• ALGAE
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• v.28 no.4
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• pp.331-341
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• 2013

Rhinomonas reticulata var. atrorosea G. Novarino is a photosynthetic marine flagellate that is known to have typical characteristics of cryptomonads. We examined the flagellar apparatus of R. reticulata var. atrorosea by transmission electron microscopy. The major components of the flagellar apparatus of R. reticulata var. atrorosea consisted of four types of microtubular roots (1r, 2r, 3r, and mr), a non-keeled rhizostyle (Rhs), mitochondrion-associated lamella (ML), two connections between basal bodies, a striated fibrous root (SR) and a striated fiber-associated microtubular root (SRm). Four types of microtubular roots originated near the ventral basal body and extended toward the left side of the basal bodies. The non-keeled Rhs originated at the Rhs-associated striated fiber, which was located between two basal bodies and extended into the middle of the cell. The ML was a plate-like fibrous structure associated with mitochondria and originating from a Rhs-associated fiber. It split into two parts and extended toward the dorsal-posterior of the cell to a mitochondrion. The SR and SRm extended parallel to the anterior lobe of the cell. The overall configuration of the flagellar apparatus in R. reticulata var. atrorosea was similar to the previously reported descriptions of those of Cryptomonas paramecium, C. pyrenoidifera, C. ovata, Hanusia phi, Guillardia theta, and Proteomonas sulcata. However, the flagellar apparatus system of R. reticulata var. atrorosea was more complex than those of other cryptomonad species due to the presence of an additional microtubular root and other distinctive features, such as a rhizostyle-associated striated fiber and large ML.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.2
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• pp.278-287
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• 2002

The objective of the paper was to calculate the pressure drop and to investigate the recirculation region of the conical orifices used in Kwang-yang Iron & Steel Company. The flow field with water used as a working fluid was the turbulent flow for Reynolds number of 2$\times$10$^4$. The effective parameters fur the pressure drop and the recirculation region were the conical orifice\`s inclined angle ($\theta$) against the wall, the interval(S) between orifices, the relative angle of rotation($\alpha$) of the orifices, the shape of the orifice's hole(circle, rectangle, triangle) having the same area, the number(N) of the orifice's holes having the same mass flow rate, and the thickness(t) of the orifices. It was fecund that the shape of the orifice's hole, the number of the orifice's holes and the thickness of the orifice affected the total pressure drop a lot and that the conical orifice's inclined angle against the wall, the relative angle of rotation of the orifices, the number of the orifice's holes and the thickness of the orifices affected the center location of the recirculation region. The PISO algorithm with FLUENT code was employed to analyze the flow field.

• Korean journal of food and cookery science
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• v.15 no.4
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• pp.418-425
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• 1999

The characteristics and yield of resistnat starch (RS) in waxy starches which were treated with 0.1N HCl were investigated. Hydrolysis rate of waxy starches were 0.32-0.88%. The yields of RS in waxy maize and waxy barley starches increased with acid treatment time up to 12hr and then decreased. The yield of RS in waxy rice starches increased with acid treatment up to 8hr and then decreased. The hydrolysis and yield of RS were different depending upon the varieties of starch source. Autoclaved normal maize starch showed a gel-like structure, but autoclaved normal maize starch showed crystal particle on the surface by SEM. The shape of autoclaved resistant starch was not different from acid treated ones. X-ray diffraction patterns of native and acid treated starches were all A-types. X-ray diffraction patterns of autoclaved waxy maize starches showed amorphous structures, however, those of RS showed all completely crystalline structure.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.6
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• pp.2795-2799
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• 2016

Purpose: To study histomorphological and immunohistochemical patterns of gastro-intestinal stromal tumours (GISTs) in Malaysia. Materials and Methods: A total of 29 GIST cases from Hospital Tuanku Ja'afar, Seremban, were studied retrospectively over a period of 10 years from January 2002 to December 2011. Patient demographic data like age, sex and etnicity were collected. Tumour characteristics like site, maximum dimension and specimen type were analysed. Evaluation was according to established criteria into very low, low, intermediate and high-risk categories. Immunohistochemical characteristics were also analysed. Results: The mean age of patients was 59.7 years. Males (59%) were found to be more commonly affected than females (41%). The Chinese (45%) were commonly affected than Malays (41%), and Indians (10%). The most common symptom was pain in the abdomen (13.8%). More than half of the cases were seen in stomach (53%). The tumour size ranged from 1.5 cm to 17 cm with a mean of 6.94cm. Microscopic findings revealed that the spindle cell type was the most common (76%). It was observed that the majority of the cases (48%) were categorised in the intermediate risk group. Immunohistochemical staining showed positivity for CD117 (78.6%), CD34 (71.4%), vimentin (86.2%), S-100 (27.6%), SMA (35.7%), PKC THETA (46.4%) and PDGRFA (67.9%).

