Anti-inflammatory Activity of Extracts of Hovenia dulcis on Lipopolysaccharides-stimulated RAW264.7 Cells
![]() |
Woo, Hyun Sim
(Division of Applied Life Science, Institute of Agriculture and Life Science, Gyeongsang National University)
Lee, Sun Min (Gyeongnam Department of Environmental Toxicology and Chemistry, Toxicology Screening Research Center, Korea Institute of Toxicology) Heo, Jeong Doo (Gyeongnam Department of Environmental Toxicology and Chemistry, Toxicology Screening Research Center, Korea Institute of Toxicology) Lee, Min-Sung (Plant Resource Industry Division, Forest Plant Industry Department, Baekdudaegan National Arboretum) Kim, Yeong-Su (Plant Resource Industry Division, Forest Plant Industry Department, Baekdudaegan National Arboretum) Kim, Dae Wook (Plant Resource Industry Division, Forest Plant Industry Department, Baekdudaegan National Arboretum) |
1 | Elbirt, K.K. and H.L. Bonkovsky. 1999. Heme oxygenase: recent advances in understanding its regulation and role. Proc. Assoc. Am. Physicians 111:438-447. DOI |
2 | Forstermann, U. and W.C. Sessa. 2012. Nitric oxide synthases: regulation and function. Eur. Heart J. 33:829-837. DOI |
3 | Horwood, N.J., T.H. Page, J.P. McDaid, C.D. Palmer, J. Campbell, T. Mahon, F.M. Brennan, D. Webster and B.M. Foxwell. 2006. Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF production, but not IL-6, production. J. Immunol. 176:3635-3641. DOI |
4 |
Ghosh, G., V.Y. Wang, D.B. Huang and A. Fusco. 2012. NF- |
5 | Gozzelino, R.,V. Jeney and M.P. Soares. 2010. Mechanisms of cell protection by heme oxygenase-1. Annu. Rev. Pharmacol. Toxicol. 50:323-354. DOI |
6 | Jang, B.C., J.H. Paik, S.P. Kim, D.H. Shin, D.K. Song, J.G. Park and S.I. Suh. 2005. Catalase induced expression of inflammatory mediators via activation of NF-kappaB, PI3K/AKT, p70S6K, and JNKs in BV2 microglia. Cell. Signal. 17:625-633. DOI |
7 | Jeong, D.H., K.B. Kim, M.J. Kim, B.K. Kang and D.H. Ahn. 2014. Anti-inflammatory activity of methanol extract and n-hexane fraction mojabanchromanol b from Myagropsis myagroides. Life Sci. 114:12-19. DOI |
8 | Kang, K.B., J.B. Jun, J.W. Kim, H.W. Kim and S.H. Sung. 2017. Ceanothane-and lupine-type triterpene esters from the roots of Hovenia dulcis and their antiproliferative activity on HSC-T6 Cells. Phytochemistry 142:60-67. DOI |
9 | Kaur, G, M.N. Hughes, C.J. Green, P. Naughton, R. Foresti and R. Motterlini. 2003. Interaction of bilirubin and biliverdin with reactive nitrogen species. FEBS Lett. 543:113-119. DOI |
10 | Kim, B.H., Y.T. Lee and K.H. Kang. 2010. Codonopsis lanceolate inhibits inflammation through regulation of MAPK in LPS stimulated RAW264.7 cells. Korean J. Oriental Physiol. Pathol. 24:80-84. |
11 |
Kim, D.H., J.H. Chung, J.S. Yoon, Y.M. Ha, S. Bae, E.K. Lee, K.J. Jung, M.S. Kim, Y.J. Kim and M.K. Kim. 2013. Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF- |
12 | Kim, H.N., S.B. Park, G.H. Park, H.J. Eo, J.H. Song, H.Y. Kwon and J.B. Jeong. 2018. Anti-inflammatory effects of the root extracts from Hibiscus syriacus in LPS-stimulated RAW264.7 cells. Korean J. Plant Res. 31:211-217. |
13 | Lee, J.W. and Y.J. Kang. 2018. Anti-inflammatory effects of Abeliopyllum distichum flower extract and associated MAPKs and NF-kB pathway in Raw264.7 cells. Korean J. Plant Res. 31:202-210. |
14 |
Majdalawieh, A. and H.S. Ro. 2010. Regulation of |
15 | Park, J.S., I.S. Kim, S.U. Rehman, C.S. Na and H.H. Yoo. 2015. HPLC determination of bioactive flavonoids in Hovenia dulcis fruit extracts. J Chromatogr Sci. 54:130-135. |
16 | Yang, J., S. Wu and C. Li. 2013. High efficiency secondary somatic embryogenesis in Hovenia dulcis Thunb. through solid and liquid cultures. Sci. World J. 718754:1-6. |
17 | Park, J.Y., J.Y. Moon, S.D. Park, W.H. Park, H. Kim and J.E. Kim. 2016. Fruits extracts of Hovenia dulcis Thunb. suppresses lipopolysaccharide-stimulated inflammatory responses through nuclear factor-kappaB pathway in Raw264.7 cells Asian Pac J Trop Med. 9:357-365. DOI |
18 | Tsan, M.F., J.E. White and C.L. Rosano. 1989. Modulation of endothelial GSH concentrations: effect of exogenous GSH and GSH monoethyl ester. J. Appl. Physiol. 66:1029-1034. DOI |
19 | Yang, H., K.H. Oh and Y.C. Yoo. 2015. Anti-inflammatory effect of hot water extract of Aronia fruits in LPS-stimulated RAW264.7 macrophages. J Korean Soc Food Sci. Nutr. 44:7-13. DOI |
![]() |