• Title/Summary/Keyword: $PM_{10}$$PM_{2.5}$$PM_1$

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Evaluation of Tangential Fields Technique Using TOMO Direct Radiation Therapy after Breast Partial Mastectomy (유방 부분 절제술 후 방사선 치료 시 TOMO Direct를 이용한 접선 조사의 선량적 유용성에 관한 고찰)

  • Kim, Mi-Jung;Kim, Joo-Ho;Kim, Hun-Kyum;Cho, Kang-Chul;Chun, Byeong-Chul;Cho, Jeong-Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.23 no.1
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    • pp.59-66
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    • 2011
  • Purpose: Investigation of the clinical use of tangential fields technique using TOMO direct in comparison to conventional LINAC based radiation therapy after breast partial mastectomy. Materials and Methods: Treatment plans were created for 3 left-sided breast cancer patients who had radiation therapy after breast partial mastectomy by using wedged tangential fields technique, field in field technique (FIF), TOMO Direct, TOMO Direct intensity modulated radiation therapy (IMRT) under the normalized prescription condition ($D_{90%}$: 50.4 Gy/28 fx within CTV). Dose volume histogram (DVH) and isodose curve were used to evaluate the dose to the clinical target volume (CTV), organ at risk (OAR). We compared and analyzed dosimetric parameters of CTV and OAR. Dosimetric parameters of CTV are $D_{99}$, $D_{95}$, Dose homogeneity index (DHI: $D_{10}/D_{90}$) and $V_{105}$, $V_{110}$. And dosimetric parameters of OAR are $V_{10}$, $V_{20}$, $V_{30}$, $V_{40}$ of the heart and $V_{10}$, $V_{20}$, $V_{30}$ of left lung. Results: Dosimetric results of CTV, the average value of $D_{99}$, $D_{95}$ were $47.7{\pm}1.1Gy$, $49.4{\pm}0.1Gy$ from wedged tangential fields technique (W) and FIF (F) were $47.1{\pm}0.6Gy$, $49.2{\pm}0.4Gy$. And it was $49.2{\pm}0.4$ vs. $48.6{\pm}0.8Gy$, $49.9{\pm}0.4$ vs. $49.5{\pm}0.3Gy$ Gy for the TOMO Direct (D) and TOMO Direct IMRT (I). The average value of dose homogeneity index was W: $1.1{\pm}0.02$, F: $1.07{\pm}0.02$, D: $1.03{\pm}0.001$, I: $1.05{\pm}0.02$. When we compared the average value of $V_{105}$, $V_{110}$ using each technique, it was the highest as $34.6{\pm}9.3%$, $7.5{\pm}7.9%$ for wedged tangential fields technique and the value dropped for FIF as $16.5{\pm}14.8%$, $2.1{\pm}3.5%$, TOMO direct IMRT as $7.5{\pm}8.3%$, $0.1{\pm}0.1%$ and the TOMO direct showed the lowest values for both as 0%. Dosimetric results of OAR was no significant difference among each technique. Conclusion: TOMO direct provides improved target dose homogeneity over wedged tangential field technique. It is no increase the amount of normal tissue volumes receiving low doses, as oppose to IMRT or Helical TOMO IMRT. Also, it simply performs treatment plan procedure than FIF. TOMO Direct is a clinical useful technique for breast cancer patients after partial mastectomy.

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Effect of temperature on pharmacokinetics of nalidixic acid and piromidic acid in black rockfish Sebastes schlegeli following oral administration (조피볼락, Sebastes schlegeli에 경구투여된 nalidixic acid 및 piromidic acid의 약물동태에 미치는 수온의 영향)

