• Nonlinear Functional Analysis and Applications
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• v.26 no.2
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• pp.237-272
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• 2021

The main purpose of the present paper is to study the asymptotic behavior near the origin of radial solutions of the equation 𝚫_p u(x) + u^q(x) + f(x) = 0 in ℝ^N\{0}, where p > 2, q > 1, N ≥ 1 and f is a continuous radial function on ℝ^N\{0}. The study depends strongly of the sign of the function f and the asymptotic behavior near the origin of the function |x|^λf(|x|) with suitable conditions on λ > 0.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4529-4532
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• 2013

Background: Acute normovolemic hemodilution (ANH) has been widely used to prevent the massive blood loss during hepatic carcinoma. The influences of ANH on coagulation function are still controversy, especially in elderly patients. The study observed ANH effects on coagulation function and fibrinolysis in elderly patients undergoing the disease. Materials and Methods: Thirty elderly patients (aged 60-70 yr) with liver cancer (ASA I or II) taken hepatic carcinectomy from February 2007 to February 2008 were randomly divided into ANH group (n=15) and control group (n=15). After tracheal intubation, patients in ANH group and control group were infused with 6% hydroxyethyl starch (130/0.4) and Ringer's solution, respectively. Blood samples were drawn from patients in both groups at five different time points: before anesthesia induction (T1), 30 min after ANH (T2), 1 h after start of operation (T3), immediately after operation (T4), and 24 h after operation (T5). Then coagulation function, soluble fibrin monomer complex (SFMC), prothrombin fragment (F1+2), and platelet membrane glycoprotein (CD62P and activated GP IIb/GP IIIa) were measured. Results: The perioperative blood loss and allogeneic blood transfusion were recorded during the surgery. The perioperative blood loss was not significantly different between two groups (p>0.05), but the volume of allogeneic blood transfusion in ANH group was significantly less than in control group ($350.0{\pm}70.7$) mL vs. ($457.0{\pm}181.3$) mL (p<0.01). Compared with the data of T1, the prothrombin time (PT) and activated partial thromboplastin time (APTT) measured after T3 were significantly longer (p<0.05) in both groups, but within normal range. There were no significant changes of thrombin time (TT) and D-dimer between two groups at different time points (p>0.05). SFMC and F1+2 increased in both groups, but were not statistically significant. PAC-1-positive cells and CD62P expressions in patients of ANH group were significantly lower than those at T1 (p<0.05) and T2-T5 (p>0.05). Conclusions: ANH has no obvious impact on fibrinolysis and coagulation function in elderly patients undergoing resection of liver cancer. The study suggested that ANH is safe to use in elderly patients and it could reduce allogeneic blood transfusion.

• Childhood Kidney Diseases
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• v.21 no.2
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• pp.47-52
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• 2017

Purpose: Renal ultrasonography has been widely used in children with renal disease. However, the relationship of renal echogenicity with renal pathology and function in children is not well known. Method: Ultrasound examination was performed in 75 patients undergoing renal biopsy for suspected renal disease in Konkuk University Medical Center from August 2005 to November 2015. We compared renal echogenicity to pathologic findings and renal function. Renal echogenicity was scored as 0 to 2 by comparing adjacent liver echogenicity. Three histologic characteristics were evaluated: glomerular changes, interstitial infiltration or fibrosis, and tubular atrophy. These were graded as 0 to 3, according to increasing severity. Laboratory results included urine albumin excretion and estimated glomerular filtration rate (eGFR). Results: Among pathologic findings, renal echogenicity revealed a positive correlation with interstitial infiltration or fibrosis (r=0.259, P=0.025), and with tubular atrophy (r=0.268, P=0.02). Renal echogenicity and glomerular changes were not correlated. Renal echogenicity showed a positive correlation with microalbuminuria (r=0.283, P=0.014), but a negative correlation with eGFR (r=-0.352, P=0.002). Conclusion: Increased renal echogenicity suggested severe interstitial infiltration or fibrosis and tubular atrophy among the pathologic findings. Moreover, increased echogenicity is correlated with increased urine albumin excretion and decreased eGFR. Echogenicity on ultrasonography is useful for determining the status of renal pathology and function.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.2
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• pp.69-78
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• 2013

