• Archives of Pharmacal Research
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• v.16 no.3
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• pp.251-253
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• 1993

Several new coumarinoyl and coumarionyl-1, 2, 4-triazole derivatives were synthesised via dipolar cycloaddition reactions with 3-coumainohydraziodoyl halide. Structure were based on elemental analysis and spectral data.

• Bulletin of the Korean Chemical Society
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• v.31 no.5
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• pp.1172-1176
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• 2010

Regioselective perfluorinated [3+2] cycloadducts and 1,2-adducts have been prepared by 1,3-dipolar cycloaddition between benzaldoxime NH-nitrone and perfluorinated alkene, perfluoro-2-methyl-2-pentene. Although the cycloaddition reaction is carried out at room temperature, the corresponding perfluorinated compounds are effectively produced in a high yield. In particular, the methoxy-substituted adducts (4 and 7a) show the self-assembled structure by intermolecular interactions. These derivatives were characterized by IR, $^1H$ and $^{19}F$ NMR, and the absolute structure of perfluorinated adducts was confirmed by X-ray crystallography.

• Archives of Pharmacal Research
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• v.13 no.1
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• pp.5-8
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• 1990

The cycloaddition of the newely synthesized 5-(2-thienyl)methylene derivatives of thiazolidinone-4-thiones, 2a-c to acrylonitrile (3a), ethylacrylate (3b), N-phenylmaleimide (6) and dimethyl fumarate (8) has been evaluated. Under thermal reaction conditions [4 +2] cycloaddition proceeds with complete site and regioselectivity to yield the cycloadduct, 4, 5, 7 and 9, respectively. The antimicrobial activities of some of the new products were tested.

• Bulletin of the Korean Chemical Society
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• v.35 no.5
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• pp.1403-1408
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• 2014

The cycloaddition reactions of the N-heterocyclic carbene boryl azide with methyl acrylate, butenone, and hexafluoropropene have been investigated theoretically. Solvent effects on these reactions have been explored by calculation that included a polarizable continuum model (PCM) for the solvent (C6H6). The title reaction could produce 4- and 5-substituted 1,2,3-triazolines, respectively. The reaction systems have the higher chemical reactivity with the low barriers and could be favored. Yet the smaller differences have been found to occur in energetics, and the cycloaddition reactions occur for s-trans conformations over s-cis conformations. The calculations indicated that the cycloaddition reaction of the alkenes have certain regioselectivity.

• Bulletin of the Korean Chemical Society
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• v.23 no.3
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• pp.511-514
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• 2002

• Bulletin of the Korean Chemical Society
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• v.23 no.3
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• pp.437-440
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• 2002

A variety of 1,2,3-triazole derivatives bearing acyclic sugar moieties of DHPG and iso-NDG were synthesised by Diels-Alder reaction. None of the new compounds display any interesting biological activity.

• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1515-1518
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• 2010

Regio- and diastereoselective 1,3-dipolar cycloaddition reactions of nitrones {(Z)-${\alpha}$-phenyl-N-methylnitrone (1a) and (Z)-${\alpha}$-propyl-N-butylnitrone (1b)} with electron-deficient perfluoro-2-methyl-2-pentene (2) lead to novel isoxazolidines {5-fluoro-5-pentafluoroethyl-4,4-bis-trifluoromethyl-2-methyl-3-phenyl-isoxazolidine (3a) and 2-butyl-5-fluoro-5-pentafluoroethyl-4,4-bis-trifluoromethyl-3-propyl-isoxazolidines (3b) respectively} as major constituents. These derivatives were characterized by IR, $^1H$ and $^{19}F$ NMR, GC-MS and NOE measurements, and the absolute structure of 3a was confirmed by X-ray crystallography.

• Bulletin of the Korean Chemical Society
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• v.32 no.5
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• pp.1554-1558
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• 2011

A novel and efficient method for the synthesis of 2,3-dihydrofurans bearing a variety of substituents on the dihydrofuran ring was achieved by the reaction of cyclic diazodicarbonyl compounds with styrene and vinyl acetate. The key strategy was AgBF$_4$/[Bmim]BF$_4$-catalyzed [3+2] cycloaddition. The synthesized dihydrofurans with an acetate group were further converted to the corresponding 3-acylfurans.

• Applied Chemistry for Engineering
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• v.27 no.3
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• pp.239-244
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• 2016

The catalytic applicability of various ionic liquids immobilized on different silica-supports such as amorphous, SBA, MCM and commercial silica for the cycloaddition of $CO_2$ and epoxides is reviewed in this work. The effects of different structures of supported ionic liquids and silica supports in the synthesis cyclic carbonate by the cycloaddition of $CO_2$ have been remarked. The studies revealed that ionic liquids possessing functional groups or metals exhibited increased catalytic performance towards cyclic carbonate synthesis. Moreover, the reusability of SSIL catalyst and mechanism for the cycloaddition of $CO_2$ were studied.

• Bulletin of the Korean Chemical Society
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• v.19 no.3
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• pp.335-339
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• 1998

Syntheses of carbapenam skeletons were achieved from 3-benzyloxypropanal through 1,3-dipolar cycloaddition. 3-Benzyloxypropanal was reacted with N-hydroxyglycine ester to give C-(2-benzyloxyethyl)-N-alkoxycarbonylmethylnitrone (6). 1,3-Dipolar cycloaddition of the nitrone with ethyl crotonate gave 3-(2-benzyloxyethyl)isoxazolidine (7). Compound 7 was transformed to 4-(2-hydroxyethyl)-2-azetidinone (11). Compound 11 was converted to 4-(2-iodoethyl)-2-azetidinone (13) or 4-phenylthiocarbonylmethyl-2-azetidinone (16) which was cyclized to give 6-(1-hydroxyethyl)carbapenam-3-carboxylate (14, 17).