• Title/Summary/Keyword:  inhibition

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Maternal Behavioral Inhibition/Activation System and Preschooler's Emotional Intelligence : Mediated by Maternal Emotional Expressiveness (유아의 정서지능과 관련된 어머니의 행동억제/활성화체계 및 정서표현성)

  • Kim, Jihyun;Chung, Jee-Nha;Min, Sung Hye
    • Korean Journal of Child Studies
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    • v.28 no.4
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    • pp.113-126
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    • 2007
  • This study explored mediating effects of the maternal emotional expressiveness between maternal behavioral inhibition/behavioral activation system and children's emotional intelligence. subjects were 138 4- to 5-year-old preschoolers (92 boys, 46 girls) and their mothers. The maternal behavioral inhibition/behavioral activation system was measured by BIS/BAS(Behavioral Inhibition System/Behavioral Activation System, Carver & White, 1994), maternal emotional expressiveness was measured by the Self-Expressiveness in the Family Questionnaire (Halberstadt, 1995), and children's emotional intelligence was measured by the Emotional Intelligence Questionnaire (Lee, 1998). Data were analyzed by descriptive statistics and multiple regression analysis. Results were that maternal positive expressiveness mediated the effects of maternal BIS on children's self-understanding and maternal negative expressiveness mediated the effects of maternal BAS on children's self-regulation.

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A Basic Study on the Self-Corrosion Inhibition Function Identification of VA/E/MMA-Modified Mortar with Nitrite-Type Hydrocalumite (칼루마이트 및 VA/E/MMA 분말수지 병용 PMM의 자기방청기능 규명을 위한 기초적 연구)

  • Hong, Sun-Hee;Kim, Wan-Ki
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2011.11a
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    • pp.253-254
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    • 2011
  • The purpose of this study is to investigate chloride ion adsoption property of cement mortar using nitrite type hydrocalumite(calumite) with self-corrosion inhibition function. Superior corrosion inhibition function of the VA/E/MMA-modified mortars with calumite was ascertained from accelerated corrosion test in the previous study. In this study, VA/E/MMA-modified mortars with calumite were prepared with calumite contents of 0, 5, 10% and polymer-binder ratio of 0, 10%, and tested for chloride ion adsorption to make it clear how calumite gives self-corrosion inhibition function to cement mortar. As a result, chloride ion adsorption property of VA/E/MMA-modified mortars with calumite was improved by increasing calumite contents compared to unmodified mortar regardless of using VA/E/MMA terpolymer powder or not.

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Inhibition Enzyme-Linked Immunosorbent Assay (ELSIA) for Rapid Dection of Pseudomonas fluorescens in Raw Milk using IgY (난황 laY 항체의 Inhibition Enzyme-Linked Immunosorbant Assay(ELISA)법을 이용한 원유내 Pseudomonas fluorscens의 신속 검출 방법 개발)

  • 이승배;최석호;백두연
    • Food Science of Animal Resources
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    • v.20 no.3
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    • pp.231-235
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    • 2000
  • 원유에 존재하는 Ps. fluorescens의 균수를 신속하게 측정하기 위한 Inhibition Enzyme Linked Immunosorbant Assay (ELSIA)를 개발하기 위해 Ps, fluorescens(KCTC 2344)을 산란계에 접종하여 Ps.fluorescens에 대한 anti-Ps. fluorescens IgY 항체를 생산하고 그 항체의 역기를 ELISA로 측정한 결과 32일까지 항체 역가가 증가하였으며, 분리된 IgY 항체의 titer는 1:128,000으로 나타났다. Anti-Ps.fluorescens IgY 항체에대한 교차반응을 조사한 결과 그람양성균 Lactococcus faecalis, Staphylococcus aureus 뿐만 아니라 그람음성 균인 Achrombacter sal-monisida, Escherichia coil와도 교차반응을 거의 하지 않는 것으로 나타났다. Anti-Ps. fluo-rescens IgY 항체를 가지고 Inhibition ELISA 방법으로 Ps. fluorescens 균수를 신속한 측정할 수 있는 표준곡선을 작성한 결과 Ps. fluorescens균을 5.0$\times$$10^4$cfu/ml부터 5.0$\times$$10^{8}$cfu/ml 측정할 수 있는 것으로 나타났다.

