• 말소리와 음성과학
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• 제5권1호
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• pp.19-26
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• 2013

The aerodynamic characteristics (subglottal pressure (Ps) and mean airflow rate (MFR)), fundamental frequency (Fo), intensity (I), vocal efficiency (VE), and closed quotient (CQ) were compared during a sustained vowel /o/ sound under three conditions: in a comfortable loudness and pitch level (condition 1), in a maximum loudness level with a fixed pitch (condition 2), and in a maximum loudness level without a fixed pitch (condition 3). Also, multiple regression analyses were done to measure the aerodynamic characteristics affect on the VE and the CQ in each condition. The results showed the Fo, Ps, MFR, VE, and CQ increased as I increased with and without fixed pitch. Most notably, VE in condition 3 was the highest of all the conditions, but CQ was not very high. By the results of multiple regression analysis, VE was significantly affected by I and Ps in all conditions; Fo was the other main key for affecting VE in high pitch. However, none of the aerodynamic characteristics significantly affected CQ. As I increases, Fo should be increased by increasing Ps and VE. Therefore, researchers should consider and specify an a priori to Fo, Ps, and I when measuring VE to examine the complex and delicate vocal mechanism.

• Archives of Pharmacal Research
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• 제19권3호
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• pp.173-177
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• 1996

The Pneumococcus, Streptococcus pneumoniae, has an ample polysaccharide (PS) capsule that is highly antigenic and is the main virulence factor of the organism. The capsular PS is the source of PS vaccine. This investigation was undertaken to optimize the culture conditions for the production of capsular PS by type 4 pneumococcus. Among several culture media, brain heart infusion (BHI) and Casitone based medium were found to support luxuriant growth of pneumococcus type 4 at the same level. Therefore in this study, the Casitone based medium was used to study optimization of the culture condition because of BHI broth's high cost and complex nature. The phase of growth which accomodated maximum PS production was exponential phase. Concentrations of glucose greater than 0.8% did not enhance growth or PS production. Substitution of nitrogen sources with other resources or supplementation of various concentrations of metal ion (with the exception of calcium, copper, and magnesium ions) had adverse effects on growth and PS production. On the other hand, low level aeration and supplementation of 3 mg/l concentration of asparagine, phenylalanine, or threonine were beneficial for increased PS production. The synergistic effect of all the favorable conditions observed in pneumococcal growth assays provided a two-fold cumulative increase in capsular PS production.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.186-186
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• 1996

Streptococcus pneumoniae (pneumococcus), the most common cause of bacterial pneumonia, has an ample polysaccharide(PS) capsule that is highly antigenic and is the source of PS vaccine. This investigation was undertaken to optimize the culture conditions for the production of capsular PS by type 1 pneumococcus. Among several culture media, brain heart infusion (BHI) and Casitone based media were found to support luxuriant growth of pneumococcus type 1 at the same level. Because BHI medium is rather expensive and more complex than the Casitone based media, the Casitone based media was used to study optimization of the culture condition. The phase of growth which accomodated maximum PS production was logarithmic phase. Concentrations of glucose greater than 0.2% did not enhance growth or PS production. Substitution of nitrogen sources with other resources or supplemention of various concentrations of metal ion (with the exception of calcium ion) had adverse effects on growth and PS production. On the other hand, low level aeration was beneficial for increased PS production. Addition of 3 mg/I concentration of methionine, phenylalanine, and threonine were found to enhance growth and PS production. The synergistic effect of all the favorable conditions observed in pneumococcal growth assays provided a two-fold cumulative increase in capsular PS production.

• Elastomers and Composites
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• 제34권1호
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• pp.45-52
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• 1999

본 논문에서는 미세 상분리된 블럭 공중합체 박막의 특이상에서 금 입자들이 어떻게 자기응집(self assemble) 되고 잘 배열된 패턴을 형성하는지를 살펴보았다. 본 연구에서는 원통형 모폴로지를 갖는 PS-PB-PS 삼블럭 공중합체(30wt% PS) 박막(${\sim}100nm$)을 0.1wt% 톨루엔 용액으로부터 캐스팅하여 고분자 박막 형판(template)으로 사용하였다. 각각의 상이한 용매 증발조건으로부터 PB matrix내에 수평배열 PS cylinder와 수직 PS cylinder를 함께 갖는 막이 얻어졌다. 블럭 공중합체박막의 표면 및 bulk 몰폴로지를 살펴보기 위하여 단면투과전자현미경(TEM)을 사용하였다. Nano-scale 패턴을 얻기 위하여는 소량의 금입자를 블럭 공중합체 박막상에 증발시켰다. 캐스팅된 상태 그 대로의 박막형판이 사용되어질때 금입자들은 표면 장력이 적은 PB상에 우선적으로 자기응집(self as-semble)하여 비교적 잘 배열된 nano-scale의 패턴을 형성하였다. 그러나 열처리(annealing)에 의하여 표면장력이 적은 PB-rich충이 형성된 후에는 금입자의 자기응집에 의한 패턴은 관찰되지 않았다.

