulation for postpartum pelvic pain and low back pain. Methods: To investigate the effects of Chuna manipulation for postpartum pelvic pain and low back pain, we searched the seven database (Korean Obstetrics and Gynecology, Oasis, National Digital Science Library, Pubmed, Cochrane Library, Embase, China National Knowledge Infrastructure) and manually checked related clinical trials up to May, 2019. Results: Seven studies were included in this review. Chuna and other manipulation (Osteopathy and Tuina) were effective in relieving postpartum pelvic pain and improving Oswestry Disability Index. Conclusion: This review suggests Chuna manipulation produces clinically relevant benefits for postpartum women with pelvic pain and low back pain. Further research may change estimates of effect, and larger, high-quality randomized controlled trials with robust comparison groups are recommended.

• The Journal of Korean Obstetrics and Gynecology
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• v.34 no.3
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• pp.157-174
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• 2021

Objectives: This case report aims to report the clinical effectiveness of the combination treatment of Korean medicine with Guibiondamtang-gamibang on Hwa-byung patients. Methods: Case 1 experienced stress at work and complained of chest discomfort, nausea, dizziness, insomnia. Case 2 experienced huge stress about money, and complained of palpitation, chest discomfort, dizziness and insomnia. They received combination treatment of Korean medicine during hospitalization. The treatment included Guibiondamtang-gamibang, acupuncture, moxibustion, pharmacoacupuncture, and fumigation. The effects were evaluated through Hwa-byung scale, instrument of oriental medical evaluation for Hwa-byung, insomnia severity index (ISI) and heart rate variability (HRV) test. Results: After the treatment, the clinical symptoms such as chest discomfort, palpitation, dizziness, nausea and insomnia were improved. Conclusions: This case report shows that the combination treatment of Korean medicine with Guibiondamtang-gamibang may be effective for treating Hwa-byung patients.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.2
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• pp.87-99
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• 2019

Objectives: The aim of this study was to analyse the domestic trends of Chuna manual therapy on Obstetrics and Gynecological Diseases in Korean literature. Methods: We searched for papers which had Chuna manual therapy through 2 related journals and 5 Korean web databases. All relevant papers were selected and extracted to be analyzed according to their study designs, academic journals, and target disease. Results: Nine papers belonged to four types of study designs, systematic review, randomized or non-randomized controlled trial and case report. And they were published in four kinds of academic journals. There were four papers about postpartum pain, two low back pain during pregnancy, and a stress urinary incontinence. The exact Chuna techniques were explained in only seven papers. All of papers have been shown that Chuna manual therapy is useful for obstetrics and gynecological diseases. Conclusions: It has been identified that Chuna manual therapy could be a good treatment for obstetrics and gynecological diseases. However, more clinical and well-designed studies with Chuna manual therapy will be needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.2
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• pp.50-70
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• 2019

Objectives: The purpose of this study was to show effectiveness of Korean medicine external treatment on bacterial vaginosis by analyzing randomized controlled clinical trials. Methods: We searched randomized controlled clinical trials related with Korean external treatment on bacterial vaginosis through national and overseas database and analyzed them in detail. Results: 15 articles were included according to our selection criteria and 2,176 women were involved. 1. All treatment groups were treated with intervention including Korean medicine external treatment and their results were statistically more effective than control groups. 2. External washing was the most frequently used method followed by vaginal tablet, fumigation and powder. 3. The most frequently used herbal medicine was Sophorae Radix followed by Phellodendri Cortex, Cindi Fructus, Dictamni Radicix Cortex and Kochiae Fructusa. 4. There were 4 studies reporting side effects of treatment and no significant side effects were observed. Conclusions: There was significant difference in the effectiveness of the intervention including Korean external therapy. Based on the analysis, it could be an effective way for the treatment of bacterial vaginosis in clinical practice.