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.39 no.5
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• pp.265-278
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• 2021

When a dangerous event arises for people inside a building and an immediate evacuation is required, it is important that suitable routes have been previously defined. These situations can happen especially when buildings are crowded, making the occupants have a very high vulnerability and can be trapped if they do not evacuate quickly and safely. However, in most cases, routes are considered based just on their proximity or short distance to the exit areas, and evacuation simulations that include more variables are not performed. This work aims to propose a methodology for building's indoor evacuation activities under the premise of processing simulation scenarios in multi-agent environments. In the methodology, importance indexes of simplified and validated geometry data from a BIM (Building Information Modeling) are considered as heuristic input data in a proposed algorithm. The algorithm is based on AP-Theta^* pathfinding and collision avoidance machine learning techniques. It also includes conditioning variables such as the number of people, speed of movement as well as reaction ability of the agents that influence the evacuation times. Moreover, collision avoidance is applied between people or with objects along the route. The simulations using the proposed algorithm are tested in NetLogo for diverse scenarios, showing feasible evacuation routes and calculating evacuation times in a multi-agent environment. The experimental results are obtained by applying the method in a study case and demonstrate the level of effectiveness of the algorithm, and the influence of the conditioning variables analyzed together when performing safe evacuation routes.

• Genes and Genomics
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• v.40 no.12
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• pp.1279-1285
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• 2018

Interdigitating dendritic cell sarcoma (IDCS) is an aggressive neoplasm and is an extremely rare disease, with a challenging diagnosis. Etiology of IDCS is also unknown and most studies with only case reports. In our case, immunohistochemistry showed that the tumor cells were positive for S100, CD45, and CD68, but negative for CD1a and CD21. This study aimed to investigate the causative factors of IDCS by sequencing the protein-coding regions of IDCS. We performed whole-exome sequencing with genomic DNA from blood and sarcoma tissue of the IDCS patient using the Illumina Hiseq 2500 platform. After that, we conducted Sanger sequencing for validation of sarcoma-specific variants and gene ontology analysis using DAVID bioinformatics resources. Through comparing sequencing data of sarcoma with normal blood, we obtained 15 nonsynonymous single nucleotide polymorphisms (SNPs) as sarcoma-specific variants. Although the 15 SNPs were not validated by Sanger sequencing due to tumor heterogeneity and low sensitivity of Sanger sequencing, we examined the function of the genes in which each SNP is located. Based on previous studies and gene ontology database, we found that POLQ encoding DNA polymerase theta enzyme and FNIP1 encoding tumor suppressor folliculin-interacting protein might have contributed to the IDCS. Our study provides potential causative genetic factors of IDCS and plays a role in advancing the understanding of IDCS pathogenesis.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.6
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• pp.177-185
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• 2018

There is a need to study dust separator screens with good drainage efficiency while effectively filtering suspended solids and other contaminants entering the intake pumping station, the drainage pumping station and the mediation pumping station, the cooling water inlet of the power plant, and the like. In this paper, Numerical studies were conducted for the optimal design of the dust separator screen using the Coanda effect. The shape of the dust separator screen is important, such as the right curvature radius $R_1$ at the top of the dust separator screen and the left curvature radius $R_2$ at the top, h is the height difference and shape between the screen and the accelerating plate, and ${\theta}$ is the inclination angle of the screen. A total of 4 shape factors were set and the effects of Coanda and drainage performance of each element were compared and analyzed, the optimum length and size of each shape element were derived by classifying the shape elements into direct and indirect influences. Finally, it was possible to effectively filter foreign matter by narrowing the screen spacing, and the drainage performance was analyzed and optimized through numerical studies of dust separator screen.

