• Korean Journal of Plant Resources
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• v.31 no.5
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• pp.466-477
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• 2018

In this study, the anti-inflammatory activities of the extracts of different parts of Hovenia dulcis such as leaves, stems, and roots were investigated. Among them, the roots extract (RE) showed the most potent suppressive effect against pro-inflammatory mediators in LPS-stimulated mouse macrophage cells. RE induced dose-dependent reduction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) and concomitantly reduced the production of NO and $PGE_2$. Additionally, pre-treatment with RE significantly suppressed the production of inflammatory cytokines, such as tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), interleukin $(IL)-1{\beta}$, and IL-6, as well as mRNA levels. Moreover, phosphorylation of mitogen-activated protein kinases (MAPKs) and nuclear translocation of nuclear factor-kappa B (NF-kB) were also strongly attenuated by RE in RAW264.7 cell. Furthermore, RE induced HO-1 expression through nuclear translocation of nuclear factor E2-related factor 2 (Nrf2) and increase HO-1 activity in RAW264.7 macrophages. Therefore, these results indicate that RE strongly inhibits LPS-induced inflammatory responses by blocking NF-kB activation, inhibiting MAPKs phosphorylation, and enhancing HO-1 expression in macrophages, suggesting that RE of H. dulicis and a major component, 27-O-protocatechuoylbetulinic acid could be applied as a valuable natural anti-inflammatory material.

• Ocean and Polar Research
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• v.39 no.4
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• pp.301-318
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• 2017

The production of Korean offshore fisheries has been gradually decreasing due to the severe depletion of offshore fisheries resources caused by excessive fishing efforts. The production of the offshore fisheries in 2016 was the lowest since 1975. So the federal and local governments in Korea adopted and implemented various fisheries management plans and policies in order to restore fisheries resources. However, these plans and polices have not been successful in re-establishing fisheries resources. Thus, in order to accurately diagnose the situation with regard to offshore fisheries, this study sought to estimate not only the return to scale by fishing gear of offshore fisheries, but marginal productivity of individual fishing gear based on production factors derived from offshore fisheries production functions. The study was organized in the following manner. First of all, this study estimates production functions of offshore fisheries. The Cobb-Douglas and the translog production functions are adopted as offshore fisheries production functions. Specifically, the functions are estimated by crew, vessels, and offshore resource as production factors. The offshore resource is estimated by the Clarke Yoshimoto Pooley model based on the surplus production model. Secondly, the fisheries production functions are extended to the fixed-effect model and the random-effect model with panel data. Thirdly, this study analyzes the return to scale of offshore fisheries and the marginal productivity of the production factors from the estimated offshore fisheries production function. In conclusion, this study suggests plans and countermeasures for productivity improvement by group (labor intensive or technology intensive) based on the characteristics of individual offshore fishing gear.

• Journal of computational fluids engineering
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• v.16 no.2
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• pp.24-29
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• 2011

Immersed boundary lattice Boltzmann method has been applied to analyze the characteristics of the self-propelled fish motion swimming robot. The airfoil NACA0012 with caudal fin stroke model was considered to examine the characteristics. The foil in steady forward motion and a combination of steady-state harmonic deformation produces thrust through the formation of a flow downstream from the trailing edge. The harmonic motion of the foil causes unsteady shedding of vorticity from the trailing edge, while forming the vortices at the leading edge as well. The resultant thrust is developed by the pressure difference formed on the upper and lower surface of the airfoil. and the time averaged thrust coefficient increases as Re increase in the region of $Re{\leqq}700$. The suggested numerical method is suitable to develop the fish-motion model to control the swimming robot, however It would need to extend in 3D analysis to examine the higher Re and to determine the more detail mechanism of thrust production.

• Transactions of the Korean hydrogen and new energy society
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• v.21 no.4
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• pp.264-270
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• 2010

Recently, the most promising methods for high purity hydrogen production are membranes separation such as polymer, metal, ceramic and composites. It is well known that Pd and Pd-alloys membranes have excellent properties for hydrogen separation. However, it has hydrogen embrittlement and high cost for practical applications. Therefore, most scientists have studied new materials instead of Pd and Pd-alloys. On the other hand, TiN powders are great in resistance to acids and chemically stable under high operating temperature. In order to get specimens for hydrogen permeation, the TiN powders synthesized were consolidated together with Co, Ni powders by hot press sintering (HPS). During the consolidation of powders at HPS, heating rate was 10 K/min and the pressure was 10 MPa. It was characterized by XRD, SEM. Also, we estimated the hydrogen permeability by Sievert's type hydrogen permeation membrane equipment.

• Journal of the Korea Safety Management & Science
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• v.6 no.4
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• pp.155-170
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• 2004

Among the semiconductor If-chips, unlike memory chips, a majority of Application Specific IC(ASIC) products are produced by customer orders, and meeting the customer specified due date is a critical issue for the case. However, to the one who understands the nature of semiconductor manufacturing, it does not take much effort to realize the difficulty of meeting the given specific production due dates. Due to its multi-layered feature of products, to be completed, a semiconductor product(called device) enters into the fabrication manufacturing process(FAB) repeatedly as many times as the number of the product specified layers, and fabrication processes of individual layers are composed with similar but not identical unit processes. The unit process called photo-lithography is the only process where every layer must pass through. This re-entrant feature of FAB makes predicting and planning of due date of an ordered batch of devices difficult. Parallel machines problem in the photo process, which is bottleneck process, is solved with restricted roll out algorithm. Roll out algorithm is a method of solving the problem by embedding it within a dynamic programming framework. Restricted roll out algorithm Is roll out algorithm that restricted alternative states to decrease the solving time and improve the result. Results of simulation test in condition as same as real FAB facilities show the effectiveness of the developed algorithm.