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Antiinflammatory Evaluation and Synthesis of Benzothiazine Derivatives as Cyclooxygenase-2 Inhibitor (Cyclooxygenase-2 저해제로서의 benzothiazine 유도체 합성과 항염작용 평가)

  • 신혜순;박명숙;권순경
    • YAKHAK HOEJI
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    • v.44 no.3
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    • pp.272-278
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    • 2000
  • The antiinflammatory mechanism of NSAIDs is attributed to the reduction of prostaglandin synthesis by the direct inhibition of cyclooxygenase. Inhibition of prostaglandin production in organs such as stomach and kidney can result in gastric lesions, nephrotoxicity and increased bleeding. In this study, newly designed COX-2 inhibitors, synthesized 1,2-benzothiazine derivatives, were screened in vitro for selectivity of COX-1 and COX-2 inhibition properties. Lead compounds in the structure-activity relationship were studied to synthesize new highly selective COX-2 inhibitors.13 determine inhibitory effect of COX-2, synthesized 1,2-benzothiazine derivatives were screened with accumulation of prostaglandin by lipopolysaccharide (LPS) in aspirin-treated macrophages and murine macropharge cell. Some of synthesized 1,2-benzothiazine derivatives were shown to be effective as selective COX-2 inhibitory activity. Others exhibited a preferential inhibition of COX-2, although some COX-1 inhibitory activity was still present. As a conclusion, simple monomer derivatives were more active than dimer derivatives. Substitution of halogen (Br, C1) on the benzothiazine nucleus slightly enhanced inhibition activity.

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Growth Inhibition of Red Ginseng Extracts Against Human Tumor Cell Line by Clonogenic Assay (Clonogenic assay을 이용한 홍삼추출물의 인체종양세포에 대한 증식억제효과)

  • Kim, Chang-Han;Lee, Gyeong-Ho;Byeon, Eun-Gyeong
    • Journal of Ginseng Research
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    • v.22 no.3
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    • pp.188-192
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    • 1998
  • We established the model of clonogenic assay with human tumor cell line such as Calu-3 (lung carcinoma), HEC- lB (endometrial adenocarcinoma) , HEp-2 (larnyx carcinoma), Hs-5787 (breast carcinoma), K-562 (chronic myelogenous leukemia), SF-188 (brain carcinoma), SNU-1 (stomach carcinoma) and WiDr (colon carcinoma) . We investigated growth inhibition of solvent (EtOH, MeOH) and water (100$^{\circ}C$, 121$^{\circ}C$) extracts from Korean red ginseng by clonogenic assay. The results of clonogenic assay showed that EtOH extract had growth inhibition against Calu-3, SF-188 and SNU-1, MeOH extract had growth inhibition against Calu-3, Hs-5787, K-562, and WiDr, but water extract at 100$^{\circ}C$ and water extract at 121$^{\circ}C$ had not growth inhibition against used cell lines.

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A Product Inhibition Study on Adenosine Deaminase by Spectroscopy and Calorimetry

  • Saboury, Ali Akbar;Divsalar, Adeleh;Jafari, Ghasem Ataie;Moosavi-Movahedi, Ali Akbar;Housaindokht, Mohammad Reza;Hakimelahi, Hosain
    • BMB Reports
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    • v.35 no.3
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    • pp.302-305
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    • 2002
  • Kinetic and thermodynamic studies have been made on the effect of the inosine product on the activity of adenosine deaminase in a 50 mM sodium phosphate buffer, pH 7.5, at $27^{\circ}C$ using UV spectrophotometry and isothermal titration calorimetry (ITC). A competitive inhibition was observed for inosine as a product of the enzymatic reaction. A graphical-fitting method was used for determination of the binding constant and enthalpy of inhibitor binding by using isothermal titration microcalorimetry data. The dissociation-binding constant is equal to $140\;{\mu}M$ by the microcalorimetry method, which agrees well with the value of $143\;{\mu}M$ for the inhibition constant that was obtained from the spectroscopy method.