Objectives : Health cooperative movement is of increasing concern among medical consumers and professionals in Korea. Most health cooperative clinics provide Western Medicine and Korean Medicine(KM) to patients. This study aimed to evaluate the primary care level of health cooperative KM clinics and compare it with local KM clinics in Korea. Methods : Face to face survey was performed at the 3 health cooperative KM clinics and 5 local KM clinics with the Korean Primary Care Assessment Tool (KPCAT). The KPCAT consists of 5 domains (21 items): first contact (5), coordination function (3), comprehensiveness (4), family/community orientation (4), and personalized care (5). Subjects were patients or guardians who had visited KM clinics five times or more during the last 3 months. We compared primary care scores of each domain between health cooperative KM clinics and local KM clinics. Results : Data were collected from 200 respondents (100 patients from health cooperative KM clinics and 100 local KM clinics). Total average scores of the KPCAT for health cooperative clinics and local KM clinics were $81.1{\pm}12.0$ and $75.4{\pm}9.5$, respectively. Among primary care domains, personalized care was the highest ($89.2{\pm}12.0$, $89.6{\pm}8.4$, respectively), and comprehensiveness function was the lowest ($68.5{\pm}22.5$, $54.5{\pm}22.0$, respectively). Significant differences between two groups were noted in comprehensiveness function (68.5 vs. 54.5, P=0.000), family-community orientation (79.5 vs. 73.0, P=0.004), first contact(89.2 vs 84.0, p=0.001) and coordination function(74.0 vs 68.7, p=0.025). Conclusions : Based on the patients assessment, health cooperative KM clinics provide more primary care-oriented services than local KM clinics. This means that health cooperative clinic can be one of alternatives to strengthen the primary health care in Korea. Future researches are recommended to measure patients satisfaction and treatment effectiveness in the health cooperative clinics.

• Annals of Occupational and Environmental Medicine
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• v.35
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• pp.27.1-27.12
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• 2023

Background: Environmental exposure is characterized by low concentration, chronic, and complex exposure. Traditional epidemiological studies show limitations in reflecting these characteristics since they usually focus on a single or very limited number of exposure factors at a time. In this study, we adopted the methodology of environment-wide association study (EWAS) to figure out the association of human liver function with various environmentally hazardous substances. Methods: We analyzed 2,961 participants from the Korean National Environmental Health Survey Cycle 4 (2018-2020). Using generalized linear model (GLM) analysis, we analyzed the association of 72 variables with 3 liver function indices (aspartate aminotransferase [AST], alanine aminotransferase [ALT], and gamma glutamyl transferase [GGT]). Finally, we visualized our results with Manhattan plot. Results: In GLM analysis, perfluorooctanesulfonate were positively associated with ALT (odds ratio [OR]: 2.2; 95% confidence interval [CI]: 1.39-3.46; p_adjusted = 0.0147) and perfluorodecanoic acid showed positive association with GGT (OR: 2.73; 95% CI: 1.36-5.5; p_adjusted = 0.0256). Plasma mercury showed positive association with GGT (OR: 1.45; 95% CI: 1.14-1.84; p_adjusted = 0.0315). Using a plastic container while keeping food in the refrigerator was associated with elevated GGT compared to using a glass container (OR: 1.51; 95% CI: 1.16-1.95; p_adjusted = 0.0153). 2-ethyl-5-oxohexyl phthalate, showed a negative trend with all 3 indices, with AST (OR: 0.54; 95% CI: 0.39-0.73; p_adjusted = 0.00357), ALT (OR: 0.5; 95% CI: 0.34-0.75; p_adjusted = 0.036), GGT (OR: 0.55; 95% CI: 0.4-0.76; p_adjusted = 0.00697). Bisphenol S and frequent use of sunblock cream showed negative association with ALT (OR: 0.77; 95% CI: 0.66-0.89), and GGT (OR: 0.25; 95% CI: 0.11-0.55), respectively. Conclusions: We conducted an exploratory study on environmental exposure and human liver function. By using EWAS methodology, we identified 7 factors that could have potential association with liver function.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.5
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• pp.504-514
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• 2014

An MMIC multi-function chip with a low DC power consumption for an X-band active phased array radar system has been designed and fabricated using a 0.5 ${\mu}m$ GaAs p-HEMT commercial process. The multi-function chip provides several functions: 6-bit phase shifting, 6-bit attenuation, transmit/receive switching, and signal amplification. The fabricated multi-function chip with a compact size of $16mm^2(4mm{\times}4mm)$ exhibits a gain of 10 dB and a P1dB of 14 dBm from 7 GHz to 11 GHz with a DC low power consumption of only 0.6 W. The RMS(Root Mean Square) errors for the 64 states of the 6-bit phase shift and attenuation were measured to $3^{\circ}$ and 0.6 dB, respectively over the frequency.