• Transactions of Materials Processing
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• v.27 no.6
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• pp.339-346
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• 2018

This study investigated the microstructure and wear properties of extruded hyper-eutectic Al-Si (15wt.%) alloy in an engine oil environment. The wear mechanism of the material was also analyzed and compared to conventional gray cast iron. In microstructural observation results of Al-15wt.%Si alloy, primary Si phase ($45.3{\mu}m$) and eutectic Si phase ($3.1{\mu}m$) were found in the matrix, and the precipitations of $Mg_2Si({\beta}^{\prime})$, $Al_2Cu({\theta}^{\prime})$ and $Al_6(Mn,Fe)$ were also detected. In the case of gray cast iron, ferrite and pearlite were observed. It was also observed that flake graphite ($20-130{\mu}m$) were randomly distributed. Wear rates were lower in the Al-Si alloy as compared to those of gray cast iron in all load conditions, confirming the outstanding wear resistance of Al-15wt.%Si alloy in engine oil environment. In the $4kg_f$ condition, the wear rate of gray cast iron was $6.0{\times}10^{-5}$ and that of Al-Si measured $0.8{\times}10^{-5}$. The microstructures after wear of the two materials were analyzed using scanning electron microscope (SEM) and electron backscatter diffraction (EBSD). The primary Si and eutectic Si of Al-Si alloy effectively mitigated the abrasive wear, and the Al matrix effectively endured to accept a significant amount of plastic deformation caused by wear.

• Advances in nano research
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• v.7 no.4
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• pp.233-240
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• 2019

The present research work reports in-vitro anti-cancer activity of biologically synthesized ZnO nanoparticles (ZnO NPs) against human carcinoma cells viz SCC-40, SK-MEL-2 and SCC-29B using Sulforhodamine-B (SRB) Assay. ZnO NPs were synthesized by a unique and novel biological route using Temperature-gradient phenomenon where the extract of combination of Catharanthus roseus (L.) G. Don (C. roseus), Azadirachta indica (A. indica), Ficus religiosa (F. religiosa) and NaOH solution were used as synthesis medium. The morphology of the ZnO NPs was characterized by Transmission Electron Microscopy (TEM). TEM images reveal that particle size of the samples reduces from 76 nm to 53 nm with the increase in reaction temperature and 68 nm to 38 nm with the increase in molar concentration of NaOH respectively. XRD study confirms the presence of elements and reduction in crystallite size with increase in reaction temperature and NaOH concentration. The diffraction peaks show broadening and a slight shift towards lower Bragg angle ($2{\theta}$) which represents the reduction in crystallite size as well as presence of uniform strain. The FTIR spectra of the extract show transmittance peak fingerprint of Zn-O bond and presence of bioactive molecules These NPs exhibit inhibition greater than 50% for SCC-40, SK-MEL-2 and SCC-29B cell lines and more than 50% cell kill for SCC-29B cells at concentrations < $80{\mu}g/ml$. Nanoparticles with smallest size have shown better anti-cancer activity and peculiar cell-selectivity. The combination of extracts of these plants with ZnO NPs can be used in targeted drug delivery as an effective anti-cancer agent, a potential application in cancer treatment.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.18 no.1
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• pp.59-64
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• 2019

In recent years, the HP-CRTM method, which has the ability to produce carbon fiber-reinforce plastic composites at high speeds, has come into the spotlight in the automotive parts industry, which demands high productivity. Multi-axial carbon fabric, an intermediate material used in this HP-CRTM molding process, consists of layered fibers without crimp, which makes it better in terms of tensile and shear strength than the original woven fabrics. The NCF (non-crimp fabric) can form the layers of the carbon fiber, which have different longitudinal and lateral directions, and ${\pm}{\theta}$ degrees, depending on the product's properties. In this research, preforms were made with carbon fibers of ${\pm}45^{\circ}$ and $0/90^{\circ}$, which were lamination structures under seven different conditions, in order to create the optimal laminated structure for automobile reinforcement center floor tunnels. Carbon fiber composites were created using each of the seven differently laminated preforms, and polyurethane was used as the base material. The specimens were manufactured in accordance with the ASTM D3039 standards, and the effect of the NCF lamination structure on the mechanical properties was confirmed by a tensile test.