  • Jung, Sung-Hee;Seo, Jung-Soo;Jee, Bo-Young;Kim, Jin-Woo;Park, Myoung-Ae
    • Journal of fish pathology
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    • v.24 no.1
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    • pp.29-37
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    • 2011
  • Effects of temperature ($13{\pm}1.5^{\circ}C$, $23{\pm}1.5^{\circ}C$) on the pharmacokinetic properties of nalidixic acid (NA) and piromidic acid (PA) were studied after oral administration to cultured black rockfish, Sebastes schlegeli. Serum concentrations of NA and PA were determined using HPLC-UV detector after a single dosage of 60 mg/kg body weight. At $23{\pm}1.5^{\circ}C$, the peak serum concentrations of NA and PA, which attained at 24 h post-dose, were 5.87 and $0.43\;{\mu}g/ml$, respectively. At $13{\pm}1.5^{\circ}C$, the peak serum concentrations of NA and PA, which attained at 10 h post-dose, were 6.22 and $1.57\;{\mu}g/ml$, respectively. Better absorption of PA was noted at $13{\pm}1.5^{\circ}C$ compared to $23{\pm}1.5^{\circ}C$. However, absorption of NA was not affected significantly by temperature. The elimination of NA and PA from serum of black rockfish was considerably faster at $23{\pm}1.5^{\circ}C$ than at $13{\pm}1.5^{\circ}C$. The kinetic profile of absorption, distribution and elimination of NA and PA in serum were analyzed by fitting to a one compartment model, with WinNonlin program. The AUC, $T_{1/2}$, $T_{max}$ and $C_{max}$, respectively, were: $161.25\;{\mu}g{\cdot}h/ml$, 0.15 h, 12.29 h and $8.91\;{\mu}g/ml$ at $23{\pm}1.5^{\circ}C$, and $134.12{\mu}g{\cdot}h/ml$, 0.18 h, 8.79 h and $5.00\;{\mu}g/ml$ at $13{\pm}1.5^{\circ}C$ with NA; $41.57\;{\mu}g{\cdot}h/ml$, 0.58 h, 8.24 h and $0.21\;{\mu}g/ml$ at $23{\pm}1.5^{\circ}C$, and $40.36\;{\mu}g{\cdot}h/ml$, 0.59 h, 5.04 h and $1.20\;{\mu}g/ml$ at $13{\pm}1.5^{\circ}C$ with PA.

Selection of superior breeding colonies of Apis mellifera based on performance-testing (능력검정에 의한 우량 종봉 선발에 관한 연구)

  • Son, Young-Ik;Cha, Yong-Ho;Choi, Kwang-Soo
    • Current Research on Agriculture and Life Sciences
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    • v.19
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    • pp.17-22
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    • 2001
  • The study was conducted to establish the method of performance test of honeybee queens under Korean environment. Colony performances of Apis mellifera were tested based on wintering ability, colony population and honey yield in Sangju, Korea from November, 1999 to October, 2001. The results of performance-testing on the honeybee colonies are summarized as follows: The colony weights measured before and after wintering in 1999~2000 season were averaged $22.6{\pm}2.6kg$ and $20.1{\pm}2.6kg$, respectively, showing the decrease of $2.5{\pm}0.7kg$. During 2000~2001 winter season, the colony weight before wintering was $22.6{\pm}2.3kg$ and was decreased by $2.3{\pm}0.6kg$. The number of combs well covered with bees was $13.1{\pm}4.6$ as measured on the 22nd of May. 2000 and $16.0{\pm}3.8$ on the 21st of May. 2001, respectively. The rate of supering colonies were 50% and 98.5% in 2000 and 2001, respectively. The amount of honey production was $12.7{\pm}8.6kg$ per colony in 2000, and $14.2{\pm}7.6kg$ per colony with unselected queens and $23.5{\pm}4.9kg$ per colony with selected-tested queens in 2001, which were harvested two times during main nectar flow season of black locust, Robinia peseudoacasia.

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The Effects of Corn Silage and Roughages Feeding Systems on Milk Yield and Compositions (옥수수 Silage 및 조사료 급여 체계가 유량 및 유성분에 미치는 영향)

  • 이상무;이준영
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.24 no.1
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    • pp.43-52
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    • 2004
  • This study was carried out to determine the effect of corn silage and roughage feeding systems on milk yield and milk compositions. The experimental design was allotted into 3 treatments according to the feeding systems of rice straw(rice straw+concentrate: T1), corn silage(corn silage + concentrate: T2) and TMR treatment(Total mixed rate : roughage + concentrate: T3). This research was carried out from Oct. 1988 to Mar. 1999 at Kimcheon Kyungbook. The results obtained were summarized as follows: 1. The milk yield increased upon T2(31.9$\pm$3.2kg) > T3(29.6$\pm$3.8kg) > T1 treatment(22.5$\pm$2.0kg)(P<0.05), but cows with T2 and T3 produced the highest at third parity while T1 at forth parity. 2. The milk fat percentage was the highest at T3 treatment(3.79$\pm$0.31%), and on the other hand T1 treatment appeared the lowest percentage. Cow at 2nd parity produced the highest milk fat contend over the other parity. 3. There was no significant difference in protein content between treatments and parity, but T2 and T3 were higher than T1 4. Treatment did not affact content of SNF even though T2 and T3 of the SNF revealed to higher than T1. T5 was T3(12.51$\pm$0.57%)>T1(11.71$\pm$0.62%)>T2 treatment(11.52$\pm$0.55%). These were not significant. 5. Somatic cell counts were the highest at T1(39.6 ${\times}$ $10^4$cell/ml), but T2 treatment was the lowest as 28.7 ${\times}$ $10^4$ cell/ml. These results indicates that com silage(T2) and TMR treatment(T3) could be recommended