• Journal of Chest Surgery
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• v.21 no.1
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• pp.26-35
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• 1988

The effect of cardiopulmonary bypass on platelet count, platelet function, and bleeding time was studied in 60 patients. Platelet count was significantly reduced during and after cardiopulmonary bypass. Platelet function also had a reduced aggregation response to adenosine diphosphate. Bleeding time was prolonged to over 30 minutes during cardiopulmonary bypass and not returned to normal level until postbypass 1 hour. The amount of postoperative bleeding was proportional to the degree of decrease in platelet count and function, degree of decrease in platelet count and function. There was no significant correlation between duration of cardiopulmonary bypass and platelet count, platelet function, bleeding time, or amount of postoperative bleeding. Patients with cyanotic congenital heart disease showed a larger amount of postoperative bleeding than patients with acyanotic congenital heart disease [P<0.01], and this difference was due to the fact that platelet function was more significantly affected by cardiopulmonary bypass in cyanotic group. Patients using membrane oxygenator showed a less amount of postoperative bleeding than patients using bubble oxygenator [p<0.005] reflecting better preservation of platelet count and function by membrane oxygenator.

• Journal of Korean Society of Forest Science
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• v.58 no.1
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• pp.48-53
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• 1982

This experiment was carried out to distinguish between picea abies (L.) Karsten and Picea koraiensis Nak by the method of discriminant analysis which is used the metrical continuous characteristic on current inorphological plant taxanomy. The results are summarized as follows 1) The discriminant function and discriminant region from the experiment are Z(x)=Z($x_1,\;x_2$)=$0.000379x_1+0.004354x_2-0.311061$ or Z(x)=Z($x_1,\;x_2$=$0.000379(x_1-60.442800)+0.004354(x_2-66.185100)$, $$R_1=(x{\mid}0.000379x_1+0.004354x_2-0.311061{\geq_-}0)$$, $R_2$=($x{\mid}0.000379x_1+0.004354x_2-0.311061$ <0). 2) The probability of misclassification based on the above discriminant region is P($2{\mid}1$)=$P(1{\mid}2)$=0.444 therefore the probability of simultaneous misclassification of P($2{\mid}1$) and $P(1{\mid}2)$ is about 44.4%. 3) the probability of misclassification by the discriminant function resulted from the experiment if recorded as high but it is thought that there is a considerable meaning to perceive the probability of confidence about the discrimination better than its precision.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2001.09a
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• pp.71-74
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• 2001

AMB(Acid Mine Drainage), characterized as high concentration of metal & sulfate ions and low pH(2.0~4.0), is the world-wide problem wherever there is or has been mining activities. Though limestone has been generally used to neutralize AMD, There are metal hydroxide precipitation on the surface of limestone and excessive alkalinity formation which exceeds the regulation. In this research, concrete-recycled fine aggregate is selected for alternative neutralizing agent. Because fine recycled aggregate had more ANP than others in the preliminary research, the purpose of this research is to apply fine aggregate for AMD neutralization. Three columns packed with fine aggregates(2.5mm$O_3$) of it is calculated as 0.09(C-1), approximated 10% purity of limestone. Comparing with values of other columns(C-2: 0.01 and C-3: 0.01), there is variation of porosity and residence time induced from the precipitation of metal hydroxide. Consequently, 8 hours of HRT is enough to create adequate alkalinity and the function which could expect the variation of porosity(n) and residence time( $t_{R}$) should be applied to develop design function.lied to develop design function.

• Bulletin of the Korean Mathematical Society
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• v.22 no.2
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• pp.83-85
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• 1985

Let K be a real function field over a real closed field F. Then there exists an F-place .phi.:K.rarw.F.cup.{.inf.}. This is Lang's Existence of Rational Place Theorem (6). There is an equivalent version of Lang's Theorem in (4). That is, if K is a function field over a field F, then, for any ordering P$_{0}$ on F which extends to K, there exists an F-place .phi.: K.rarw.F'.cup.{.inf.} where F' is a real closure of (F, P$_{0}$). In [2], Knebusch pointed out the converse of the version of Lang's Theorem is also true. By a valuation theoretic approach to Lang's Theorem, we have found out the following generalization of Lang and Knebusch's Theorem. Let K be an arbitrary extension field of a field F. then an ordering P$_{0}$ on F can be extended to an ordering P on K if there exists an F-place of K into some real closed field R containing F. Of course R$^{2}$.cap.F=P$_{0}$. The restriction K being a function field of F is vanished, though the codomain of the F-place is slightly varied. Therefore our theorem is a generalization of Lang and Knebusch's theorem.