• 한국환경과학회지
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• 제11권4호
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• pp.375-382
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• 2002

The total hydrocarbon distribution of oil products obtained from the pyrolysis of four kinds of mixtures of polyethylene-polystyrene waste has been studied by multidimensional chromatography(high performance liquid chromatography followed by capillary gas chromatography)/mass spectrometry. Saturated, unsaturated and aromatic hydrocarbons in oil products were selectively pre-separated according to structural groups by HPLC and the weight fraction of each group was estimated by analysis of each component using GC-FID response factors. The hydrocarbon distribution of aliphatic fraction consists of $C_{5}$ to $C_{25}$ saturated and unsaturated hydrocarbons. And that of aromatics fraction consists of benzene, toluene, xylene, styrene, propenyl benzene, naphthalene, and some of derivatives. Pyrolysis temperature did not affect the ratio of total weight fraction of aliphatic over aromatic hydrocarbon distribution in case of PS only and PE-PS mixtures (1:1 and 1:4 wt. ratio) as a feed while affected the ratio of total wt. fraction in case of PE only. The optimal temperature for the maximum oil production was $600^{\circ}C$ for pyrolysis of PS and 1:1 and 1:4 mixtures of PE and PS. The optimal condition for aromatic recovery was $600^{\circ}C$ with 1:1 mixture of PE and PS. In this condition, aromatic was produced up to 90% of total oil product. The maximum yield of toluene, xylene, styrene, and propenyl benzene were 8.6, 8.9, 51.0 and 7.4% of feed for pyrolysis PS at $700^{\circ}C$, respectively. However, only 1.3% naphthalene was recovered at $700^{\circ}C$ with 1:1 PE:PS(by wt.).

• 대한환경공학회지
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• 제37권3호
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• pp.145-151
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• 2015

수중의 Sr과 Cs 이온을 제거하기 위하여 폴리술폰(polysulfone, PS)을 이용한 제올라이트 고정화로서 PS-zeolite 비드를 제조하였다. PS-zeolite는 SEM, XRD, FT-IR, TGA를 이용하여 특성 및 구조를 분석하였다. PS-zeolite 비드를 제조하기 위한 최적조건은 PS 1.25 g과 제올라이트 A 2 g이었다. 용액 pH의 증가에 따라 PS-zeolite 비드에 의한 Sr과 Cs 이온의 제거효율은 증가하였지만, pH 4 이상에서 일정하게 되었다. 본 연구에서 제조된 PS-zeolite 비드는 $Na^+$, $K^+$, $Mg^{2+}$ 및 $Ca^{2+}$와 같은 공존이온이 존재하더라도 Sr과 Cs 이온에 대한 높은 선택도를 나타내었다. 또한, 흡착과정에서 PS-zeolite 비드로부터 제올라이트 입자가 탈리되지 않았으며, PS-zeolite 비드는 SEM 이미지 상에서 구조가 유지되었다. PS-zeolite 비드에 의한 Sr과 Cs의 제거효율은 5회 흡착-탈착 실험을 반복하여도 90% 이상 유지되었다. 본 연구에서는 이 결과로서 PS-zeolite 비드가 Sr과 Cs 이온의 흡착제로서 적용가능하다 것을 확인할 수 있었다. 또한, PS-zeolite는 산업폐수처리를 위한 방사성 이온 제거용 흡착제로서도 적용이 가능할 것이다.

• Journal of Korean Neurosurgical Society
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• 제29권9호
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• pp.1161-1170
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• 2000

Objective : The transverse hippocampal slice is one of the most commonly studied in vitro models of mammalian brain physiology. However, despite its broad usage, there has been no standardization of slice preparation techniques or recording condition. It is well known that variations in recording conditions can result in profound different effects to neuronal responses. Evoked field potentials, recorded extracellularly, were used to investigate the effects of variations in hippocampal slice preparation protocol on hypoxia responses of CA1 neurones. Material & Methods : Before hypoxic injury, hippocampal slices were incubated for 4 hours. During incubation period, the slices were placed in a incubation chamber($21^{\circ}C$) for recovery from preparation injury and then transferred to recording chamber($34^{\circ}C$) for more recovery and baseline electric recording with current stimulation(0.1Hz). Various time periods in incubation chamber and recording chamber were applied to each experimental group(group 1=60min : 180min, group 2=90min : 150min, group 3=180min : 60min, time in incubation chamber : time in recording chamber) before 10 min hypoxia produced by replacing 95% $O_2$+5% $CO_2$ mixed gas to 95% $N_2$+5% $CO_2$ gas. Calcium, Magnesium ions and several drugs effecting on glutamate receptor also were studied. Recoveries from hypoxic injury of hippocampal slices were estimated by percent recovery of population spike(PS). Statistic analysis of study were performed using paired t-test. Results : The percent recovery of PS after 10min hypoxia was considerably enhanced by increasing the period of current stimulation during incubation period before hypoxic injury. Temperature effect on the result of this experiment was also studied(group 4) but the result from this showed no statistic significance. Low magnesium ion concentration of artificial CSF(Mg-free aCSF) during incubation period enhanced the recovery of PS but low calcium (calcium-free) and high magnesium ion concentration(2mM) reduced it after hypoxic injury. L-glutamate($100{\mu}M$) and AP-5($50{\mu}M$) had no effect on the recovery of PS but CNQX($10{\mu}M$) in artificial CSF during incubation period markedly enhanced the recovery of PS. Co-treatment of AP-5($50{\mu}M$), CNQX($10{\mu}M$) and high magnesium concentration(2mM) enhanced recovery of PS in immediate following period of hypoxic injury but the effect of cotreatment after then decayed rapidly and lost statistic significance. Conclusions : Judging from above results, the condition of baseline recording is important in observing the recovery of population spike after hypoxia, and the time and the condition should be controled more strictly to obtain reliable results.