Growth inhibition of Perilla frutescens var. acuta extract (차조기 Perilla frutescens var. acuta.의 항균활성)

  • Lee, Eun-Sook;Seo, Bu-Il
    • The Korea Journal of Herbology
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    • v.20 no.2
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    • pp.83-89
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    • 2005
  • Objectives : This study was performed to investigate the effects of Perilla frutescens var. acuta extracts on growth inhibition of Streptococcus pyogenes KCTC 3208. Methods : Measured growth inhibition of Streptococcus pyogenes KCTC 3208 by concentration of the Perilla frutescens var. acuta. extract and collection periods of the Perilla frutescens var. acuta. and picking region of the Perilla frutescens var. acuta. Results : The Perilla frutescens var. acuta. extract is effective on retarding growth of Streptococcus pyogenes KCTC 3208. At 3% the growth of Streptococcus pyogenes KCTC 3208 was suddenly retarded. The stem of Perilla frutescens var. acuta. extract in a sunny place on June is more effective then its leaf. Conclusions : These results suggest that Perilla frutescens var. acuta. extract is effective in growth inhibition of Streptococcus pyogenes KCTC 3208.

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Removal of Microcystis aeruginosa using Pine Needle Extracts (솔잎추출액을 이용한 Microcystis aeruginosa 제거 연구)

  • Choi, Hee-Jeong
    • Journal of Korean Society on Water Environment
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    • v.33 no.1
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    • pp.8-14
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    • 2017
  • Microcystis aeruginosa (M. aeruginosa) is a cyanobacterium species that can form harmful algal blooms in freshwater bodies worldwide. The use of pine needle extract (PNE) to control nuisance algae by allelopathic inhibition will be environmentally friendly and promising. PNE removed successfully upto 98% of M. aeruginosa at the following optimal conditions: pH 7, $25^{\circ}C$ of temperature, 100 rpm of mixing rate, 5 min of mixing time. These results was indicated that the amount of 1 g/L PNE was removed 1g dryweight/L of M. aeruginosa. The kinetic data showed substrate inhibition kinetics and maximum growth rate was obtained when the M. aeruginosa was grown in medium containing 0.5 g/L of initial concentration of PNE. Different substrate inhibition models were fitted to the kinetic data and found the Luong model was best. The model predicted kinetic parameters were in agreement with the experimental findings. The natural extract, PNE, can be a promising inhibition due to its high efficiency and low dose requirements.

Inhibition of Transglutaminase and Microbial Transglutaminase Activity by Garlic

  • Lee, Nam-Hyouck;Takeuchi, Atsuyoshi;Konno, Kunihiko
    • Food Science and Biotechnology
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    • v.16 no.2
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    • pp.223-227
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    • 2007
  • Ground garlic inhibited the cross-linking reaction of myosin and incorporation of monodansylcadaverine (MDC) in salted Alaska pollack surimi catalyzed by transglutaminase (TGase). The component responsible for the inhibition was a thermostable, low molecular weight compound. The component also inhibited microbial transglutaminase (MTGase). The inhibition by garlic was reversibly recovered upon addition of 2-mercaptoethanol. The inhibitory component was therefore hypothesized to contain sulfhydryl groups within its structure. Alliin itself did not inhibit the cross-linking reaction. However, the addition of alliin together with garlic increased the inhibition. This result suggested that compounds derived from alliin was responsible for the inhibition of TGase activity.

Extract of Camellia sinensis as Green Inhibitor for the Corrosion of Mild Steel in Aqueous Solution

  • Fouda, Abd El-Aziz S.;Mekkia, Dina;Badr, Abeer H.
    • Journal of the Korean Chemical Society
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    • v.57 no.2
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    • pp.264-271
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    • 2013
  • Corrosion inhibition of mild steel used in water station in 35 ppm aluminum sulfate and 10 ppm chloride solution by Camellia sinensis leaves extract was studied using weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy techniques at $30^{\circ}C$. Results show that the inhibition efficiency increases with increasing concentration of the extract and decreases with increasing temperature. Inhibitive effect was afforded by adsorption of the extract's components which was found to accord with Langmuir adsorption isotherm. Inhibition mechanism is deduced from the temperature dependence of the inhibition efficiency and was further corroborated by the values of activation parameters obtained from the experimental data.