• The Journal of Korean Obstetrics and Gynecology
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• v.34 no.2
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• pp.124-141
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• 2021

Objectives: The purpose of this study is to assess the efficacy of Jibaekjihwang-hwan and Daeboeum-hwan combination therapy for the treatment of precocious puberty. Methods: 6 databases were searched from the date of inception until April 2021 for relevant studies. We included randomized controlled trials (RCTs) and non-randomized controlled trials (nRCTs) which focused on effects of Jibaekjihwang-hwan and Daeboeum-hwan on precocious puberty. Results: Total 8 literatures were included in qualitative analysis and meta analysis on results was conducted on 4 synthesizable studies. The response rate was significantly higher in Jibaekjihwang-hwan and Daeboeum-hwan combination group than in conventional therapy group. Also, serum estradiol and follicle stimulating hormone (FSH) level were significantly lower in Jibaekjihwang-hwan and Daeboeum-hwan combination group than in conventional therapy group. Conclusions: It seems that combination therapy of Jibaekjihwang-hwan and Daeboeum-hwan can effectively reduce serum estradiol and FSH level while increasing response rate significantly. Further high quality studies are needed to supplement the efficacy and safety of combination therapy of Jibaekjihwang-hwan and Daeboeum-hwan on precocious puberty.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.3
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• pp.117-134
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• 2009

Purpose: In the theory of traditional medicine, Scutellariae Radix (SR) can clear away heat and remove dampness, purge the sthenic fire and remove toxic materials, cool blood and stop bleeding to prevent miscarriage. Recently, SR is known to have anti-cancer activity. For this reason, the present author designed to investigate the effect of SR on proliferation rates of cervical cancer cell line, then effects on genetic profile by SR. Methods: The genetic profile for the effect of SR on human derived cervical cancer cell line, SNU-703, was measured using microarray technique, and the functional analysis on these genes was conducted. Results: Total 519 genes were up-regulated and 606 genes down-regulated in cells treated with SR. Genes induced or suppressed by SR were all mainly concerned with metabolic process, regulation of biological process and protein binding. The network of total protein interactions was measured using cytoscape program, and some key molecules, such as TNFRSF1A, AKT1, MAPK3, and STAT3 that can be used for elucidation of therapeutical mechanism of medicine in future were identified. Conclusion: These results suggest possibility of SR as anti-cancer drug and also suggest that related mechanisms are involved in TNFRSF1A, AKT1, MAPK3, and STAT3 related signalling pathways.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.2
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• pp.163-171
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• 2009

Purpose: The purpose of this study is to report the effect of oriental treatments to postpartum depression. Methods: We treated 41 years old woman and 38 years old woman who had the postpartum depression. In the beginning of treatment, they had anxiety, depression, insomnia, fatigue. They were treated by oriental treatments such as herb medicine, acupuncture, moxa therapy. And then We compared postpartum depression before treatment with one after treatment by Edinburgh postnatal depression scale(EPDS). Results: After the oriental treatments, the clinical symptoms were improved and EPDS was reduced (one reduces from 18 to 10, the other reduces from 17 to 8). Conclusion: Oriental treatments are effective on postpartum depression. After this, further approach and study on postpartum depression might be needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.35 no.1
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• pp.75-90
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• 2022

Objectives: The purpose of this study protocol is firstly to investigate the status of Korean medical treatment of dysmenorrhea, and secondly to investigate effectiveness of the Clinical Pathway (CP) of dysmenorrhea and review the applicability. Methods: This is a multi-center observational study. The data will be prospectively collected from 14 Korean medicine clinics. 45 patients for each of the CP-applied and non-applied groups will be recruited to compare the degree of improvement in menstrual pain. All the diagnosis records, treatment methods, treatment results, adverse events, and medical expenses of patients with dysmenorrhea will be collected. We will investigate the proportion of patients who could be applied with CP, and the actual number of CP applications, and CP completion rate to evaluate the applicability. Additionally, the satisfaction survey will be used to collect feedback from medical staff members and patients. Results: The results of this study will be disseminated through peer-reviewed publications and scientific presentations. Conclusions: This study is expected to provide valuable data for application of standard Korean medicine clinical pathway for dysmenorrhea.