Assessment of Exposure to and Risk of Formaldehyde and Particulate Matter (PM10 and PM2.5) by Time Activity Applying Real-Time Indoor and Outdoor Monitoring (실내·외 실시간 모니터링을 활용한 폼알데하이드 및 미세먼지(PM10, PM2.5)의 거주시간별 노출 및 위해도 평가)

  • Yoon, Danki;Namgoung, Sunju;Kong, Hyekwan;Hong, Hyungjin;Lim, Huibeen;Park, Sihyun;Lee, Hyewon;Lee, Jungsub;Lee, Cheolmin
    • Journal of Environmental Health Sciences
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    • v.45 no.6
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    • pp.646-657
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    • 2019
  • Objectives: The purpose of this study was to suggest methods to investigate continuous monitoring of concentration levels and assess the exposure of individuals considering the actual time activity of residents for formaldehyde and particulate matter (PM10, PM2.5) in the indoor and outdoor air of a house, assess the health risks of children and adults based on the results of the exposure assessment, and provide basic data on studies for assessing exposure and health risks in Korea in the future. Methods: The concentration levels of formaldehyde and particulate matter were measured in a family home in Gyeonggi-do Province from April 25 to July 31, 2019, using electrochemical sensors (formaldehyde) and light scattering sensors (PM10, PM2.5). Risk assessment by the duration of exposure by time activity was performed by dividing between weekdays and weekends, and indoors and outdoors. Results: The greatest level of carcinogenic risk from inhaling formaldehyde was indoors during the weekdays for both children and adults. For children, the risk was at 7.5 per approximately 10,000 people, and for adults, the risk was at 4.1 per approximately 10,000 people. PM10 and PM2.5 also showed the greatest values indoors during the weekdays, with children at 1.7 people and 1.4 per approximately 100 people, respectively, and adults at 8.2 per approximately 1,000 and 1.8 per approximately 100 people, respectively. Conclusions: The risks of formaldehyde, PM10 and PM2.5 were shown to be high indoors. Therefore, consideration of exposure assesment for each indoor pollutant and management of indoor air quality is necessary.

Reproductive Behavior of the Barn Swallow (Hirundo rustica) in Korea - A Case Study in Gwangju Metropolitan City - (한국에 도래하는 제비(Hirundo rustica)의 번식행동 - 광주광역시를 사례로 -)

  • Kim, Sang-jin;Oh, Hong-shik
    • Korean Journal of Environment and Ecology
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    • v.31 no.2
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    • pp.127-134
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    • 2017
  • This study was conducted to identify the reproductive behavior of the barn swallow. The study was carried out in Gwangju, Korea during the 2013 breeding season. In the morning, the nest-building frequency was 14.2~31.0 trips/h (10.2~19.8 trips/h by male and 4.0~11.4 trips/h by female). The nest-building activity took 7.6~15.9 min/h (4.8~8.1 min/h by male and 2.8~8.0 min/h by female). The nest-building time by female ($40.0{\pm}27.9sec/trip$) was about 1.5 times longer than the nest-building time by male ($26.1{\pm}15.5sec/trip$). Only the female incubated the eggs. The Incubation time was $50.6{\pm}17.5min/h$ (84%) at 6h, 24.5 min/h (40.8%) at 7h and 15.6 min/h (26.0%) thereafter. During daytime, the female incubation time showed a highly significant difference (p<0.001), and the incubation time at 6h was higher than that at other times. There was a significantly negative correlation between female incubation time and the mean air temperature(p<0.05). The frequency of feeding was $385.2{\pm}66.9trips/nest$ in the daytime ($219.2{\pm}37.1trips/nest$ by male and $166.0{\pm}30.8trips/nest$ by female). The frequency of feeding per hour was $32.1{\pm}12.3trips/h$ ($18.3{\pm}7.8trips/h$ by male and $14.3{\pm}4.5trips/h$ by female). The frequency of feeding per hour showed a significant difference in the range of 10h(p<0.05) and 15h(p<0.01) by sex. The time of feeding by female ($40.9{\pm}83.3sec/trip$) was longer than the time of feeding by male ($12.3{\pm}31.0sec/trip$). The juvenile defecation frequency was $45.6{\pm}8.4times/nest$ per day and showed a positive correlation with feeding frequency (p<0.05). The results of this study will be helpful in understanding the reproductive behaviors of the swallow adapted to the environment in Korea.

