• Clinical and Experimental Pediatrics
• /
• v.58 no.6
• /
• pp.206-210
• /
• 2015

Purpose: The use of a 12-week steroid regimen (long-term therapy, LT) for the first episode of idiopathic nephrotic syndrome (NS) reportedly induces a more sustained remission and lower relapse rate than previous regimens, including an 8-week steroid regimen (short-term therapy, ST). Here, we assessed the potential for selective application of 2 steroid regimens (LT vs. ST) based on the days to remission (early responders [ER] vs. late responders [LR]) for the first idiopathic NS episode in children. Methods: Patients were divided into 4 subgroups (ST+ER, ST+LR, LT+ER, and LT+LR) according to the initial steroid regimen used and rapidity of response; the baseline characteristics, relapse rates, and cumulative percentage of children with sustained remission were then compared among the 4 subgroups. Results: Fifty-four children received ST, and the remaining 45 children received LT. As observed in previous studies, children receiving LT showed significantly lower relapse rates during the first year after the first NS episode than those receiving ST. The ST+ER group showed significantly lower relapse rates during the first one year and two years after the first NS episode than the the ST+LR group, whereas there were no significant differences of the relapse rates and duration to the first relapse between the ST+ER and LT+ER groups. Conclusion: We suggest that the initial steroid regimen in idiopathic NS patients can be shortened according to the duration to remission i.e., LT in patients achieving remission after the first week of steroid therapy, and ST in those achieving remission within the first week of steroid therapy.

• Asian-Australasian Journal of Animal Sciences
• /
• v.17 no.2
• /
• pp.159-163
• /
• 2004

Data pertaining to first lactation records of 316 Murrah buffaloes, progeny of 47 sires, maintained at NDRI Farm for a period of 18 years were analysed to construct selection indices and to examine their robustness by changing the relative economic values of different economic traits. A total of 120 selection indices were constructed for three sets of relative economic values ( 40 for each set) considering different combinations of seven first lactation traits viz. age at first calving (AFC), first lactation 305 day or less milk yield (FLMY), first lactation length (FLL), first calving interval (FCI), milk yield per day of first lactation length (MY/FLL), milk yield per day of first calving interval (MY/FCI) and milk yield per day age at second calving (MY/ASC). The three sets of relative economic values were based on economic values of different traits, 1% standard deviation of different traits and regression of different traits on FLMY. The 'optimum' indices for the first two sets had five traits each namely AFC, FLMY, FLL, FCI and MY/ASC giving improvement in aggregate genotype of Rupees 269.11 and Rs. 174.88, respectively. The accuracy of selection from both indices was 70.79 and 69.39%, respectively. The 'best' selection index from the third set of data again had five traits (AFC, FLMY, FLL, FCI and MY/FLL) giving genetic gain of Rs. 124.16 and accuracy of selection of 71.81%. The critcal levels or break-even points for FLMY for varying levels of AFC and FCI estimated from the "optimum index" suggested the need of enhancement of present production level of the herd or reduction of AFC or FCI. It was concluded that economic values of various first lactation traits were the most appropriate to construct selection indices as compared to other criteria of assigning relative economic weights in Murrah buffaloes.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.11
• /
• pp.6337-6340
• /
• 2013

Through retrospective analysis of 13 cases of magnetic resonance image (MRI) manifestations of atypical meningiomas confirmed by operation and pathology in the First Affiliated Hospital of Xinxiang Medical University, the objective of this study was to evaluate the diagnostic value of MRI in order to improve the accuracy rate of preoperative diagnosis. In this retrospective analysis of MRI findings for atypical meningiomas in First Affiliated Hospital of Xinxiang Medical University from January to July in 2012, the location, morphology and tumor signals and other tumor imaging characteristics were covered. In 13 cases of atypical meningioma patients of this group, most tumors were located at typical sites (10/13), mainly the falx cerebri, parasagittal, convexity, saddle area. Only two cases were at atypical locations, 1 in the cerebellar hemisphere and 1 in a lateral ventricle. Most of the tumors showed T1 and T2 isointensity signals, and necrosis, calcification, and peritumoral edema were always featured. DWI showed isointensity in 11 cases (11/13), and hyperintensity in 2. Some 9 cases had dural tail signs, 12 had accurate positioning (12/13), and 2 were postoperative recurrences. MRI has high value in the diagnosis of atypical meningiomas, with important roles in early clinical diagnosis, treatment and prognosis evaluation.