• 대한인간공학회지
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• 제14권1호
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• pp.37-57
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• 1995

The purpose of this study was to investigate the elastic effect of deformation and restriction in wearing a support type panty stocking (PS). The study investigated deformation rate in all surface area, deformation rate in local area, length deformation rate, changes in slip and feeling of restriction under the standard laboratory condition. Two healthy adult females in twenties wore four types of PS. The result were as follows : The deformation rate in all surface area was 117 .approx. 132% in wearing support type PS, 157% in wearing mono type PS, due to the intensities of restriction. The deformation rate in local area was in order, course > oblique > wale direction. The largest deformation rate was observed in hip girth. Between the deformation rates in all surface and local areas was a high correlation acknowledged, especially the course direction showed a high correlation. Support type PSs showed more deformation and changes of slip than wool and mono type PS. Especially, changes of slip at the knee appeared greatly. The responses of restriction evaluated from a paired comparison method were in order, JS 2 > KS 4 > KS 9 > KS 5 > KS 1 > KM 3.

• The Journal of Korean Physical Therapy
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• 제26권5호
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• pp.290-295
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• 2014

Purpose: The purpose of this study was to assess the effects of robo-horseback riding with changes of pelvic tilting and speeds on muscle activities of trunk and lower limb in healthy adults. Methods: Thirty healthy adults were recruited for this study. Subjects performed robo-horseback riding at three pelvic postures (anterior tilting pelvic posture: AP, neutral pelvic posture: NP, posterior pelvic posture: PP) and different speeds (moderate and fast speed). Muscle activities were recorded from the trunk muscles (rectus abdominis [RA], T2 paraspinalis [T2 PS], L2 paraspinalis [L2 PS]) and lower limb muscles (rectus femoris [RF], vastus medialis [VM], vastus lateralis [VL], biceps femoris [BF], gastrucnemius [GCM]). Results: Significantly higher RA activities were observed under the PP condition than under the AP and NP conditions at both speeds. Significantly higher L2 PS activities were observed under the AP condition than under the PP and NP conditions at both speeds. Significantly higher T2 PS activities were observed under the AP condition than under the PP and NP conditions at fast speed. However, the muscle activities of the VM and GCM did not show significant changes with changes in pelvic posture at both speeds. All muscle activities were significantly higher under the fast speed than under the moderate speed in three pelvic postures. Conclusion: There were significant differences in the changes of pelvic tilting on muscle activities of trunk and lower limb were observed in healthy adults. NP condition can be introduced the most efficienct posture for muscle activities of trunk and lower limb in robo-horseback riding.

• 한국전자파학회논문지
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• 제25권5호
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• pp.515-525
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• 2014

본 논문에서는 저 위상잡음을 갖는 전압 제어 평판형 복합공진기 발진기(Vt-PCRO: Voltage-tuned Planar Composite Resonator Oscillator)를 설계, 제작하였다. 설계된 발진기는 공진기, 2개의 위상천이기, 증폭기로 구성된다. 공진기는 dual mode SIW(Substrate Integrated Waveguide) 공진기를 이용하여 구성하였으며, 약 40 nsec의 높은 군지연을 갖도록 하였다. 2개의 위상천이기 중(PS1, PS2: Phase Shifter 1 및 Phase Shifter 2) PS1은 $360^{\circ}$의 위상천이량을 가지며, 제작된 발진기의 전송선로 길이에 관계없이 개루프 이득(open loop gain) 발진조건을 만족하도록 한다. PS2는 약 $70^{\circ}$의 위상천이량을 가지며 발진 주파수 조정용으로 사용된다. 증폭기는 제작 시 발생한 큰 삽입손실의 문제를 보완하기 위해 2단으로 구성하였다. 개루프 이득 측정을 통해 발진 조건을 만족하는 PS1의 전압을 측정한 뒤, 폐루프로 구성하여 발진기를 구현하였다. 발진기 측정 결과, 5.345 GHz의 발진 주파수에서, 위상 잡음은 100 kHz offset 주파수에서 -130.5 dBc/Hz를 얻었다. 이때 출력 전력은 약 3.5 dBm, 전기적 주파수 조정 범위는 0~10 V의 조정 전압에서 약 4.2 MHz를 보였다.