The Antioxidant and Nitrite Scavenging Activity of Wild Grape(Vitis coignetiea) Wine (머루와인의 항산화성 및 아질산염 소거능)

  • Park, Hyun-Sil
    • Journal of the East Asian Society of Dietary Life
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    • v.21 no.1
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    • pp.68-73
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    • 2011
  • Total anthocyanin and color intensity contents of wild grape wine were $4.3{\pm}0.3%$ and $10.2{\pm}0.8%$, respectively. The contents of total phenols and flavonoid in wild grape wine were $18.8{\pm}3.9$ mg/100 g, $0.5{\pm}0.2$ mg/100 g, respectively. Total mineral content in wild grape wine was $22.6{\pm}0.2$ mg/100 g and the 10 minerals of the potassium content ($5.3{\pm}0.2$ mg/100 g) was the highest. Electron donating abilities of wild grape juice at concentration of 1,000 ${\mu}L/mL$ were $90.4{\pm}1.8%$. Reducing power of wild grape wine at concentration of 1,000 ${\mu}L/mL$ were 0.932. The electron donating abilities and reducing power were increased significantly by increased the sample concentration in the reaction mixture. The nitrite scavenging ability was dependent on pH of reaction mixture and sample concentration. The nitrite scavenging ability of wild grape win was $76.3{\pm}1.3%$ at concentration of 1,000 ${\mu}L/mL$ under pH 1.2.

Anterior Lumbar Interbody Fusion with Stand-Alone Interbody Cage in Treatment of Lumbar Intervertebral Foraminal Stenosis : Comparative Study of Two Different Types of Cages

  • Cho, Chul-Bum;Ryu, Kyeong-Sik;Park, Chun-Kun
    • Journal of Korean Neurosurgical Society
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    • v.47 no.5
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    • pp.352-357
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    • 2010
  • Objective : This retrospective study was performed to evaluate the clinical and radiological results of anterior lumbar interbody fusion (ALIF) using two different stand-alone cages in the treatment of lumbar intervertebral foraminal stenosis (IFS). Methods : A total of 28 patients who underwent ALIF at L5-S1 using stand-alone cage were studied [Stabilis$^{(R)}$ (Stryker, Kalamazoo, MI, USA); 13, SynFix-LR$^{(R)}$ (Synthes Bettlach, Switzerland); 15]. Mean follow-up period was 27.3 ${\pm}$ 4.9 months. Visual analogue pain scale (VAS) and Oswestry disability index (ODI) were assessed. Radiologically, the change of disc height, intervertebral foraminal (IVF) height and width at the operated segment were measured, and fusion status was defined. Results : Final mean VAS (back and leg) and ODI scores were significantly decreased from preoperative values (5.6 ${\pm}$ 2.3 ${\rightarrow}$ 2.3 ${\pm}$ 2.2, 6.3 ${\pm}$ 3.2 ${\rightarrow}$1.6 ${\pm}$ 1.6, and 53.7 ${\pm}$ 18.6 ${\rightarrow}$ 28.3 ${\pm}$ 13.1, respectively), which were not different between the two devices groups. In Stabilis$^{(R)}$ group, postoperative immediately increased disc and IVF heights (10.09 ${\pm}$ 4.15 mm ${\rightarrow}$ 14.99 ${\pm}$ 1.73 mm, 13.00 ${\pm}$ 2.44 mm ${\rightarrow}$ 16.28 ${\pm}$ 2.23 mm, respectively) were gradually decreased, and finally returned to preoperative value (11.29 ${\pm}$ 1.67 mm, 13.59 ${\pm}$ 2.01 mm, respectively). In SynFix-LR$^{(R)}$ group, immediately increased disc and IVF heights (9.60 ${\pm}$ 2.82 mm ${\rightarrow}$ 15.61 ${\pm}$ 0.62 mm, 14.01 ${\pm}$ 2.53 mm ${\rightarrow}$ 21.27 ${\pm}$ 1.93 mm, respectively) were maintained until the last follow up (13.72 ${\pm}$ 1.21 mm, 17.87 ${\pm}$ 2.02 mm, respectively). The changes of IVF width of each group was minimal pre- and postoperatively. Solid arthrodesis was observed in 11 patients in Stabilis group (11/13, 84.6%) and 13 in SynFix-LR$^{(R)}$ group (13/15, 86.7%). Conclusion : ALIF using stand-alone cage could assure good clinical results in the treatment of symptomatic lumbar IFS in the mid-term follow up. A degree of subsidence at the operated segment was different depending on the device type, which was higher in Stabilis$^{(R)}$ group.