• Journal of Plant Biotechnology
• /
• v.3 no.2
• /
• pp.95-100
• /
• 2001

To select the section with shoot formation ability, the calli and shoot formation from three sections (first leaf including cotyledonary node, hypocotyl and cotyledon explants) of 5-days-seedlings of soybean were induced on MS medium supplemented with 1.0 mg/L BAP, 3% sucrose, and 0.3% gelrite for one month. The first leaf section exhibited the highest shoot formation rate (51%), followed the hypocotyl section (10%) and the cotyledon section (0%). The shoot formation rates and shoot number of the four excised sections (whole first leaf, a half of the first leaf, a third of the first leaf and only node) of the first leaf were also investigated on the same medium. A half of the first leaf explant and the third of the first leaf explant had higher shoot formation rates (76-80%) and numbers (3-4 / explants) than those in other two explants. Effects of six cytokinins (kinetin, zeatin, BAP, 2iP, PBA, and TDZ) on shoot formation were determined, using the half of the first leaf explants. Zeatin (1.0 mg/L) exhibited the highest in shoot formation rate (94%) and numbers (8 / explant). In addition, the combined effects of three cytokinins (zeatin, BAP, and TDZ; 0.5, 1.0, 2.0 mg/L, respectively) and an auxin (IAA; 0.0, 0.5, 1.0, 2.0 mg/L) were determined. The combination (1:1, v/v) of zeatin (1.0 mg/L) and IAA (1.0 mg/L) exhibited the highest in shoot formation rate (96%) and numbers (16 / explant), twice more than zeatin (1.0 mg/L) alone. The shoot cuttings were transferred and cultivated on the rooting media supplemented with only auxin, IBA at various concentrations. The highest root formation (8 / shoot) was achieved on the medium supplemented with 1.5 mg/L. After 4 weeks of cultivation, the plantlets with an extensive root system were transplanted in pots with a soil mixture of vermiculite and fine sand. Transferred to field, about 75% of the plantlets survived.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.4
• /
• pp.1605-1608
• /
• 2015

Purpose: To investigate the expression of Ki67 protein in papillary thyroid microcarcinoma(PTMC), and to analyze its clinical significance. Materials and Methods: Ki67 protein expression was evaluated in the tissues of 108 human PTMC and 50 other benign papillary hyperplasia of thyroid specimens using immunohistochemistry. Results: The expression intensity of Ki67 in PTMC and benign papillary hyperplasia of thyroid specimens were $1.45{\pm}1.83%$ and $0.46{\pm}0.46%$.The positive expression rates were 46.3% and 14%. There were significant differences between these two groups (p<0.01). There was no significant variation of the expression intensity and positive expression rates of Ki67 in PTMC with gender, age, position of the tumor and the level of TSH pre-operation (p>0.05), but these parameters varied with tumor size, invasion by membrane and cervical lymph node metastasis (p<0.05 or p<0.01). Conclusions: The expression of Ki67 in PTMC was related to tumor size, invasion by membrane and cervical lymph node metastasis, and could be the important indicator for judging clinical progress and estimating prognosis.

• Journal of Plant Biotechnology
• /
• v.30 no.4
• /
• pp.307-313
• /
• 2003

Fluorescent differential display (FDD) is a method for identifying differentially expressed genes in eukaryotic cells. The mRNA FDD technology works by systematic amplification of the 3' terminal regions of mRNAs. This method involve the reverse transcription using anchored primers designed to bind 5'boundary of the poly A tails, followed by polymerase chain reaction (PCR) amplification with additional upstream primers of arbitrary sequences. The amplified cDNA subpopulations are separated by denaturing polyacrylamide electrophoresis. To identify the genes involved in the development of first trap leaf, we applied a FDD method using mRNAs from leaf base, first trap leaf and flower tissue, respectively. We screened several genes that expressed specifically in first trap leaf. Nucleotide sequence analysis of these genes revealed that these were protease inhibitor (PI), myo-inositol-1-phosphate synthase and lipocalin-type prostaglandin D synthase. Northern blot analysis showed that these genes were expressed specifically in first trap leaf (in vivo and in vitro). FDD could prove to be useful for simultaneous scanning of transcripts from multiple cDNA samples and faster selection of differentially expressed transcripts of interest.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.3 no.1
• /
• pp.52-62
• /
• 1976

The purpose of this paper is to present the clinical findings obtained from the fourth year epidemiological study on dental caries prevalence in Korean children and to compare them with those from the first year study made in 1973 by Paik. The oral examination was performed for this study on 1,451 children, composed of 808 boys and 643 girls, at "K" elementary school located in Seoul, Korea. The following conclusions are drawn: 1. The df person rate of primary teeth is 90.30% for boys, 90.67% for girls, and 90.43% for all, which is 7.41% higher than the first year value. 2. The dft index per child of primary teeth is 4.26 for boys, 4.30 for girls, and 4.28 for all, which is 0.42 higher than the first year value. The dt index is 2.49 for boys, 2.44 for girls, and 2.47 for all, which is 0.59 lower than the first year value. The ft index is 1.77 for boys, 1.86 for girls, and 1.81 for all, which is 1.01 higher than the first year value. 3. The DMF person rate of permanent teeth is 70.24% for boys, 73.05% for girls, and 71.49% for all, which is 16.28% lower than the first year value. 4. The DMFT index per child of permanent teeth is 2.08 for boys, 2.50 for girls, and 2.27 for all, which is 1.31 lower than the first year value. The DT index is 1.44 for boys, 1.64 for girls, and 1.53 for all, which is 1.53 lower than the first year value. The FT index is 0.61 for body, 0.85 for girls, and 0.71 for all, which is 0.21 higher than the first year value. The MT index is 0.02 for all, which is statistically the same as the first year value.