• Journal of Fashion Business
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• v.19 no.5
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• pp.48-62
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• 2015

The purpose of the study was to investigate how the Classification of the Joseon Dynasty's Beauty characteristics were expressed in a TV documentary focusing ona Re-mediation theory. The methods of study comprised of library research, Internet search, and using TV documentary program case studies. The work this Researcher makeup in the manufacture from the documentary in which the methods the Joseon. Dynasty expressed were selected. The literature, and preceding research, were referred to as a way to help organize the Joseon Dynasty's 'gi-saeng Hwang Jin-Hee', 'woman of royal family', and way of make-up of 'sadae-bu lady'. The TV documentary programs selected were 'MBC special' and '2 parts of channel A documentary special'. First, the improvisation of nature and simultaneity expressed in the Joseon Dynasty's usage of make-up is shown through the interview form reflecting the make-up tools and age direction of the scenes or expert. Second, the interactivity and reality are well seen through the row equivalent in which the model seems to directly use the dressing demonstration of the expert and cosmetics material. Third, the cultural expandability and unexpectedness show through the production of situations which are viewed from the explanation of the narration and letter subtitles and drama.

• IE interfaces
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• v.19 no.4
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• pp.316-323
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• 2006

In this study, based on Weibull proportional age reduction model and age replacement policy, we analyze economic life of cutting tool which allows re-grinding. Re-grinding task, usually for high-priced machining tools(e.g., broaching tool), is a kind of preventive maintenance activities to extend tool life at the completion of a lot production. The numerical results are also presented. Among the parameters of Weibull proportional age reduction model, the re-grinding effect parameter and Weibull shape parameter have a strong effect on economic tool life, and in the cost parameters, shortage cost is most sensitive. With further study on the parameter estimation of tool life process and cost function, this study can be expected to give more practical contribution to management of general machining tools.

• Journal of the Korea Society of Computer and Information
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• v.23 no.11
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• pp.103-109
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• 2018

This paper presents an idea and framework to automate a full cycle business process management and re-engineering by integrating traditional business process management systems, process mining, data mining, machine learning, and simulation. We build our framework on the cloud-based platform such that various data sources can be incorporated. We design our systems to be extensible so that not only beneficial for practitioners of BPM, but also for researchers. Our framework can be used as a test bed for researchers without the complication of system integration. The automation of redesigning phase and selecting a baseline process model for deployment are the two main contributions of this study. In the redesigning phase, we deal with both the analysis of the existing process model and what-if analysis on how to improve the process at the same time, Additionally, improving a business process can be applied in a case by case basis that needs a lot of trial and error and huge data. In selecting the baseline process model, we need to compare many probable routes of business execution and calculate the most efficient one in respect to production cost and execution time. We also discuss the challenges and limitation of the framework, including the systems adoptability, technical difficulties and human factors.

• Journal of the Korean Applied Science and Technology
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• v.35 no.4
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• pp.995-1002
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• 2018

Hairy root culture of ginseng is industrially prospected because the cultivation period of ginseng is relatively long. In this study, the effect of medium concentration and sucrose concentration on hairy root culture of ginseng was evaluated. The optimization of ginseng hairy roots transformed by Agrobacterium rhizogene were performed liquid medium. The MS(Murashinge & Skoog basal medium) concentration was selected with 1/2 strength MS and the optimal sucrose concentration was determined at 2-3%(w/v). At the optimum culture condition, The yield (the ratio of weight of grown hairy root cultures to weight of fresh ginseng hairy roots) and production rate of ginseng root were 19.42 times and 5.73 g/l-day. The major ginsenosides were Rb group, Re and Rg1. The produced total ginsenoside content in the solid medium was 9.87 (mg/g) and increased 1.34 times in the liquid medium (13.23 mg/g). In solid culture, the contents of ginsenosides Rb, Re and Rg1 were 2.14, 3.65 and 1.87 mg/g, respectively. In liquid culture, the contents of ginsenosides Rb, Re and Rg1 were 3.54, 4.12 and 2.63 mg/g, respectively.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2014.05a
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• pp.150-151
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• 2014

A mold of free-form concrete segment can be used only one time. Thus, the construction duration and cost are increased. The materials of the mold such as wood and metal have limitations due to the implementation and reuse. The review of the material of the mold for free-form concrete segment is needed to reduce duration and production cost. Phase change material can be used both to implement free-shape by heating and to produce mold after cooling. After using Phase change material can be re-used to mold by heating. The scope of this study is many kind of phase change materials for molding. The aim of this study is to analyze the phase change materials for production of changable mold for free-form concrete segment. In this study, the paraffin wax that is melted at 64℃ was selected by considering both the energy efficiency and the weather of Korea.