Comparison of PM2.5 Concentrations by Measurement Method (측정 방법에 따른 PM2.5 농도 비교)

  • Ghim, Young Sung;Choi, Yongjoo;Park, Jisoo;Kim, Pilho;Han, Yu Kyung
    • Journal of Korean Society for Atmospheric Environment
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    • v.33 no.5
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    • pp.515-520
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    • 2017
  • $PM_{2.5}$ concentrations were measured using a cyclone, impactor (the U.S. Environmental Protection Agency well impactor ninety-six, WINS) and optical particle counter (OPC) at a campus site located in Yongin for the period August 2014 through March 2017. The concentrations from cyclone (Y) were generally higher than those from impactor(X); the best-fit line was Y=1.22X+5.64. The ratios of $PM_{2.5}/PM_{10}$ ranged from 0.61 to 0.66 when $PM_{2.5}$ concentrations from cyclones in selected studies were converted into those from impactors using a regression equation in this study. The slope of the best-fit line between OPC and impactor was close to 1 at 0.95, while that between OPC and cyclone was 0.72. After sampling, the flow rate in the low-volume air sampler with cyclone decreased by 3% on average, which did not have a significant effect on measured concentrations.

Reproductive Performance of Crossbred and Indigenous (Desi) Dairy Cows under Rural Context at Sirajgonj District of Bangladesh

  • Paul, Ashit Kumar;Al-Maruf, Abdullah;Jha, Pankaj Kumar;Alam, M. Golam Shahi
    • Journal of Embryo Transfer
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    • v.28 no.4
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    • pp.319-324
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    • 2013
  • This study was conducted among 120 different breed cows at selected areas of Sirajgonj district from March to July 2010 to compare the reproductive performance of crossbred and Desi cows at farmer's level. The results showed that the average daily milk yield of Desi, Shahiwal ${\times}$ Desi, Friesian ${\times}$ Desi and Jersey ${\times}$ Desi cows was $2.3{\pm}0.2$, $4.9{\pm}0.9$, $6.0{\pm}1.0$ and $5.7{\pm}0.9$ liters, respectively. The milk yield of crossbred cows ($5.5{\pm}0.6$ liters/day) was significantly (p<0.01) higher than Desi cows ($2.3{\pm}0.2$ liters/day). The average age at puberty of Shahiwal ${\times}$ Desi, Friesian ${\times}$ Desi and Jersey ${\times}$ Desi was significantly (p<0.01) lower than that of Desi breed. The crossbred cows had significantly (p<0.01) lower pubertal age ($20.4{\pm}1.2$) than Desi ($25.9{\pm}1.1$). The age at first calving in Desi cows was significantly (p<0.01) higher ($37.6{\pm}1.1$ months) than crossbred cows ($31.2{\pm}1.3$ months). The average gestation length of Desi, Shahiwal ${\times}$ Desi, Friesian ${\times}$ Desi and Jersey ${\times}$ Desi was $289.9{\pm}1.4$, $285.0{\pm}0.0$, $285.0{\pm}4.2$ and $282.1{\pm}2.4$ days, respectively. It is suggested that the overall reproductive performance of Friesian ${\times}$ Desi, Jersey ${\times}$ Desi and Shahiwal ${\times}$ Desi cows were better than that of Desi cow.