• Journal of Korean Foot and Ankle Society
• /
• v.21 no.2
• /
• pp.55-60
• /
• 2017

Purpose: Stiffness in the first metatarsophalangeal joint after surgery for hallux valgus has been reported. The goal of this study was to test the efficacy of releasing plantar aponeurosis for improving the range of extension in the first metatarsophalangeal joint that was limited after hallux valgus surgery. Materials and Methods: Thirteen patients (1 man, 12 women [17 feet]; median age, 54.4 years; range, 44~69 years) with limited first metatarsophalangeal joint extension after hallux valgus surgery, who underwent an additional procedure of plantar aponeurosis release between March 2015 and August 2015, were included. Subsequently, the passive range of extension in the first metatarsophalangeal joint was evaluated via knee extension and flexion positions. Hallux valgus angle, inter-metatarsal angle, distal metatarsal articular angle, and talo-first metatarsal angle were measured on weightbearing dorsoplantar and lateral radiographs of the foot preoperatively. Results: The mean range of extension for the first metatarsophalangeal joint improved significantly, from $2.5^{\circ}$ to $40.9^{\circ}$ in the knee extension position (p<0.00). The mean extension range for the first metatarsophalangeal joint also improved, from $18.2^{\circ}$ to $43.2^{\circ}$ in the knee flexion position (p<0.00). In all patients, congruence of the first metatarsophalangeal joint was recovered. Conclusion: Plantar aponeurosis release is an effective additional procedure for improving the extension range of the first metatarsophalangeal joint after hallux valgus surgery.

• The Korean Journal of Emergency Medical Services
• /
• v.12 no.1
• /
• pp.43-52
• /
• 2008

I studied and analyzed current status about the necessity of Medical Oxygen Respiration First Aid when we perform first aid at emergency locations. As immediate and efficient first aid methods it is necessary to be able to use medical oxygen respiration equipments. I presented the basic data to develop and standardize education system on medical oxygen respiration first aid. Among those who were working at emergency locations in Korea from September 15th, 2005 to September 30th, 2005, I performed a survey on a professional group of 75 people and a non-professional group of 132 people. The results of the survey are summarized as follows. 1) There was difference between the professional group and the non-professional group on recognition about whether general public can perform medical oxygen respiration first aid(p<0.05). 2) On the necessity of medical oxygen respiration first aid, 93.2% of the total answered it is necessary and 6.8% answered it is unnecessary, so both groups thought it is very necessary(p>0.05). 3) On the importance of medical oxygen respiration first aid, 95.2% of the total answered it is important and 4.8% answered it is unimportant, so both groups thought it is very important(p>0.05). 4) On correspondence on necessity and importance of medical oxygen respiration first aid, there was a difference in thoughts between the professional group and the non-professional group(p<0.05). 5) On the necessity of education on medical oxygen respiration first aid, 98.1% of the total answered it is necessary and 1.9% answered it is unnecessary, so both groups thought it is very necessary(p>0.05).

• Journal of the Korean Society of School Health
• /
• v.24 no.1
• /
• pp.50-60
• /
• 2011

Purpose: This paper compares practical first aid training and theoretical first aid training in elementary schools. Methods: Research subjects were randomly selected and sorted into experimental and control groups. The former is one class (28 students) of the fifth grade students, and the latter is another class (30 students). In order to verify the effect of first aid training, we conducted theoretical as well as practical first-aid instruction about foreign body airway obstruction to the experimental group, but conducted only theoretical instruction with the control group. Data were analyzed by the ${\chi}^2$-test and t-test, one-way using the SPSS / win 12.0 program. The results were as follows (p=.05). Results: The first hypothesis was that the knowledge of an experimental group would be better than that of a control group. The analysis showed a significant difference (p=.000) between the two groups, supporting this hypothesis. The second hypothesis was that the experimental group would be more accurate than the control group. There was no because of (p=.000) between the two groups on this measure. The third hypothesis, that the two groups would vary over time on the measure of accuracy, was supported by the following observations: the experimental results were accumulated before, two days after and two weeks after the training (experimental group, p=.000, and control group, p=.000). This supports the third hypothesis that the technical performance accuracy levels of complete respiratory obstruction first aid vary over time. Conclusion: First aid training has to include practical education as well as theoretical education in the future, as part of a school's health education for elementary students. Health education classrooms should be prepared to teach first-aid theory and be supplied with equipment for practical exercises. Schools, communities, and private organizations need to carry out the practical education component periodically.